Loo, Evelyn, Zhu, Yanan, Lai, Jun S., Chan, Yiong Huak, Ong, C., Tham, Elizabeth Huiwen, Goh, Anne, Teoh, Oon Hoe, Tan, Kok Hian, Yap, Fabian, Chong, Yap Seng, Gluckman, Peter D., Godfrey, Keith, Van Bever, Hugo, Lee, Bee Wah, Chong, Mary Foong-Fong and Shek, Lynette Pei-Chi (2019) Association between maternal carotenoids, vitamin A and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life. Pediatric Allergy and Immunology. (doi:10.1111/pai.13122).
Abstract
The development of allergic disease starts prenatally, a vital period during which maternal exposure such as nutrient intake may modulate fetal and infant immune programming [1]. However, the role of various nutrients intake during maternal pregnancy, for instance, carotenoids, vitamin A and vitamin E, in the development of allergic diseases in the offspring is inconclusive. In this study, we aim to investigate the relationship between these nutrient levels in maternal plasma at delivery and subsequent offspring allergic outcomes in the first 5 years of life in the prospective mother‐offspring cohort study Growing Up in Singapore Towards healthy Outcomes (GUSTO).
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