Items where Division is "Faculties (pre 2018 reorg) > Faculty of Medicine (pre 2018 reorg) > Clinical & Experimental Sciences (pre 2018 reorg)
Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences > Clinical & Experimental Sciences (pre 2018 reorg)
Clinical and Experimental Sciences > Clinical & Experimental Sciences (pre 2018 reorg)" and Year is 2020
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Number of items: 62.
Femtolaser-assisted keratoplasty: surgical outcomes and benefits - Joshua Adeyoju, Aristides Konstantopoulos, Jodhbir S. Mehta and Parwez Hossain
Type: Article
| 2020
Cohort profile update: the Isle of Wight whole population birth cohort (IOWBC) - Syed Arshad, Veeresh, Keshirajagowda Patil, Frances Mitchell, Stephen Potter, Hongmei Zhang, Susan Ewart, Linda Mansfield, Carina Venter, John Holloway and Wilfried J. Karmaus
Type: Article
| 2020
Characterization of the class I MHC peptidome resulting from DNCB exposure of HaCaT cells - Alistair Bailey, Benjamin Nicholas, Rachel Darley, Erika Parkinson, Ying Teo, Maja Aleksic, Gavin Maxwell, Timothy Elliott, Michael Ardern-Jones and Paul Skipp
Type: Article
| 2020
Comparison of two published definitions of sputum neutrophilia show clinical measures of disease are more severe in neutrophilic asthma (NA) than non-neutrophilic asthma (NNA) using >40% sputum neutrophils as the definition of disease - Clair Barber, Jon Ward, Scott Elliott, Laurie Lau, Adnan Azim, Kerry Gove, Hitasha Rupani, Thomas Brown, Anoop Chauhan, Karl J Staples and Peter H Howarth
Type: Meeting abstract
| 2020
| Item not available on this server.
415. Clinical impact of molecular point-of-care testing for COVID-19 in adults presenting to hospital: a prospective, interventional, non-randomised, controlled study - Nathan J Brendish, Stephen Poole, Vasanth V Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland, Sean Ewings, Stephen P Kidd, Nick Cortes and Tristan William Clark
Type: Article
| 2020
Sleep-disordered breathing and comorbidities: role of the upper airway and craniofacial skeleton - Lucy Charlotte Brennan, Fenella Jane Kirkham and Johanna Cristine Gavlak
Type: Article
| 2020
Time taken from primary care referral to a specialist centre diagnosis of idiopathic pulmonary fibrosis: an opportunity to improve patient outcomes? - Christopher J Brereton, Timothy Wallis, Michelle Casey, Lynn Fox, Katarina Pontoppidan, Diane Laws, Jennifer Graves, Vanessa Titmuss, Sarah Kearney, Sian Louise Evans, Alison Grove, Samreen Hamid, Luca Richeldi, Katherine M.A. O'Reilly, Sophie Fletcher and Mark Glynne Jones
Type: Letter
| 2020
QOL-33. THE PROMOTE STUDY: DEVELOPMENT AND TESTING OF KLIK-UK, AN ONLINE PLATFORM, TO ENHANCE OUTPATIENT COMMUNICATION ABOUT HEALTH-RELATED QUALITY OF LIFE (HRQOL) AT THREE UK CHILDREN’S BRAIN TUMOUR TREATMENT CENTRES (CBTTCs) - Kim Bull, Shelly Stubley, Natalia Kouzoupi, Anne-Sophie Darlington, Martha A. Grootenhuis, Darren R. Hargrave, Christina Liossi, Christopher Morris, David Walker and Colin Kennedy
Type: Meeting abstract
| 2020
| Item not available on this server.
Point-of-care inflammatory phenotyping predicts clinical outcome in COVID-19 - H. Burke, A. Freeman, D.C. Cellura, B.L. Stuart, N.J. Brendish, S. Poole, F. Borca, N. Sheard, S. Williams, C.M. Spalluto, K.J. Staples, T.W. Clark and T. Wilkinson
Type: UNSPECIFIED
| 2020
| Item not available on this server.
QOL-17. Biological correlates of quality of survival and neurocognitive outcomes in medulloblastoma; a meta-analysis of the SIOP-UKCCSG-PNET3 and HIT-SIOP-PNET4 trials - Mathilde Chevignard, Kim Bull, James Holt, Marie-Amelie Heng, Colin Kennedy, Francois Doz, Birgitta Lannering, Stefan Rutkowski, Maura Massimino, Steven Clifford and Debbie Hicks
Type: Meeting abstract
| 2020
Identifying those at risk of reattendance at discharge from emergency departments using explainable machine learning - F. P. Chmiel, M. Azor, F. Borca, M. J. Boniface, D. K. Burns, Z. D. Zlatev, N. M. White, T. W.V. Daniels and M. Kiuber
Type: Article
| 2020
| Item not available on this server.
Clinical impact of a routine, molecular, point-of-care, test-and-treat strategy for influenza in adults admitted to hospital (FluPOC): a multicentre, open-label, randomised controlled trial - Tristan Clark, Kate Beard, Nathan Brendish, Ahalya Malachira, Samuel Mills, Cathleen Chan, Stephen Poole, Sean Ewings, Nicholas Cortes, Esther Nyimbili and Laura Presland
Type: Article
| 2020
Integrating molecular point-of-care testing for influenza into primary care: a mixed-methods feasibility study - Tristan Clark, Simon de Lusignan, Uy Hoang, Harshana Liyanage, Manasa Tripathy, Ivelina Yonova, Rachel Byford, Filipa Ferreira and Javier Diez-Domingo
Type: Article
| 2020
A revised protocol for culture of airway epithelial cells as a diagnostic tool for primary ciliary dyskinesia - Janice Coles, James Thompson, Katie Leanne Horton, Robert A. Hirst, Paul Griffin, Gwyneth Williams, Patricia Goggin, Regan Jean Doherty, Peter Lackie, Amanda Harris, Woolf T. Walker, Christopher O'Callaghan, Claire Hogg, Jane Lucas, Cornelia Blume and Claire Jackson
Type: Article
| 2020
Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis - Franco Conforti, Robert Ridley, Christopher J Brereton, Mark Jones, Donna Davies, Paul Skipp, Yihua Wang, Christian Ottensmeier, Luca Richeldi and Benjamin Johnson
Type: Article
| 2020
The role of Intestinal tissue macrophages in the pathogenesis of Inflammatory Bowel Disease - Suranga Anurada Dharmasiri
Type: Thesis
| 2020
| University of Southampton
Pseudomonas aeruginosa host-pathogen interactions in human corneal infection models - Ahmad Elsahn, Maria del mar DM Cendra gascon, Maria Humbert, Myron Christodoulides, Harminder S Dua and Parwez Hossain
Type: Article
| 2020
Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanisms - Mohammad Asif Emon, Ashley Heinson, Ping Wu, Daniel Domingo-Fernández, Meemansa Sood, Henri A. Vrooman, Jean-Christophe Corvol, Phil Scordis, Martin Hofmann-Apitius and Holger Fröhlich
Type: Article
| 2020
Clinical utility of NGS diagnosis and disease stratification in a multi-ethnic primary ciliary dyskinesia cohort - Mahmoud R. Fassad, Mitali Patel, Amelia Shoemark, Thomas Cullup, Jane Hayward, Mellisa Dixon, Andrew V. Rogers, Sarah Ollosson, Claire Jackson, Patricia Goggin, Robert A. Hirst, Andrew Rutman, James Thompson, Lucy Jenkins, Paul Aurora, Eduardo Mova, Philip Chetcuti, Christopher O'Callaghan, Deborah Morris-Rosendahl, Christopher M. Watson, Robert Wilson, Siobhan Carr, Woolf Walker, Andreia Pinto, Susana P. Lopes, Heba Morsy, Walaa Shoman, Luísa Pereira, Carolina Constant, Michael R. Loebinger, Eddie M.K. Chung, Priti Kenia, Nisreen Rumman, Nader Fasseeh, Jane Lucas, Claire Hogg and Hannah Mitchison
Type: Article
| 2020
MicroRNA23a overexpression in Crohn’s Disease targets Tumour Necrosis Factor Alpha Inhibitor Protein 3, increasing sensitivity to TNF and modifying the epithelial barrier - Richard Felwick, Geraint Dingley, Rocio T. Martinez-Nunez, Tilman Sanchez-Elsner, J.R. Fraser Cummings and Jane Collins
Type: Article
| 2020
The impact of obesity in patients with severe asthma in the Wessex Severe Asthma Cohort (WSAC) - Lauren Fox, Thomas Brown, Laura Wiffen, Thomas Jones, Kerry Gove, Clair Barber, Scott Elliott, Hitasha Rupani, Anoop Chauhan and Peter Howarth
Type: Meeting abstract
| 2020
| Item not available on this server.
Is the strength of the type-2 (T2) inflammatory biomarker signal important in determining the burden of disease in severe asthma (SA)? - Lauren Fox, Thomas Brown, Laura Wiffen, Thomas Jones, Kerry Gove, Clair Barber, Scott Elliott, Hitasha Rupani, Peter Howarth and Anoop Chauhan
Type: Meeting abstract
| 2020
| Item not available on this server.
Microglial motility and morphology in Alzheimer's Disease, and after Aβ42- immunotherapy - Diana Karina Franco Bocanegra
Type: Thesis
| 2020
| University of Southampton
Exercise moderates inflammation in asthma through increased redox buffering capacity - Anna Freeman, David Hill, Doriana Cellura, Cosma Mirella Spalluto, Bernadette Fernandez, Magda Minnion, Helen Moyses, Martin Feelisch, Sandy Jack, Karl J Staples, Mike Grocott and Tom M A Wilkinson
Type: Meeting abstract
| 2020
| Item not available on this server.
Patient perceived barriers to exercise and their clinical associations in difficult asthma - Anna T Freeman, David Hill, Colin Newell, Helen Moyses, Adnan Azim, Deborah Knight, Laura Presland, Matthew Harvey, Hans Michael Haitchi, Alastair Watson, Karl J Staples, Ramesh J Kurukulaaratchy and Tom M A Wilkinson
Type: Article
| 2020
Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis - Diana J. Garay-Baquero, Cory H. White and Naomi F. Walker
Type: Article
| 2020
A protocol for a systematic review and meta-analysis to identify measures of breakthrough pain and evaluate their psychometric properties - Katie Greenfield, Simone Holley, Daniel Eric Schoth, Julie Bayliss, Anna-Karenia Anderson, Satbir Jassal, Dilini Rajapakse, Lorna Katharine Fraser, Christine Mott, Margaret Johnson, Ian Wong, Richard Howard, Emily Harrop and Christina Liossi
Type: Article
| 2020
Label-free and multimodal second harmonic generation light sheet microscopy - Niall Hanrahan, Simon I. R. Lane, Peter Johnson, Konstantinos Bourdakos, Christopher Brereton, Robert A. Ridley, Elizabeth R. Davies, Neveen A. Hosny, Gunnar Spickermann, Robert Forster, Graeme Malcolm, Donna Davies, Mark G. Jones and Sumeet Mahajan
Type: Article
| 2020
Staphylococcus aureus internalisation in mast cells in nasal polyps - characterisation of interactions and potential mechanisms - Stephen Hayes, Timothy Charles Biggs, Simon Patrick Goldie, Philip G. Harries, Andrew Walls, Raymond Allan, Sylvia Pender and Rami Salib
Type: Article
| 2020
Semi-automated Intensity-based Image quality assessment with Gaussian Mixture Models - Elaine Ming Li Ho, Charalambos Rossides, Sylvia Pender, Orestis L. Katsamenis, Peter Lackie and Philipp Schneider
Type: Conference or Workshop Item
| 2020
Modified thin manual Descemet stripping endothelial keratoplasty with air-guided, non-pachymetric donor lenticule dissection: outcomes of graft thickness and complication rate - Parwez Hossain, Aristides Konstantopoulos and David Anderson
Type: Article
| 2020
| Item not available on this server.
Health related quality of life in adult Primary Ciliary Dyskinesia patients in Cyprus: development and validation of the Greek version of the QOL-PCD questionnaire - Phivos Ioannou, Panayiotis Kouis, Maria G Kakkoura, Margarita Kaliva, Aristoula Toliopoulou, Kyriacos Andreou, Laura Behan, Jane Lucas, Viki Pananikolaou, George Charalambous, Nicos Middleton and Panayiotis Yiallouros
Type: Article
| 2020
White matter integrity in Tanzanian children with sickle cell anemia: A diffusion tensor imaging study - Mboka Jacob, Hanne Stotesbury, Jamie M. Kawadler, Winok Lapadaire, Dawn E. Saunders, Raphael Z. Sangeda, Clara Chamba, Ramadhan Kazema, Julie Makani, Fenella J. Kirkham and Chris A. Clark
Type: Article
| 2020
Potential assessment of lung samples by X-ray histology (XRH) during surgery - Elena Konstantinopoulou, Orestis L. Katsamenis, Bethany Broadbent, David Chatelet, Philip J Basford, Ian Haig, William Roche, Aiman Alzetani, Philipp Schneider and Peter Lackie
Type: Conference or Workshop Item
| 2020
| Item availability restricted.
Potential for intraoperative assessment of excised lung samples by X-ray histology - Elena Konstantinopoulou, Orestis L. Katsamenis, David Chatelet, Bethany Broadbent, Philip J Basford, Ian Haig, William Roche, Aiman Alzetani, Philipp Schneider and Peter Lackie
Type: Conference or Workshop Item
| 2020
| Item availability restricted.
Morphological and cytokine profiles as key parameters to distinguish between Gram-negative and Gram-positive bacterial keratitis - Aristides Konstantopoulos, Maria del mar DM Cendra gascon, Michael Tsatos, Myron Christodoulides and Parwez Hossain
Type: Article
| 2020
Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes - Elodie Lespagnol, Sémah Tagougui, Bernadette O. Fernandez, Farid Zerimech, Régis Matran, Patrice Maboudou, Serge Berthoin, Amandine Descat, Isabelle Kim, Mehdi Pawlak-Chaouch, Julien Boissière, Eric Boulanger, Martin Feelisch, Pierre Fontaine and Elsa Heyman
Type: Article
| 2020
Upregulation of epithelial metallothioneins by metal-rich ultrafine particulate matter from an underground railway - Matthew Loxham, Jeongmin Woo, Akul Singhania, Natalie P. Smithers, Alison Yeomans, Graham Packham, Alina-Mariana Crainic, Richard Cook, Flemming R. Cassee, Christopher H. Woelk and Donna Davies
Type: Article
| 2020
Combining models of environment, behavior, and physiology to predict tissue hydrogen and oxygen isotope variance among individual terrestrial animals - Sarah Magozzi, Hannah B. Vander Zanden, Michael B. Wunder, Clive N. Trueman, Kailee Pinney, Dori Peers, Philip E. Dennison, Joshua J. Horns, Çağan H. Şekercioğlu and Gabriel J. Bowen
Type: Article
| 2020
High incidence of glucocorticoid-induced hyperglycaemia in inflammatory bowel disease: metabolic and clinical predictors identified by machine learning - Martin McDonnell, Richard J. Harris, Florina Borca, Tilly Mills, Louise Downey, Suranga Dharmasiri, Mayank Patel, Benjamin Zare, Matt Stammers, Trevor R. Smith, Richard Felwick, J.R. Fraser Cummings, Hang T.T. Phan and Markus Gwiggner
Type: Article
| 2020
Primary ciliary dyskinesia - Vito Mennella, Claire Jackson, Corine Driessens, Katie Leanne Horton and Jane Lucas
Type: Book Section
| 2020
| Elsevier
| Item availability restricted.
High frequency of paediatric facial nerve palsy due to Lyme disease in a geographically endemic region - Alasdair Munro, Robert B. Dorey, Daniel Owens, Duncan Steed, Christina Petridou, Trent Herdman, Christine E Jones, Sanjay Patel, Kate Pryde and Saul Faust
Type: Article
| 2020
Peri-arterial pathways for clearance of α-Synuclein and tau from the brain: implications for the pathogenesis of dementias and for immunotherapy - Jacqui Taryn Nimmo, David Johnston, J.C. Dodart, Matthew MacGregor Sharp, Roy O. Weller, James Nicoll, Ajay Verma and Roxana-Octavia Carare
Type: Article
| 2020
Evidence of homologous recombination as a driver of diversity in Brachyspira pilosicoli - Anish Pandey, Maria Humbert, Myron Christodoulides, Alexandra Charlotte Jackson, Jade Passey, Robert La Ragione, David Hampson and David Cleary
Type: Article
| 2020
Evaluating ceftriaxone 80 mg/kg administration by rapid intravenous infusion-A clinical service evaluation - Sanjay Patel, Helen Green, Jacqueline Gray, Michelle Rutter, Amanda Bevan, Kieran Hand, Christine E Jones and Saul N Faust
Type: Article
| 2020
Type: Dataset
| 2020
| University of Southampton
Type: Thesis
| 2020
| University of Southampton
Identification of proteins associated with development of metastasis from cutaneous squamous cell carcinomas (cSCCs) via proteomic analysis of primary cSCCs - Andrew Shapanis, Chester Lai, Stephen Smith, George Stewart Coltart, Matthew Sommerlad, James Schofield, Erika Parkinson, Paul Skipp and Eugene Healy
Type: Article
| 2020
Proteomic profiling of archived tissue of primary melanoma identifies proteins associated with metastasis - Andrew Shapanis, Chester Lai, Mathew Sommerlad, Erika Parkinson, Eugene Healy and Paul Skipp
Type: Article
| 2020
Noninvasive ventilation for COVID-19-associated acute hypoxaemic respiratory failure: experience from a single centre - Arjjana A. Sivaloganathan, Myra Nasim-Mohi, Michael M. Brown, Nabil Abdul, Alexander Jackson, Sophie V. Fletcher, Sanjay Gupta and Ahilanandan Dushianthan
Type: Letter
| 2020
| Item not available on this server.
Personal hygiene risk factors for contact lens-related microbial keratitis - Anna Stellwagen, Cheryl MacGregor, Roger Kung, Aristides Konstantopoulos and Parwez Hossain
Type: Article
| 2020
High-throughput urinary neopterin-to-creatinine ratio monitoring of systemic inflammation - Charlotte M. Stuart, Elina Zotova, Grielof Koster, Aravinthan Varatharaj, Grace Richardson, Faye R. Cornick, Mark Weal, Tracey A. Newman, Anthony D. Postle and Ian Galea
Type: Article
| 2020
QOL-32. THE PROMOTE STUDY: HEALTH-RELATED QUALITY OF LIFE COMMUNICATION NEEDS OF CHILDREN, ADOLESCENTS, AND THEIR FAMILIES ATTENDING OUTPATIENT CONSULTATIONS AFTER TREATMENT FOR A BRAIN TUMOUR - Shelly Stubley, Anita Freeman, Christina Liossi, Anne-Sophie Darlington, Martha A. Grootenhuis, Darren R. Hargrave, Christopher Morris, David Walker, Colin Kennedy and Kim Bull
Type: Meeting abstract
| 2020
| Item not available on this server.
Psychological stress, cognitive decline and the development of dementia in amnestic mild cognitive impairment - Rebecca Sussams, Wolff Schlotz, Zoe Clough, Jay Amin, Sharon Simpson, Amelia Abbott, Rebecca Beardmore, Richard Sharples, Rachel Raybould, Keeley Brookes, Kevin Morgan, David Culliford and Clive Holmes
Type: Article
| 2020
Improving paediatric antimicrobial stewardship in hospital-based settings; why, where and how? - E. Tanner, A.P.S. Munro, J. Gray, H. Green, M. Rutter, C.E. Jones, S.N. Faust, M. Alderton and S.V. Patel
Type: Article
| 2020
Tectonic descemet stripping endothelial keratoplasty for the management of corneal perforation: A case series - Abdo Karim Tourkmani, Abdus Samad Ansari, Parwez Hossain, Aristides Konstantopoulos and David Anderson
Type: Article
| 2020
| Item availability restricted.
Age dependent changes in synaptic NMDA receptor composition in adult human cortical neurons - Mariana Vargas-Caballero, Chrysia-Maria Pegasiou, Ardalan Zolnourian, Diego Gomez-Nicola, Katrin Deinhardt, James Nicoll, Aminul Ahmed, Girish V. Vajramani, Paul Grundy, Matthijs Verhoog, Huibert Mansvelder, V. Hugh Perry and Diederik Bulters
Type: Article
| 2020
Airway hyperresponsiveness in offspring from mothers with allergic airway inflammation during pregnancy is muscarinic receptor and ADAM33 dependent - Marieke Wandel, Elizabeth Rhiannon Davies, Joanne Freda Carmichael Kelly, Stephen Holgate, Donna Davies and Hans Haitchi
Type: Conference or Workshop Item
| 2020
| Item not available on this server.
Generation of novel trimeric fragments of human SP-A and SP-D after recombinant soluble expression in E. coli - Alastair Watson, Grith L. Sørensen, Uffe Holmskov, Harry J. Whitwell, Jens Madsen and Howard Clark
Type: Article
| 2020
| Item not available on this server.
The impact of maintenance oral corticosteroids (OCS) on disease burden and type-2 inflammatory signal in the Wessex Severe Asthma Cohort (WSAC) - Laura Wiffen, Thomas Brown, Lauren Fox, Thomas Jones, Kerry Gove, Clair Barber, Scott Elliott, Hitasha Rupani, Peter Howarth and Anoop Chauhan
Type: Meeting abstract
| 2020
| Item not available on this server.
The impact of depression in patients with severe asthma (SA) in the Wessex Severe Asthma Cohort (WSAC) - Laura Wiffen, Thomas Brown, Lauren Fox, Thomas Jones, Kerry Gove, Clair Barber, Hitasha Rupani, Scott Elliott, Anoop Chauhan and Peter Howarth
Type: Conference or Workshop Item
| 2020
| Item not available on this server.
Comparisons of early and late presentation to hospital in COVID-19 patients - Sarah Williams, Natasha Sheard, Beth Stuart, Hang T T Phan, Florina Borca, Tom M A Wilkinson, Hannah Burke and Anna Freeman
Type: Article
| 2020