Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences > Southampton Clinical Trials Unit
Cancer Sciences > Southampton Clinical Trials Unit" and Year is 2020
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Number of items: 69.
Article
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 - Cristiana Abbafati, Kaja M. Abbas, Mohsen Abbasi-Kangevari and Paul Lee
Type: Article
| 2020
| Item not available on this server.
Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 - Cristiana Abbafati, Kaja M. Abbas, Mohsen Abbasi-Kangevari, Mohammad Abdollahi and Paul Lee
Type: Article
| 2020
| Item not available on this server.
Multicentre, double-blind, randomised, sham-controlled trial of 10 kHz high- frequency spinal cord stimulation for chronic neuropathic low back pain (MODULATE-LBP): a trial protocol - Adnan Al-Kaisy, Jonathan Royds, Stefano Palmisani, David Pang, Samuel Wesley, Rod Taylor, Andrew Cook, Sam Eldabe, Lance McCracken, Rui Duarte and Jeremy Fairbank
Type: Article
| 2020
The association between nationality and nurse job satisfaction in Saudi Arabian hospitals - Husam Braheem Almansour, Mary Gobbi, Jane Prichard and Sean Ewings
Type: Article
| 2020
The Miami International Evidence-Based Guidelines on Minimally Invasive Pancreas Resection - Horacio Asbun, Alma Louise Moekotte and Frederique Vissers
Type: Article
| 2020
Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital: a prospective, interventional, non-randomised, controlled study (COV-19POC) - Nathan Brendish, Stephen Poole, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland, Stephen Kidd, Nicholas Cortes, Florina Borca, Hang Phan, Gavin Babbage, Benoit Visseaux, Sean Ewings and Tristan Clark
Type: Article
| 2020
| Item availability restricted.
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trial - John Bridgewater, Siân A. Pugh, Tom Maishman, Zina Eminton, Jane M. Mellor, Amy Whitehead, Louise Stanton, Michael Radford, Andrea Corkhill, Gareth Griffiths, Stephen Falk, Juan Valle, Derek O'Reilly, Ajith K. Siriwardena, Joanne Hornbuckle, Myrddin Rees, Timothy Iveson, Tamas Hickish, O. James Garden, David Cunningham, Timothy Maughan and John Primrose
Type: Article
| 2020
Type: Article
| 2020
| Item availability restricted.
Symptom clusters in postchemotherapy neutropenic fever in hematological malignancy: associations among sickness behavior symptom cluster, inflammatory biomarkers of procalcitonin and C-reactive protein, and febrile measures - Choi Wan Chan, Paul Hong Lee, Alex Molassiotis and Harold Kwok Kuen Lee
Type: Article
| 2020
| Item not available on this server.
The diversified defocus profile of the near-work environment and myopia development - Kai Yip Choi, Angela Yuen ting Mok, Chi wai Do, Paul Hong Lee and Henry Ho lung Chan
Type: Article
| 2020
| Item not available on this server.
Clinical impact of a routine, molecular, point-of-care, test-and-treat strategy for influenza in adults admitted to hospital (FluPOC): a multicentre, open-label, randomised controlled trial - Tristan Clark, Kate Beard, Nathan Brendish, Ahalya Malachira, Samuel Mills, Cathleen Chan, Stephen Poole, Sean Ewings, Nicholas Cortes, Esther Nyimbili and Laura Presland
Type: Article
| 2020
| Item availability restricted.
Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19 - Tristan Clark, Nathan Brendish, Stephen Poole, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland and Sean Ewings
Type: Article
| 2020
| Item availability restricted.
Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID) - Simon J Crabb, Gareth Griffiths, Ellice Marwood, Denise Dunkley, Nichola Downs, Karen Martin, Michelle Light, Josh Northey, Sam Wilding, Amy Whitehead, Emily Shaw, Alison J Birtle, Amit Bahl, Tony Elliott, Charlotte Westbury, Santhanam Sundar, Angus Robinson, Satinder Jagdev, Satish Kumar, Claire Rooney, Carolina Salinas-Souza, Christine Stephens, Vincent Khoo and Robert J Jones
Type: Article
| 2020
12‐hr shifts in nursing: Do they remove unproductive time and information loss or do they reduce education and discussion opportunities for nurses? A cross‐sectional study in 12 European countries - Chiara Dall'ora, Peter Griffiths, Talia Emmanuel, Anne Marie Rafferty and Sean Ewings
Type: Article
| 2020
Acalabrutinib in Combination with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone (R-CHOP) as first line therapy for patients with diffuse Large B-Cell Lymphoma (DLBCL): The Accept Phase Ib/II single arm study - Andrew Davies, Josh Caddy, Katy Mercer, Louise Stanton, Thomas E C Cummin, Adam Coleman, Gareth Griffiths and Peter Johnson
Type: Article
| 2020
| Item not available on this server.
A phase 2 open-label study of carboplatin in combination with gemcitabine as a dose-dense schedule in patients with locally advanced or metastatic breast cancer that are resistant to anthracyclines and taxanes - Andrew Davies, Christopher Mansbridge, Peter Simmonds, Nicholas Murray, Louise Stanton, Fay Chinnery, Caroline Archer, Peter Barrett-Lee, Tamas Hickish and Simon Crabb
Type: Article
| 2020
| Item not available on this server.
The global distribution of lymphatic filariasis, 2000–18: a geospatial analysis - Aniruddha Deshpande, Molly K. Miller-Petrie, Kimberly B. Johnson, T. H. Nguyen, E. Hill, Irfan Ullah, Z. Zhang and Paul Lee
Type: Article
| 2020
| Item not available on this server.
Association between time spent on smart devices and change in refractive error: a 1-year prospective observational study among Hong Kong children and adolescents - Chi Wai Do, Lily Y.L. Chan, Andy C.Y. Tse and Paul H. Lee
Type: Article
| 2020
| Item not available on this server.
Optimising and profiling pre-implementation contexts to create and implement a public health network intervention for tackling loneliness - Jaimie Ellis, Rebecca Band, Karina Kinsella, Tara Cheetham-Blake, Elizabeth James, Sean Ewings and Anne Rogers
Type: Article
| 2020
Are long shifts, overtime and staffing levels associated with nurses’ opportunity for educational activities, communication and continuity of care assignments? A cross-sectional study - Talia Emmanuel, Chiara Dall'Ora, Sean Ewings and Peter Griffiths
Type: Article
| 2020
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes - L. Fachal, H. Aschard and J. Beesley
Type: Article
| 2020
Physical activity, mental health and well-being of adults during initial COVID-19 containment strategies: A multi-country cross-sectional analysis - James Faulkner, Wendy J. O’Brien, Bronagh Mcgrane, Daniel Wadsworth, John Batten, Christopher D. Askew, Claire Badenhorst, Erin Byrd, Maura Coulter, Nick Draper, Catherine Elliot, Simon Fryer, Michael J. Hamlin, John Jakeman, Kelly A. Mackintosh, Melitta A. McNarry, Andrew Mitchelmore, John Murphy, Helen Ryan-Stewart, Zoe Saynor, Mia Schaumberg, Keeron Stone, Lee Stoner, Beth Stuart and Danielle Lambrick
Type: Article
| 2020
Effectiveness of nurse-led group CBT for hot flushes and night sweats in women with breast cancer: results of the MENOS4 randomised controlled trial - Deborah Fenlon, Tom Maishman, Laura Day, Jacqueline Nuttall, Carl May, Mary Ellis, James Raftery, Lesley Turner, Jo Fields, Gareth Griffiths and Myra S. Hunter
Type: Article
| 2020
Digital tools for the recruitment and retention of participants in randomised controlled trials: A systematic map - Geoffrey Frampton, Jonathan Shepherd, Karen Pickett, Gareth Griffiths and Jeremy Wyatt
Type: Article
| 2020
| Item not available on this server.
Clinical trials in oncology - Gareth Griffiths
Type: Article
| 2020
AGILE-ACCORD: a randomized, multicentre, seamless, adaptive phase I/II platform study to determine the optimal dose, safety and efficacy of multiple candidate agents for the treatment of COVID-19: a structured summary of a study protocol for a randomised platform trial - Gareth Griffiths, Richard Fitzgerald, Thomas Jaki, Andrea Corkhill, Ellice Marwood, Helen Reynolds, Louise Stanton, Sean Ewings, Susannah Condie, Emma Wrixon, Andrea Norton, Mike Radford, Sara Yeats, Jane Robertson, Rachel Darby-Dowman, Lauren Walker and Saye Khoo
Type: Article
| 2020
Strategies to reduce antibiotic use in women with uncomplicated urinary tract infection in primary care: protocol of a systematic review and meta-analysis including individual patient data - Judith Heinz, Christian Röver, Ghefar Furaijat, Yvonne Kaußner, Eva Hummers-Pradier, Thomas Debray, Alastair Hay, Stefan Heytens, Ingvild Vik, Paul Little, Michael Moore, Beth Stuart, Florian Wagenlehner, Philipp Andreas Kronenberg, Sven Ferry, Tor Monsen, Morten Lindbæk, Tim Friede and Ildikó Gágyor
Type: Article
| 2020
Patient reported outcome measures for Acne: a mixed methods validation study (Acne PROMS) - Samantha Hornsey, Beth Stuart, Ingrid Muller, Alison M. Layton, Leanne Morrison, Jamie King, Karen Thomas, Paul Little and Miriam Santer
Type: Article
| 2020
| Item not available on this server.
‘PDSAFE’ - a multi-dimensional model of falls-rehabilitation for people with Parkinson’s. A mixed methods analysis of therapists’ delivery and experience - S Hulbert, K Chivers-seymour, R Summers, S Lamb, V Goodwin, L Rochester, A Nieuwboer, A Rowsell, S Ewing and A Ashburn
Type: Article
| 2020
| Item not available on this server.
A non-linear optimisation method to extract summary statistics from Kaplan-Meier survival plots using the published P value - Andrew Irvine, Sarah Waise, Edward Green and Beth Stuart
Type: Article
| 2020
| Item not available on this server.
A randomised phase II trial of carboplatin and gemcitabine +/- vandetanib in first line treatment of advanced urothelial cell cancer patients not suitable to receive cisplatin - Robert Jones, Simon Crabb, John Chester, Tony Elliott, Robert Huddart, Alison Birtle, Linda Evans, Jason Lester, Satinder Jagdev, Angela Casbard, Chao Huang, Tracie-Ann Madden and Gareth Griffiths
Type: Article
| 2020
Patient-reported outcome measures for monitoring primary care patients with depression (PROMDEP): study protocol for a randomised controlled trial - Tony Kendrick, Michael Moore, Geraldine Leydon, Beth Stuart, Adam W.A. Geraghty, Guiqing Yao, Glyn Lewis, Gareth Griffiths, Carl May, Rachel Dewar-Haggart, Samantha Williams, Shihua Zhu and Christopher Dowrick
Type: Article
| 2020
Effects of an mHealth brisk walking intervention on increasing physical activity in older people with cognitive frailty: pilot randomized controlled trial - Rick Y.C. Kwan, Deborah Lee, Paul H. Lee, Mimi Tse, Daphne S.K. Cheung, Ladda Thiamwong and Kup Sze Choi
Type: Article
| 2020
| Item not available on this server.
A validation study of the use of smartphones and wrist-worn ActiGraphs to measure physical activity at different levels of intensity and step rates in older people - Rick Yiu Cho Kwan, Justina Yat Wa Liu, Deborah Lee, Choi Yeung Andy Tse and Paul Hong Lee
Type: Article
| 2020
| Item not available on this server.
Type: Article
| 2020
| Item not available on this server.
Supporting patient access to medicines in community palliative care on-line survey of health professionals’ practice, perceived effectiveness and influencing factors - Susan Latter, Natasha Campling, Jacqueline Birtwistle, Alison Richardson, Michael Bennett, Sean Ewings, David Meads and Miriam Santer
Type: Article
| 2020
Crowdsourced smartphone data reveal altered sleep/wake pattern in quarantined Chinese during the COVID-19 outbreak - Paul H. Lee, Jan Marek and Petr Nálevka
Type: Article
| 2020
| Item not available on this server.
Associations between quality of life, psychosocial well-being and health-related behaviors among adolescents in Chinese, Japanese, Taiwanese, Thai and the Filipino populations: a cross-sectional survey - Regina L.T. Lee, Wai Tong Chien, Jason Ligot and Paul H. Lee
Type: Article
| 2020
| Item not available on this server.
A cluster randomized controlled trial of a simplified 5-step handwashing technique versus a conventional 7-step handwashing technique among Chinese students with intellectual disabilities - Regina L.T. Lee, Cynthia Leung, Hong Chen, Paul H. Lee and Stephen W.H. Kwok
Type: Article
| 2020
| Item not available on this server.
Relationship between microbiology of throat swab and clinical course among primary care patients with acute cough: a prospective cohort study - Paul Little, Jose M Ordonez-Mena, Thomas R. Fanshawe, Chris Butler, David Mant, Michael Moore and Beth Stuart
Type: Article
| 2020
Machine learning detection of atrial fibrillation using wearable technology - Mark Lown, Michael Brown, Chloe Brown, Arthur M. Yue, Benoy Shah, Simon Corbett, George Lewith, Beth Stuart, Michael Moore and Paul Little
Type: Article
| 2020
Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 - Rafael Lozano, Nancy Fullman, John Everett Mumford and Paul Lee
Type: Article
| 2020
| Item not available on this server.
Diabetes management during cardiac surgery in the UK: a survey - S. Luthra, K. Salhiyyah, G. Dritsakis, K. I. Thorne, E. Dixon, S. Ohri and R. I. G. Holt
Type: Article
| 2020
Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients - Hayley McKenzie, Tom Maishman, Peter Simmonds, Lorraine Durcan, Diana Eccles and Ellen Copson
Type: Article
| 2020
The effectiveness of acupressure in the management of depressive symptoms and in improving quality of life in older people living in the community: a randomised sham-controlled trial - Alex Molassiotis, Lorna Suen, Claudia Lai, Ben Chan, Karen Hong Yun Wat, Jenny Tang, Kui lung To, Cheung on Leung, Sara Lee, Paul Lee and Wai Tong Chien
Type: Article
| 2020
| Item not available on this server.
Comorbidities and their link with individual health status: a cross-sectional analysis of 23,892 people with knee and hip osteoarthritis from primary care - Paul Muckelt, E.M. Roos, Maria Stokes, S. McDonough, DT Grønne, Sean Ewings and ST Skou
Type: Article
| 2020
Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis - Holger J Schünemann, Matthew Ventresca, Mark Crowther, Matthias Briel, Qi Zhou, Fergus Macbeth, Simon Noble, Gareth Griffiths, David Garcia, Gary H. Lyman, Marcello DiNisio, Alfonso Iorio, Lawrence Mbuagbaw, Ignacio Neumann, Nick Van Es, Melissa Brouwers, Gordon Guyatt, Michael B. Streiff, Maura Marcucci, Tejan Baldeh, Ivan D. Florez, Ozlem Gurunlu Alma, Ziad Solh, Patrick M. Bossuyt, Lara A. Kahale, Walter Ageno, George Bozas, Harry R. Büller, Bernard Lebeau, Ramon Lecumberri, Charles Loprinzi, Robert McBane, Kostandinos Sideras, Anthony Maraveyas, Uwe Pelzer, James Perry, Clara Klerk, Giancarlo Agnelli and Elie A. Akl
Type: Article
| 2020
Moringa oleifera leaf powder for type 2 diabetes: a pilot clinical trial - Lassana Sissoko, Nouhoum Diarra, Ibrahim Nientao, Beth Stuart, Adiaratou Togola, Drissa Diallo and Merlin Willcox
Type: Article
| 2020
| Item not available on this server.
The active brains digital intervention to reduce cognitive decline in older adults: Protocol for a feasibility randomized controlled trial - Kirsten Smith, Katherine Bradbury, Rosie Essery, Sebastien Pollet, Fiona Mowbray, Joanna Slodkowska-Barabasz, James Denison-Day, Victoria Hayter, Joanne Marie Kelly, Jane Somerville, Jin Zhang, Elisabeth B Grey, Max Western, Anne Ferrey, Adele Krusche, Beth Stuart, Nanette Mutrie, Sian Robinson, Lily Guiqing, Gareth Griffiths, Louise Robinson, Martin N. Rossor, John E. Gallacher, Simon J. Griffin, Tony Kendrick, Shanaya Rathod, Bernard Gudgin, Rosemary Phillips, Tom Stokes, John Niven, Paul Little and Lucy Yardley
Type: Article
| 2020
Herbal medicine for acute bronchitis: A qualitative interview study of patients’ and health professionals’ views - Dia Soilemezi, Geraldine Leydon, Ruiyang Yan, Catherine Simpson, Margaret Bell, Jennifer Bostock, Michael Moore and Merlin Willcox
Type: Article
| 2020
| Item not available on this server.
Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials - Beth Stuart, Taeko Becque, Michael Moore and Paul Little
Type: Article
| 2020
Change in modifiable maternal characteristics and behaviours between consecutive pregnancies and offspring adiposity: a systematic review - Elizabeth Taylor, Sam Wilding, Nida Ziauddeen, Keith Godfrey, Ann Berrington and Nisreen Alwan
Type: Article
| 2020
Comparing sleep patterns between children with autism spectrum disorder and children with typical development: a matched case–control study - Andy C.Y. Tse, C. C.W. Yu and Paul H. Lee
Type: Article
| 2020
| Item not available on this server.
An exploration of the effectiveness of a peer-led pain management program (PAP) for nursing home residents with chronic pain and an evaluation of their experiences: a pilot randomized controlled trial - Mimi Tse, Yajie Li, Shuk Kwan Tang, Shamay S.M. Ng, Xue Bai, Paul H. Lee, Raymond Lo and Suey Shuk Yu Yeung
Type: Article
| 2020
| Item not available on this server.
An exploration of the use of visually appealing contexts in a pain management program - Mimi Mun Yee Tse, Shamay S.M. Ng, Xue Bai, Paul Hong Lee, Raymond Lo, Suey Shuk Yu Yeung, Yajie Li and Shuk Kwan Tang
Type: Article
| 2020
| Item not available on this server.
Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide - Mattew Ventresca, Holger J. Schünemann, Fergus Macbeth, Mike Clarke, Lehana Thabane, Gareth Griffiths, Simon Noble, David Garcia, Maura Marcucci, Alfonso Iorio, Qi Zhou, Mark Crowther, Elie A. Akl, Gary H. Lyman, Viktoria Gloy, Marcello DiNisio and Matthias Briel
Type: Article
| 2020
Are environmental area characteristics at birth associated with overweight and obesity in school-aged children? Findings from the SLOPE (Studying Lifecourse Obesity PrEdictors) population-based cohort in the south of England - Sam Wilding, Nida Ziauddeen, Dianna Smith, Paul Roderick, Debbie Chase and Nisreen Alwan
Type: Article
| 2020
Immune reconstitution in children following chemotherapy for Acute Lymphoblastic Leukaemia - Anthony Williams, Jessica Bate, Rachel Brooks, Stuart Clarke, Elizabeth Dixon, Saul Faust, Julia C. Chisholm, Angeliki Galanopoulou, Paul Heath, Thomas Maishman, Susan Mapstone, Soonie R. Patel, Ajay Vora, Sam Wilding and Juliet Gray
Type: Article
| 2020
Comparisons of early and late presentation to hospital in COVID-19 patients - Sarah Williams, Natasha Sheard, Beth Stuart, Hang T T Phan, Florina Borca, Tom M A Wilkinson, Hannah Burke and Anna Freeman
Type: Article
| 2020
Obestatin and growth hormone reveal the interaction of central obesity and other cardiometabolic risk factors of metabolic syndrome - Angus P. Yu, Felix N. Ugwu, Bjorn T. Tam, Paul H. Lee and Parco M. Siu
Type: Article
| 2020
| Item not available on this server.
Prevalence of sleep disturbances during COVID-19 outbreak in an urban Chinese population: a cross-sectional study - Branda Yee Man Yu, Wing Fai Yeung, Jason Chun Sing Lam and Paul Hong Lee
Type: Article
| 2020
| Item not available on this server.
The Khorana score for prediction of venous thromboembolism in cancer patients: an individual patient data meta-analysis - Nick van Es, Matthew Ventresca, Marcello Di Nisio, Qi Zhou, Simon Noble, Mark Crowther, Matthias Briel, David Garcia, Gary H. Lyman, Fergus Macbeth, Gareth Griffiths, Alfonso Iorio, Lawrence Mbuagbaw, Ignacio Neumann, Jan Brozek, Gordon Guyatt, Michael B. Streiff, Tejan Baldeh, Ivan D. Florez, Ozlem Gurunlu Alma, Giancarlo Agnelli, Walter Ageno, Maura Marcucci, George Bozas, Gilbert Zulian, Anthony Maraveyas, Bernard Lebeau, Ramon Lecumberri, Kostandinos Sideras, Charles Loprinzi, Robert McBane, Uwe Pelzer, Hanno Riess, Ziad Solh, James Perry, Lara A. Kahale, Patrick M Bossuyt, Clara Klerk, Harry R. Büller, Elie A. Akl and Holger J. Schünemann
Type: Article
| 2020
Letter
The quality of the reported sample size calculation in clinical trials on COVID-19 patients indexed in PubMed - Paul H. Lee
Type: Letter
| 2020
| Item not available on this server.
Sample sizes in COVID-19–related research - Paul H. Lee
Type: Letter
| 2020
| Item not available on this server.
Review
Do surgical margins matter after mastectomy?: A systematic review - James Bundred, Sarah Michael, Sarah Bowers, Nicola Barnes, Yasmin Jauhari, Dafydd Plant, Thomas Maishman, Ramsey Cutress, Bernd Holleczek, David Dodwell and Nigel Bundred
Type: Review
| 2020
REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial - Tony Kendrick, Adam W.A. Geraghty, Hannah Bowers, Beth Stuart, Geraldine Leydon, Carl May, Guiqing Yao, Wendy O'Brien, Marta Glowacka, Simone Holley, Samantha Williams, Shihua Zhu, Rachel Dewar-Haggart, Bryan Palmer, Margaret Bell, Sue Collinson, Imogen Fry, Glyn Lewis, Gareth Griffiths, Simon Gilbody, Joanna Moncrieff, Michael Moore, Una Macleod, Paul Little and Christopher Dowrick
Type: Review
| 2020
The effect of e-health interventions promoting physical activity in older people: a systematic review and meta-analysis - Rick Yiu Cho Kwan, Dauda Salihu, Paul Hong Lee, Mimi Tse, Daphne Sze Ki Cheung, Inthira Roopsawang and Kup Sze Choi
Type: Review
| 2020
| Item not available on this server.
Meeting abstract
P-222 Analysis of tumour contours and radiotherapy planning of “on-trial” patients undergoing chemoradiotherapy (CRT) in SCALOP trial: does pre-trial Radiotherapy Quality Assurance (RTQA) improve the quality of “on-trial” radiotherapy? - E. Fokas, E. Spezi and N. Patel
Type: Meeting abstract
| 2020
| Item not available on this server.