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Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences > Southampton Clinical Trials Unit
Cancer Sciences > Southampton Clinical Trials Unit" and Year is 2021

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Number of items: 81.

Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Infection control behavior at home during the COVID-19 pandemic: Observational study of a web-based behavioral intervention (Germ Defence) - Ben Ainsworth, Sascha Miller, James Denison-Day, Beth Stuart, Julia Groot, Cathy Rice, Jennifer Bostock, Xiaoyang Hu, Kate Morton, Lauren, Brittany Towler, Michael Moore, Merlin Willcox, Tim Chadborn, Natalie Gold, Richard Amlôt, Paul Little and Lucy Yardley
Type: Article | 2021

Type: Article | 2021

Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop - David Beard, Marion Campbell, Jane M. Blazeby, Andrew Carr, Charles Weijer, Brian H. Cuthbertson, Rachelle Buchbinder, Thomas Pinkney, Felicity Bishop, Jonathan Pugh, Sian Cousins, Ian Harris, L. Stefan Lohmander, Natalie S. Blencowe, Katie Gilles, Pascal Probst, Carol Brennan, Andrew Cook, Dair Farrar-Hockley, Julian Savulescu, Richard Huxtable, Amar Rangan, Irene Tracey, Peter Brocklehurst, Manuela L. Ferreira, Jon Nicholl, B.C. Reeves, F. Hamdy, Samuel Rowley, Naomi Lee and Jonathan Cook
Type: Article | 2021 | Item not available on this server.

Direct and mediated effects of treatment context on low back pain outcome: a prospective cohort study - Felicity Bishop, Miznah Al-Abbadey, Lisa Roberts, Hugh MacPherson, Beth Stuart, Dawn Carnes, Carol Fawkes, Lucy Yardley and Katherine Bradbury
Type: Article | 2021

The effect of amoxicillin in adult patients presenting to primary care with acute cough predicted to have pneumonia or a combined viral-bacterial infection - Robin Bruyndonckx, Beth Stuart, Paul Little, Niel Hens, Margareta Ieven, Christopher C. Butler, Theo J.M. Verheij, Herman Goossens and Samuel Coenen
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Stent insertion for incurable oesophageal carcinoma: what is the optimal treatment? – authors' reply - Anthony Byrne, Douglas Adamson, Catharine Porter and Christopher Hurt
Type: Letter | 2021 | Item not available on this server.

Prevalence and determinants of depression up to 5 years after colorectal cancer surgery: results from the ColoREctal Wellbeing (CREW) study - Lynn Calman, Joshua Turner, Deborah R Fenlon, Natalia Vadimovna Permyakova, Sally Wheelwright, Mubarak I Patel, Amy Din, Jane Winter, Alison Richardson, Peter W.F. Smith and Claire Foster
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

The effect of time spent in rehabilitation on activity limitation and impairment after stroke - Beth Clark, Jill Whitall, Gert Kwakkel, Jan Mehrholz, Sean Ewings and Jane Burridge
Type: Review | 2021 | Item availability restricted.

Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE) - Simon J Crabb, Sarah Danson, James W F Catto, Syed Hussain, Danna Chan, Denise Dunkley, Nichola Downs, Ellice Marwood, Laura Day, Geoff N. Saunders, Michelle Light, Amy Whitehead, Deborah Ellis, Naveed Sarwar, Deborah Enting, Alison Jane Birtle, Bernadette Johnson, Robert Huddart and Gareth Griffiths
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021

Primary care consultations for respiratory tract symptoms during the COVID-19 pandemic: a cohort study including 70,000 people in South West England - Hajira Dambha-Miller, Hilda Hounkpatin, Jeffrey Harrisskitt-Morgan, Beth Stuart, Simon Fraser and Paul Roderick
Type: Article | 2021

Type: Article | 2021

9p gain predicts outcomes in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) treated with R-GemOx +/- Atezolizumab. ARGO: a randomised phase II study - A. Davies, P. Mckay, W. Osborne, L. Stanton, O. Tansley‐hancock, M. Lawrence, K. Mercer, A. Allen, B. Pottinger, A. Zhelyazkova, F. Miall, J. Rafferty, B. Sale, F. Cucco, L. Nunn, A. Coleman, G. Griffiths, M. Q Du, C. Burton, S. Barrons and P. Johnson
Type: Meeting abstract | 2021 | Item availability restricted.

Planning and optimising a digital intervention to protect older adults’ cognitive health - Rosie Essery, Sebastien Pollet, Kirsten Smith, Fiona Mowbray, Joanna Slodkowska-Barabasz, James Denison-Day, Victoria Hayter, Katherine Bradbury, Elisabeth Grey, Max Western, Alexander MC Milton, Cheryl Hunter, Anne Ferrey, Andre M Muller, Beth Stuart, Nanette Mutrie, Simon J. Griffin, Tony Kendrick, Helen Brooker, Bernard Gudgin, Rosemary Phillips, Tom Stokes, John Niven, Paul Little and Lucy Yardley
Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Predictors of clinical deterioration in patients with suspected COVID-19 managed in a virtual hospital' setting: A cohort study - Nick A. Francis, Beth Stuart, Matthew Knight, Rama Vancheeswaran, Charles Oliver, Merlin Willcox, Andrew Barlow and Michael Moore
Type: Article | 2021 | Item not available on this server.

Self-management for chronic widespread pain including fibromyalgia: A systematic review and meta-analysis - Adam Geraghty, Emma Maund, David Newell, Miriam Santer, Hazel Everitt, Cathy J. Price, Tamar Pincus, Michael Moore, Paul Little, Rachel West and Beth Stuart
Type: Review | 2021

Comparative accuracy and cost-effectiveness of dynamic contrast-enhanced CT and positron emission tomography in the characterisation of solitary pulmonary nodules - Fiona J. Gilbert, Scott Harris, K.A. Miles, Jonathan Weir-McCall, N.R. Qureshi, R.C. Rintoul, S. Dizdarevic, L Pike, Donald Sinclair, Andrew Shah, Rosemary Eaton, Jeremy Jones, A.J. Clegg, Benedetto Vitiello, James Hill, Andrew Cook, D Tzelis, Luke Vale, Lucy Brindle, J. Madden, Kelly Cozens, LA Little, Kathrin Eichhorst, P. Moate, C. McClement, Charles Peebles, A Bannerjee, S. Han, F.W. Poon, A.M. Groves, L. Kurban, Paul Roderick, Anthony Frew, Matthew Callister, P. Crosbie, F.V. Gleeson, K Karunasaagarar, O. Kankam and Steve George
Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

CONservative TReatment of Appendicitis in Children – a randomised controlled feasibility Trial (CONTRACT) - Nigel Hall, Simon Eaton, Frances C. Sherratt, Isabel Reading, Erin Walker, Maria Chorozoglou, Lucy Beasant, Wendy Wood, Michael Stanton, Harriet Corbett, Dean Rex, Natalie J Hutchings, Elizabeth Dixon, Simon Grist, Esther M. Crawley, Bridget Young and Jane M. Blazeby
Type: Article | 2021

Conservative treatment for uncomplicated appendicitis in children: the CONTRACT feasibility study, including feasibility RCT - Nigel Hall, Frances C. Sherratt, Simon Eaton, Isabel Reading, Erin Walker, Maria Chorozoglou, Lucy Beasant, Wendy Wood, Michael Stanton, Harriet Corbett, Dean Rex, Natalie Hutchings, Elizabeth Dixon, Simon Grist, William Van't Hoff, Esther M. Crawley, Jane M. Blazeby and Bridget Young
Type: Article | 2021

Developing an intervention to optimise the outcome of cardiac surgery in people with diabetes: the OCTOPuS pilot study - Richard Holt, Katharine Barnard-Kelly, Georgios Dritsakis, Kerensa Thorne, Lauren Cohen, Elizabeth Dixon, Mayank Patel and Andrew Cook
Type: Article | 2021

Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial - Jeremy Horwood, Melanie Chalder, Benjamin Ainsworth, James Denison-Day, Frank de Vocht, Martha M.C. Elwenspoek, Pippa Craggs, Rachel Denholm, Jonathan Sterne, Cathy Rice, Sascha, Jane Miller, Beth Stuart, Paul Little, Michael Moore, Merlin Willcox, John Macleod, Martin Gullford, Katherine Morton, Lauren Towler, NA Francis, Richard Amlot and Lucy Yardley
Type: Letter | 2021

Association of type 2 diabetes remission and risk of cardiovascular disease in pre-defined subgroups - Hilda Hounkpatin, Beth Stuart, Andrew Farmer and Hajira Dambha-Miller
Type: Article | 2021

Type: Article | 2021 | Item availability restricted.

Do patient characteristics matter when calculating sample size for eczema clinical trials? - L Howells, S Gran, B Stuart, M Santer, L. Bradshaw, C Huang, N. A. Francis and K. S. Thomas
Type: Article | 2021 | Item not available on this server.

Diarrhoea Management using Over-the-counter Nutraceuticals in Daily practice (DIAMOND): a feasibility RCT on alternative therapy to reduce antibiotic use - Yanhong Jessika Hu, Xudong Zhou, Shanjuan Wang, Merlin Willcox, Colin Garner, David Brown, Taeko Becque, Beth Stuart, Zongru Han, Qin Chang, Michael Moore and Paul Little
Type: Article | 2021 | Item not available on this server.

Can routine blood tests be modelled to detect advanced liver disease in the community: model derivation and validation using UK primary and secondary care data - Theresa Hydes, Michael Moore, Beth Stuart, Miranda Kim, Fangzhong Su, Colin Newell, David Cable, Alan Hales and Nick Sheron
Type: Article | 2021

Type: Article | 2021

Technique for inguino-femoral lymph node dissection in vulvar cancer: an international survey - Sadie Esme Fleur Jones, Pedro T. Ramirez, Geetu Prakash Bhandoria, Heng-Cheng Hsu, Navya Nair, Florencia Noll, Christopher N. Hurt, Robert Howells, Kenneth Lim and Aarti Sharma
Type: Article | 2021 | Item not available on this server.

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a phase 1, open-label, dose-escalating, randomised controlled study - Saye H. Khoo, Richard Fitzgerald, Thomas Fletcher, Sean Ewings, Thomas Jaki, Rebecca Lyon, Nichola Downs, Lauren Walker, Olana Tansley-Hancock, William Greenhalf, Christie Woods, Helen Reynolds, Ellice Marwood, Pavel Mozgunov, Emily Adams, Katie Bullock, Wayne Holman, Marcin D. Bula, Jennifer L. Gibney, Geoffrey Saunders, Andrea Corkhill, Colin Hale, Kerensa Thorne, Justin Chiong, Susannah Condie, Henry Pertinez, Wendy Painter, Emma Wrixon, Lucy Johnson, Sara Yeats, Kim Mallard, Mike Radford, Keira Fines, Victoria Shaw, Andrew Owen, David G. Lalloo, Michael R. Jacobs and Gareth Griffiths
Type: Article | 2021

Type: Article | 2021

Type: Editorial | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Extended Cohort for E-health, Environment and DNA (EXCEED) COVID-19 focus - Paul H. Lee, Anna L. Guyatt and Catherine John
Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Clinical and biological effects of combined CD27 and CD20 antibody therapy in relapsed/refractory B-cell lymphoma: the Riva trial - Sean H. Lim, Heng Sheng Sow, Christopher Wignall, Katy Mercer, Josh Caddy, Cherish Boxall, Kerensa Thorne, Joshua Northey, Louise Stanton, Zoë Konn, Keira Fines, Patrick G. Medd, Adam Coleman, Lorna Nunn, Robert Lown, Pamela Mckay, Wendy Osborne, Kim Linton, Graham P. Collins, Andrew J Gentles, Matthew Rose-zerilli and Gareth Griffiths
Type: Article | 2021 | Item availability restricted.

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Prescribing of long-term antibiotics to adolescents in primary care: a retrospective cohort study - Mark Lown, Sam McKeown, Beth Stuart, Nick Francis, Miriam Santer, George Lewith, Fangzhong Su, Michael Moore and Paul Little
Type: Article | 2021

Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms - Andrew McCarthy, Joanne Gray, Priya Sastry, Linda Sharples, Luke Vale, Andrew Cook, Peter McMeekin, Carol Freeman, Pedro Catarino and Stephen Large
Type: Article | 2021 | Item not available on this server.

Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial - Richard McManus, Paul Little, Beth Stuart, Katherine Sarah Morton, James Raftery, Joanne Marie Kelly, Katherine Bradbury, Jin Zhang, Shihua Zhu, Elizabeth Murray, Carl R. May, Frances Mair, Susan Michie, Peter W.F. Smith, Rebecca Band, Emma Ogburn, Julie Allen, Cathy Rice, Jacqui Nuttall, Bryan Williams and Lucy Yardley
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Oxaliplatin/capecitabine or carboplatin/paclitaxel-based preoperative chemoradiation for resectable oesophageal adenocarcinoma (NeoSCOPE): long-term results of a randomised controlled trial - Somnath Mukherjee, Christopher Hurt, Ganesh Radhakrishna, Sarah Gwynne, Andrew Bateman, Simon Gollins, Maria A. Hawkins, Joanne Canham, Heike I. Grabsch, Stephen Falk, Ricky A Sharma, Ruby Ray, Rajarshi Roy, Catrin Cox, Nick Maynard, Lisette Nixon, David J. Henderson-Smart, Timothy Maughan, Gareth O. Griffiths and Tom D.L. Crosby
Type: Article | 2021

Supporting self-care for eczema: protocol for two randomised controlled trials of ECO (Eczema Care Online) interventions for young people and parents/carers - Ingrid Muller, Beth Stuart, Tracey Sach, Julie Hooper, Sylvia Wilczynska, Mary Steele, Kate Greenwell, Katy Sivyer, Lucy Yardley, Hywel C Williams, Joanne R Chalmers, Paul Leighton, Laura M Howells, Matthew J Ridd, Sandra Lawton, Gareth Griffiths, Jacqui Nuttall, Sinead M Langan, Amanda Roberts, Amina Ahmed, Hayden Kirk, Taeko Becque, Paul Little, Kim S Thomas and Miriam Santer
Type: Article | 2021

A risk-adjusted and anatomically stratified cohort comparison study of open surgery, endovascular techniques and medical management for juxtarenal aortic aneurysms—the UK COMPlex AneurySm Study (UK-COMPASS): a study protocol - Shantel Patel, David Ormesher, Samuel Smith, Kitty Wong, Paul Bevis, Colin Bicknell, Jonathan Boyle, John Brennan, Bruce Campbell, Andrew Cook, Alistair Crosher, Rui Duarte, Murray Flett, Carrol Gamble, Richard Jackson, Maciej Juszczak, Ian Loftus, Ian Norton, Jai Patel, Kellie Platt, Eftychia-Eirini Psarelli, Peter Rowlands, John Smyth, Theodoros Spachos, Leigh Taggart, Claire Taylor and Srinivasa Rao Vallabhaneni
Type: Article | 2021

Type: Article | 2021

Spironolactone for adult female acne (SAFA): protocol for a double-blind, placebo-controlled, phase III randomised study of spironolactone as systemic therapy for acne in adult women - Susanne Renz, Fay Chinnery, Beth Stuart, Laura Day, Ingrid Muller, Irene Soulsby, Jacqui Nuttall, Karen Thomas, Kim Suzanne Thomas, Tracey Sach, Louise Stanton, Matthew J Ridd, Nick Francis, Paul Little, Zina Eminton, Gareth Griffiths, Alison M Layton and Miriam Santer
Type: Article | 2021

Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study - Linda Sharples, Priya Sastry, Carol Freeman, Colin Bicknell, Yi-Da Chiu, Srinivasa Rao Vallabhaneni, Andrew Cook, Joanne Gray, Andrew McCarthy, P. McMeekin, Luke Vale and Stephen Large
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

The statistician will see you now… - I.M. Stratton and K.I. Thorne
Type: Letter | 2021 | Item not available on this server.

Delayed antibiotic prescribing for respiratory tract infections: Individual patient data meta-analysis - Beth Stuart, Hilda Hounkpatin, Taeko Becque, Guiqing Yao, Shihua Zhu, Pablo Alonso-Coello, Attila Altiner, Bruce Arroll, Dankmar Böhning, Jennifer Bostock, Heiner C. Bucher, Jennifer Chao, Mariam De La Poza, Nick Francis, David Gillespie, Alastair D. Hay, Timothy Kenealy, Christin Löffler, David P. McCormick, Gemma Mas-Dalmau, Laura Muñoz, Kirsty Samuel, Michael Moore and Paul Little
Type: Article | 2021 | Item not available on this server.

Measurement properties of patient reported outcome measures for eczema control: a systematic review - Beth Stuart, Laura Howells, Rachael Pattinson, J.R. Chalmers, D. Grindlay, N. Rogers, Erin Grinich, Traci Pawlitschek, Eric L. Simpson and Kim Thomas
Type: Article | 2021 | Item not available on this server.

Authors' reply to Bradley - Beth Stuart, Paul Little, Michael Moore and Nick Francis
Type: Letter | 2021 | Item not available on this server.

Topical preparations for the treatment of mild to moderate acne vulgaris: systematic review and network meta-analysis - Beth Stuart, Emma Maund, Christopher Wilcox, Kannan Sridharan, Gowri Sivaramakrishnan, Constantinos Regas, David Newell, Irene Soulsby, Kar Fat Tang, Andrew Y. Finlay, Heiner C. Bucher, Paul Little, Alison M. Layton and Miriam Santer
Type: Review | 2021

Utilising benefit-risk assessments within clinical trials—a protocol for the BRAINS project - Nikki Totton, Steven Julious, Dyfrig Hughes, Jonathan Cook, Katie Biggs, Lizzie Coates, Andrew Cook, Catherine Hewitt and Simon Day
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Estimating the COVID-19 spread through real-time population mobility patterns: Surveillance in low-and middle-income countries - Stefanos Tyrovolas, Iago Giné-Vázquez, Daniel Fernández, Yang Lin and Paul Lee
Type: Article | 2021 | Item not available on this server.

Accuracy of rapid point-of-care antibody test in patients with suspected or confirmed COVID-19 - Rama Vancheeswaran, Merlin Luke Willcox, Beth Stuart, Matthew Knight, Hala Kandil, Andrew Barlow, Mayon Haresh Patel, Jade Stockham, Aisling O'Neill, Tristan W. Clark, Tom Wilkinson, Paul Little, Nick Francis, Gareth Griffiths and Michael Moore
Type: Letter | 2021 | Item not available on this server.

Type: Article | 2021

The use of liraglutide 3.0 mg daily in the management of overweight and obesity in people with schizophrenia, schizoaffective disorder and first episode psychosis: Results of a pilot randomized, double-blind, placebo-controlled trial - Clare A. Whicher, Hermione C. Price, Peter Phiri, Shanaya Rathod, Katharine Barnard-Kelly, Ngianga ii I Kandala, Kerensa Thorne, Carolyn Asher, Robert Peveler, Joanne McCarthy and Richard Holt
Type: Article | 2021

Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial - Merlin Willcox, Catherine Simpson, Sam Wilding, Beth Stuart, Dia Soilemezi, Amy Whitehead, Alannah Morgan, Emma Wrixon, Shihua Zhu, Guiqing Yao, Fran Webley, Ruiyang Yan, Jennifer Bostock, Margaret Bell, Gareth Griffiths, Geraldine Leydon, Paul Little, Christopher Butler, Alastair D Hay and Michael Moore
Type: Article | 2021

Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer - Frances Willenbrock, Catrin M. Cox, Eileen E. Parkes, Charlotte S. Wilhelm-Benartzi, Aswin G. Abraham, Robert Owens, Ahmad Sabbagh, Christopher M. Jones, Daniel L.I. Hughes, Tim Maughan, Christopher N. Hurt, Eric E. O’Neill and Somnath Mukherjee
Type: Article | 2021

Effect of a telecare case management program for older adults who are homebound during the COVID-19 pandemic: a pilot randomized clinical trial - Arkers Kwan Ching Wong, Frances Kam Yuet Wong, Karen Kit Sum Chow, Siu Man Wong and Paul Hong Lee
Type: Article | 2021 | Item not available on this server.

Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment - Min Zhang, Jin-Li Luo, Qianqian Sun, James Harber, Alan G. Dawson, Apostolos Nakas, Sara Busacca, Annabel J. Sharkey, David Waller, Michael T. Sheaff, Cathy Richards, Peter Wells-Jordan, Aarti Gaba, Charlotte Poile, Essa Y. Baitei, Aleksandra Bzura, Joanna Dzialo, Maymun Jama, John Le Quesne, Amrita Bajaj, Luke Martinson, Jacqui A. Shaw, Catrin Pritchard, Tamihiro Kamata, Nathaniel Kuse, Lee Brannan, Pan De Philip Zhang, Hongji Yan, Gareth Griffiths, Gareth A. Wilson, Charles Swanton, Frank Dudbridge, Edward J. Hollox and Dean A. Fennell
Type: Article | 2021

Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

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