Items where Division is "Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences
Clinical and Experimental Sciences" and Year is 2022
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Number of items: 56.
A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes - Mahmoud I Abdel-Aziz, Susanne J H Vijverberg, Anne H Neerincx, Paul Brinkman, Ariane H Wagener and John H Riley
Type: Letter
| 2022
| Item availability restricted.
NTHi infection of pulmonary macrophages drives neutrophilic inflammation in severe asthma - Jodie Ackland, Clair Barber, Ashley Heinson, Adnan Azim, David W. Cleary, Myron Christodoulides, Ramesh Kurukulaaratchy, Peter H Howarth, Tom M. A. Wilkinson and Karl J. Staples
Type: Article
| 2022
| Item availability restricted.
Predicting pulmonary function from the analysis of voice: A machine learning approach - Md. Zahangir Alam, Albino Simonetti, Raffaele Brillantino, Nick Tayler, Chris Grainge, Pandula Siribaddana, S. A. Reza Nouraei, James Batchelor, M. Sohel Rahman, Eliane V. Mancuzo, John W. Holloway, Judith A. Holloway and Faisal I. Rezwan
Type: Article
| 2022
An evidence-based surveillance tool to identify and report catheter/cannula bloodstream infection in patients receiving parenteral nutrition - Peter David Austin, Kieran Sean Hand, Jane Macnaughtan, Kordo Saeed, Susan Diane Harding, Caroline Smith and Marinos Elia
Type: Article
| 2022
| Item not available on this server.
Validation and further insight into the International Severe Asthma Registry (ISAR) eosinophil gradient algorithm in the Wessex AsThma CoHort of difficult asthma (WATCH) using historical blood eosinophil counts and induced sputum - Clair Barber, Adnan Azim, Colin Newell, Aref Kyyaly, Hitasha Rupani, Hans Michael Haitchi, Peter Howarth and Ramesh Kurukulaaratchy
Type: Letter
| 2022
Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study - Caroline Barker, Katharine Collet, Diane Gbesemete, Maria Piggin, Daniella Watson, Philippa Pristerà, Wendy Lawrence, Emma Smith, Michael Bahrami-Hessari, Halle Johnson, Katherine Baker, Ambar Qavi, Carmel McGrath, Christopher Chiu, Robert C Read and Helen Ward
Type: Article
| 2022
An international survey on nasal nitric oxide measurement practices for the diagnosis of primary ciliary dyskinesia - Nicole Beydon, T. Ferkol, Amanda Harris, M Colas, Stephanie D. Davis, Eric G. Haarman, Claire Hogg, Emma Kilbride, Panayiotis Kouis, Claudia E. Kuehni, Philipp Latzin, Diana Marangu, June K. Marthin, Kim G. Nielsen, Phil Robinson, Nisreen Rumman, Matthew Rutter, Woolf Walker and Jane Lucas
Type: Article
| 2022
Combined RT-PCR and host response point-of-care testing in patients hospitalised with suspected COVID-19: a prospective diagnostic accuracy study - Nathan Brendish, Alex Tanner, Stephen Poole, Kate Beard, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland and Tristan Clark
Type: Article
| 2022
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis - Christopher, J Brereton, Liudi Yao, Elizabeth R. Davies, Yilu Zhou, Milica Vukmirovic, Joseph Bell, Siyuan Wang, Robert Ridley, Lareb Dean, Orestis Andriotis, Franco Conforti, Lennart Brewitz, Soran Mohammed, Timothy Wallis, Ali Tavassoli, Robert Ewing, Aiman Alzetani, Benjamin Marshall, Sophie V. Fletcher, P.J. Thurner, Aurelie Fabre, Naftali Kaminski, Luca Richeldi, Atul Bhaskar, Christopher J. Schofield, Matthew Loxham, Donna Davies, Yihua Wang and Mark Jones
Type: Article
| 2022
| Item availability restricted.
Are there disparities in the location of automated external defibrillators in England? - Terry P. Brown, Gavin D. Perkins, Christopher M. Smith, Charles D. Deakin and Rachael Fothergill
Type: Article
| 2022
Biomarker identification using dynamic time warping analysis: a longitudinal cohort study of patients with COVID-19 in a UK tertiary hospital - Hannah Burke, Anna Freeman, Paul O'Regan, Oskar Wysocki, Andre Freitas, Ahilanandan Dushianthan, Michael Celinski, James Batchelor, Hang Phan, Florina Borca, Natasha Sheard, Sarah Williams, Alastair Watson, Paul Fitzpatrick, Dónal Landers and Tom Wilkinson
Type: Article
| 2022
Issues affecting supply of palliative medicines into community pharmacy: A qualitative study of community pharmacist and pharmaceutical wholesaler/distributor perspectives - Natasha Campling, Liz Breen, Elizabeth Miller, Jacqueline Birtwistle, Alison Richardson, Michael Bennett and Susan Latter
Type: Article
| 2022
Immunocompromised children and young people are at no increased risk of severe COVID-19 - H. Chappell, R. Patel, C. Driessens, A.W. Tarr, W.l. Irving, P.J. Tighe, H.J. Jackson, T. Harvey-cowlishaw, L. Mills, M. Shaunak, D. Gbesemete, A. Leahy, J.S. Lucas, S.N. Faust and H. De Graaf
Type: Article
| 2022
Prevalence of depressive disorders and associated demographic characteristics in Shandong: An epidemiological investigation - Xiaojing Cheng, Qian Wang, Ruzhan Wang, Yanhu Wang, Xiuzhe Chen, Guolin Mi, Xu Chen, Lina Wang, Can Wang, Lili Hu, Lingxi Gu, Jingxuan Zhang and Ruihua Hou
Type: Article
| 2022
| Item availability restricted.
Severe COVID‐19 pneumonia in an intensive care setting and comparisons with historic severe viral pneumonia due to other viruses - Kiran Dadhwal, Rosalind Stonham, Hannah Breen, Stephen Poole, Kordo Saeed and Ahilanandan Dushianthan
Type: Article
| 2022
Lactamica 7 Clinical Study Protocol V3.0, 04.10.2019: Defining the immune response to nasopharyngeal colonisation by the commensal Neisseria lactamica - Adam Dale, Anastasia, A Theodosiou, Diane, Frances Gbesemete, Jay Laver, Andrew Vaughan, Marta Polak, Paul Langford, Bidmos Fadil and Robert Read
Type: Monograph
| 2022
| University of Southampton
Type: Dataset
| 2022
| University of Southampton
Association of prenatal acetaminophen use and acetaminophen metabolites with DNA methylation of newborns: analysis of two consecutive generations of the Isle of Wight birth cohort - Shakiba Eslamimehr, A Daniel Jones, Thilani M Anthony, S Hasan Arshad, John W Holloway, Susan Ewart, Rui Luo, Nandini Mukherjee, Parnian Kheirkhah Rahimabad, Su Chen and Wilfried Karmaus
Type: Article
| 2022
Lactamica 3 Clinical Study Protocol V5.0, 26.04.2017: A human controlled infection study to assess colonisation and immunogenicity following nasal inoculation with Neisseria lactamica with eradication on day 4 or 14 - Saul Faust, Diane, Frances Gbesemete, Hans De Graaf and Robert Read
Type: Monograph
| 2022
| University of Southampton
Blood cytokine profiles - Potential biomarkers for asthma persistence into adulthood? - Wei Chern Gavin Fong, Latha Kadalayil, Laurie Lau, Ramesh J Kurukulaaratchy and Syed Hasan Arshad
Type: Letter
| 2022
| Item availability restricted.
Wave comparisons of clinical characteristics and outcomes of COVID-19 admissions - Exploring the impact of treatment and strain dynamics - Anna Freeman, Alastair Watson, Paul O'Regan, Oskar Wysocki, Hannah Burke, Andre Freitas, Robert Livingstone, Ahilanadan Dushianthan, Michael Celinski, James Batchelor, Hang Phan, Florina Borca, Paul Fitzpatrick, Donal Landers and Tom MA Wilkinson
Type: Article
| 2022
Genome-wide association study of clinical outcome after aneurysmal subarachnoid haemorrhage: protocol - Ben Gaastra, Sheila Alexander, Mark K. Bakker, Hemant Bhagat, Philippe Bijlenga, Spiros Blackburn, Malie K. Collins, Sylvain Doré, Christoph Griessenauer, Philipp Hendrix, Eun Pyo Hong, Isabel C. Hostettler, Henry Houlden, Koji IIhara, Jin Pyeong Jeon, Bong Jun Kim, Munish Kumar, Sandrine Morel, Paul Nyquist, Dianxu Ren, Ynte M. Ruigrok, David Werring, Ian Galea, Diederik Bulters and Will Tapper
Type: Article
| 2022
Auditory outcome following aneurysmal subarachnoid haemorrhage - Benjamin Gaastra, Monica Ashokumar, Diederik Bulters, Nicole Campbell and Ian Galea
Type: Article
| 2022
| Item availability restricted.
Microglia and astrocyte function and communication: what do we know in humans? - Emma Garland, Iain Hartnell and Delphine Boche
Type: Review
| 2022
The roles of eosinophils and interleukin-5 in the pathophysiology of chronic rhinosinusitis with nasal polyps - Philippe Gevaert, Joseph K. Han, Steven G. Smith, Ana R Sousa, Peter H. Howarth, Steven W Yancey, Robert Chan and Claus Bachert
Type: Review
| 2022
| Item availability restricted.
International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease - R A Gladstone, L Siira and O B Brynildsrud
Type: Article
| 2022
Modelling wheezing spells identifies phenotypes with different outcomes and genetic associates - Sadia Haider, Raquel Granell, John Curtin, Sara Fontanella, Alex Cucco, Stephen Turner, Angela Simpson, Graham Roberts, Clare S Murray, John W Holloway, Graham Devereux, Paul Cullinan, Syed Hasan Arshad and Adnan Custovic
Type: Article
| 2022
| Item availability restricted.
Brief Report: intravenous fluid prescribing and complications in children in the UK and Ireland - Wesley Hayes, Andrew Marshall, Alastair Sutcliffe, Mark Peters and Katrina Cathie
Type: Article
| 2022
| Item not available on this server.
A capaciflector provides continuous and accurate respiratory rate monitoring for patients at rest and during exercise - Nick Hayward, Mahdi Shaban, James Badger, Isobel Jones, Yang Wei, Daniel Spencer, Stefania Isichei, Martin Knight, James Otto, Gurinder Rayat, Denny Levett, Michael Grocott, Harry Akerman and Neil White
Type: Article
| 2022
Dietary nitrate supplementation does not alter exercise efficiency at high altitude - further results from the Xtreme Alps Study - Philip J. Hennis, Andrew F. Cumpstey, Alasdair F O'Doherty and Monty G Mythen
Type: Article
| 2022
Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort - Uruj Hoda, Stelios Pavlidis, Aruna T Bansal, Kentaro Takahashi, Sile Hu, Francois Ng Kee Kwong and Kian Fan Chung
Type: Article
| 2022
A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries - Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie and Christopher Mccormick
Type: Article
| 2022
| Item availability restricted.
Nonlinear effects of environment on childhood asthma susceptibility - Dilini M. Kothalawala, Veronique B. N. Weiss, Latha Kadalayil, Raquel Granell, John A. Curtin, Clare S. Murray, Angela Simpson, Adnan Custovic, William J. Tapper, Faisal I. Rezwan, Syed Hasan Arshad and John W. Holloway
Type: Letter
| 2022
| Item availability restricted.
MicroRNAs - a promising tool for asthma diagnosis and severity assessment: a systematic review - Mohammed Aref Kyyaly, Elena Vladimirovna Vorobeva, Dilini M Kothalawala, Wei Chern Gavin Fong, Peijun He, Collin L Sones, Mohammad Al-Zahrani, Tilman Sanchez-Elsner, Syed Hasan Arshad and Ramesh J Kurukulaaratchy
Type: Article
| 2022
Recombinant guanosine-5′-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection - Daniela P. Lage, Amanda S. Machado, Danniele L. Vale, Camila S. Freitas, Flávia P. Linhares, Jamille M.O. Cardoso, Isabela A.G. Pereira, Fernanda F. Ramos, Grasiele S.V. Tavares, Fernanda Ludolf, João A. Oliveira-da-Silva, Raquel S. Bandeira, Alessandra M. Silva, Luciana C. Simões, Thiago A.R. Reis, Jamil S. Oliveira, Myron Christodoulides, Miguel A. Chávez-Fumagalli, Bruno M. Roatt, Vívian T. Martins and Eduardo A.F. Coelho
Type: Article
| 2022
| Item availability restricted.
Temporal whole-transcriptomic analysis of characterized in vitro and ex vivo primary nasal epithelia - Jelmer Legebeke, Katie Leanne Horton, Claire Jackson, Janice Coles, Amanda Harris, Htoo Wai, John Holloway, Gabrielle Wheway, Diana Baralle and Jane Lucas
Type: Article
| 2022
Evaluating the immune response in treatment-naïve hospitalised patients with influenza and COVID-19 - Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F Vallejo, Stephen Poole, Nathan Brendish, Xiaofeng Dong, Catherine Hartley, John Holloway, Jane Lucas, Anthony Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P R Schofield, Paul Skipp, Julian A. Hiscox, Marta Polak, Tristan Clark and Diana Baralle
Type: Article
| 2022
| Item availability restricted.
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: three month analyses of the COV-BOOST trial - Xinxue Liu, Alasdair P S Munro, Shuo Feng, Leila Janani, Parvinder K Aley, Gavin Babbage, Katrina Cathie, Daniel R Owens, Robert C Read and Saul N Faust
Type: Article
| 2022
Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19 - Robert Livingstone, Hlaing Lin, Nathan Brendish, Stephen Poole, Florina Borca, Alex Tanner, Trevor Smith, Matt Stammers and Tristan Clark
Type: Article
| 2022
| Item availability restricted.
FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department - Christopher Mansbridge, Alex Tanner, Kate Beard, Florina Borca, Hang Thi Thu Phan, Nathan Brendish, Stephen Poole, Christopher Hill, Michael Kuber, Robert Crouch, Waddington Daniel and Tristan Clark
Type: Article
| 2022
| Item availability restricted.
The FEED1 trial: protocol for a randomised controlled trial of full milk feeds versus intravenous fluids with gradual feeding for preterm infants (30–33 weeks gestational age) - Eleanor J. Mitchell, Garry Meakin, Josie Anderson, Jon Dorling, Chris Gale, Rachel Haines, Charlotte Kenyan, Mark J. Johnson, William McGuire, Hema Mistry, Alan Montgomery, Sam Oddie, Reuben Ogollah, Phoebe Pallotti, Christopher Partlett, Kate F. Walker and Shalini Ojha
Type: Article
| 2022
Mid-regional proadrenomedullin (MR-proADM), C-reactive protein (CRP) and other biomarkers in the early identification of disease progression in patients with COVID-19 in the acute NHS setting - Nathan Moore, Rebecca Williams, Matilde Mori, Beatrice Bertolusso, Gabrielle Vernet, Jessica Lynch, Pete Philipson, Thomas Ledgerwood, Stephen P Kidd, Claire Thomas, Veronica Garcia-Arias, Michelle Young, Kordo Saeed, Kirsty Gordon and Nicholas Cortes
Type: Article
| 2022
| Item availability restricted.
Generation of a cone photoreceptor-specific GNGT2 reporter line in human pluripotent stem cells - Liliya Nazlamova, Emma Jane Cassidy, Jane C. Sowden, Andrew Lotery and Jörn Lakowski
Type: Article
| 2022
| Item availability restricted.
A discrete choice experiment exploring women’s preferences in a novel device designed to monitor the womb environment and improve our understanding of reproductive disorders - Ka Ng, Rhiannon Evans, Hywel Morgan, Emmanouil Mentzakis and Ying Cheong
Type: Conference or Workshop Item
| 2022
Type: Dataset
| 2022
| University of Southampton
Type: Dataset
| 2022
| University of Southampton
Point-of-care testing in Paediatric settings in the UK and Ireland: a cross-sectional study - Meenu Pandey, Mark D Lyttle, Katrina Cathie, Alasdair Munro, Thomas Waterfield and Damian Roland
Type: Article
| 2022
Vulnerability to acid reflux of the airway epithelium in severe asthma - Jeanne-Marie Perotin, Gabrielle Wheway, Kamran Tariq, Adnan Azim, Robert A Ridley, Jonathan A Ward, James Pr Schofield, Clair Barber, Peter Howarth, Donna E Davies and Ratko Djukanovic
Type: Article
| 2022
| Item availability restricted.
Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation - Maria Sparreman Mikus, Johan Kolmert, Lars I Andersson, Jörgen Östling, Richard G Knowles and Cristina Gómez
Type: Article
| 2022
Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves - Olivia V. Swann, Louisa Pollock, Karl A. Holden, Alasdair P.S. Munro, Aisleen Bennett, Thomas C. Williams and Malcolm G. Semple
Type: Article
| 2022
Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1 - Ana Valencia, Candelaria Vergara, Chloe L Thio, Nicolas Vince, Venceslas Douillard, Alba Grifoni, Andrea L Cox, Eric O Johnson, Alex H Kral, James J Goedert, Alessandra Mangia, Valeria Piazzolla, Shruti H Mehta, Gregory D Kirk, Arthur Y Kim, Georg M Lauer, Raymond T Chung, Jennifer C Price, Salim I Khakoo, Laurent Alric, Matthew E Cramp, Sharyne M Donfield, Brian R Edlin, Michael P Busch, Graeme Alexander, Hugo R Rosen, Edward L Murphy, Genevieve L Wojcik, Mary Carrington, Pierre-Antoine Gourraud, Alessandro Sette, David L Thomas and Priya Duggal
Type: Article
| 2022
| Item availability restricted.
Temporal progression of mediastinal lymphadenopathy in idiopathic pulmonary fibrosis - Timothy Wallis, Eyjolfur Gudmundsson, Katarina Pontopiddan, Nesrin Mogulkoc, Katharine Vedwan, Fiona Thompson, Christopher, J Brereton, Benjamin Marshall, Sophie V. Fletcher, Luca Richeldi, Joseph Jacob and Mark Jones
Type: Letter
| 2022
Digital healthcare in COPD management: a narrative review on the advantages, pitfalls, and need for further research - Alastair Watson and Tom M.A. Wilkinson
Type: Review
| 2022
Multi-excitation Raman spectroscopy for label-free, strain-level characterization of bacterial pathogens in artificial sputum media - Jeremy Webb, Adam Lister, Callum Highmore, Niall Hanrahan, James, Arthur Read, Alasdair, Peter Stuart Munro, Samuel Tan, Raymond Allan, Saul Faust and Sumeet Mahajan
Type: Article
| 2022
| Item availability restricted.
Impacted fetal head during second stage Caesarean birth: a prospective observational study - Nia Wyn Jones, Eleanor J. Mitchell, Natalie Wakefield, Marian Knight, Jon Dorling, Jim G. Thornton and Kate F. Walker
Type: Article
| 2022
Optimising growth in very preterm infants: reviewing the evidence - Aneurin Young, R Mark Beattie and Mark John Johnson
Type: Article
| 2022
| Item availability restricted.