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Association between maternal carotenoids, vitamin A and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life

Association between maternal carotenoids, vitamin A and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life
Association between maternal carotenoids, vitamin A and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life
The development of allergic disease starts prenatally, a vital period during which maternal exposure such as nutrient intake may modulate fetal and infant immune programming [1]. However, the role of various nutrients intake during maternal pregnancy, for instance, carotenoids, vitamin A and vitamin E, in the development of allergic diseases in the offspring is inconclusive. In this study, we aim to investigate the relationship between these nutrient levels in maternal plasma at delivery and subsequent offspring allergic outcomes in the first 5 years of life in the prospective mother‐offspring cohort study Growing Up in Singapore Towards healthy Outcomes (GUSTO).
0905-6157
Loo, Evelyn
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Zhu, Yanan
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Lai, Jun S.
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Chan, Yiong Huak
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Ong, C.
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Tham, Elizabeth Huiwen
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Goh, Anne
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Teoh, Oon Hoe
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Tan, Kok Hian
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Yap, Fabian
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Chong, Yap Seng
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Gluckman, Peter D.
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Godfrey, Keith
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Van Bever, Hugo
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Lee, Bee Wah
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Chong, Mary Foong-Fong
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Shek, Lynette Pei-Chi
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Loo, Evelyn
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Zhu, Yanan
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Lai, Jun S.
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Chan, Yiong Huak
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Ong, C.
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Tham, Elizabeth Huiwen
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Goh, Anne
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Teoh, Oon Hoe
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Tan, Kok Hian
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Yap, Fabian
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Chong, Yap Seng
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Gluckman, Peter D.
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Godfrey, Keith
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Van Bever, Hugo
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Lee, Bee Wah
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Chong, Mary Foong-Fong
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Shek, Lynette Pei-Chi
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Loo, Evelyn, Zhu, Yanan, Lai, Jun S., Chan, Yiong Huak, Ong, C., Tham, Elizabeth Huiwen, Goh, Anne, Teoh, Oon Hoe, Tan, Kok Hian, Yap, Fabian, Chong, Yap Seng, Gluckman, Peter D., Godfrey, Keith, Van Bever, Hugo, Lee, Bee Wah, Chong, Mary Foong-Fong and Shek, Lynette Pei-Chi (2019) Association between maternal carotenoids, vitamin A and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life. Pediatric Allergy and Immunology. (doi:10.1111/pai.13122).

Record type: Letter

Abstract

The development of allergic disease starts prenatally, a vital period during which maternal exposure such as nutrient intake may modulate fetal and infant immune programming [1]. However, the role of various nutrients intake during maternal pregnancy, for instance, carotenoids, vitamin A and vitamin E, in the development of allergic diseases in the offspring is inconclusive. In this study, we aim to investigate the relationship between these nutrient levels in maternal plasma at delivery and subsequent offspring allergic outcomes in the first 5 years of life in the prospective mother‐offspring cohort study Growing Up in Singapore Towards healthy Outcomes (GUSTO).

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Revised Maternal carotenoids and allergy-manuscript_clean EL 020819 - Accepted Manuscript
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Supplementary Table and methods_ Maternal cateronoids and allergy paper 020819 - Accepted Manuscript
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More information

Accepted/In Press date: 22 August 2019
e-pub ahead of print date: 18 September 2019

Identifiers

Local EPrints ID: 434426
URI: http://eprints.soton.ac.uk/id/eprint/434426
ISSN: 0905-6157
PURE UUID: cefe0aef-5dd9-4fdb-8852-30e6b0d4ee57
ORCID for Keith Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

Catalogue record

Date deposited: 23 Sep 2019 16:30
Last modified: 22 Nov 2021 07:42

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Contributors

Author: Evelyn Loo
Author: Yanan Zhu
Author: Jun S. Lai
Author: Yiong Huak Chan
Author: C. Ong
Author: Elizabeth Huiwen Tham
Author: Anne Goh
Author: Oon Hoe Teoh
Author: Kok Hian Tan
Author: Fabian Yap
Author: Yap Seng Chong
Author: Peter D. Gluckman
Author: Keith Godfrey ORCID iD
Author: Hugo Van Bever
Author: Bee Wah Lee
Author: Mary Foong-Fong Chong
Author: Lynette Pei-Chi Shek

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