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Modelling for the robust design of layered resonators for ultrasonic particle manipulation

Modelling for the robust design of layered resonators for ultrasonic particle manipulation
Modelling for the robust design of layered resonators for ultrasonic particle manipulation
Several approaches have been described for the manipulation of particles within an ultrasonic field. Of those based on standing waves, devices in which the critical dimension of the resonant chamber is less than a wavelength are particularly well suited to microfluidic, or “lab on a chip” applications. These might include pre-processing or fractionation of samples prior to analysis, formation of monolayers for cell interaction studies, or the enhancement of biosensor detection capability. The small size of microfluidic resonators typically places tight tolerances on the positioning of the acoustic node, and such systems are required to have high transduction efficiencies, for reasons of power availability and temperature stability. Further, the expense of many microfabrication methods precludes an iterative experimental approach to their development. Hence, the ability to design sub-wavelength resonators that are efficient, robust and have the appropriate acoustic energy distribution is extremely important. This paper discusses one-dimensional modelling used in the design of ultrasonic resonators for particle manipulation and gives example of their uses to predict and explain resonator behaviour. Particular difficulties in designing quarter wave systems are highlighted, and modelling is used to explain observed trends and predict performance of such resonators, including their performance with different coupling layer materials.
acoustic radiation force, layered resonators, robust design, particle manipulation
0041-624X
521-528
Hill, Martyn
0cda65c8-a70f-476f-b126-d2c4460a253e
Townsend, Rosemary J.
0452b21c-a758-4d4a-925b-1511d9296d62
Harris, Nicholas R.
237cfdbd-86e4-4025-869c-c85136f14dfd
Hill, Martyn
0cda65c8-a70f-476f-b126-d2c4460a253e
Townsend, Rosemary J.
0452b21c-a758-4d4a-925b-1511d9296d62
Harris, Nicholas R.
237cfdbd-86e4-4025-869c-c85136f14dfd

Hill, Martyn, Townsend, Rosemary J. and Harris, Nicholas R. (2008) Modelling for the robust design of layered resonators for ultrasonic particle manipulation. Ultrasonics, 48 (6-7), 521-528. (doi:10.1016/j.ultras.2008.06.007).

Record type: Article

Abstract

Several approaches have been described for the manipulation of particles within an ultrasonic field. Of those based on standing waves, devices in which the critical dimension of the resonant chamber is less than a wavelength are particularly well suited to microfluidic, or “lab on a chip” applications. These might include pre-processing or fractionation of samples prior to analysis, formation of monolayers for cell interaction studies, or the enhancement of biosensor detection capability. The small size of microfluidic resonators typically places tight tolerances on the positioning of the acoustic node, and such systems are required to have high transduction efficiencies, for reasons of power availability and temperature stability. Further, the expense of many microfabrication methods precludes an iterative experimental approach to their development. Hence, the ability to design sub-wavelength resonators that are efficient, robust and have the appropriate acoustic energy distribution is extremely important. This paper discusses one-dimensional modelling used in the design of ultrasonic resonators for particle manipulation and gives example of their uses to predict and explain resonator behaviour. Particular difficulties in designing quarter wave systems are highlighted, and modelling is used to explain observed trends and predict performance of such resonators, including their performance with different coupling layer materials.

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More information

Submitted date: 11 June 2007
Published date: November 2008
Keywords: acoustic radiation force, layered resonators, robust design, particle manipulation
Organisations: EEE

Identifiers

Local EPrints ID: 266904
URI: http://eprints.soton.ac.uk/id/eprint/266904
ISSN: 0041-624X
PURE UUID: 1866ceef-034b-4a44-988f-2166f4502fcc
ORCID for Martyn Hill: ORCID iD orcid.org/0000-0001-6448-9448
ORCID for Nicholas R. Harris: ORCID iD orcid.org/0000-0003-4122-2219

Catalogue record

Date deposited: 10 Nov 2008 17:57
Last modified: 18 Feb 2021 16:42

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