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Items where Division is "Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences
Clinical and Experimental Sciences" and Year is 2023

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Number of items: 172.

Article

UK-wide multicenter evaluation of second-line therapies in primary biliary cholangitis - Nadir Abbas, Emma L. Culver, Douglas Thorburn, Neil Halliday, Hannah Crothers, Jessica K. Dyson, April Phaw, Richard Aspinall, Salim I. Khakoo, Yiannis Kallis, Belinda Smith, Imran Patanwala, Anne McCune, Chenchu R. Chimakurthi, Vinod Hegade, Michael Orrell, Rebecca Jones, George Mells, Colette Thain, Robert-Mitchell Thain, David Jones, Gideon Hirschfield and Palak J. Trivedi
Type: Article | 2023

A hyperinflammation clinical risk tool, HI5-NEWS2, stratifies hospitalised COVID-19 patients to associate risk of death and effect of early dexamethasone in an observational cohort - Michael R Ardern-Jones, Hang T T Phan, Florina Borca, Matt Stammers, James Batchelor, Isabel C Reading, Sophie V Fletcher, Trevor Smith and Andrew S Duncombe
Type: Article | 2023

The haptoglobin response after aneurysmal subarachnoid haemorrhage - Soham Bandyopadhyay, Patrick Garland, Ben Gaastra, Ardalan Zolnourian, Diederik Bulters and Ian Galea
Type: Article | 2023

A randomised pilot feasibility study of eye movement desensitisation and reprocessing recent traumatic episode protocol, to improve psychological recovery following intensive care admission for COVID-19 - Andrew Bates, Hannah Golding, Sophie Rushbrook, Elan Shapiro, Natalie Pattison, David S. Baldwin, Michael P.W. Grocott and Rebecca Cusack
Type: Article | 2023

Routine, molecular point-of-care testing for SARS-CoV-2 and other respiratory viruses within an acute oncology service improves patient care - Kate R. Beard, Florina Borca, Hang Phan, Emma Brown, Paul A. Fenton, Jessica Stansby, John Defty and Tristan W. Clark
Type: Article | 2023

A questionnaire-based study exploring participant perspectives in a perinatal human challenge trial - James H.J. Bevan, Anastasia A. Theodosiou, James Corner, Robert B. Dorey, Robert C. Read and Christine E. Jones
Type: Article | 2023

Nasal nitric oxide measurement in children for the diagnosis of primary ciliary dyskinesia: European Respiratory Society technical standard - Nicole Beydon, Panayiotis Kouis, June K. Marthin, Philipp Latzin, Murielle Colas, Stephanie D. Davis, Eric G. Haarman, Amanda Harris, Claire Hogg, Emma Kilbride, Claudia E. Kuehni, Diana Marangu, Kim G. Nielsen, Catherine Prendergrast, Phil Robinson, Nisreen Rumman, Matthew Rutter, Woolf Walker, Thomas Ferkol and Jane Lucas
Type: Article | 2023

Outpatient neurology diagnostic coding: a proposed scheme for standardised implementation - Fran Biggin, Jo Knight, Rejith Dayanandan, Anthony Marson, Martin Wilson, Arani Nitkunan, David Rog, Christopher Kipps, Catherine Mummery, Adrian Williams and Hedley C.A. Emsley
Type: Article | 2023

Type: Article | 2023

Type: Article | 2023 | Item not available on this server.

Stratification of asthma by lipidomic profiling of induced sputum supernatant - Joost Brandsma, James P.R. Schofield and Xian Yang
Type: Article | 2023

Characterisation and calibration of low-cost PM sensors at high temporal resolution to reference-grade performance - Florentin M.J. Bulot, Steven J. Ossont, Andrew K.R. Morris, Philip J. Basford, Natasha H.C. Easton, Hazel L. Mitchell, Gavin L. Foster, Simon J. Cox and Matthew Loxham
Type: Article | 2023

Type: Article | 2023

The impact of parental presence restrictions on Canadian parents in the NICU during COVID-19: a national survey - Marsha Campbell-Yeo, Justine Dol, Holly McCulloch, Brianna Hughes, Amos Hundert, Fabiana Bacchini, Leah Whitehead, Jehier Afifi, Lynsey Alcock, Tanya Bishop, Jon Dorling, Rebecca Earle, Annette Elliott Rose, Darlene Inglis, Carye Leighton, Gail MacRae, Andrea Melanson, C. David Simpson and Michael Smit
Type: Article | 2023 | Item not available on this server.

Type: Article | 2023

Skin programming of inflammatory responses to Staphylococcus aureus is compartmentalized according to epidermal keratinocyte differentiation status - Kalum Clayton, Daniel J. Holbrook, Andres Vallejo, Gemma Porter, Sofia Sirvent, James Davies, Jenny Pople, Fei Ling Lim, Myron Christodoulides, Marta E. Polak and Michael R. Ardern-Jones
Type: Article | 2023

Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes - S. Cotton, M.P. McHugh, R. Dewar, J.G. Haas and K. Templeton
Type: Article | 2023

Validity of root cause analysis in investigating adverse events in psychiatry - Mayura Deshpande, Julia Sinclair and David Baldwin
Type: Article | 2023

Doxycycline for the prevention of progression of COVID-19 to severe disease requiring intensive care unit (ICU) admission: A randomized, controlled, open-label, parallel group trial (DOXPREVENT.ICU) - Raja Dhar, John Kirkpatrick, Laura Gilbert, Arjun Khanna, Mahavir Madhavdas Modi, Rakesh K Chawla, Sonia Dalal, Venkata Nagarjuna Maturu, Marcel Stern, Oliver T Keppler, Ratko Djukanovic and Stephan D Gadola
Type: Article | 2023

Distinct early cellular kinetics in participants protected against colonization upon Bordetella pertussis challenge - Annieck m. Diks, Hans De graaf, Cristina Teodosio, Rick j. Groenland, Bas De mooij, Muktar Ibrahim, Alison r. Hill, Robert c. Read, Jacques j.m. Van dongen and Magdalena a. Berkowska
Type: Article | 2023

Timing of neonatal mortality and severe morbidity during the postnatal period: a systematic review - Justine Dol, Brianna Hughes, Mercedes Bonet, Rachel Dorey, Jon Dorling, Amy Grant, Etienne V. Langlois, Joelle Monaghan, Rachel Ollivier, Robin Parker, Nathalie Roos, Heather Scott, Hwayeon Danielle Shin and Janet Curran
Type: Article | 2023

Qualitative interview study exploring the perspectives of pregnant women on participating in controlled human infection research in the UK - Robert B. Dorey, Anastasia A. Theodosiou, Robert C. Read, Tushna Vandrevala and Christine E. Jones
Type: Article | 2023

Psychological distress experienced by parents caring for an immunosuppressed child during the COVID-19 pandemic - Corine Driessens, Lynne Mills, Ravin Patel, David Culliford, Diane Gbesemete, Emma Lee, Meera Shanauk, Harry Chappell, Saul Faust and Hans De Graaf
Type: Article | 2023

Type: Article | 2023

A randomized controlled trial of nebulized surfactant for the treatment of severe COVID-19 in adults (COVSurf trial) - Ahilanandan Dushianthan, Howard W. Clark, David Brealey, Danny Pratt, James B. Fink, Jens Madsen, Helen Moyses, Lewis Matthews, Tracy Hussell, Ratko Djukanovic, Martin Feelisch, Anthony D. Postle and Michael P.W. Grocott
Type: Article | 2023

Fluid optimisation in emergency laparotomy (FLO-ELA) trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery - Mark Edwards, Gordon Forbes, Neil Walker, Dion G. Morton, Monty G. Mythen, Dave Murray, Iain Anderson, Borislava Mihaylova, Ann Thomson, Matt Taylor, Marianne Hollyman, Rachel Phillips, Keith Young, Brennan C. Kahan, Rupert M. Pearse and Mike Grocott
Type: Article | 2023

Type: Article | 2023

National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the UK - Katie Evans, Cheryl Battersby, James P. Boardman, Elaine Boyle, Will Carroll, Kate Dinwiddy, Jon Dorling, Katie Gallagher, Pollyanna Hardy, Emma Johnston, Helen Mactier, Claire Marcroft, James William Harrison Webbe and Chris Gale
Type: Article | 2023

Aneurysm management in patients over 80 years old with good grade subarachnoid haemorrhage - Frederick Ewbank, Samuel Hall, Benjamin Gaastra, Benjamin Fisher, Laura Coe, James Booker, Antony Kaldas, Ian Anderson, Giles Critchley, Mario Teo, Ahmed Toma, Rikin Trivedi, Chris Uff, Raghu Vindlacheruvu, Louise Dulhanty, Mohsen Javadpour, Daniel Walsh, James Galea, Hiren Patel and Diederik Bulters
Type: Article | 2023 | Item not available on this server.

The role of the orexin system in the neurobiology of anxiety disorders: potential for a novel treatment target - Harry A. Fagan, Nathan T.M. Huneke, Katharina Domschke and David S. Baldwin
Type: Article | 2023

Longitudinal pilot study of oxygen saturation indices in healthy preterm infants - Olivia Falconer, Savannah Ivy, Dana Le Carpentier, Johanna Gavlak, Natasha Liddle, Emily Senior, Paula Lowe, Philippa Crowley, Aneurin Young, Mark J. Johnson, Robert Mark Beattie and Hazel J. Evans
Type: Article | 2023

Defective airway intraflagellar transport underlies a combined motile and primary ciliopathy syndrome caused by IFT74 mutations - Mahmoud R. Fassad, Nisreen Rumman, Katrin Junger, Mitali.P Patel, James Thompson, Patricia Goggin, Marius Ueffing, Tina Beyer, Karsten Boldt, Jane Lucas and Hannah Mitchison
Type: Article | 2023

Feasibility, acceptability and practicality of transcranial stimulation in obsessive compulsive symptoms (FEATSOCS): a randomised controlled crossover trial - Naomi A. Fineberg, Eduardo Cinosi, Megan V.A. Smith, Amanda D. Busby, David Wellsted, Nathan T.M. Huneke, Kabir Garg, Ibrahim H. Aslan, Arun Enara, Matthew Garner, Robert Gordon, Natalie Hall, Daniel Meron, Trevor W. Robbins, Solange Wyatt, Luca Pellegrini and David S. Baldwin
Type: Article | 2023

XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression - Jack G. Fisher, Amber D.P. Doyle, Lara V. Graham, Shreyanshi Sonar, Ben Sale, Isla Henderson, Luis Del Rio, Peter W.M. Johnson, Yosef Landesman, Mark S. Cragg, Francesco Forconi, Christopher J. Walker, Salim I. Khakoo and Matthew D. Blunt
Type: Article | 2023

Efficacy and safety of abrocitinib monotherapy in adolescents and adults: a post hoc analysis of the phase 3 JAK1 atopic dermatitis efficacy and safety (JADE) REGIMEN clinical trial - Carsten Flohr, Michael J. Cork, Michael R. Ardern-Jones, Lawrence F. Eichenfield, Sébastien Barbarot, Claire Feeney, Ricardo Rojo, Irina Lazariciu and John Nesnas
Type: Article | 2023

Feasibility of home administration of nebulised interferon beta-1a (SNG001) for COVID-19: a remote study - Nick Francis, Phillip D Monk, Jacqueline Nuttall, Thomas Oliver, Catherine Simpson, Jody L. Brookes, Victoria J. Tear, Angela G. Thompson, Toby N. Batten, Marcin Mankowski and Thomas Wilkinson
Type: Article | 2023

Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage - Ben Gaastra, Poppy Duncan, Mark K. Bakker, Isabel C. Hostettler, Varinder S. Alg, Henry Houlden, Ynte M. Ruigrok, Ian Galea, Will Tapper, David Werring and Diederik Bulters
Type: Article | 2023

Type: Article | 2023

The mitochondrial protein TSPO in Alzheimer’s disease: relation to the severity of AD pathology and the neuroinflammatory environment - Emma F. Garland, Oliver Dennet, Laurie Lau, David S. Chatelet, Michel Bottlaender, James A.R. Nicoll and Delphine Boche
Type: Article | 2023

The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection - Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Benjamin Jones, Catherine Hartley, David A Matthews and Ahilanandan Dushianthan
Type: Article | 2023 | Item not available on this server.

Repair of acute respiratory distress syndrome in COVID-19 by stromal cells (REALIST-COVID Trial): A multicentre, randomised, controlled trial: a multicenter, randomized, controlled clinical trial - Ellen A Gorman, Jennifer Rynne, Hannah J Gardiner, Anthony J Rostron, Jonathan Bannard-Smith, Andrew M Bentley, David Brealey, Christina Campbell, Gerard Curley, Mike Clarke, Ahilanadan Dushianthan, Phillip Hopkins, Colette Jackson, Kallirroi Kefela, Anna Krasnodembskaya, John G Laffey, Cliona McDowell, Margaret McFarland, Jamie McFerran, Peter McGuigan, Gavin D Perkins, Jonathan Silversides, Jon Smythe, Jacqui Thompson, William S Tunnicliffe, Ingeborg Dm Welters, Laura Amado-Rodríguez, Guillermo Albaiceta, Barry Williams, Manu Shankar-Hari, Daniel F McAuley and Cecilia M O'Kane
Type: Article | 2023

Targeting KIR as a novel approach to improve CAR-NK cell function - Lara V. Graham, Jack G. Fisher, Salim I. Khakoo and Matthew D. Blunt
Type: Article | 2023

Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning? - Kayleigh Griffiths, Tomoaki Ida, Masanobu Morita, Reece J Lamb, Jordan J Lee, Michael P Frenneaux, Jon M Fukuto, Takaaki Akaike, Martin Feelisch and Melanie Madhani
Type: Article | 2023 | Item not available on this server.

Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics - Harald Hampel, Aya Elhage, Min Cho, Liana G. Apostolova, James A.R. Nicoll and Alireza Atri
Type: Article | 2023

Clinical outcomes and patient experience of biosimilar to biosimilar infliximab switching in patients with inflammatory bowel disease: a prospective, single-centre, phase IV interventional study with a nested qualitative study - Clare Harris, Richard James Harris, David Young, Martin McDonnell, Bridget Clancy, Justin Harvey, Carlos Araujo, Ines Iria, Joao Goncalves, Sue Latter and Fraser Cummings
Type: Article | 2023

Cytotoxic CD4+ tissue-resident memory T cells are associated with asthma severity - Sara Herrera-De La Mata, Ciro Ramírez-Suástegui, Heena Mistry, Francisco Emmanuel Castañeda-Castro, Mohammad A. Kyyaly, Hayley Simon, Shu Liang, Laurie Lau, Clair Barber, Monalisa Mondal, Hongmei Zhang, Syed Hasan Arshad, Ramesh J. Kurukulaaratchy, Pandurangan Vijayanand and Grégory Seumois
Type: Article | 2023

Type: Article | 2023 | Item availability restricted.

Localized microglia dysregulation impairs central nervous system myelination in development - Rebecca K. Holloway, Liang Zhang, Irene Molina-Gonzalez, Kathy Ton, James A.R. Nicoll, James P. Boardman, Yan Liang, Anna Williams and Veronique E. Miron
Type: Article | 2023

Management of Fournier's gangrene: a practical guide for clinicians - Thomas Hughes, Daniel Bowen, Kordo Saeed, Patrick Juliebø-Jones and Bhaskar Somani
Type: Article | 2023 | Item not available on this server.

Placebo effects in mental health disorders: protocol for an umbrella review - Nathan T.M. Huneke, Jay Amin, David S. Baldwin, Samuel R. Chamberlain, Christoph U. Correll, Matthew Garner, Catherine M. Hill, Ruihua Hou, Oliver D. Howes, Julia M.A. Sinclair, Marco Solmi and Samuele Cortese
Type: Article | 2023

Prone positioning in mechanically ventilated COVID-19 patients: timing of initiation and outcomes - Alexander Jackson, Florence Neyroud, Josephine Barnsley, Elsie Hunter, Ryan Beecham, Meiarasu Radharetnas, Michael P.W. Grocott and Ahilanandan Dushianthan
Type: Article | 2023

Type: Article | 2023

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications - Orestis L. Katsamenis, Philip J. Basford, Stephanie K. Robinson, Richard P. Boardman, Elena Konstantinopoulou, Peter M. Lackie, Anton Page, J. Arjuna Ratnayaka, Patricia M. Goggin, Gareth J. Thomas, Simon J. Cox, Ian Sinclair and Philipp Schneider
Type: Article | 2023

WILL (when to induce labour to limit risk in pregnancy hypertension): protocol for a multicentre randomised trial - Katie Kirkham, Sue Tohill, Jennifer A. Hutcheon, Jon Dorling, Eleni Gkini, Catherine A. Moakes, Clive Stubbs, Jim Thornton, Peter von Dadelszen and Laura A. Magee
Type: Article | 2023

Neo-train: study protocol and feasibility results for a two-arm randomized controlled trial investigating the effect of supervised exercise during neoadjuvant chemotherapy on tumour response in patients with breast cancer - Eva Kjeldsted, Gunn Ammitzbøll, Lars Bo Jørgensen, Alexey Lodin, Rasmus Dahlin Bojesen, Silvia Gonzalez Ceballos, Susanne Rosthøj, Anne-vibeke Lænkholm, Søren T. Skou, Sandy Jack, Julie Gehl and Susanne Oksbjerg Dalton
Type: Article | 2023

Type: Article | 2023

Identification of cow milk epitopes to characterize and quantify disease-specific T cells in allergic children - Sloan A. Lewis, Aaron Sutherland, Ferran Soldevila, Luise Westernberg, Minori Aoki, April Frazier, Synaida Maiche, Mich Erlewyn-Lajeunesse, Hasan Arshad, Leonard Stephanie, Susan Laubach, Jennifer A. Dantzer, Robert A. Wood, Alessandro Sette, Gregory Seumois, Pandurangan Vijayanand and Bjoern Peters
Type: Article | 2023

Type: Article | 2023

Programmed cell death-1 receptor mediated regulation of Tbet+ NK1.1- innate lymphoid cells within the tumor microenvironment - Jing Xuan Lim, Chester Lai, Grace Mallett, David McDonald, Gillian Hulme, Stephanie Laba, Andrew Shapanis, Megan Payne, Warren Patterson, Michael Alexander, Jonathan Coxhead, Andrew Filby, Ruth Plummer, Penny E. Lovat, Guiseppe Sciume, Eugene Healy and Shoba Amarnath
Type: Article | 2023

Persistence of immune responses after heterologous and homologous third COVID-19 vaccine dose schedules in the UK: eight-month analyses of the COV-BOOST trial - Xinxue Liu, Alasdair P.S. Munro, Annie Wright, Gavin Babbage, Katrina Cathie, Christine E. Jones, Daniel R. Owens, Robert C. Read and Saul N. Faust
Type: Article | 2023

Position paper: models of post-transplant care for individuals with cystic fibrosis - Edward McKone, Kathleen J. Ramos, Cecilia Chaparro, Joshua Blatter, Ramsey Hachem, Michael Anstead, Fanny Vlahos, Abby Thaxton, Sarah Hempstead, Thomas Daniels, Michelle Murray, Amparo Sole, Robin Vos, Erin Tallarico, Albert Faro and Joseph M. Pilewski
Type: Article | 2023

Global burden of cardiovascular diseases and risks, 1990-2022 - George A. Mensah, Valentin Fuster, Christopher J.L. Murray and Gregory A. Roth
Type: Article | 2023 | Item not available on this server.

Frail2Fit study protocol: a feasibility and acceptability study of a virtual multimodal intervention delivered by volunteers to improve functional outcomes in older adults with frailty after discharge from hospital - Samantha Jane Meredith, Helen Roberts, Michael P.W. Grocott, Sandy Jack, Jane Murphy, Judit Varkonyi-Sepp, Andrew Bates and Stephen Eu Ruen Lim
Type: Article | 2023

Type: Article | 2023

Increase in Matrix Metaloproteinase‐10 is associated with tau, neurodegeneration and reduced brain perfusion in the right temporal lobe - Sofia Michopoulou, Angus Prosser, John Dickson, Matt J. Guy, Jessica Teeling and Christopher Kipps
Type: Article | 2023 | Item not available on this server.

Perfusion imaging and inflammation biomarkers provide complementary information in Alzheimer’s disease - Sofia Michopoulou, Angus Prosser, John Dickson, Matthew Guy, Jessica L. Teeling and Christopher Kipps
Type: Article | 2023

CSF markers of inflammation help identify tau pathology but not amyloid in a heterogenous clinical population - Sofia Michopoulou, Angus Prosser, Christopher Kipps, John Dickson, Matt J. Guy and Jessica Teeling
Type: Article | 2023

Brain PET and SPECT imaging and quantification: a survey of the current status in the UK - Sofia K. Michopoulou, John C. Dickson, Glen G. Gardner, Thomas R. Gee, Andrew J. Fenwick, Timothy Melhuish, Clare A. Monaghan, Neil O'Brien, Angus M.J. Prosser, Catherine J. Scott, Roger T. Staff and Jonathan Taylor
Type: Article | 2023

Type: Article | 2023

Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses - Muhammad Mumin, Cathrine McKenzie, Valerie Page, Leanne Aitken, Mike Grocott, Emma Cunningham, Fraser Hanks, Daniel Hadfield, A.J.C. Slooter, Edwin van Dellen, D.F. McAuley and Peter E. Spronk
Type: Article | 2023 | Item availability restricted.

The disease burden of respiratory syncytial virus in Infants - Alasdair P.S. Munro, Federico Martinón-Torres, Simon B. Drysdale and Saul N. Faust
Type: Article | 2023

Type: Article | 2023 | Item not available on this server.

Clinical impact of anti-inflammatory microglia and macrophage phenotypes at glioblastoma margins - Imran Noorani, Kastytis Sidlauskas, Sean Pellow, Reece Savage, Jeannette L. Norman, David S. Chatelet, Mark Fabian, Paul Grundy, Jeng Ching, James A.R. Nicoll and Delphine Boche
Type: Article | 2023

Type: Article | 2023

Preimplantation or gestation/lactation high-fat diet alters adult offspring metabolism and neurogenesis - Diego Armando Ojeda Pedraza, Oliver James Hutton, Robert Hopkins, Felino Cagampang, Neil Smyth, Thomas Fleming, Judith Eckert and Sandrine Willaime-Morawek
Type: Article | 2023

Evaluating the cost implications of integrating SARS-CoV-2 genome sequencing for infection prevention and control investigation of nosocomial transmission within hospitals - M Panca, J Blackstone, O Stirrup, M-T Cutino-Moguel, E Thomson, C Peters, L B Snell, G Nebbia, A Holmes, A Chawla, N Machin, Y Taha, T Mahungu, T Saluja, T I de Silva, Kordo Saeed, C Pope, G Y Shin, R Williams, A Darby, D L Smith, M Loose, S C Robson, K Laing, D G Partridge, J R Price and J Breuer
Type: Article | 2023 | Item not available on this server.

The relationship of separation anxiety with the age of onset of panic disorder - Stefano Pini, Barbara Milrod, David S Baldwin, Miriam A Schiele, Gabriele Massimetti, Barbara Costa, Claudia Martini, Borwin Bandelow, Katharina Domschke and Marianna Abelli
Type: Article | 2023

Differing impact of the COVID-19 pandemic on youth mental health: combined population and clinical study - Lu Qi MB, Zuo Zhang, Lauren Robinson, Marina Bobou, Chantal Gourlan, Jean Winterer, Rebecca Adams, Kofoworola Agunbiade, Sinead King, Nilakshi Vaidya, Eric Artiges, Tobias Banaschewski and Arun L.W. Bokde
Type: Article | 2023

Aspergillus fumigatus causing vertebral osteomyelitis in an immunocompetent patient: a case report and literature review - Thomas A.N. Reed, Anan Shtaya, Kate Beard, Kordo Saeed, Sarah Glover, Mark Fabian, Mohammad Baraka and Stephen McGillion
Type: Article | 2023 | Item not available on this server.

An Explorative Study into the Aetiology of Developmental Dysplasia of the Hip Using Targeted Urine Metabolomics - Amanda M L Rhodes, Sehrish Ali, Magdalena Minnion, Ling H Lee, Brijil M Joseph, Judwin Ndzo, Nicholas M P Clarke, Martin Feelisch and Alexander Aarvold
Type: Article | 2023 | Item not available on this server.

Operando NMR metabolomics of a microfluidic cell culture - Genevieve Alice Rogers, Sylwia Ostrowska, Manvendra Sharma, Salim Khakoo and Marcel Utz
Type: Article | 2023

Staffing levels and hospital mortality in England: a national panel study using routinely collected data - Bruna Rubbo, Christina Saville, Chiara Dall'ora, Lesley Turner, Jeremy Jones, Jane Ball, David Culliford and Peter Griffiths
Type: Article | 2023

Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism - Aida Sanchez-Bretano, Eloise Keeling, Jennifer A. Scott, Savannah A. Lynn, Sudha Priya Soundara-Pandi, Sarah L. Macdonald, Tutte Newall, Helen Griffiths, Andrew J. Lotery, J. Arjuna Ratnayaka, Jay E. Self and Helena Lee
Type: Article | 2023

Co-existence of psoriasis and cutaneous T-cell lymphoma - Joseph Scott, Chester Lai, George Stewart Coltart and Eugene Healy
Type: Article | 2023

Type: Article | 2023 | Item not available on this server.

Short, medium, and long deferral of umbilical cord clamping compared with umbilical cord milking and immediate clamping at preterm birth: a systematic review and network meta-analysis with individual participant data - Anna Lene Seidler, Sol Libesman, Kylie E. Hunter, Angie Barba, Mason Aberoumand, Jonathan G. Williams, Nipun Shrestha, Jannik Aagerup, James X. Sotiropoulos, Alan A. Montgomery, Gillian M L Gyte, Lelia Duley and Lisa M. Askie
Type: Article | 2023 | Item not available on this server.

Dexmedetomidine and propofol sedation in critically ill patients and dose-associated 90-day mortality: a secondary cohort analysis of a randomized controlled trial (SPICE III) - Yahya Shehabi, Ary Serpa-Neto, Rinaldo Bellomo, Belinda D. Howe, Yaseen M. Arabi, Michael Bailey, Frances E. Bass, Suhaini Bin Kadiman, Colin J. McArthur, Michael C. Reade, Ian M. Seppelt, Jukka Takala and Matt P. Wise
Type: Article | 2023 | Item not available on this server.

Management of medically assisted withdrawal from alcohol in acute adult mental health and specialist addictions in-patient services: UK clinical audit findings - Julia Sinclair, Thomas R E Barnes, Anne Lingford-Hughes, Colin Drummond, Ignatius Loubser, Olivia Rendora and Carol Paton
Type: Article | 2023

Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis - Sofia Sirvent, Andres S. Vallejo, Emma Corden, Ying Teo, James Davies, Kalum Clayton, Eleanor G. Seaby, Chester Lai, Sarah Ennis, Rfeef Alyami, Gemma Douilhet, Lareb S.N. Dean, Matthew Loxham, Sarah Horswill, Eugene Healy, Graham Roberts, Nigel J. Hall, Peter Friedmann, Harinder Singh, Clare L. Bennett, Michael R. Ardern-Jones and Marta E. Polak
Type: Article | 2023

Type: Article | 2023

Mitochondrial dysfunction in CD4+ T effector memory RA+ cells - Marie Strickland, Salanne Lee, Shi-Yong Neo, Akhila Balachander, Ivy Low, Seri Mustafah, Go Wah Ing, Graham Wright, Anis Larbi and Sylvia L F Pender
Type: Article | 2023

Type: Article | 2023

Utility and safety of skin tests in drug reaction with eosinophilia and systemic symptoms (DRESS): a systematic review - Ying Xin Teo, Peter Simon Friedmann, Marta Ewa Polak and Michael Roger Ardern-Jones
Type: Article | 2023

Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials - Sophie Thomas, Leanne Embry, Karin Walsh, Kim Bull, Richard Grundy, Colin Kennedy, Jurgen Lemiere, Pablo Hernáiz Driever, Jennifer Limond, Mathilde Chevignard and Kristina Hardy
Type: Article | 2023

In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs - Luke D. Tyson, Stephen Atkinson, Robert W. Hunter, Michael Allison, Andrew Austin, James W. Dear, Ewan Forrest, Tong Liu, Emma Lord, Steven Masson, Joao Nunes, Paul Richardson, Stephen D. Ryder, Mark Wright, Mark Thursz and Nikhil Vergis
Type: Article | 2023

Quantification of lung surfactant lipid (dipalmitoylphosphatidylcholine/sphingomyelin) ratio in binary liposomes using Raman spectroscopy - Aneesh Vincent Veluthandath, Waseem Ahmed, Jens Madens, Howard W. Clark, Anthony D. Postle, James S. Wilkinson and Ganapathy Senthil Murugan
Type: Article | 2023

Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study - Kate F. Walker, Eleanor J. Mitchell, Susan Ayers, Nia W. Jones, Reuben Ogollah, Natalie Wakefield, Jon Dorling, Phoebe Pallotti, Arani Pillai, Nicola Tempest, Rachel Plachcinski, Lucy Bradshaw, Marian Knight and Jim G. Thornton
Type: Article | 2023

Individualised exercise training enhances antioxidant buffering capacity in idiopathic pulmonary fibrosis - Tim J.M. Wallis, Magdalena Minnion, Anna Freeman, Andrew Bates, James M. Otto, Stephen A. Wootton, Sophie V. Fletcher, Michael P.W. Grocott, Martin Feelisch, Mark G. Jones and Sandy Jack
Type: Article | 2023

Type: Article | 2023

Transcriptomic analysis of cutaneous squamous cell carcinoma reveals a multi-gene prognostic signature associated with metastasis - Jun Wang, Catherine A. Harwood, Emma Bailey, Findlay Bewicke-Copley, Chinegu Anthony Anene, Jason Thomson, Mah Jabeen Qamar, Rhiannon Laban, Craig Nourse, Christina Schoenherr, Mairi Treanor-Taylor, Eugene Healy, Chester Lai, Paul Craig, Colin Moyes, William Rickaby, Joanne Martin, Charlotte Proby, Gareth J. Inman and Irene M. Leigh
Type: Article | 2023

UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases - Alasdair N. Warwick, Katie Curran, Barbra Hamill, Kelsey Stuart, Anthony P. Khawaja, Paul J. Foster, Andrew J. Lotery, Michael Quinn, Savita Madhusudhan, Konstantinos Balaskas and Tunde Peto
Type: Article | 2023

Severe parainfluenza viral infection-a retrospective study of adult intensive care patients - Adam Watson, Ryan Beecham, Michael P.W. Grocott, Kordo Saeed and Ahilanandan Dushianthan
Type: Article | 2023

Towards precision medicine in COPD: bioradiomic SPECT-CT quantification of active lung inflammation - Benjamin Welham, Michael Bennett, Kristoffer Ostridge, Matthew Guy, Clint Zvavamwe, Francis Sundram and Tom Wilkinson
Type: Article | 2023 | Item not available on this server.

Type: Article | 2023

Mechanisms affecting the gut of preterm infants in enteral feeding trials: a nested cohort within a randomised controlled trial of lactoferrin - Greg Young, Janet E. Berrington, Stephen Cummings, Jon Dorling, Andrew K. Ewer, Alessandra Frau, Lauren Lett, Chris Probert, Ed Juszczak, John Kirby, Lauren C. Beck, Victoria L. Renwick, Christopher Lamb, Clare V. Lanyon, William McGuire, Christopher Stewart and Nicholas Embleton
Type: Article | 2023

Mortality surrogates in combined pulmonary fibrosis and emphysema - An Zhao, Eyjolfur Gudmundsson, Nesrin Mogulkoc and Mark G. Jones
Type: Article | 2023

Effect of acceptance and commitment therapy for depressive disorders: a meta-analysis - Bing Zhao, Qian Wang, Liping Wang, Jie Chen, Tongtong Yin, Jingxuan Zhang, Xiaojing Cheng and Ruihua Hou
Type: Article | 2023

Book Section

Anxiety disorders - Nathan Huneke, Bethan Impey and David Baldwin
Type: Book Section | 2023 | Cambridge University Press | Item not available on this server.

Correlative multiscale microCT-SBF-SEM imaging of resin-embedded tissue - Davis Laundon, Orestis L. Katsamenis, James Thompson, Patricia Goggin, David S. Chatelet, Pascale Chavatte-Palmer, Neil J. Gostling and Rohan M. Lewis
Type: Book Section | 2023 | Academic Press | Item not available on this server.

Conference or Workshop Item

Computational notebooks as co-design tools: engaging young adults living with diabetes, family carers, and clinicians with machine learning models - Amid Ayobi, Jacob Hughes, Christopher J Duckworth, Jakub J. Dylag, Sam James, Paul Marshall, Matthew Guy, Anitha Kumaran, Adriane Chapman, Michael Boniface and Aisling Ann O'Kane
Type: Conference or Workshop Item | 2023 | Association for Computing Machinery | Item availability restricted.

Developing a UHS clinical service for investigating early pregnancy loss: utilising μCT as a less invasive alternative to conventional autopsy - Orestis L. Katsamenis, Patricia Goggin, Sofia Michopoulou, Nadine Duffin, Ian Simcock, J. Ciaran Hutchinson, Owen Arthurs and Linden Stocker
Type: Conference or Workshop Item | 2023 | Item not available on this server.

Type: Conference or Workshop Item | 2023

Improving tuberculosis treatment using mid-infrared spectroscopy for bedside therapeutic drug monitoring - David J. Rowe, Daniel R. Owens, Miloš Nedeljković, Callum J. Stirling, Katrina Cathie, Suzanne L. Parker, Saul N. Faust, Goran Z. Mashanovich and James S. Wilkinson
Type: Conference or Workshop Item | 2023 | SPIE

Vibrational spectroscopy for rapid bedside medical diagnosis - Aneesh Vincent Veluthandath, Waseem Ahmed, Eleanor Louisa Osborne, Ahilanandan Dushianthan, Jens Madsen, Howard W. Clark, Anthony Postle, James S Wilkinson and Ganapathy Senthil Murugan
Type: Conference or Workshop Item | 2023 | Item not available on this server.

Bioradiomic SPECT-CT quantification of active lung inflammation is influenced by heterogeneity of lung tissue - Benjamin Welham, Michael Bennett, Kristoffer Ostridge, Matthew Guy, Clint Zvavamwe, Francis Sundram and Tom Wilkinson
Type: Conference or Workshop Item | 2023 | Item not available on this server.

Thesis

Type: Thesis | 2023 | University of Southampton | Item availability restricted.

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton | Item availability restricted.

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton | Item availability restricted.

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton | Item availability restricted.

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton

Type: Thesis | 2023 | University of Southampton | Item availability restricted.

Dataset

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | Zenodo | Item not available on this server.

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | Zenodo | Item not available on this server.

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | Zenodo | Item not available on this server.

Type: Dataset | 2023 | University of Southampton

Type: Dataset | 2023 | University of Southampton

Letter

Early life exposure to antibiotics and laxatives in relation to infantile atopic eczema. - Sarah El-Heis, Sarah Crozier, Nicholas Harvey, Eugene Healy and Keith Godfrey
Type: Letter | 2023

Reply to Fuxench et al - Sarah El-Heis, Sarah Crozier, Nicholas Harvey, Eugene Healy and Keith M. Godfrey
Type: Letter | 2023

Long COVID: potential role of the reactive species interactome - Martin Feelisch, Anna D. Clark, Andrew F. Cumpstey, Jérôme Santolini and Alan A. Jackson
Type: Letter | 2023

A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression - Sameer Jauhar, Danilo Arnone, David S. Baldwin, Michael Bloomfield, Michael Browning, Anthony J. Cleare, Phillip Corlett, J.F. William Deakin, David Erritzoe, Cynthia Fu, Paolo Fusar-Poli, Guy M. Goodwin, Joseph Hayes, Robert Howard, Oliver D. Howes, Mario F. Juruena, Raymond W. Lam, Stephen M. Lawrie, Hamish McAllister-Williams, Steven Marwaha, David Matuskey, Robert A. McCutcheon, David J. Nutt, Carmine Pariante, Toby Pillinger, Rajiv Radhakrishnan, James Rucker, Sudhakar Selvaraj, Paul Stokes, Rachel Upthegrove, Nefize Yalin, Lakshmi Yatham, Allan H. Young, Roland Zahn and Philip J. Cowen
Type: Letter | 2023

Type: Letter | 2023 | Item not available on this server.

Review

T lymphocytes and their potential role in dementia with Lewy bodies - Jay Amin, Claire Gee, Kiran Stowell, Daisy Coulthard and Delphine Boche
Type: Review | 2023

Uncoupled redox stress: how a temporal misalignment of redox-regulated processes and circadian rhythmicity exacerbates the stressed state - Anna D. Clark, Andrew F. Cumpstey, Jérôme Santolini, Alan A. Jackson and Martin Feelisch
Type: Review | 2023

Standardizing case definitions for monitoring the safety of maternal vaccines globally: GAIA definitions, a review of progress to date - Hannah G. Davies, Conor Bowman, Gabriella Watson, Caitlin Dodd, Christine E. Jones, Flor M. Munoz, Paul T. Heath, Clare L. Cutland and Kirsty Le Doare
Type: Review | 2023

Alveolar hyperoxia and exacerbation of lung injury in critically Ill SARS-CoV-2 pneumonia - Ahilanandan Dushianthan, Luke Bracegirdle, Rebecca Cusack, Andrew F. Cumpstey, Anthony D Postle and Michael P.W. Grocott
Type: Review | 2023

A role for genetic modifiers in tubulointerstitial kidney diseases - Gary P. Leggatt, Eleanor G. Seaby, Kristin Veighey, Christine Gast, Rodney Gilbert and Sarah Ennis
Type: Review | 2023

Type: Review | 2023

Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in extremely preterm infants: a clinical practice guideline incorporating family values and preferences - Souvik Mitra, Leah Whitehead, Katie Smith, Breagh MacLean, Rebekah Nixon, Andrew Veysey, Marsha Campbell-Yeo, Stefan Kuhle, Chris Gale, Roger Soll, Jon Dorling and Bradley C. Johnston
Type: Review | 2023 | Item not available on this server.

Selective serotonin reuptake inhibitors, post-treatment sexual dysfunction and persistent genital arousal disorder: a systematic review - Livio Tarchi, Giuseppe Pierpaolo Merola, Ottone Baccaredda-Boy, Francesca Arganini, Emanuele Cassioli, Eleonora Rossi, Mario Maggi, David S. Baldwin, Valdo Ricca and Giovanni Castellini
Type: Review | 2023

Type: Review | 2023

Review of the British thoracic society winter meeting 23 November 2022 23-25 November 2022 - Tom Ward, Akhilesh Jha, Enya Daynes, Jodie Ackland and James Chalmers
Type: Review | 2023

Anomalies in the review process and interpretation of the evidence in the NICE guideline for chronic fatigue syndrome and myalgic encephalomyelitis - Peter White, Susan Abbey, Brian Angus, Harriet A. Ball, Dedra S. Buchwald, Christine Burness, Alan J. Carson, Trudie Chalder, Daniel J. Clauw, Jan Coebergh, Anthony S. David, Barbara A. Dworetzky, Mark J. Edwards, Alberto J. Espay, John Etherington, Per Fink, Signe Flottorp, Béatrice Garcin, Paul Garner, Paul Glasziou, Willie Hamilton, Peter Henningsen, Ingrid Hoeritzauer, Mujtaba Husain, Anne Catherine M.L. Huys, Hans Knoop, Kurt Kroenke, Alexander Lehn, James L. Levenson, Paul Little, Andrew Lloyd, Ira Madan, Jos W.M. Van Der Meer, Alastair Miller, Maurice Murphy, Irwin Nazareth, David L. Perez, Wendy Phillips, Markus Reuber, Winfried Rief, Alastair Santhouse, Tereza Serranova, Michael Sharpe, Biba Stanton, Donna E. Stewart, Jon Stone, Michele Tinazzi, Derick T. Wade, Simon C. Wessely, Vegard Wyller and Adam Zeman
Type: Review | 2023

Optimising growth in very preterm infants: reviewing the evidence - Aneurin Young, R. Mark Beattie and Mark John Johnson
Type: Review | 2023

Meeting abstract

Examining the microglial TSPO phenotype in Alzheimer’s disease - Emma F. Garland, Laura Kulagowska and Thomas Scott
Type: Meeting abstract | 2023

Other

A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifiesANXA1as a susceptibility locus for persistent wheezing - R Granell, JA Curtin, S Haider, N Kitaba, S Mathie, L Gregory, LL Yates, M Tutino, J Hankinson, M Perretti, JM Vonk, SH Arshad, P Cullinan, S Fontanella, G Roberts, GH Koppelman, A Simpson, S Turner, CS Murray, C.M. Lloyd, JW Holloway and A Custovic
Type: Other | 2023

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