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Items where Division is "Faculties (pre 2011 reorg) > Faculty of Medicine Health & Life Sciences (pre 2011 reorg) > Medicine (pre 2011 reorg) > Infection Inflammation & Immunity (pre 2011 reorg)
Faculties (pre 2018 reorg) > Faculty of Medicine (pre 2018 reorg) > Medicine (pre 2011 reorg) > Infection Inflammation & Immunity (pre 2011 reorg)" and Year is 2010

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Number of items: 84.

A

Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children - Rachel S. Agbeko, John W. Holloway, Meredith L. Allen, Shu Ye, Katy J. Fidler, John Pappachan, Allan Goldman, David Pontefract, John Deanfield, Nigel J. Klein and Mark J. Peters
Type: Article | 2010 | Item not available on this server.

Skin manifestations of drug allergy - Michael R. Ardern-Jones and Peter S. Friedmann
Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item not available on this server.

An integrative systems biology approach to understanding pulmonary diseases - Charles Auffray, Ian M. Adcock, Kian Fan Chung, Ratko Djukanovic, Christophe Pison and Peer J. Sterk
Type: Article | 2010 | Item not available on this server.

B

Regulating the genome surveillance system: miRNAs and the p53 super family - Sarah G. Bailey, Tilman Sanchez-Elsner, Anastasis Stephanou, Mark S. Cragg and Paul A. Townsend
Type: Article | 2010 | Item not available on this server.

Reversal of methylprednisolone effects in allergen-exposed female BALB/c mice - David Bassett, Fusao Hirata, Xiufeng Gao, Rangaramanujam Kannan, Janet Kerr, Nicole Doyon-Reale, Susan Wilson and Mary Lieh-Lai
Type: Article | 2010 | Item not available on this server.

Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice - Valerie Besnard, Yohei Matsuzaki, Jean Clark Clark, Yan Xu, Susan E. Wert, Machiko Ikegami, Mildred T. Stahlman, Timothy E. Weaver, Alan N. Hunt, Anthony D. Postle and Jeffrey A. Whitsett
Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item availability restricted.

C

Type: Article | 2010 | Item not available on this server.

Type: Book Section | 2010 | Twelfth International Symposium on Human Chlamydial Infections | Item not available on this server.

Type: Article | 2010 | Item availability restricted.

Management of nut allergy influences quality of life and anxiety in children and their mothers - Amanda J. Cummings, Rebecca C. Knibb, Michel Erlewyn-Lajeunesse, Rosemary M. King, Graham Roberts and Jane S.A. Lucas
Type: Article | 2010 | Item availability restricted.

D

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus - John DeVincenzo, Robert Lambkin-Williams, Tom M.A. Wilkinson, Jeffrey Cehelsky, Sara Nochur, Edward Walsh, Rachel Meyers, Jared Gollob and Akshay Vaishnaw
Type: Article | 2010 | Item not available on this server.

Viral load drives disease in humans experimentally infected with respiratory syncytial virus - John P. DeVincenzo, Tom M.A. Wilkinson, Akshay Vaishnaw, Jeff Cehelsky, Rachel Meyers, Saraswathy Nochur, Lisa Harrison, Patricia Meeking, Alex Mann, Elizabeth Moane, John Oxford, Rajat Pareek, Ryves Moore, Ed Walsh, Robert Studholme, Preston Dorsett, Rene Alvarez and Robert Lambkin-Williams
Type: Article | 2010 | Item not available on this server.

Montelukast added to fluticasone propionate does not alter inflammation or outcomes - Ratko Djukanović, Susan J. Wilson, Wendy C. Moore, Steven M. Koenig, Michel Laviolette, Eugene Bleecker, W. Bruce Davis, Dennis E. Doherty, Ronald Olivenstein, Elliot Israel, Mani Kavuru, Eric Kleerup, Donna S. Reilly, Steven Yancey, Lisa D. Edwards, John L. Stauffer, Paul M. Dorinsky and Nizar N. Jarjour
Type: Article | 2010

E

Type: Article | 2010 | Item not available on this server.

Polymorphisms in PARP, IL1B, IL4, IL10, C11NH, DEFB1 and DEFA4 in meningococcal disease in three populations. - Marieke Emonts, Clementien L. Vermont, J.J. Howing-Duistermaat, Elene Haralambous, Christa E. Gaast-de Jongh, Jan A. Hazelzet, Saul N. Faust, Helen Betts, Peter W.M. Hermans, Michael Levin and Ronald de Groot
Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item not available on this server.

F

Stem cell marker TRA-1-60 is expressed in foetal and adult kidney and upregulated in tubulo-interstitial disease - Irina Fesenko, Danielle Franklin, Paul Garnett, Paul Bass, Sara Campbell, Michelle Hardyman, David Wilson, Neil Hanley and Jane Collins
Type: Article | 2010 | Item not available on this server.

Patch testing in drug allergy - Peter S. Friedmann and Michael R. Ardern-Jones
Type: Article | 2010 | Item not available on this server.

Drug-induced exanthemata: a source of clinical and intellectual confusion - Peter Simon Friedmann, Christopher Pickard, Michael Ardern-Jones and Andreas J. Bircher
Type: Article | 2010 | Item not available on this server.

G

Nitric oxide is not involved in Neisseria gonorrhoeae-induced cellular damage of human fallopian tubes in vitro - Katherine Garcia, Paulina S. Rubilar, Macarena F. Vargas, Hugo Cardenas, Miguel A. Rios, Pedro A. Orihuela, Renato H. Vargas, Juan Fuhrer, John E. Heckels, Myron Christodoulides and Luis A. Velasquez
Type: Article | 2010 | Item availability restricted.

Furosemide in the treatment of phosgene induced acute lung injury - C. Grainge, A.J. Smith, B.J. Jugg, S.J. Fairhall, T. Mann, R. Perrott, J. Jenner, T.M. Millar and P. Rice
Type: Article | 2010 | Item not available on this server.

Characterisation of community and hospital Staphylococcus aureus isolates in Southampton, UK - Steve M. Green, Peter Marsh, Nusreen Ahmad, Johanna M.C. Jefferies and Stuart C. Clarke
Type: Article | 2010 | Item not available on this server.

H

Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease - Tillie-Louise Hackett, Marco Scarci, Lu Zheng, Wan Tan, Tom Treasure and Jane A. Warner
Type: Article | 2010

Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item not available on this server.

Atopy susceptibility and chromosome 19q13 - J.W. Holloway, S.J. Barton and I. Sayers
Type: Article | 2010 | Item not available on this server.

Using genetics to predict the natural history of asthma? - John W. Holloway, Syed H. Arshad and Stephen T. Holgate
Type: Article | 2010 | Item not available on this server.

Type: Thesis | 2010

Crystallization and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael acceptor inhibitor - R.J. Hussey, L. Coates, R.S. Gill, J. Neville Wright, M. Sarwar, S. Coker, P.T. Erskine, J.B. Cooper, S.P. Wood, I.N. Clarke, P.R. Lambden, R. Broadbridge and P.M. Shoolingin-Jordan
Type: Article | 2010 | Item not available on this server.

A structural study of norovirus 3C protease specificity: Binding of a designed active site-directed peptide inhibitor - Robert J. Hussey, Leighton Coates, Raj S. Gill, Peter T. Erskine, Shu-Fen Coker, Ed Mitchell, Jonathan B. Cooper, Steve Wood, Robert Broadbridge, Ian N. Clarke, Paul R. Lambden and Peter M. Shoolingin-Jordan
Type: Article | 2010 | Item not available on this server.

J

Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item availability restricted.

Identification of novel pneumolysin alleles from paediatric carriage isolates of Streptococcus pneumoniae - J.M.C. Jefferies, A.S. Tocheva, H. Rubery, J. Bennett, Joanna Garland, Myron Christodoulides, S.N. Faust, A.G. Smith, T.J. Mitchell and S.C. Clarke
Type: Article | 2010 | Item not available on this server.

Type: Article | 2010

K

The multinational birth cohort of EuroPrevall: background, aims and methods. - T. Keil, D. McBride, K. Grimshaw, B. Niggemann, P. Xepapadaki, K. Zannikos, S.T. Sigurdardottir, M. Clausen, M. Reche, C. Pascual, A.P. Stanczyk, M.L. Kowalski, R. Dubakiene, G. Drasutiene, G. Roberts, A.F.A. Schoemaker, A.B. Sprikkelman, A. Fiocchi, A. Martelli, S. Dufour, J. Hourihane, M. Kulig, M. Wjst, M. Yazdanbakhsh, Z. Szépfalusi, R. Van Ree, S.N. Willich, U. Wahn, E.N.C. Mills and K. Beyer
Type: Article | 2010 | Item not available on this server.

Differential expression of claudin tight junction proteins in the human cortical nephron - Adam Kirk, Sara Campbell, Paul Bass, Juan Mason and Jane Collins
Type: Article | 2010 | Item not available on this server.

In-vivo quantification of bacterial keratitis with optical coherence tomography - Aris Konstantopoulos, Marina Fievez, David Anderson and Parwez Hossain
Type: Article | 2010 | Item availability restricted.

Factors influencing age at diagnosis of primary ciliary dyskinesia in European children - C. E. Kuehni, T. Frischer, M-P.F. Strippoli, E. Maurer, Andrew Bush, K.G. Nielsen, A. Escribano, J.S.A. Lucas, P. Yiallouros, H. Omran, E. Eber, C. O'Callaghan, D. Snijders and A. Barbato
Type: Article | 2010 | Item not available on this server.

Neuropeptide alpha-MSH exerts pro-inflammatory effects on Neisseria meningitidis infection in vitro - Pawan Kumar, Jeannette N. Williams, Kesta L. Durkin, John E. Heckels, Peter S. Friedmann, Eugene Healy and Myron Christodoulides
Type: Article | 2010 | Item not available on this server.

L

Continuous versus on-demand pharmacotherapy of allergic rhinitis: evidence and practice - Gert Laekeman, Steven Simoens, Johan Buffels, Michel Gillard, Thibert Robillard, Margherita Strolin Benedetti, Jean-Baptiste Watelet, Georges Liekendael and Martin K. Church
Type: Article | 2010 | Item not available on this server.

Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener’s granulomatosis as compared to rheumatoid arthritis and chronic rhinosinusitis with nasal polyps - M. Laudien, S.D. Gadola, R. Podschun, J. Hedderich, J. Paulsen, E. Reinhold-Keller, E. Csernok, P. Ambrosch, B. Hellmich, F. Moosig, W. Gross, H. Sahly and P. Lamprecht
Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item not available on this server.

Elevation of sputum matrix metalloproteinase-9 persists up to 6 months after smoking cessation: a research study - Noora Louhelainen, Harri Stark, Witold Mazur, Paula Rytilä, Ratko Djukanovic and Vuokko L. Kinnula
Type: Article | 2010 | Item not available on this server.

M

Gp-340/DMBT1 in mucosal innate immunity - J. Madsen, J. Mollenhauer and U. Holmskov
Type: Article | 2010 | Item not available on this server.

Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes - Juraj Majtan, Pawan Kumar, Tomas Majtan, Andrew F. Walls and Jaroslav Klaudiny
Type: Article | 2010 | Item not available on this server.

Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop - Gediminas Matulis, Joseph P. Sanderson, Nikolai M. Lissin, Maria B. Asparuhova, Gopal R. Bommineni, Daniel Schumperli, Richard R. Schmidt, Peter M. Villiger, Bent K. Jakobsen and Stephan D. Gadola
Type: Article | 2010

Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema - T. McPherson, V. J. Sherman, A. Aslam, L. Crack, H. Chan, A. Lloyd-Lavery, L.E. Jones, M Ardern-Jones and G. Ogg
Type: Article | 2010 | Item not available on this server.

A panel of antibodies for identifying squamous metaplasia in endobronchial biopsies from smokers - J. Merryfield, R. O'Donnell, Donna E. Davies, Ratko Djukanovic and Susan J. Wilson
Type: Article | 2010 | Item not available on this server.

Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data - Cosetta Minelli, Raquel Granell, Roger Newson, Matthew J. Rose-Zerilli, Maties Torrent, Sue M. Ring, John W. Holloway, Seif O. Shaheen and John A. Henderson
Type: Article | 2010

How do teenagers manage their food allergies? - H. Monks, M.H. Gowland, H. MacKenzie, M. Erlewyn-Lajeunesse, R. King, J.S. Lucas and G. Roberts
Type: Article | 2010 | Item not available on this server.

N

Glucocorticoids inhibit IL-1beta-induced GM-CSF expression at multiple levels: roles for the ERK pathway and repression by MKP-1 - Robert Newton, Elizabeth M. King, Wei Gong, Christopher F. Rider, K arl J. Staples, Neil S. Holden and Martin W. Bergmann
Type: Article | 2010 | Item not available on this server.

Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease - Benjamin L. Nicholas, Paul Skipp, Sheila Barton, Dave Singh, Dinesh Bagmane, Richard Mould, Gilbert Angco, Jon Ward, Binita Guha-Niyogi, Susan Wilson, Peter Howarth, Donna E. Davies, Stephen Rennard, C. David O'Connor and Ratko Djukanovic
Type: Article | 2010 | Item not available on this server.

O

Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study - Ikechukwu U. Ogbuanu, Wilfried J. Karmaus, Hongmei Zhang, Tara Sabo-Attwood, Susan Ewart, Graham Roberts and Syed Hasan Arshad
Type: Article | 2010 | Item not available on this server.

P

Patterns of fetal and infant growth are related to atopy and wheezing disorders at age 3 years - Katharine P. Pike, Sarah R. Crozier, Jane S.A. Lucas, Hazel M. Inskip, Sian Robinson, Graham Roberts and Keith M. Godfrey
Type: Article | 2010 | Item availability restricted.

Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1 - Tracey L. Purvis, Tom Hearn, Cosma Spalluto, Victoria J. Knorz, Karen Piper Hanley, Tilman Sanchez-Elsner, Neil A. Hanley and David I. Wilson
Type: Article | 2010 | Item not available on this server.

Osteopontin is expressed and functional in human eosinophils - I. Puxeddu, D. Berkman, R. Ribatti, H. Bader, H.M. Haitchi, D.E. Davies, P.H. Howarth and F. Levi-Schaffer
Type: Article | 2010 | Item not available on this server.

R

Genome-wide association study identifies five loci associated with lung function - E. Repapi, I. Sayers, L.V. Wain, P.R. Burton, T. Johnson, M. Obeidat, J.H. Zhao, A. Ramasamy, G. Zhai, V. Vitart, J.E. Huffman, W. Igl, E. Albrecht, P. Deloukas, J. Henderson, R. Granell, W.L. McArdle, A.R. Rudnicka, I. Barroso, R.J.F. Loos, N.J. Wareham, L. Mustelin, T. Rantanen, I. Surakka, M. Imboden, H.E. Wichmann, I. Grkovic, S. Jankovic, L. Zgaga, A.L. Hartikainen, L. Peltonen, U. Gyllensten, A. Johansson, G. Zaboli, H. Campbell, S.H. Wild, J.F. Wilson, S. Glaser, G. Homuth, H. Volzke, M. Mangino, N. Soranzo, T.D. Spector, O. Polasek, I. Rudan, A.F. Wright, M. Heliovaara, C. Cooper, E. Dennison and J.W. Holloway
Type: Article | 2010 | Item not available on this server.

Protection against ultraviolet radiation involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo - Samantha Robinson, Sandra Dixon, Suzannah August, Brian Diffey, Kazumasa Wakamatsu, Shosuke Ito, Peter S. Friedmann and Eugene Healy
Type: Article | 2010 | Item not available on this server.

Type: Thesis | 2010

S

Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort study. - Martha Scott, Abid Raza, Wilfried Karmaus, Frances Mitchell, Jane Grundy, Ramesh J. Kurukulaaratchy, S. Hasan Arshad and Graham Roberts
Type: Article | 2010 | Item not available on this server.

Are exhaled nitric oxide measurements using the portable NIOX MINO repeatable? - Anna Selby, Bernie Claton, Jane Grundy, Katy Pike, Kirsty Drew, Abid Raza, Ramesh Kurukulaaratchy, S. Hasan Arshad and Graham Roberts
Type: Article | 2010 | Item not available on this server.

Frmd7 expression in developing mouse brain - J. Self, H.M. Haitchi, H. Griffiths, S.T. Holgate, D.E. Davies and A. Lotery
Type: Article | 2010 | Item not available on this server.

Type: Monograph | 2010 | The Stationery Office | Item not available on this server.

Type: Article | 2010

Ossifying fibromyxoid tumour of the sphenoid sinus - S.D. Shetty, R.J. Salib, S.B. Nair, N. Mathad and J. Theaker
Type: Article | 2010 | Item not available on this server.

Immunogenicity and reactogenicity of a 13-valent-pneumococcal conjugate vaccine administered at 2, 4, and 12 months of age: a double-blind randomized active-controlled trial - Matthew D. Snape, Chaam L. Klinger, Elvis D. Daniels, Tessa M. John, Helen Layton, Llinos Rollinson, Sarah Pestridge, Sandra Dymond, Eva Galiza, Susan Tansey, Daniel A. Scott, Sherryl A. Baker, Thomas R. Jones, Ly-Mee Yu, William C. Gruber, Emilio A. Emini, Saul N. Faust, Adam Finn, Paul T. Heath and Andrew J. Pollard
Type: Article | 2010 | Item not available on this server.

The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria. - Maria Staevska, Todor A. Popov, Tanya Kralimarkova, Cvetelina Lazarova, Steliana Kraeva, Dora Popova, Diana S. Church, Vasil Dimitrov and Martin K. Church
Type: Article | 2010 | Item not available on this server.

Monocyte-derived macrophages matured under prolonged hypoxia transcriptionally up-regulate HIF-1? mRNA - Karl J. Staples, Fattah Sotoodehnejadnematalahi, Helen Pearson, Marion Frankenberger, Lorenza Francescut, Loems Ziegler-Heitbrock and Bernard Burke
Type: Article | 2010 | Item not available on this server.

On-chip epithelial barrier function assays using electrical impedance spectroscopy - Tao Sun, Emily J. Swindle, Jane E. Collins, Judith A. Holloway, Donna E. Davies and Hywel Morgan
Type: Article | 2010 | Item not available on this server.

T

Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes - Cristina Teodosio, Andrés C. García-Montero, María Jara-Acevedo, Laura Sánchez-Muñoz, Ivan Álvarez-Twose, Rosa Núñez, Lawrence B. Schwartz, Andrew F. Walls, Luis Escribano and Alberto Orfao
Type: Article | 2010 | Item not available on this server.

Chlamydia trachomatis: small genome, big challenges. - Nicholas R. Thomson and Ian N. Clarke
Type: Article | 2010 | Item not available on this server.

Increase in serotype 6C pneumococcal carriage, United Kingdom - Anna S. Tocheva, Johanna M.C. Jefferies, Myron Christodoulides, Saul N. Faust and Stuart C. Clarke
Type: Letter | 2010 | Item availability restricted.

Surfactant phospholipids, surfactant proteins and inflammatory markers during acute lung injury in children - David A. Todd, Michael J. Marsh, Anne George, Neil G. Henderson, Heather Barr, Seby Sebastian, Graeme T. Clark, Grielof Koster, Howard W. Clark and Anthony D. Postle
Type: Article | 2010 | Item not available on this server.

U

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma - L Uller, M. Leino, Nicole Bedke, David Sammut, B. Green, L. Lau, P.H. Howarth, S.T. Holgate and D.E. Davies
Type: Article | 2010 | Item not available on this server.

The Swedish new variant of chlamydia trachomatis: genome sequence, morphology, cell tropism and phenotypic characterization - Magnus Unemo, Helena M.B. Seth-Smith, Lesley T. Cutcliffe, Rachel J. Skilton, David Barlow, David Goulding, Kenneth Persson, Simon Harris, Anne Kelly, Carina Bjartling, Hans Fredlund, Per Olcén, N icholas R. Thomson and Ian N. Clarke
Type: Article | 2010 | Item not available on this server.

V

Time trends in the prevalence of peanut allergy: three cohorts of children from the same geographical location in the UK. - C. Venter, S. Hasan Arshad, J. Grundy, B. Pereira, C. Bernie Clayton, K. Voigt, B. Bateman, B. Higgins and T. Dean
Type: Article | 2010 | Item not available on this server.

Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients - Pandurangan Vijayanand, Kesta Durkin, Guido Hartmann, Jaymin Morjaria, Gregory Seumois, Karl J. Staples, David Hall, Christina Bessant, Michelle Bartholomew, Peter H. Howarth, Peter S. Friedmann and Ratko Djukanovic
Type: Article | 2010 | Item not available on this server.

W

Open-label, randomised, parallel-group, multicentre study to evaluate the safety, tolerability and immunogenicity of an AS03(B)/oil-in-water emulsion-adjuvanted (AS03(B)) split-virion versus non-adjuvanted whole-virion H1N1 influenza vaccine in UK children 6 months to 12 years of age - C.S. Waddington, N. Andrews, K. Hoschler, W.T. Walker, C. Oeser, A. Reiner, T. John, Suzanne Wilkinson, M. Casey, P.E. Eccleston, R.J. Allen, I. Okike, S. Ladhani, E. Sheasby, P. Waight, A.C. Collinson, P.T, Heath, A. Finn, S.N. Faust, M.D. Snape, E. Miller and A.J. Pollard
Type: Article | 2010 | Item not available on this server.

Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study - Claire S. Waddington, W.T. Walker, C. Oeser, A. Reiner, T. John, S. Wilkins, M. Casey, P.E. Eccleston, R.J. Allen, I. Okike, S. Ladhani, E. Sheasby, K. Hoschler, N. Andrews, P. Waight, A.C. Collinson, P.T. Heath, A. Finn, S.N. Faust, M.D. Snape, E. Miller and A.J. Pollard
Type: Article | 2010 | Item not available on this server.

Type: Article | 2010 | Item not available on this server.

X

Expression of CD1d and presence of invariant NKT cells in classical Hodgkin lymphoma - Chuanhui Xu, Riemer de Vries, Lydia Visser, Arjan Diepstra, Stephan D. Gadola, Sibrand Poppema and Anke van den Berg
Type: Article | 2010 | Item not available on this server.

Z

Trends in eczema in the first 18 years of life: results from the Isle of Wight 1989 birth cohort study - A.H. Ziyab, A. Raza, W. Karmaus, N. Tongue, H. Zhang, S. Matthews, S.H. Arshad and G. Roberts
Type: Article | 2010 | Item not available on this server.

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