Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences
Cancer Sciences" and Year is 2017
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Number of items: 53.
Clinical importance of DNA methylation signatures in chronic lymphocytic leukaemia patients treated with chemo-immunotherapy - Harindra Amarasinghe, Tomasz K. Wojdacz, Matthew John Jerome Rose-Zerilli, Alice Beattie, Jade Forster, Latha Kadalayil, Stuart Blakemore, Helen Parker, Marta Larrayoz, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J. Steele, Richard Rosenquist, Andrew Collins, Andrew Pettitt, Peter Hillmen, Pauline Robbe, Christopher Plass, Anna Schuh, Daniel Catovsky, David Oscier, Christopher C. Oakes and Jonathan C. Strefford
Type: Meeting abstract
| 2017
| Item not available on this server.
A PML/Slit axis controls physiological cell migration and cancer invasion in the CNS - Valeria Amodeo, Deli A, Joanne Betts, Stefano Bartesaghi, Ying Zhang, Angela Richard-Loendt, Matthew Ellis, Rozita Roshani, Mikaela Vouri, Sara Galavotti, Sarah Oberndorfer, Ana Paula Leite, Alan Mackay, Aikaterini Lampada, Eva Wessel Stratford, Ning Ning Li, David Dinsdale, David Grimwade, Chris Jones, Pierluigi Nicotera, David Michod, Sebastian Brandner and Paolo Salomoni
Type: Article
| 2017
The contribution of gene mutations to long-term clinical outcomes: data from the randomised UK LRF CLL4 trial - Stuart Blakemore, Ruth Clifford, Pavlos Antoniou, Helen Parker, Pauline Robbe, Marta Larrayoz, Zadie Davis, Latha Kadalyayil, Andrew Collins, Jade Forster, Monica Else, Andrew J. Steele, Jacqueline Chan, Graham Speight, Mark Cragg, Matthew John Jerome Rose-Zerilli, Daniel Catovsky, David Oscier, Anna Schuh and Jonathan C. Strefford
Type: Meeting abstract
| 2017
| Item not available on this server.
Clinical and biological implications of genomic lesions in Chronic Lymphocytic Leukaemia - Stuart James Blakemore
Type: Thesis
| 2017
| University of Southampton
The dual Syk/JAK inhibitor cerdulatinib antagonizes B-cell receptor and microenvironmental signaling in chronic lymphocytic leukemia - Matthew D. Blunt, Stefan Koehrer, Rachel C. Dobson, Marta Larrayoz, Sarah Wilmore, Alice Hayman, Jack Parnell, Lindsay D. Smith, Andrew Davies, Peter W.M. Johnson, Pamela B. Conley, Anjali Pandey, Jonathan C. Strefford, Freda K. Stevenson, Graham Packham, Francesco Forconi, Greg P Coffey, Jan A. Burger and Andrew J. Steele
Type: Article
| 2017
Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington's disease mice - Marie Bondulich, Nelly Jolinon, Georgina F Osborne, Edward J Smith, Ivan Rattray, Andreas Neueder, Kirupa Sathasivam, Mhoriam Ahmed, Nadira Ali, Agnesska C Benjamin, Xiaoli Chang, James R T Dick, Matthew Ellis, Sophie A Franklin, Daniel Goodwin, Linda Inuabasi, Hayley Lazell, Adam Lehar, Angela Richard-Loendt, Jim Rosinski, Donna L Smith, Tobias Wood, Sarah J Tabrizi, Sebastian Brandner, Linda Greensmith, David Howland, Ignacio Munoz-Sanjuan, Se-Jin Lee and Gillian P Bates
Type: Article
| 2017
Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology - Patience T. Brace, Liku B. Tezera, Magdalena K. Bielecka, Toby Mellows, Diana Garay, Shuye Tian, Lucinda Rand, Justin Green, Sanjay Jogai, Andrew J. Steele, Timothy M. Millar, Tilman Sanchez-Elsner, Jon S. Friedland, Christopher G. Proud and Paul T. Elkington
Type: Article
| 2017
Tumor Necrosis Factor (TNF) bioactivity at the site of an acute cell-mediated immune response Is preserved in rheumatoid arthritis patients responding to Anti-TNF therapy - Rachel Byng-Maddick, Carolin T Turner, Gabriele Pollara, Matthew Ellis, Naomi J Guppy, Lucy C K Bell, Michael R Ehrenstein and Mahdad Noursadeghi
Type: Article
| 2017
PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis - Matthew Carter, Kerry Cox, Stuart Blakemore, Anna Turaj, Robert Oldham, Lekh Dahal, Stacey Tannheimer, Francesco Forconi, Graham Packham and Mark Cragg
Type: Article
| 2017
Training improves the interobserver agreement of the expert positron emission tomography review panel in primary mediastinal B-cell lymphoma: interim analysis in the ongoing International Extranodal Lymphoma Study Group-37 study - Luca Ceriani, Sally Barrington, Alberto Biggi, Bogdan Malkowski, Ur Metser, Annibale Versari, Maurizio Martelli, Andrew Davies, Peter W Johnson, Emanuele Zucca and Stéphane Chauvie
Type: Review
| 2017
| Item availability restricted.
Positron emission tomography/computed tomography assessment after immunochemotherapy and irradiation using the lugano classification criteria in the IELSG-26 study of primary mediastinal B-cell lymphoma - Luca Ceriani, Maurizio Martelli, Maria K Gospodarowicz, Umberto Ricardi, Andrés J M Ferreri, Annalisa Chiappella, Caterina Stelitano, Monica Balzarotti, Maria E Cabrera, David Cunningham, Attilio Guarini, Pier Luigi Zinzani, Luca Giovanella, Peter W M Johnson and Emanuele Zucca
Type: Article
| 2017
| Item not available on this server.
Remote focusing multifocal plane microscopy for the imaging of 3D single molecule dynamics with cellular context - Jerry Chao, Ramraj Velmurugan, Sungyong You, Dongyoung Kim, E. Sally Ward and Raimund J. Ober
Type: Conference or Workshop Item
| 2017
| SPIE
| Item not available on this server.
Antibody distance from the cell membrane regulates antibody effector mechanisms - Kirstie Cleary, H.T. Claude Chan, Sonya James, Martin J. Glennie and Mark S. Cragg
Type: Article
| 2017
| Item availability restricted.
Development of a T cell receptor mimic antibody against wild-type p53 for cancer immunotherapy - Mark Cragg, Demin Li, Caroline Bentley, Amanda Anderson, Sarah Wiblin, Kirstie Cleary, Sofia Koustoulidou, Tasneem Hassanali, Jenna Yates, Jenny Grieg and Iva Trenevska
Type: Article
| 2017
A phase 2/3 multicenter, randomized, open-label study to compare the efficacy and safety of Lenalidomide versus investigator's choice in patients with relapsed or refractory diffuse large B-Cell lymphoma - Myron S. Czuczman, Marek Trněný, Andrew Davies, Simon Rule, Kim M. Linton, Nina Wagner-Johnston, Randy D. Gascoyne, Graham W Slack, Pierre Brousset, David A. Eberhard, Francisco J. Hernandez-Ilizaliturri, Gilles Salles, Thomas E. Witzig, Pier Luigi Zinzani, George W. Wright, Louis M. Staudt, Yandan Yang, P. Mickey Williams, Chih-Jian Lih, Jacqueline Russo, Anjan Thakurta, Patrick Hagner, Pierre Fustier, Dale Song and Ian D. Lewis
Type: Article
| 2017
| Item not available on this server.
Tailoring front-line therapy in diffuse large B-cell lymphoma: Who should we treat differently? - Andrew Davies
Type: Review
| 2017
| Item not available on this server.
Subcutaneous Rituximab for the treatment of B-cell hematologic malignancies: a review of the scientific rationale and clinical development - Andrew Davies, Claude Berge, Axel Boehnke, Anjum Dadabhoy, Pieternella Lugtenburg, Simon Rule, Mathias Rummel, Christine McIntyre, Rodney Smith and Xavier Badoux
Type: Review
| 2017
Efficacy and safety of subcutaneous rituximab versus intravenous rituximab for first-line treatment of follicular lymphoma (SABRINA): a randomised, open-label, phase 3 trial - Andrew Davies, Francesco Merli, Biljana Mihaljević, Santiago Mercadal, Noppadol Siritanaratkul, Philippe Solal-Céligny, Axel Boehnke, Claude Berge, Magali Genevray, Artem Zharkov, Mark Dixon, Michael Brewster, Martin Barrett and David MacDonald
Type: Article
| 2017
| Item not available on this server.
Engineered clearing agents for the selective depletion of antigen-specific antibodies - Siva Charan Devanaboyina, Priyanka Khare, Dilip K. Challa, Raimund J. Ober and E. Sally Ward
Type: Article
| 2017
Accelerated senescence of cancer stem cells: A failure to thrive or a route to survival? - Jekaterina Erenpreisa, Kristine Salmina and Mark Steven Cragg
Type: Book Section
| 2017
| Intech
| Item not available on this server.
Type: Letter
| 2017
| Item not available on this server.
Type: Letter
| 2017
| Item not available on this server.
Review of outcomes of percutaneous endoscopic gastrostomy tube placement in an elderly cohort following the introduction of a referral pathway - K Hedges, S Ivatts, M Stammers and E Murphy
Type: Article
| 2017
| Item not available on this server.
Shooting for the moon: Using tissue-mimetic hydrogels to gain new insight on cancer biology and screen therapeutics - Samantha E. Holt, E. Sally Ward, Raimund J. Ober and Daniel L. Alge
Type: Article
| 2017
| Item not available on this server.
Automatic endosomal structure detection and localization in fluorescence microscopic images - Dongyun Lin, Zhiping Lin, Ramraj Velmurugan and Raimund J. Ober
Type: Conference or Workshop Item
| 2017
| IEEE
| Item not available on this server.
Modelling of cancer patient records: A structured approach to data mining and visual analytics - Jing Lu, Alan Hales and David Rew
Type: Conference or Workshop Item
| 2017
| Springer
| Item not available on this server.
Obinutuzumab for the first-line treatment of follicular lymphoma - Robert Marcus, Andrew Davies, Kiyoshi Ando, Wolfram Klapper, Stephen Opat, Carolyn Owen, Elizabeth Phillips, Randeep Sangha, Rudolf Schlag, John F Seymour, William Townsend, Marek Trněný, Michael Wenger, Günter Fingerle-Rowson, Kaspar Rufibach, Tom Moore, Michael Herold and Wolfgang Hiddemann
Type: Article
| 2017
| Item not available on this server.
Therapeutic antibodies: What have we learnt from targeting CD20 and where are we going? - Michael J.E. Marshall, Richard Stopforth and Mark S. Cragg
Type: Article
| 2017
Neuropathology of SUDEP: role of inflammation, blood-brain barrier impairment, and hypoxia - Zuzanna Michalak, Dima Obari, Matthew Ellis, Maria Thom and Sanjay M Sisodiya
Type: Article
| 2017
Tumour diameter is not reliable for management of non-secreting pancreatic neuroendocrine tumours - Logan Mills, Panagiotis Drymousis, Yogesh Vashist, Christoph Burdelski, Andreas Prachalias, Parthi Srinivasan, Krishna Menon, Corina Cotoi, Saboor Khan, Judith Cave, Thomas Armstrong, Martin O Weickert, Jakob Izbicki, Joerg Schrader, Andreja Frilling, John K Ramage and Raj Srirajaskanthan
Type: Article
| 2017
| Item not available on this server.
TAPBPR bridges UDP-glucose: glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway - Andreas Neerincx, Clemens Hermann, Robin Antrobus, Andrew Van Hateren, Huan Cao, Nico Trautwein, Stefan Stevanović, Tim Elliott, Janet E. Deane and Louise H. Boyle
Type: Article
| 2017
p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells - Manikandan Periyasamy, Anup K. Singh, Carolina Gemma, Christian Kranjec, Raed Farzan, Damien A. Leach, Naveenan Navaratnam, Hajnalka L. Pálinkás, Beata G. Vértessy, TR Fenton, John Doorbar, Frances Fuller-Pace, David W. Meek, R. Charles Coombes, Laki Buluwela and Simak Ali
Type: Article
| 2017
| Item not available on this server.
Validation of immune cell modules in multicellular transcriptomic data - Gabriele Pollara, Matthew J Murray, James M Heather, Rachel Byng-Maddick, Naomi Guppy, Matthew Ellis, Carolin T Turner, Benjamin M Chain and Mahdad Noursadeghi
Type: Article
| 2017
Understanding the relationship between the perineuronal net and glia within the auditory pathway in a mouse model of age-related hearing loss - Shmma Quraishe, Genevieve Brixton, Bethan Impey, Edward Rogers, Carl Verschuur and Tracey Newman
Type: Conference or Workshop Item
| 2017
| Item not available on this server.
Type: Review
| 2017
| Item not available on this server.
Type: Other
| 2017
| Item availability restricted.
Clinically significant differences in Ki-67 proliferation index between primary and metastases in resected pancreatic neuroendocrine tumors - Sebastian Richards-Taylor, Charles Tilley, Eleanor Jaynes, Haixiao Hu, Thomas Armstrong, Neil W Pearce, Rachel Plant and Judith Cave
Type: Article
| 2017
| Item not available on this server.
Healthcare professionals’ and patients’ perspectives on consent to clinical genetic testing: moving towards a more relational approach - Gabrielle Samuel, Sandeep Dheensa, Bobbie Farsides, Angela Fenwick and Anneke Lucassen
Type: Article
| 2017
Public trust and ‘ethics review’ as a commodity: the case of Genomics England Limited and the UK’s 100,000 genomes project - Gabrielle Samuel and Bobbie Farsides
Type: Article
| 2017
| Item not available on this server.
The danger of lurking: different conceptualizations of user awareness in social media research - Gabrielle Natalie Samuel
Type: Letter
| 2017
| Item not available on this server.
Phase 1 study of inotuzumab ozogamicin combined with R-GDP for the treatment of patients with relapsed/refractory CD22+ B-cell non-Hodgkin lymphoma - Randeep Sangha, Andrew Davies, Nam H Dang, Michinori Ogura, David A MacDonald, Revathi Ananthakrishnan, M Luisa Paccagnella, Erik Vandendries, Joseph Boni and Yeow Tee Goh
Type: Article
| 2017
Nanog fluctuations in embryonic stem cells highlight the problem of measurement in cell biology - Rosanna Smith, Patrick Stumpf, Sonya Ridden, Aaron Sim, Sarah Filippi, Heather Harrington and Benjamin Macarthur
Type: Article
| 2017
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics - Henriët Springelkamp, Adriana I. Iglesias and Aniket Mishra
Type: Article
| 2017
Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption - Rafal Swiercz, Min Mo, Priyanka Khare, Zita Schneider, Raimund J. Ober and Elizabeth Sally Ward
Type: Article
| 2017
Antibody tumor targeting is enhanced by CD27 agonists through myeloid recruitment - Anna H. Turaj, Khiyam Hussain, Kerry L. Cox, Matthew J.J. Rose-Zerilli, James Testa, Lekh N. Dahal, H.T. Claude Chan, Sonya James, Vikki L. Field, Matthew J. Carter, Hyung J. Kim, Jonathan J. West, Lawrence J. Thomas, Li-Zhen He, Tibor Keler, Peter W.M. Johnson, Aymen Al-Shamkhani, Stephen M. Thirdborough, Stephen A. Beers, Mark S. Cragg, Martin J. Glennie and Sean H. Lim
Type: Article
| 2017
State space approach to single molecule localization in fluorescence microscopy - Milad R. Vahid, Jerry Chao, Dongyoung Kim, E. Sally Ward and Raimund J. Ober
Type: Article
| 2017
| Item not available on this server.
A state space based approach to localizing single molecules from multi-emitter images - Milad R. Vahid, Jerry Chao, E. Sally Ward and Raimund J. Ober
Type: Conference or Workshop Item
| 2017
| SPIE
| Item not available on this server.
Intensity-based axial localization approaches for multifocal plane microscopy - Ramraj Velmurugan, Jerry Chao, Sripad Ram, E. Sally Ward and Raimund J. Ober
Type: Article
| 2017
| Item not available on this server.
Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity - E. Sally Ward and Raimund J. Ober
Type: Article
| 2017
| Item not available on this server.
Development of the EORTC QLQ-CAX24, a questionnaire for cancer patients with cachexia - S.J. Wheelwright, J.B. Hopkinson, A.-S. Darlington, D.F. Fitzsimmons, P. Fayers, T.R. Balstad, A. Bredart, E. Hammerlid, S. Kaasa, O. Nicolatou-Galitis, M. Pinto, H. Schmidt, T.S. Solheim, F. Strasser, I.M. Tomaszewska and C.D. Johnson
Type: Article
| 2017
Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins - Gordana Wutz, Csilla Várnai, Kota Nagasaka, David A Cisneros, Roman R Stocsits, Wen Tang, Stefan Schoenfelder, Gregor Jessberger, Matthias Muhar, M Julius Hossain, Nike Walther, Birgit Koch, Moritz Kueblbeck, Jan Ellenberg, Johannes Zuber, Peter Fraser and Jan‐Michael Peters
Type: Article
| 2017
| Item not available on this server.
Recent advances in Major Histocompatibility Complex (MHC) class I antigen presentation: plastic MHC molecules and TAPBPR-mediated quality control - Andrew van Hateren, Timothy Elliott and Alistair Bailey
Type: Review
| 2017
Direct evidence for conformational dynamics in major histocompatibility complex class I molecules - Andy van Hateren, Malcolm Anderson, Alistair Bailey, Jörn M Werner, Paul Skipp and Tim Elliott
Type: Article
| 2017