Items where Division is "Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences > Allergy, Immunity and Respiratory
Clinical and Experimental Sciences > Allergy, Immunity and Respiratory" and Year is 2022
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Number of items: 133.
27 mast cells in the urinary bladders of interstitial cystitis/bladder pain syndrome patients express the mast cell related G-protein coupled receptor X2 (MRGPRX2): potential role in the pathogenesis of neurogenic inflammation - O. Abdelwahab, H. Markham, M. Yusuh, D. Johnston, S. Harris, P. Sirikhansaeng, K. Garba, B. Birch and B. Lwaleed
Type: Meeting abstract
| 2022
Nontypeable Haemophilus influenzae infection of pulmonary macrophages drives neutrophilic inflammation in severe asthma - Jodie Ackland, Clair Barber, Ashley Heinson and Adnan Azim
Type: Article
| 2022
NTHi-IAV coinfection of macrophages alters infection outcomes and inflammatory responses - Jodie Ackland, Ashley Heinson, David Cleary, Myron Christodoulides, Tom M.A. Wilkinson and Karl Staples
Type: Meeting abstract
| 2022
| Item not available on this server.
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial - Saul N. Faust
Type: Article
| 2022
IL-33 induces an antiviral signature in mast cells but enhances their permissiveness for human rhinovirus infection - Charlene Akua Dufie Akoto, Anna Willis, Chiara Francesca Banas, Joseph A. Bell, Dean Bryant, Cornelia Blume, Donna E. Davies and Emily J. Swindle
Type: Article
| 2022
Predicting Pulmonary Function From the Analysis of Voice: A Machine Learning Approach - Md. Zahangir Alam, Albino Simonetti, Raffaele Brillantino, Nick Tayler, Chris Grainge, Pandula Siribaddana, S. A. Reza Nouraei, James Batchelor, M. Sohel Rahman, Eliane V. Mancuzo, John W. Holloway, Judith A. Holloway and Faisal I. Rezwan
Type: Article
| 2022
Clinical benefit of baricitinib treatment for moderate-to-severe atopic dermatitis in combination with topical corticosteroids: a post hoc analysis of the BREEZE-AD7 and BREEZE-AD4 phase III trials - Mahreen Ameen, Michael Ardern-Jones, Hamish Hunter, Susanne Grond, Fan Emily Yang, Yun-Fei Chen, Robert McKenzie and Alan Irvine
Type: Meeting abstract
| 2022
Non-typeable Haemophilus influenzae-Moraxella catarrhalis vaccine for the prevention of exacerbations in chronic obstructive pulmonary disease: a multicentre, randomised, placebo-controlled, observer-blinded, proof-of-concept, phase 2b trial - Stefan Andreas, Marco Testa and Laurent Boyer
Type: Article
| 2022
| Item availability restricted.
Long-term efficacy and safety of abrocitinib in patients with moderate-to-severe atopic dermatitis who had failed or were intolerant to oral nonsteroidal immunosuppressants: pooled analysis of JADE clinical trials - M. Ardern-Jones, M. Ameen, M. de Bruin-Weller, E. Simpson, W. S. Chiu, P. Biswas, G. Chan, C. Koulias and S. Weidinger
Type: Meeting abstract
| 2022
| Item not available on this server.
Efficacy of abrocitinib vs. dupilumab in adults with moderate-to-severe atopic dermatitis who had an inadequate response or intolerance to nonsteroidal immunosuppressants: results from JADE DARE - Michael Ardern-Jones, Mahreen Ameen, Marjolein de Bruin-Weller, Eric Simpson, Wing Sin Chiu, Fan Zhang, Gary Chan, Christopher Koulias and Stephan Weidinger
Type: Meeting abstract
| 2022
Using machine learning to impact on long-term clinical care: principles, challenges, and practicalities - James J. Ashton, Aneurin Young, Mark J. Johnson and R. Mark Beattie
Type: Review
| 2022
Measurement of exhaled volatile organic compounds as a biomarker for personalised medicine: assessment of short-term repeatability in severe asthma - Adnan Azim, Faisal I. Rezwan, Clair Barber, Matthew Harvey, Ramesh J. Kurukulaaratchy, John W. Holloway and Peter H. Howarth
Type: Article
| 2022
Validation and further insight into the International Severe Asthma Registry (ISAR) eosinophil gradient algorithm in the Wessex AsThma CoHort of difficult asthma (WATCH) using historical blood eosinophil counts and induced sputum - Clair Barber, Adnan Azim, Colin Newell, Aref Kyyaly, Hitasha Rupani, Hans Michael Haitchi, Peter Howarth and Ramesh Kurukulaaratchy
Type: Letter
| 2022
An international survey on nasal nitric oxide measurement practices for the diagnosis of primary ciliary dyskinesia - Nicole Beydon, T. Ferkol, Amanda Harris, M Colas, Stephanie D. Davis, Eric G. Haarman, Claire Hogg, Emma Kilbride, Panayiotis Kouis, Claudia E. Kuehni, Philipp Latzin, Diana Marangu, June K. Marthin, Kim G. Nielsen, Phil Robinson, Nisreen Rumman, Matthew Rutter, Woolf Walker and Jane Lucas
Type: Article
| 2022
Letter to the Editor on “Feasibility of nasal NO screening in healthy newborns” - Nicole Beydon and Jane Lucas
Type: Letter
| 2022
| Item availability restricted.
Sarcopenia and myosteatosis predict adverse outcomes after emergency laparotomy: a multi-centre observational cohort study - Samantha Body, Marjolein A. P. Ligthart, Saqib Rahman, James Ward, Peter May-miller, Philip H. Pucher, Nathan J. Curtis, Malcolm A. West, Clizia Airofarulla, Louise Alder, Nicholas Baylem, David Berry, Anastasia Benjafield, Thakshyanee Bhuvanakrishna, Amanda Bond, Richard Booth, Jack Broadhurst, James P. Byrne, Rachel Carten, Duncan Chambler, Heather Davis, Mark R. Edwards, Paul Froggatt, Nader Francis, Michael P. W. Grocott, Gui Han Lee, Denny Z. H. Levett, Camilla Hickish, Frances Howse, Prashan Kangesu, Zeeshan Khawaja, Jieyun Lee, Chui Lee, Jenny Mclachlan, Stuart Mercer, Alex H. Mirnezami, Brendan Moran, Victoria Morrison Jones, Kate Nicholls, Steven W. M. Olde Damink, Katherine Pearson, John N. Primrose, Paul Robinson, Eva Sorensen, Benjamin M. Stubbs, Noori Suhail, Simon Toh, Michael Terry, Alexios Tzivanakis and Timothy J. Underwood
Type: Article
| 2022
Core Outcome Measures for Perioperative and Anaesthetic Care (COMPAC): a modified Delphi process to develop a core outcome set for trials in perioperative care and anaesthesia - Oliver Boney, S. Ramani Moonesinghe, Paul S. Myles, Michael P.W. Grocott, J. Bartoszko and W. S. Beattie
Type: Article
| 2022
| Item not available on this server.
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis - Christopher J. Brereton, Liudi Yao and Elizabeth R. Davies
Type: Article
| 2022
| Item availability restricted.
Pulmonary EV miRNA profiles identify disease and distinct inflammatory endotypes in COPD - Hannah Burke, Doriana Cellura, Anna Freeman, Alexander P Hicks, Kristoffer Ostridge, Alastair Watson, Nicholas Paul Williams, Cosma Mirella Spalluto, Karl J. Staples and Thomas Wilkinson
Type: Article
| 2022
Biomarker identification using dynamic time warping analysis: a longitudinal cohort study of patients with COVID-19 in a UK tertiary hospital - Hannah Burke, Anna Freeman, Paul O'Regan, Oskar Wysocki, Andre Freitas, Ahilanandan Dushianthan, Michael Celinski, James Batchelor, Hang Phan, Florina Borca, Natasha Sheard, Sarah Williams, Alastair Watson, Paul Fitzpatrick, Dónal Landers and Tom Wilkinson
Type: Article
| 2022
Plasma and airway levels of surfactant protein D degradation reflect progression of ARDS in entilated patients with SARS-CoV-2 - T. Castillo, J. Madsen, A. Postle, D. Brealey, J.B. Fink, M. Grocott, A. Dushianthan and H.W. Clark
Type: Meeting abstract
| 2022
| Item not available on this server.
Immunocompromised children and young people are at no increased risk of severe COVID-19 - H. Chappell, R. Patel, C. Driessens, A.W. Tarr, W.l. Irving, P.J. Tighe, H.J. Jackson, T. Harvey-cowlishaw, L. Mills, M. Shaunak, D. Gbesemete, A. Leahy, J.S. Lucas, S.N. Faust and H. De Graaf
Type: Article
| 2022
Prediction of chronic obstructive pulmonary disease exacerbation events by using patient self-reported data in a digital health app: statistical evaluation and machine learning approach - Francis P Chmiel, Dan Burns, John Brian Pickering, Alison Blythin, Thomas MA Wilkinson and Michael J Boniface
Type: Article
| 2022
I-COPTIC: Implementation of community pharmacy-based testing for hepatitis C: Delphi consensus protocol - Charlotte Cook, Leila Reid and Stuart Smith
Type: Article
| 2022
| Item not available on this server.
Anti-viral responses of tissue-resident CD49a+ lung NK cells are dysregulated in COPD - Grace Elizabeth Cooper, Jemma Mayall, Chantal Donovan, Tatt J. Haw, Kurtis F. Budden, Nicole G. Hansbro, Evy E. Blomme, Tania Maes, Chia Wei Kong, Jay C. Horvat, Salim I. Khakoo, Tom MA Wilkinson, Philip M. Hansbro and Karl J. Staples
Type: Article
| 2022
Oxygen targets during mechanical ventilation in the ICU: a systematic review and meta-analysis - Andrew F. Cumpstey, Alex H. Oldman, Daniel S. Martin, Andrew Smith and Michael P.W. Grocott
Type: Review
| 2022
Improving physical function of patients following intensive care unit admission (EMPRESS): protocol of a randomised controlled feasibility trial - Rebecca Cusack, Andrew Bates, Kay Mitchell, Zoe van Willigen, Linda Denehy, Nicholas Hart, Ahilanandan Dushianthan, Isabel Reading, Maria Chorozoglou, Gordon Sturmey, Iain Davey and Michael Grocott
Type: Article
| 2022
Nurse staffing levels and patient outcomes: a systematic review of longitudinal studies - Chiara Dall'ora, Christina Saville, Bruna Rubbo, Lesley Turner, Jeremy Jones and Peter Griffiths
Type: Review
| 2022
Transcriptional programming of immunoregulatory responses in human Langerhans cells - James Davies, Sofia Sirvent, Andres F. Vallejo, Kalum Clayton, Gemma Douilhet, Patrick S. Keeler, Jonathan West, Michael Ardern-Jones, Ben D. MacArthur, Harinder Singh and Marta E. Polak
Type: Article
| 2022
From theory to practice: an international approach to establishing prehabilitation programmes - June F. Davis, Stefan J. Van Rooijen, Chloe Grimmett, Malcom A. West, Anna M. Campbell, Rashami Awasthi, Gerrit D. Slooter, Michael P. Grocott, Franco Carli and Sandy Jack
Type: Article
| 2022
Biallelic variants in CEP164 cause a motile ciliopathy-like syndrome - Laura A. Devlin, Janice Coles, Claire L. Jackson, Miguel Barroso-Gil, Ben Green, Woolf T. Walker, N. Simon Thomas, James Thompson, Simon A. Rock, Ruxandra Neatu, Laura Powell, Elisa Molinari, Ian Wilson, Heather J. Cordell, Eric Olinger, Colin Miles, John Sayer, Gabrielle Wheway and Jane Lucas
Type: Article
| 2022
The impact on parents of diagnosing PCD in young children - Corine Driessens, Siobhan Carr, Edel Clough, Fiona Copeland, Sharon Dell, Lucy Dixon, Amanda Harris, Rebecca Knibb, Margaret Leigh, Manjith Narayanan, Beatrice Redfern, Evie Robson, Michael Sawras, Lynne Schofield, Kelly Sullivan, Myra Tipping, Nhu Tran, Woolf Walker, Jane Lucas and Laura Behan
Type: Article
| 2022
The effect of the COVID-19 pandemic on severe asthma care in Europe: will care change for good? - Katrien Eger, Dora Paroczai, Alison Bacon, Florence Schleich, Svetlana Sergejeva, Arnaud Bourdin, Isabelle Vachier, Eleftherios Zervas, Konstantinos Katsoulis, Dimosthenis Papapetrou, Konstantinos Kostikas, Zsuzsanna Csoma, Enrico Heffler, Giorgio Walter Canonica, Ineta Grisle, Kristina Bieksiene, Jolita Palacionyte, Anneke Ten Brinke, Simone Hashimoto, Frank W.j.m. Smeenk, Gert-jan Braunstahl, Simone Van Der Sar, Florin Mihălţan, Natalia Nenasheva, Marina Peredelskaya, Biljana Zvezdin, Ivan Čekerevac, Sanja Hromiš, Vojislav Ćupurdija, Zorica Lazic, Branislava Milenkovic, Sanja Dimic-janjic, Valentyna Yasinska, Barbro Dahlén, Apostolos Bossios, Nikolaos Lazarinis, David Aronsson, Arne Egesten, Abul Kashem Mohammad Munir, Lars Ahlbeck, Christer Janson, Sabina Škrgat, Natalija Edelbaher, Joerg Leuppi, Fabienne Jaun, Jochen Rüdiger, Nikolay Pavlov, Pietro Gianella, Reta Fischer, Florian Charbonnier, Rekha Chaudhuri, Steven James Smith, Simon Doe, Michelle Fawdon, Matthew Masoli, Liam Heaney, Hans Michael Haitchi, Ramesh Kurukulaaratchy, Olivia Fulton, Betty Frankemölle, Toni Gibson, Karen Needham, Peter Howarth, Ratko Djukanovic, Elisabeth Bel and Michael Hyland
Type: Article
| 2022
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study - Rachel Evans, Olivia C Leavy, Matthew Richardson, Omer Elneima, Hamish J C McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth Saunders, Nick Hart, John R Hurst, Betty Raman, Ewen Harrison, Louise V Wain, Christopher Brightling and Philip Calder
Type: Article
| 2022
Spatially resolved deconvolution of the fibrotic niche in lung fibrosis - Michael Eyres, Joseph A. Bell and Elizabeth R. Davies
Type: Article
| 2022
Systems redox biology in health and disease - Martin Feelisch, Miriam M. Cortese-Krott, Jerome Santolini, Stephen Wootton and Alan Jackson
Type: Review
| 2022
Type: Dataset
| 2022
| University of Southampton
Real-time monitoring of epithelial barrier function by impedance spectroscopy in a microfluidic platform - Joao, Cabaco Fernandes, Nikita Karra, Joel Bowring, Riccardo Reale, Jonathan James, Theresa Pell, Cornelia Blume, Wendy Rowan, Donna Davies, Emily Swindle and Hywel Morgan
Type: Article
| 2022
Type: Dataset
| 2022
| University of Southampton
Type: Dataset
| 2022
| University of Southampton
Wave comparisons of clinical characteristics and outcomes of COVID-19 admissions - Exploring the impact of treatment and strain dynamics - Anna Freeman, Alastair Watson, Paul O'Regan, Oskar Wysocki, Hannah Burke, Andre Freitas, Robert Livingstone, Ahilanadan Dushianthan, Michael Celinski, James Batchelor, Hang Phan, Florina Borca, Paul Fitzpatrick, Donal Landers and Tom MA Wilkinson
Type: Article
| 2022
Heterogeneity in the use of biologics for severe asthma in Europe: a SHARP ERS study - Anne-Noelle Frix, Liam G. Heaney, Barbro Dahlén, Florin Mihaltan, Svetlana Sergejeva, Sanja Popović-Grle, Vratislav Sedlak, Lauri Lehtimäki, Arnaud Bourdin, Stephanie Korn, Eleftherios Zervas, Zsuzsanna Csoma, Dora Lúðvíksdóttir, Marcus Butler, Giorgio Walter Canonica, Ineta Grisle, Kristina Bieksiene, Anneke Ten Brinke, Piotr Kuna, Claudia Chaves Loureiro, Natalia M Nenasheva, Zorica Lazic, Sabina Škrgat, David Ramos-Barbon, Joerg Leuppi, Bilun Gemicioglu, Apostolos Bossios, Celeste M Porsbjerg, Elisabeth H. Bel, Ratko Djukanovic and Renaud Louis
Type: Article
| 2022
Iron deposition in the brain after aneurysmal subarachnoid haemorrhage - Ian Galea, Andrew Durnford, James Glazier, Sophie Mitchell, Suraj Kohli, Lesley Foulkes, Jeanette Norman, Angela Darekar, Seth Love, Diederik Bulters, James Nicoll and Delphine Boche
Type: Article
| 2022
Type: Dataset
| 2022
| University of Southampton
Microfluidic technologies for ex vivo tissue biopsies: a review - Fernando, Carlos Garcia Garcia, Pelin Candarlioglu, James Porter, Emily Swindle, Donna Davies and Hywel Morgan
Type: Review
| 2022
Efficacy and safety of abrocitinib in biologic-exposed versus biologic-naive patients with moderate-to-severe atopic dermatitis - M. Gooderham, B. Strober, M. Ardern-Jones, E. Guttman-Yassky, M. Levenberg, G. Chan, P. Biswas and M. Watkins
Type: Meeting abstract
| 2022
British Society for Allergy and Immunology (BSACI) Abstracts of the World Allergy Organization (WAO) & BSACI 2022 UK Conference 25th-27th April 2022, Edinburgh International Conference Centre (EICC) - Raquel Granell, Sadia Haider, Matea Deliu, Anhar Ullah, Osama Mahmoud, Sara Fontanella, Angela Simpson, Steve Turner, Syed Hasan Arshad, Clare Murray, Graham Roberts, John Holloway and Adnan Custovic
Type: Meeting abstract
| 2022
| Item not available on this server.
“Eczema shouldn’t control you; you should control eczema”: qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema - Kate Greenwell, Katy Sivyer, Laura Howells, Mary Steele, Matthew J. Ridd, Amanda Roberts, Amina Ahmed, Sandra Lawton, Sinéad M. Langan, Julie Hooper, Sylvia Wilczynska, Paul Leighton, Gareth Griffiths, Tracey Sach, Paul Little, Hywel C. Williams, Kim S. Thomas, Lucy Yardley, Miriam Santer and Ingrid Muller
Type: Article
| 2022
| Item not available on this server.
Delineating associations of progressive pleuroparenchymal fibroelastosis in patients with pulmonary fibrosis - Eyjolfur Gudmundsson, An Zhao, Nesrin Mogulkoc, Athol Wells, Mark Jones, Coline van Moorsel, Joanna Porter, Wim Wuyts, Iain Stewart and Joseph Jacob
Type: Article
| 2022
| Item availability restricted.
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction - Scott E Guimond, Courtney J Mycroft-West, Neha S Gandhi, Julia A Tree, Thuy T Le, C Mirella Spalluto, Maria V Humbert, Karen R Buttigieg, Naomi Coombes, Michael J Elmore, Matthew Wand, Kristina Nyström, Joanna Said, Yin Xiang Setoh, Alberto A Amarilla, Naphak Modhiran, Julian D J Sng, Mohit Chhabra, Paul R Young, Daniel J Rawle, Marcelo A Lima, Edwin A Yates, Richard Karlsson, Rebecca L Miller, Yen-Hsi Chen, Ieva Bagdonaite, Zhang Yang, James Stewart, Dung Nguyen, Stephen Laidlaw, Edward Hammond, Keith Dredge, Tom M A Wilkinson, Daniel Watterson, Alexander A Khromykh, Andreas Suhrbier, Miles W Carroll, Edward Trybala, Tomas Bergström, Vito Ferro, Mark A Skidmore and Jeremy E Turnbull
Type: Article
| 2022
Efficacy and safety of a recombinant plant-based adjuvanted Covid-19 vaccine - Karen J Hager, Gonzalo Pérez Marc, Philipe Gobeil, Ricardo S Diaz, Gretchen Heizer and Conrado Llapur
Type: Article
| 2022
Evolution of eczema, wheeze and rhinitis from infancy to early adulthood: four birth cohort studies - Sadia Haider, Sara Fontanella, Anhar Ullah, Stephen Turner, Angela Simpson, Graham Roberts, Clare S. Murray, John W. Holloway, John A. Curtin, Paul Cullinan, Syed Hasan Arshad, Guillem Hurault, Raquel Granell and Adnan Custovic
Type: Article
| 2022
Multimorbidity in difficult asthma: the need for personalised and non-pharmacological approaches to address a difficult breathing syndrome - Hans Michael Haitchi, Judit Varkonyi-Sepp, Anna Freeman and Ben Ainsworth
Type: Article
| 2022
Lung function from school age to adulthood in primary ciliary dyskinesia - Florian S. Halbeisen, Eva S.L. Pedersen, Myrofora Goutaki, Ben Spycher, Israel Amirav, Mieke Boon, M Cohen-Cymberknoh, Suzanne Crowley, Nagehan Emiralioglu, Eric G. Haarman, Bulent Karadag, Cordula Koerner-Rettberg, Philipp Latzin, Michael R. Loebinger, Jane Lucas, Henryk Mazurek, Lucy Morgan, June K. Marthin, Petr Pohunek, Francesca Santamaria, Nicolaus Schwerk, Guillaume Thouvenin, Panayiotis Yiallouros, Kim G. Nielsen and Claudia E. Kuehni
Type: Article
| 2022
A capaciflector provides continuous and accurate respiratory rate monitoring for patients at rest and during exercise - Nick Hayward, Mahdi Shaban, James Badger, Isobel Jones, Yang Wei, Daniel Spencer, Stefania Isichei, Martin Knight, James Otto, Gurinder Rayat, Denny Levett, Michael Grocott, Harry Akerman and Neil White
Type: Article
| 2022
Dietary nitrate supplementation does not alter exercise efficiency at high altitude - further results from the Xtreme Alps Study - Philip J. Hennis, Andrew F. Cumpstey, Alasdair F O'Doherty and Monty G Mythen
Type: Article
| 2022
Incidence and 1-year outcome of periprocedural myocardial infarction following cardiac surgery: are the Universal Definition and Society for Cardiovascular Angiography and Intervention criteria fit for purpose? - Jonathan Hinton, Maclyn Augustine, Lavinia Gabara, Mark Mariathas, Rick Allan, Florina Borca, Zoe Nicholas, John Ikwoube, Neil Gillett, Chun Shing Kwok, Paul Cook, Michael P.W. Grocott, Mamas Mamas and Nick Curzen
Type: Article
| 2022
| Item not available on this server.
BSACI national allergy education strategy for healthcare professionals - Judith A. Holloway, Gillian Vance, Elizabeth Angier, Siân Ludman and Adam T. Fox
Type: Editorial
| 2022
Method development for flow-cytometric analysis of primary human airway epithelia infected with non-typeable Haemophilus influenzae - K.L. Horton, J.L. Cane, C.L. Jackson, R.N. Allan, J.S. Lucas and T.S.C. Hinks
Type: Meeting abstract
| 2022
| Item not available on this server.
Biomarkers to guide the use of antibiotics for acute exacerbations of COPD (AECOPD): a systematic review and meta-analysis - George Hoult, David Gillespie, Tom M A Wilkinson, Mike Thomas and Nick A Francis
Type: Article
| 2022
Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD - Ventzislava A. Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S. Glover, Jodie Ackland, Bastian Angermann, Graham Belfield, Maria Belvisi, Hannah Burke, Doriana Cellura, Howard W. Clark, Damla Etal, Anna Freeman, Ashley Heinson, S. Hess, Michael Hühn, Emily Hall, Alex Mackay, Jens Madsen, Christopher McCrae, Daniel Muthas, Steven Novick, Kristoffer Ostridge, Lisa Oberg, Adam Platt, Anthony Postle, Cosma Mirella Spalluto, Outi Vaarala, Junmin Wang, Karl J. Staples and Tom MA Wilkinson
Type: Article
| 2022
| Item availability restricted.
Type: Article
| 2022
Body Mass Index and clinical outcome of severe COVID-19 patients with acute hypoxic respiratory failure: unravelling the “obesity paradox” phenomenon - Michael Jennings, Maria Burova, Laura G. Hamilton, Elsie Hunter, Clare Mordena, Ryan Beecham, Darshni Pandya, Helen Moyses, Kordo Saeed, Paul Afolabi, Philip Calder and Ahilanandan Dushianthan
Type: Article
| 2022
Vaccination in pregnancy against pertussis: A consensus statement on behalf of the global pertussis initiative - Christine E Jones, Bahaa Abu-Raya, Kevin Forsyth, Scott A. Helperin, Kirsten Maertens, Chistine E. Jones, Ulrich Heininger, Daniela Hozbor, Carl Heinz Wirsing von König and Amar J. Chitkara
Type: Review
| 2022
Managing challenges in congenital CMV: current thinking - Christine E Jones, Heather Bailey, Alasdair Bamford, Anna Calvert, Robert B. Dorey, Simon B. Drysdale, Asma Khalil, Paul T. Heath, Hermione Lyall, Kate Monica Isabel Ralph, Shari Sapuan, Tushna Vandrevala, Simone Walter, Elizabeth Whittaker and Sharon Wood
Type: Article
| 2022
Immunity debt and unseasonal childhood respiratory viruses - Christine E. Jones
Type: Article
| 2022
Type: Dataset
| 2022
| University of Southampton
Type: Dataset
| 2022
| University of Southampton
Type: Dataset
| 2022
| University of Southampton
Type: Dataset
| 2022
| Journal of Extracellular Biology
Human milk extracellular vesicles preserve bronchial epithelial barrier integrity and reduce TLR3-induced inflammation in vitro - Nikita Karra, Martijn J.C Van Herwijnen, Marca H.M Wauben, Emily Swindle and Hywel Morgan
Type: Article
| 2022
Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA) - Ekaterina Khaleva, Anna Rattu and Chris Brightling
Type: Review
| 2022
Integration of genomic risk scores to improve the prediction of childhood asthma diagnosis - Dilini M. Kothalawala, Latha Kadalayil, John A. Curtin, Clare S. Murray, Angela Simpson, Adnan Custovic, William J. Tapper, S. Hasan Arshad, Faisal I. Rezwan and John W. Holloway
Type: Article
| 2022
Blueprint for harmonising unstandardised disease registries to allow federated data analysis: prepare for the future - Johannes A Kroes, Aruna T Bansal, Emmanuelle Berret, Nils Christian, Andreas Kremer, Anna Alloni, Matteo Gabetta, Chris Marshall, Scott Wagers, Ratko Djukanovic, Celeste Porsbjerg, Dominique Hamerlijnck, Olivia Fulton, Anneke Ten Brinke, Elisabeth H Bel and Jacob K Sont
Type: Article
| 2022
MicroRNAs - a promising tool for asthma diagnosis and severity assessment: a systematic review - Mohammed Aref Kyyaly, Elena Vladimirovna Vorobeva, Dilini M Kothalawala, Wei Chern Gavin Fong, Peijun He, Collin L Sones, Mohammad Al-Zahrani, Tilman Sanchez-Elsner, Syed Hasan Arshad and Ramesh J Kurukulaaratchy
Type: Article
| 2022
Temporal whole-transcriptomic analysis of characterized in vitro and ex vivo primary nasal epithelia - Jelmer Legebeke, Katie Leanne Horton, Claire Jackson, Janice Coles, Amanda Harris, Htoo Wai, John Holloway, Gabrielle Wheway, Diana Baralle and Jane Lucas
Type: Article
| 2022
3D Visualisation of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast - Rohan Lewis, Harikesan Baskaran, Jools Green, Stanimir A. Tashev, Eleni Palaiologou, Emma Lofthouse, Jane Cleal, Anthony Page, David Chatelet, Patricia Goggin and Bram Sengers
Type: Article
| 2022
Type: Dataset
| 2022
| University of Southampton
Newborn DNA methylation and asthma acquisition across adolescence and early adulthood - Liang Li, John W. Holloway, Susan Ewart, Syed Hasan Arshad, Caroline L. Relton, Wilfried Karmaus and Hongmei Zhang
Type: Article
| 2022
Does DNA methylation mediate the association of age at puberty with forced vital capacity or forced expiratory volume in 1 s? - Liang Li, Hongmei Zhang, John W. Holloway, Susan Ewart, Caroline L. Relton, S. Hasan Arshad and Wilfried Karmaus
Type: Article
| 2022
Type: Dataset
| 2022
| Zenodo
| Item not available on this server.
A scoping review: urinary markers of metabolic maturation in infants with CHD and the relationship to growth - Luise V. Marino, Simone Paulson, James J. Ashton, Charlotte Weeks, Aneurin Young, John V.P. Pappachan, Jonathan Swann, R. Mark Beattie and Mark J. Johnson
Type: Article
| 2022
Past, present and future of conservative oxygen therapy in critical care - Daniel Martin, David Harrison, Paul Mouncey, B. Ronan O'Driscoll, Mike Grocott, Lorna Miller, Doug Gould, Alvin Richards-Belle and Kathryn Rowan
Type: Article
| 2022
| Item availability restricted.
Compassionate use of Pulmonary Vasodilators in Acute Severe Hypoxic Respiratory Failure due to COVID-19 - Lewis Matthews, Laurence Baker, Matteo Ferrari, Weronika Sanchez, John Pappachan, Mike Pw Grocott, Ahilanandan Dushianthan, Thomas Wilkinson, Hannah Burke, Anna Freeman, Michael Celinski, Saul Faust, Gareth Thomas and Christopher Kipps
Type: Article
| 2022
Perioperative risk stratification and modification - Lewis Matthews, Denny Levett and Michael Grocott
Type: Review
| 2022
A systematic review and network meta-analysis of topical pharmacological, oral pharmacological, physical and combined treatments for acne vulgaris - Ifigeneia Mavranezouli, Caitlin H Daly, Nicky J Welton, Shalmali Deshpande, Laura Berg, Nathan Bromham, Stephanie Arnold, David M Phillippo, Jane Wilcock, Jingyuan Xu, Jane C Ravenscroft, Damien Wood, Mohammed Rafiq, Linyun Fou, Katharina Dworzynski and Eugene Healy
Type: Review
| 2022
Exacerbation profile and risk factors in a type-2–low enriched severe asthma cohort: a clinical trial to assess asthma exacerbation phenotypes - P. Jane McDowell, John Busby, Catherine E. Hanratty, Ratko Djukanovic, Ashley Woodcock, Samantha Walker, Timothy Colin Hardman, Joseph R. Arron, David F. Choy, Peter Bradding, Chris E. Brightling, Rekha Chaudhuri, Douglas Cowan, Adel H. Mansur, Stephen J. Fowler, Sarah E. Diver, Peter H Howarth, James L. Lordan, Andrew Menzies-Gow, Timothy G. Harrison, Douglas S. Robinson, Cecile T.J. Holweg, John C. Matthews, Ian D. Pavord and Liam G. Heaney
Type: Article
| 2022
Experiences of pregnant women and healthcare professionals of participating in a digital antenatal CMV education intervention - Amy Montague, Tushna Vandrevala, Anna Calvert, L. Ling Yeh, Caroline Star, Asma Khalil, Paul Griffiths, Paul T. Heath and Christine E. Jones
Type: Article
| 2022
The characterization of Moraxella catarrhalis carried in the general population - Denise E. Morris, Karen L. Osman, David W. Cleary and Stuart C. Clarke
Type: Article
| 2022
Parental perceptions and experiences of infant crying: a systematic review and synthesis of qualitative research - Ingrid Muller, Daniela Ghio, Jasmine Mobey, Hannah Jones, Samantha Hornsey, Amy Elizabeth Dobson, Emma Maund and Miriam Santer
Type: Article
| 2022
Preparing for disease X: ensuring vaccine equity for pregnant women in future pandemics - Flor M. Munoz, Clare L. Cutland, Christine E. Jones, Beate Kampmann, Asma Khalil, Esperança Sevene, Andy Stergachis, Geeta K. Swamy, Gerald Voss and Ajoke Sobanjo-ter Meulen
Type: Article
| 2022
Analysis of cell‐specific peripheral blood biomarkers in severe allergic asthma identifies innate immune dysfunction - Ben Nicholas, Jane Guo, Hyun‐Hee Lee, Alistair Bailey, Rene de Waal Malefyt, Milenko Cicmil and Ratko Djukanovic
Type: Letter
| 2022
Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands - Benjamin Nicholas, Alistair Bailey, Karl J. Staples, Thomas Wilkinson, Timothy Elliott and Paul Skipp
Type: Article
| 2022
Segmentation of the foveal and parafoveal retinal architecture using handheld spectral-domain optical coherence tomography in children with Down syndrome - Rory Nicholson, Daniel Osborne, Lisa Fairhead, Leonora Beed, Catherine M Hill and Helena Lee
Type: Article
| 2022
| Item not available on this server.
Differential toxicity in an alveolar epithelial cell line of fine particulate matter from brakewear, roadwear, and diesel exhaust - James Parkin, Lareb Dean, Joseph Bell, Siyuan Wang, Matthew Cooper, Natasha Hazel Celeste Easton, Robert Ridley, Franco Conforti, Helen Vethakan Raj, Julian Downward, Yihua Wang, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Richard Cook, Mark Jones, Donna Davies and Matthew Loxham
Type: Conference or Workshop Item
| 2022
| Item not available on this server.
Differential toxicity in an alveolar epithelial cell line of fine particulate matter from brakewear, roadwear, and diesel exhaust - James Parkin, Lareb Dean, Joseph Bell, Siyuan Wang, Matthew Cooper, Natasha Hazel Celeste Easton, Robert Ridley, Franco Conforti, Helen Vethakan Raj, Julian Downward, Yihua Wang, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Richard Cook, Mark Jones, Donna Davies and Matthew Loxham
Type: Conference or Workshop Item
| 2022
| Item not available on this server.
Differential toxicity in an alveolar epithelial cell line of fine particulate matter from brakewear, roadwear, and diesel exhaust - James Parkin, Lareb Dean, Joseph Bell, Siyuan Wang, Matthew Cooper, Natasha Hazel Celeste Easton, Robert Ridley, Franco Conforti, Helen Vethakan Raj, Julian Downward, Yihua Wang, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Richard Cook, Mark Jones, Donna Davies and Matthew Loxham
Type: Conference or Workshop Item
| 2022
| Item not available on this server.
British Society for Investigative Dermatology Annual Meeting 4th - 6th April 2022 Frederick Douglass Centre, Newcastle University, Newcastle Upon Tyne - Gemma Porter, Jenny Pople, Mahesan Niranjan, Michael Ardern-Jones and Marta Polak
Type: Meeting abstract
| 2022
| Item not available on this server.
Rapid phospholipid turnover after surfactant nebulization in severe COVID- 19 infection: a randomized clinical trial - Anthony Postle, Howard Clark, Jim Fink, Jens Madsen, Grielof Koster, Madhuriben Panchal, Ratko Djukanovic, David Brealey, Michael Grocott and Ahilanandan Dushianthan
Type: Article
| 2022
A 3D-induced pluripotent stem cell-derived human neural culture model to study certain molecular and biochemical aspects of Alzheimer’s disease - Preeti Prasannan, Elodie Jane Siney, Shreyasi Chatterjee, David Johnston, Mohammad Shah, Amritpal Mudher and Sandrine Willaime-Morawek
Type: Article
| 2022
Paediatric health-related quality of life in congenital cytomegalovirus - Kate Monica Isabel Ralph, Kim Bull, Caroline Trotter, Sharon Wood and Christine E Jones
Type: Article
| 2022
DNA methylation and asthma acquisition during adolescence and post-adolescence, an epigenome-wide longitudinal study - Aniruddha Rathod, Hongmei Zhang, Syed Hasan Arshad, Susan Ewart, Caroline L. Relton, Wilfried Karmaus and John W. Holloway
Type: Article
| 2022
Identifying and appraising outcome measures for severe asthma: a systematic review - Anna Rattu, Ekaterina Khaleva, Christopher E. Brightling and Graham Roberts
Type: Review
| 2022
Prehabilitation. An interdisciplinary patient-centric conceptual framework - Tessa Renouf, Andrew Bates, June F. Davis and Sandy Jack
Type: Article
| 2022
| Item availability restricted.
The association between iron deficiency and outcomes: a secondary analysis of the intravenous iron therapy to treat iron deficiency anaemia in patients undergoing major abdominal surgery (PREVENTT) trial - T. Richards, L.F. Miles, B. Clevenger, A. Keegan, S. Abeysiri, R. Rao Baikady, M.W. Besser, J.P. Browne, Andrew Klein, I.C. Macdougall, G.J. Murphy, S.D. Anker and Darren Dahly
Type: Article
| 2022
Type: Article
| 2022
An observational, cohort, multi-centre, open label phase IV extension study comparing preschool DTAP-IPV booster vaccine responses in children whose mothers were randomised to one of two pertussis-containing vaccines or received no pertussis-containing vaccine in Pregnancy in England - Shari Sapuan, Nick J. Andrews, Bassam Hallis, Laura Hole, Christine E Jones, Mary Matheson, Elizabeth Miller, Matthew D. Snape and Paul T. Heath
Type: Article
| 2022
A systematic review and meta-analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women - Shari Sapuan, Anastasia Theodosiou, Blair L. Strang, Paul T. Heath and Christine E. Jones
Type: Review
| 2022
BSACI guideline for the set-up of penicillin allergy de-labelling services by non-allergists working in a hospital setting - Louise Savic, Michael Ardern-Jones, Anthony Avery, Tim Cook, Sarah Denman, Sophie Farooque, Tomaz Garcez, Rochelle Gold, Nicola Jay, Mamidipudi Thirumala Krishna, Sue Leech, Shauna McKibben, Shuaib Nasser, Nikhil Premchand, Jonathan Sandoe, Jacqueline Sneddon and Amena Warner
Type: Article
| 2022
Preface. Enhanced recovery after surgery and perioperative medicine driving value-based surgical care - Michael Scott, Anton Krige and Michael P W Grocott
Type: Article
| 2022
| Item not available on this server.
Combined analysis of proteomic, immunophenotypical and clinicopathological data of primary cutaneous squamous cell carcinomas demonstrates key immunological correlates associated with risk of metastasis - A. Shapanis, C. Lai, G. Coltart, M. Sommerlad, J. Schofield, E. Parkinson, P. Skipp and E. Healy
Type: Meeting abstract
| 2022
| Item not available on this server.
Genome sequencing reveals underdiagnosis of primary ciliary dyskinesia in bronchiectasis - Amelia Shoemark, Helen Griffin, Gabrielle Wheway, Claire Hogg, Jane Lucas, C Camps, Jenny Taylor, Mary Carroll, Michael R. Loebinger, James D Chalmers, Deborah Morris-Rosendahl, Hannah Mitchison and Anthony De Souza
Type: Article
| 2022
Physical and psychological health behavior changes during the COVID-19 pandemic that may inform surgical prehabilitation: a narrative review - Julie K. Silver, Daniel Santa Mina, Andrew Bates, Chelsia Gillis, Emily M Silver, Tracey L. Hunter and Sandy Jack
Type: Review
| 2022
| Item not available on this server.
Association of Upper Gastrointestinal Surgery of Great Britain and Ireland (AUGIS)/Perioperative Quality Initiative (POQI) consensus statement on intraoperative and postoperative interventions to reduce pulmonary complications after oesophagectomy - Pritam Singh, James Gossage, Sheraz Markar, Philip H Pucher, Alex Wickham, Jonathan Weblin, Swathikan Chidambaram, Alexander Bull, Oliver Pickering, Monty Mythen, Nick Maynard, Mike Grocott and Tim Underwood
Type: Article
| 2022
Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation - Olivia Solomon, Karen Huen, Paul Yousefi, Leanne K. Küpers, Juan R. Gonzalez, Matthew Suderman, Sarah E. Reese, Christian M. Page, Olena Gruzieva, Peter Rzehak, Lu Gao, Kelly M. Bakulski, Alexei Novoloaca, Catherine Allard, Irene Pappa, Maria Llambrich, Marta Vives, Dereje D. Jima, Tuomas Kvist, Andrea A. Baccarelli, Cory White, Faisal I Rezwan, Gemma C. Sharp, Gwen Tindula, Anna Bergström, Veit Grote, John F Dou, Elena Isaevska, Maria C. Magnus, Eva Corpeleijn, Patrice Perron, Vincent W V Jaddoe, Ellen A. Nohr, Lea Maitre, Maria Foraster, Cathrine Hoyo, Siri E. Håberg, Jari Lahti, Dawn L. DeMeo, Hongmei Zhang, Wilfried Karmaus, Inger Kull, Berthold Koletzko, Jason I Feinberg, Luigi Gagliardi, Luigi Bouchard, Cecilia Host Ramlau-Hansen, Henning Tiemeier, Gillian Santorelli, Rachel L. Maguire, Darina Czamara, Augusto A. Litonjua, Jean-Paul Langhendries, Michelle Plusquin, Johanna Lepeule, Elisabeth B. Binder, Elvira Verduci, Terence Dwyer, Angel Carracedo, Natalia Ferre, Brenda Eskenazi, Manolis Kogevinas, Tim S. Nawrot, Monica Cheng Munthe-Kaas, Zdenko Herceg, Caroline L. Relton, Erik Melen, Dariusz Gruszfeld, Carrie Breton, M D Fallin, Akram Ghantous, Wenche Nystad, Barbara Heude, Harold Snieder, Marie-France Hivert, Janine F. Felix, Thorkild I. A. Sørensen, Mariona Bustamante, Susan K. Murphy, Katri Raikkonen, Emily Oken, John Holloway, Syed Arshad, Stephanie London and Nina Holland
Type: Review
| 2022
Type: Dataset
| 2022
| University of Southampton
Patient-centered discussions about disease progression, symptom, and treatment burden in chronic obstructive pulmonary disease could facilitate the integration of end-of-life discussions in the disease trajectory: patient, clinician, and literature perspectives: a multimethod approach - Nuno Tavares, Nikki Jarrett, Tom M.A. Wilkinson and Katherine J. Hunt
Type: Article
| 2022
HIV-associated alterations of the biophysical features of maternal antibodies correlate with their reduced transfer across the placenta - Sean A. Taylor, Shilpee Sharma, Christopher A. L. Remmel, Beth Holder, Christine E. Jones, Arnaud Marchant and Margaret E. Ackerman
Type: Article
| 2022
Potential biomarker identification by RNA-seq analysis in Antibiotic-related Drug Reaction with Sosinophilia and Systemic Symptoms (DRESS): a Pilot Study - Ying Xin Teo, Wei Yann Haw, Andreas Vallejo, Carolann Mcguire, Jeongmin Woo, Peter Simon Friedman, Michael Ardern-Jones and Marta Ewa Polak
Type: Article
| 2022
Lactamica 9: Clinical study protocol. Defining upper respiratory colonisation and microbiome evolution in mother-infant pairs following Neisseria lactamica inoculation in late pregnancy - Anastasia Theodosiou, Christine E. Jones, Robert Read, David Cleary, Jay Laver, Adam Dale, Matthew Coleman and Debby Bogaert
Type: Other
| 2022
Controlled human infection with Neisseria lactamica in late pregnancy to measure horizontal transmission and microbiome changes in mother-neonate pairs: A single-arm interventional pilot study protocol - Anastasia A Theodosiou, Jay R Laver, Adam P Dale, David W Cleary, Christine E Jones and Robert C Read
Type: Article
| 2022
Results of two online randomized controlled trials of the eczema care online intervention for parents/carers of children and young people with eczema - Kim S. Thomas, Miriam Santer, Ingrid Muller, Taeko Becque, Beth Stuart, Julie Hooper, Tracey H. Sach, Matthew J. Ridd, Amanda Roberts, Amina Ahmed, Mary Steele, Kate Greenwell, Katy Sivyer, Sylvia Wilczynska, Hywel C. Williams, Joanne R. Chalmers, Paul Leighton, Laura M. Howells, Sandra Lawton, Gareth Griffiths, Jacqui Nuttall, Hayden Kirk, Sinead M. Langan, Lucy Yardley and Paul Little
Type: Meeting abstract
| 2022
| Item not available on this server.
Association of differential mast cell activation with granulocytic inflammation in severe asthma - Angelica Tiotiu, Yusef Badi and Nazanin Zounemat Kermani
Type: Article
| 2022
| Item not available on this server.
The impact of preterm birth on sleep through infancy, childhood and adolescence and its implications - Jayne Trickett, Catherine Hill, Topun Austin and Samantha Johnson
Type: Review
| 2022
Breathing patterns and oxygenation saturation during sleep in children habitually living at high altitude in the Andes: A systematic review - Santiago Ucrós, Javier A Castro-Guevara, Catherine M Hill and Jose A Castro-Rodriguez
Type: Review
| 2022
Dietary strategies for the prevention of asthma in children - Carina Venter, Peter K Smith and Hasan Arshad
Type: Review
| 2022
Predicting the risk of chest radiograph abnormality 12-weeks post hospitalisation with SARS CoV-2 PCR confirmed COVID-19 - Tim Jm Wallis, Benjamin Welham, Alex Kong, Tommaso Morelli, Adnan Azim, Jose Horno, Miranda Wilkinson, Hannah Burke, Anna Freeman, Thomas Ma Wilkinson, Mark G Jones and Benjamin G Marshall
Type: Article
| 2022
Digital healthcare in COPD management: a narrative review on the advantages, pitfalls, and need for further research - Alastair Watson and Tom M.A. Wilkinson
Type: Review
| 2022
The Wessex Fit-4-Cancer Surgery Trial (WesFit): a protocol for a factorial-design, pragmatic randomised-controlled trial investigating the effects of a multi-modal prehabilitation programme in patients undergoing elective major intra–cavity cancer surgery - Malcolm West, Andrew Bates, Chloe Grimmett, Cait Allen, Richard Green, Lesley Hawkins, Helen Moyses, Samantha Leggett, Denny Z H Levett, Sally Rickard, Judit Varkonyi-sepp, Fran Williams, Stephen Wootton, Matthew Hayes, Michael P W Grocott and Sandy Jack
Type: Article
| 2022
The role of epigenetics in multi‐generational transmission of asthma: an NIAID workshop report‐based narrative review - Lisa M. Wheatley, John W. Holloway, Cecilie Svanes, Malcolm R. Sears, Carrie Breton, Alexey V. Fedulov, Eric Nilsson, Donata Vercelli, Hongmei Zhang, Alkis Togias and S. Hasan Arshad
Type: Review
| 2022
Changes in the growth of very preterm infants in England 2006–2018 - Aneurin Young, Tim J. Cole, Guo Cheng, Sarah Ennis, Robert M Beattie and Mark Johnson
Type: Article
| 2022
Prognostic Imaging Biomarker Discovery in Survival Analysis for Idiopathic Pulmonary Fibrosis - An Zhao, Ahmed H. Shahin, Yukun Zhou, Eyjolfur Gudmundsson, Adam Szmul, Nesrin Mogulkoc, Frouke van Beek, Christopher J. Brereton, Hendrik W. van Es, Katarina Pontoppidan, Recep Savas, Timothy Wallis, Omer Unat, Marcel Veltkamp, Mark G. Jones, Coline H.M. van Moorsel, David Barber, Joseph Jacob and Daniel C. Alexander
Type: Conference or Workshop Item
| 2022
| Springer Cham
| Item availability restricted.
Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children - Evelien R. van Meel, Sara M. Mensink-Bout and Herman T. den Dekker
Type: Article
| 2022