Dataset in support of the Southampton doctoral thesis 'Remote ischaemic conditioning as a novel therapy for necrotising enterocolitis'

Abstract

Description of the data: There are essentially three datasets for this thesis. The first relates to a systematic review of NEC outcomes (Chapter 2) as consists of a single Microsoft Excel file with the details of the included papers and the data extracted from them. This systematic review is published as Jones, I H. and Hall, N.J. Contemporary Outcomes for Infants with Necrotizing Enterocolitis – A Systematic Review The Journal of Pediatrics 2020 220: 86-92.e3 The second relates to the primary research using an animal model of NEC. Each datafile is a Microsoft Excel file and contains multiple data points from each animal; including the macroscopic assessment of injury, microscopic assessment, using the Chiu-Park scoring system, serum cytokine analysis, and myeloperoxidase activity. In each case, the individual animal is identified by a unique, randomly generated 3-digit code. (Chapters 5-8 and 10). The Ethical approval for the animal work is included. Publication manuscripts in press / in production. The third set is the raw count from RNAseq transciptomics analysis of the intestine of animals in protocol 1a (plus controls). The datafile is a .csv file. Publication manuscript in production.

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