Items where Division is "Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences > Innate Immunology
Clinical and Experimental Sciences > Innate Immunology" and Year is 2021
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Number of items: 41.
Article
Type: Article
| 2021
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection - Cornelia Blume, Claire L. Jackson, Cosma Mirella Spalluto, Jelmer Legebeke, Liliya Nazlamova, Franco Conforti, Jeanne Marie Perotin, Martin Frank, John Butler, Max Crispin, Janice Coles, James Thompson, Robert A. Ridley, Lareb S.N. Dean, Matthew Loxham, Stephanie Reikine, Adnan Azim, Kamran Tariq, David A. Johnston, Paul J. Skipp, Ratko Djukanovic, Diana Baralle, Christopher J. McCormick, Donna E. Davies, Jane S. Lucas, Gabrielle Wheway and Vito Mennella
Type: Article
| 2021
Machine learning applied to atopic dermatitis transcriptome reveals distinct therapy‐dependent modification of the keratinocyte immunophenotype - Kalum Clayton, Andres Vallejo Pulido, Sofia Sirvent Bernal, James David Davies, Gemma Douilhet, Isabel Reading, Fei Ling Lim, Michael Ardern-Jones and Marta Polak
Type: Article
| 2021
An IRF1-IRF4 toggle-switch controls tolerogenic and immunogenic transcriptional programming in human Langerhans cells - James Davies, Andres F. Vallejo, Sofia Sirvent, Gemma Porter, Kalum Clayton, Yamkela Qumbelo, Patrick Stumpf, Jonathan West, Clive Gray, Nyaradzo Chigorimbo-Murefu, Benjamin Macarthur and Marta Polak
Type: Article
| 2021
Human intestinal macrophages are involved in the pathology of both ulcerative colitis and Crohn disease - Suranga Dharmasiri, Eva M. Garrido-Martin, Richard, James Harris, Adrian C. Bateman, Jane E. Collins, J.R. Fraser Cummings and Tilman Sanchez-Elsner
Type: Article
| 2021
A Personal respirator to improve protection for healthcare workers treating COVID-19 (PeRSo) - Paul Elkington, Alexander Dickinson, Mark Mavrogordato, Daniel Spencer, Richard Gillams, Antonio De Grazia, Sebastian Rosini, Diana Garay Baquero, Laura Diment, Nitin Mahobia, Alexandra Mant, Tom Baynham and Hywel Morgan
Type: Article
| 2021
Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy - Simon Eschweiler, James Clarke, Ciro Ramírez-suástegui, Bharat Panwar, Ariel Madrigal, Serena J. Chee, Ioannis Karydis, Edwin Woo, Aiman Alzetani, Somaia Elsheikh, C. J. Hanley, G. J. Thomas, Peter S. Friedmann, Tilman Sanchez-elsner, Ferhat Ay, Christian H. Ottensmeier and Pandurangan Vijayanand
Type: Article
| 2021
Selinexor enhances NK cell activation against malignant B cells via downregulation of HLA-E - Jack, Graham Fisher, Salim Khakoo, Mark Cragg, Francesco Forconi, Peter Johnson, Amber Doyle, christopher Walker, yosef landesman and Matthew Blunt
Type: Article
| 2021
Real-world omalizumab and mepolizumab treated difficult asthma phenotypes and their clinical outcomes - Wei Chern Gavin Fong, Adnan Azim, Deborah Knight, Heena Mistry, Anna Freeman, Mae Felongco, Aref Kyyaly, Matthew Harvey, Patrick Dennison, Hongmei Zhang, Peter Howarth, S Hasan Arshad, Ramesh J Kurukulaaratchy and Mohammed Aref Kyyaly
Type: Article
| 2021
Inductively coupled plasma mass spectrometry method for plasma and intracellular antimony quantification applied to pharmacokinetics of meglumine antimoniate - Diana J. Garay-Baquero, David E. Rebellón-Sánchez, Miguel D. Prieto, Lina Giraldo-Parra, Adriana Navas, Sheryl Atkinson, Stuart McDougall and Maria Adelaida Gómez
Type: Article
| 2021
Dual Dean entrainment with volume ratio modulation for efficient droplet co-encapsulation: extreme single-cell indexing - Jack Harrington, Luis Blay Esteban, Jonathan Butement, Andres F. Vallejo, Simon I.R. Lane, Bhavwanti Sheth, Maaike S.A. Jongen, Rachel Parker, Patrick S. Stumpf, Rosanna C.G. Smith, Ben D. MacArthur, Matthew J.J. Rose-Zerilli, Marta E. Polak, Tim Underwood and Jonathan West
Type: Article
| 2021
A peptide: MHC based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors. - Salim Khakoo, Pauline E Rettman, Matthew Blunt, Rebecca Fulton, Andres Vallejo Pulido, Leidy Bastidas Legarda, Laura Espana-Serrano, Marta Polak, Aymen Al-Shamkhani and Christelle Retiere
Type: Article
| 2021
Epigenome-scale comparison of DNA methylation between blood leukocytes and bronchial epithelial cells - Yu-Sheng Lee, Hongmei Zhang, Yu Jiang, Latha Perunthadambil Kadalayil, Wilfried Karmaus, Susan L. Ewart, Syed Arshad and John Holloway
Type: Article
| 2021
Doxycycline host-directed therapy in human pulmonary tuberculosis - Quig Miow, Andres Vallejo Pulido, Yu Wang, Jia Hong, Chen Bai, Felicia Teo, Alvin Wang, Hong Loh, Tuan Tan, Ying Ding, Hoi She, Suay Gan, Nicholas Paton, Josephine Lum, Alicia Tay, Cynthia Chee, Paul Tambyah, Marta Polak, Yee Wang, Amit Singhal, Paul Elkington, Jon S. Friedland and Catherine W.M. Ong
Type: Article
| 2021
| Item availability restricted.
The clinical implications of Aspergillus Fumigatus sensitization in difficult-to-treat asthma patients - Heena Mistry, Hilda Maria Ajsivinac Soberanis, Mohammad Aref Kyyaly, Adnan Azim, Clair Barber, Deborah Knight, Colin Newell, Hans Michael Haitchi, Tom Wilkinson, Peter Howarth, Grégory Seumois, Pandurangan Vijayanand, S Hasan Arshad and Ramesh J Kurukulaaratchy
Type: Article
| 2021
Infections due to Dysregulated Immunity: An emerging complication of Cancer Immunotherapy - Tommaso Morelli, Kohei Fujita, Gil Redelman-Sidi and Paul Elkington
Type: Article
| 2021
Powered respirators are effective, sustainable, and cost-effective personal protective equipment for SARS-CoV-2 - Alasdair Munro, Jacqui Prieto, Emmanouil Mentzakis, Mohammed AM Mansour, Nitin Mahobia, Peter Baker, Sarah Herbert, Trevor Smith, Matthew Hine, Joann Hall, Angie McClarren, Mike Davidson, Julie Brooks, Jane Fisher, David Griffiths, Hywel Morgan, Corrado Giulietti, Saul Faust and Paul Elkington
Type: Article
| 2021
Tissue-resident-like CD4
+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung - Paul Ogongo, Liku Bekele Tezera, Amanda Ardain, Shepherd Nhamoyebonde, Duran Ramsuran, Alveera Singh, Abigail Ng'oepe, Farina Karim, Taryn Naidoo, Khadija Khan, Kaylesh Dullabh, Michael Fehlings, Boon Heng Lee, Alessandra Nardin, Cecilia Lindestam Arlehamn, Alessandro Sette, Samuel Behar, Adrie Steyn, Rayhmun Madansein, Henrik Kløverpris, Paul Elkington and Alasdair Leslie
Type: Article
| 2021
| Item availability restricted.
BMI trajectory in childhood is associated with asthma incidence at young adulthood mediated by DNA Methylation - Rutu Rathod, Hongmei Zhang, Wilfried Karmaus, Susan Ewart, Latha Perunthadambil Kadalayil, Caroline L. Relton, Susan Ring, Syed Arshad and John Holloway
Type: Article
| 2021
Specialist respiratory outreach: a case-finding initiative for identifying undiagnosed COPD in primary care - Emma Ray, David Culliford, Helen Kruk, Kate Gillett, Mal North, Carla M. Astles, Alexander Hicks, Matthew Johnson, Sharon Xiaowen Lin, Rosanna Orlando, Mike Thomas, Rachel E. Jordan, David Price, Mita Konstantin and Tom M. A. Wilkinson
Type: Article
| 2021
| Item not available on this server.
Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets - Michaela T. Reichmann, Liku Bekele Tezera, Andres Vallejo Pulido, Milica Vukmirovic, Rui Xiao, James Reynolds, Sanjay Jogai, Susan Wilson, Benjamin Marshall, Mark Jones, Alasdair Leslie, Jeanine M. D'Armiento, Naftali Kaminski, Marta Polak and Paul Elkington
Type: Article
| 2021
3D cyclorama for digital unrolling and visualisation of deformed tubes - Harry Rossides, Sylvia Pender and Philipp Schneider
Type: Article
| 2021
Phase-contrast imaging in practice: protocol design flowchart for X-ray propagation-based phase-contrast imaging - Harry Rossides, Sylvia Pender and Philipp Schneider
Type: Article
| 2021
| Item not available on this server.
Sex-specific longitudinal association of DNA methylation with lung function - Shadia Khan Sunny, Hongmei Zhang, Caroline L. Relton, Susan Ring, Latha Perunthadambil Kadalayil, Fawaz Mzayek, Susan Ewart, John W. Holloway and Syed Arshad
Type: Article
| 2021
| Item not available on this server.
Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering - Andres F. Vallejo, James Davies, Amit Grover, Ching-hsuan Tsai, Robert Jepras, Marta E. Polak and Jonathan West
Type: Article
| 2021
A multiancestry sex-stratified genome-wide association study of spontaneous clearance of hepatitis C virus - Candelaria Vergara, Ana Valencia, Chloe L. Thio, James J. Goedert, Alessandra Mangia, Valeria Piazzolla, Eric Johnson, Alex H. Kral, Thomas R. O'Brien, Shruti H. Mehta, Gregory D. Kirk, Arthur Y. Kim, Georg M. Lauer, Raymond T. Chung, Andrea L. Cox, Marion G. Peters, Salim I. Khakoo, Laurent Alric, Matthew E. Cramp, Sharyne M. Donfield, Brian R. Edlin, Michael P. Busch, Graeme Alexander, Hugo R. Rosen, Edward L. Murphy, Genevieve L. Wojcik, Margaret A. Taub, David L. Thomas and Priya Duggal
Type: Article
| 2021
| Item not available on this server.
The role of NK cells in oncolytic viral therapy: a focus on hepatocellular carcinoma - Frazer Warricker, Salim I. Khakoo and Matthew D. Blunt
Type: Article
| 2021
Book Section
In vitro models of human granuloma formation to analyze host-directed therapies - MICHAELA REICHMANN, Paul Elkington and Liku Bekele Tezera
Type: Book Section
| 2021
| Springer Nature
| Item not available on this server.
Conference or Workshop Item
Integration of a hybrid photon counting detector into a lab-based μCT scanner for 3D X-ray histology - Philip J Basford, Orestis L. Katsamenis, Richard Boardman, Stephanie Robinson, Elena Konstantinopoulou, Spyridon Gkoumas, Thomas Thuering, Peter Lackie, Simon Cox and Philipp Schneider
Type: Conference or Workshop Item
| 2021
Tools for shared annotation of correlative 2D light microscopy and 3D X-ray histology - Elaine, Ming Li Ho, Janina Wolf, Matthew Lawson, T. E. Trandafir, Elena Konstantinopoulou, Orestis L. Katsamenis, Andrew Stubbs, Peter Lackie, Jan von der Thüsen and Philipp Schneider
Type: Conference or Workshop Item
| 2021
| Item availability restricted.
Combining micro-CT imaging with traditional histology in a correlative imaging approach to investigate tuberculosis pathology in the human lung - Elena Konstantinopoulou, Orestis L. Katsamenis, Sanjay Jogai, David Chatelet, Matthew Lawson, Philip J Basford, Elaine, Ming Li Ho, Philipp Schneider and Paul Elkington
Type: Conference or Workshop Item
| 2021
Investigating tuberculosis pathology in the human lung with 3D X-ray Histology; a correlative imaging approach - Elena Konstantinopoulou, Orestis L. Katsamenis, Sanjay Jogai, David Chatelet, Matthew Lawson, Philip J Basford, Elaine, Ming Li Ho, Philipp Schneider and Paul Elkington
Type: Conference or Workshop Item
| 2021
Differential toxicity in an alveolar epithelial cell line of fine particulate matter from brakewear, roadwear, and diesel exhaust - James Parkin, Lareb Dean, Joseph Bell, Yihua Wang, Matthew Cooper, Natasha Hazel Celeste Easton, Robert Ridley, Franco Conforti, Helen Vethakan Raj, Julian Downward, Yihua Wang, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Richard Cook, Mark Jones, Donna Davies and Matthew Loxham
Type: Conference or Workshop Item
| 2021
| Item not available on this server.
Dataset
Type: Dataset
| 2021
| University of Southampton
Type: Dataset
| 2021
| University of Southampton
Type: Dataset
| 2021
| University of Southampton
| Item not available on this server.
Type: Dataset
| 2021
| NCBI (National Center for Biotechnology Information) GEO (Gene Expression Omnibus)
| Item not available on this server.
Type: Dataset
| 2021
| University of Southampton
Type: Dataset
| 2021
| University of Southampton
Letter
Circulating miRNAs – a potential tool to identify severe asthma risk? - Mohammed Aref Kyyaly, Tilman Sanchez-Elsner, Peijun He, Collin L. Sones, S Hasan Arshad and Ramesh J. Kurukulaaratchy
Type: Letter
| 2021
Review
Understanding the Tuberculosis granuloma: the Matrix revolutions - Paul Elkington, Marta Polak, MT Reichmann and Alasdair Leslie
Type: Review
| 2021