Items where Division is "Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences
Clinical and Experimental Sciences" and Year is 2021
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Number of items: 169.
Type: Dataset
| 2021
| University of Southampton
Type: Letter
| 2021
Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma - Adnan Azim, Ben Green, Laurie Lau, Hitasha Rupani, Nivenka Jayasekera, Kenneth Bruce and Peter Howarth
Type: Article
| 2021
Clinical evaluation of type 2 disease status in a real-world population of difficult to manage asthma using historic Electronic Health Care Records of Blood Eosinophil counts - Adnan Azim, Colin Newell, Clair Barber, Matthew Harvey, Deborah Knight, Anna Freeman, Wei Chern Gavin Fong, Paddy Dennison, Hans Michael Haitchi, Ratko Djukanovic, Ramesh Kurukulaaratchy and Peter Howarth
Type: Article
| 2021
Severe acute respiratory syndrome coronavirus 2 infection in those on mepolizumab therapy - Adnan Azim, Laura Pini, Zeeshan Khakwani, Santosh Kumar and Peter Howarth
Type: Article
| 2021
| Item not available on this server.
Effects of celecoxib augmentation of antidepressant or anxiolytic treatment on affective symptoms and inflammatory markers in patients with anxiety disorders: exploratory study - David Baldwin, Hesham Yousry Elhelaly Elnazer and Anthony Sampson
Type: Article
| 2021
Sputum processing by mechanical dissociation: a rapid alternative to traditional sputum assessment approaches - Clair Barber, Laurie Lau, Jonathan Ward, Thomas Daniels, Alastair Watson, Karl J. Staples, Thomas Wilkinson and Peter Howarth
Type: Article
| 2021
Integration of a hybrid photon counting detector into a lab-based μCT scanner for 3D X-ray histology - Philip J Basford, Orestis L. Katsamenis, Richard Boardman, Stephanie Robinson, Elena Konstantinopoulou, Spyridon Gkoumas, Thomas Thuering, Peter Lackie, Simon Cox and Philipp Schneider
Type: Conference or Workshop Item
| 2021
Effectiveness of the manual diaphragmatic stretching technique on respiratory function in cerebral palsy: a randomised controlled trial - Surussawadi Bennett, Wantana Siritaratiwat, Nittaya Tanrangka, Michael John Bennett and Jaturat Kanpittaya
Type: Article
| 2021
| Item not available on this server.
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK - Chloe I Bloom, Thomas M Drake, Annemarie B Docherty, Brian J Lipworth, Sebastian L Johnston, Jonathan S Nguyen-Van-Tam, Gail Carson, Jake Dunning, Ewen M Harrison, J Kenneth Baillie, Malcolm G Semple, Paul Cullinan and Peter J M Openshaw
Type: Article
| 2021
| Item not available on this server.
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection - Cornelia Blume, Claire Jackson, Cosma Spalluto, Jelmer Legebeke, Liliya Nazlamova, Franco Conforti, Jeanne-Marie Perotin-Collard, Martin Frank, John Butler, Max Crispin, Janice Coles, James Thompson, Robert Ridley, Lareb Dean, Matthew Loxham, Stephanie Reikine, Adnan Azim, Kamran Tariq, David Johnston, Paul James Stuart Skipp, Ratko Djukanovic, Diana Baralle, Christopher Mccormick, Donna Davies, Jane Lucas, Gabrielle Wheway and Vito Mennella
Type: Article
| 2021
Sarcopenia and myosteatosis predict adverse outcomes after emergency laparotomy: a multi-centre observational cohort study - Samantha Body, Marjolein A. P. Ligthart, Saqib Rahman, James Ward, Peter May-miller, Philip H. Pucher, Nathan J. Curtis, Malcolm A. West, Clizia Airofarulla, Louise Alder, Nicholas Baylem, David Berry, Anastasia Benjafield, Thakshyanee Bhuvanakrishna, Amanda Bond, Richard Booth, Jack Broadhurst, James P. Byrne, Rachel Carten, Duncan Chambler, Heather Davis, Mark R. Edwards, Paul Froggatt, Nader Francis, Michael P. W. Grocott, Gui Han Lee, Denny Z. H. Levett, Camilla Hickish, Frances Howse, Prashan Kangesu, Zeeshan Khawaja, Jieyun Lee, Chui Lee, Jenny Mclachlan, Stuart Mercer, Alex H. Mirnezami, Brendan Moran, Victoria Morrison Jones, Kate Nicholls, Steven W. M. Olde Damink, Katherine Pearson, John N. Primrose, Paul Robinson, Eva Sorensen, Benjamin M. Stubbs, Noori Suhail, Simon Toh, Michael Terry, Alexios Tzivanakis and Timothy J. Underwood
Type: Article
| 2021
The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study - Florencia A.T. Boshier, Cristina Venturini, Oliver Stirrup, Kordo Saeed and et al.
Type: Article
| 2021
| Item not available on this server.
Natural killer cells and regulatory T cells cross talk in hepatocellular carcinoma: exploring therapeutic options for the next decade - Amber G. Bozward, Frazer Warricker, Ye H. Oo and Salim I. Khakoo
Type: Review
| 2021
| Item not available on this server.
Injecting network structure determines the most efficient strategy to achieve Hepatitis C elimination in people who inject drugs - Chloe Brown, Martin Siegele, Mark Wright, Charlotte Cook, Julie Parkes, Salim I Khakoo, Rachel Sacks-Davis and Ryan M. Buchanan
Type: Article
| 2021
Schools closures during the COVID-19 pandemic: A catastrophic global situation - Danilo Buonsenso, Damian Roland, Cristina De Rose, Pablo Vásquez-Hoyos, Bazlin Ramly, Jessica Nandipa Chakakala-Chaziya, Alasdair Munro and Sebastián González-Dambrauskas
Type: Letter
| 2021
| Item not available on this server.
Unravelling the mechanisms driving multimorbidity in COPD to develop holistic approaches to patient-centred care - H. Burke and T. M.A. Wilkinson
Type: Article
| 2021
| Item not available on this server.
Priorities for child health research across the UK and Ireland - Katrina Cathie, Alastair G Sutcliffe, Srini Bandi, David Coghlan, Stephen W Turner and Colin Powell
Type: Article
| 2021
| Item availability restricted.
Type: Dataset
| 2021
| University of Southampton
Type: Dataset
| 2021
| University of Southampton
Feasibility and acceptability of transcranial stimulation in obsessive-compulsive symptoms (FEATSOCS): study protocol for a randomised controlled trial of transcranial direct current stimulation (tDCS) in obsessive-compulsive disorder (OCD) - Eduardo Cinosi, David Adam, Ibrahim Aslan, David Baldwin, Kieran Chillingsworth, Arun Enara, Tim Gale, Kabir Garg, Matthew Garner, Robert Gordon, Natalie Hall, Nathan T M Huneke, Sonay Kucukterzi-Ali, Joanne McCarthy, Daniel Meron, Deela Monji-Patel, Roisin Mooney, Trevor Robbins, Megan Smith, Nick Sireau, David Wellsted, Solange Wyatt and Naomi A Fineberg
Type: Article
| 2021
Pragmatic randomised controlled trial of molecular point-of-care testing for respiratory pathogens versus routine clinical care in critically ill adults with pneumonia: (SARIPOC) Trial protocol - Tristan W. Clark, Stephen Poole, Kordo Saeed, Ahilanandan Dushianthan and Mike Grocott
Type: Other
| 2021
The management of ADHD in children and adolescents: bringing evidence to the clinic: perspective from the European ADHD Guidelines Group (EAGG) - David Coghill, Tobias Banaschewski, Samuele Cortese, Philip Asherson, Daniel Brandeis, Jan Buitelaar, David Daley, Marina Danckaerts, Ralf W. Dittmann, Manfred Doepfner, Maite Ferrin, Chris Hollis, Martin Holtmann, Santosh Paramala, Edmund Sonuga-Barke, César Soutullo, Hans Christoph Steinhausen, Saskia Van der Oord, I. C.K. Wong, Alessandro Zuddas and Emily Simonoff
Type: Review
| 2021
Sonic hedgehog signaling promotes peri-lesion cell proliferation and functional improvement after cortical contusion injury - Benjamin Coles, Elshadaie Solomon, Brandon Desousa, Anan Shtaya, Ashley Pringle, Shyam Gajavelli, Nedal Dabab, Malik Zaben, Diederik Bulters, Ross Bullock and Aminul Ahmed
Type: Article
| 2021
Prevalence of bacteriuria among pregnant women and changes in antibiotic resistance patterns: a six-year study - Erin Cotton, Samir Umranikar, Kordo Saeed and Bhaskar Somani
Type: Conference or Workshop Item
| 2021
| Item not available on this server.
FeNO non-suppression identifies corticosteroid-resistant Type-2 signaling in severe asthma - Simon Couillard, Rahul Shrimanker, Rekha Chaudhuri, Adel H Mansur, Lorcan P. Mcgarvey, Liam G Heaney, Stephen J Fowler, Peter Bradding, Ian D Pavord and Timothy S.c. Hinks
Type: Article
| 2021
COVID-19 - a redox disease what a stress pandemic can teach us about resilience and what we may learn from the reactive species interactome about its treatment - Andrew F Cumpstey, Anna D Clark, Jerome Santolini, Alan A Jackson and Martin Feelisch
Type: Article
| 2021
Neisseria lactamica controlled human infection model - Adam P. Dale, Diane F. Gbesemete, Robert C. Read and Jay R. Laver
Type: Book Section
| 2021
| Humana Press Inc.
| Item availability restricted.
An IRF1-IRF4 toggle-switch controls tolerogenic and immunogenic transcriptional programming in human Langerhans cells - James Davies, Andres F. Vallejo, Sofia Sirvent, Gemma Porter, Kalum Clayton, Yamkela Qumbelo, Patrick Stumpf, Jonathan West, Clive Gray, Nyaradzo Chigorimbo-Murefu, Benjamin Macarthur and Marta Polak
Type: Article
| 2021
Should routine eye examinations be included in treatment bundles for patients with candidemia? - H Russell Day, John B Bond, Bhaskar Gupta, Kordo Saeed and Mark P Breazzano
Type: Letter
| 2021
| Item not available on this server.
Human intestinal macrophages are involved in the pathology of both ulcerative colitis and Crohn disease - Suranga Dharmasiri, Eva M. Garrido-Martin, Richard, James Harris, Adrian C. Bateman, Jane E. Collins, J.R. Fraser Cummings and Tilman Sanchez-Elsner
Type: Article
| 2021
Dupuytren's interventions surgery versus collagenase (DISC) trial: study protocol for a pragmatic, two-arm parallel-group, non-inferiority randomised controlled trial - Joseph Dias, Catherine Arundel, Puvan Tharmanathan, Ada Keding, Charlie Welch, Belen Corbacho, Maria Armaou, Paul Leighton, Christopher Bainbridge, Michael Craigen, Lydia Flett, Samantha Gascoyne, Catherine Hewitt, Elaine James, Sophie James, Nick Johnson, Judy Jones, Catherine Knowlson, Priya Radia, David Torgerson, David Warwick and Michelle Watson
Type: Article
| 2021
Establishing an invertebrate Galleria mellonella greater wax moth larval model of Neisseria gonorrhoeae infection - Aiste Dijokaite, Maria Victoria Humbert, Emma Borkowski, Roberto M. La Ragione and Myron Christodoulides
Type: Article
| 2021
Type: Article
| 2021
Predictive role of haematological determinants on outcomes of critically Ill COVID-19 patients admitted to intensive care unit - Ahilanandan Dushianthan, Nabil Abdul, Josh Dmochowski, Izabela James, Lesley Heesom, Jennifer Westwood, Judith Effney, Sarah Bruty, Kordo Saeed, Savita Rangarajan and Rashid Kazmi
Type: Article
| 2021
Methodology to detect oxidised phospholipids and their relevance in disease - Ahilanandan Dushianthan and Anthony Postle
Type: Review
| 2021
| Item availability restricted.
Concurrent validity of an Estimator of Weekly Alcohol Consumption (EWAC) based on the Extended AUDIT - Peter Dutey-Magni, Jamie Brown, John Holmes and Julia Sinclair
Type: Article
| 2021
| Item availability restricted.
Comment on "Evidence that the ProPerDP method is inadequate for protein persulfidation detection due to lack of specificity" - Éva Dóka, Elias S.J. Arnér, Edward E. Schmidt, Tobias P. Dick, Albert van der Vliet, Jing Yang, Réka Szatmári, Tamás Ditrói, John L. Wallace, Giuseppe Cirino, Kenneth Olson, Hozumi Motohashi, Jon M. Fukuto, Michael D. Pluth, Martin Feelisch, Takaaki Akaike, David A. Wink, Louis J. Ignarro and Péter Nagy
Type: Article
| 2021
Efficacy and safety of single-dose liposomal amphotericin B in patients with visceral leishmaniasis in Bangladesh: a real-life experience - Md Rezaul Ekram, Mohammad Robed Amin, Mohammad Jahid Hasan, Md Abdullah Saeed Khan, Rajib Nath, Pranab Kumar Mallik, Alex Lister and Monjur Rahman
Type: Article
| 2021
| Item not available on this server.
Type: Article
| 2021
| Item not available on this server.
Neonatal hypoxic-ischaemic encephalopathy: Motor impairment beyond cerebral palsy - Gergo Erdi-Krausz, Ruben Rocha, Alice Brown, Archana Myneni, Finn Lennartsson, Andrea Romsauerova, Rina Cianfaglione, Caroline J Edmonds and Brigitte Vollmer
Type: Article
| 2021
| Item availability restricted.
Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy - Simon Eschweiler, James Clarke, Ciro Ramírez-suástegui, Bharat Panwar, Ariel Madrigal, Serena J. Chee, Ioannis Karydis, Edwin Woo, Aiman Alzetani, Somaia Elsheikh, C. J. Hanley, G. J. Thomas, Peter S. Friedmann, Tilman Sanchez-elsner, Ferhat Ay, Christian H. Ottensmeier and Pandurangan Vijayanand
Type: Article
| 2021
Response to Verd and Verd Re: "COVID-19: A Redox Disease-What a Stress Pandemic Can Teach Us About Resilience and What We May Learn from the Reactive Species Interactome About Its Treatment" - Martin Feelisch, Andrew F Cumpstey, Anna D Clark, Jerome Santolini and Alan A Jackson
Type: Article
| 2021
| Item not available on this server.
Development and validation of the Food Allergy Severity Score - Montserrat Fernández-Rivas, Ismael Gómez García, Alejandro Gonzalo-Fernández, Manuel Fuentes Ferrer, Sabine Dölle-Bierke, Guadalupe Marco-Martín, Barbara K Ballmer-Weber, Riccardo Asero, Simona Belohlavkova, Kirsten Beyer, Frédéric de Blay, Michael Clausen, Mareen R Datema, Ruta Dubakiene, Kate E C Grimshaw, Karin Hoffmann-Sommergruber, Jonathan O'B Hourihane, Monika Jedrzejczak-Czechowicz, André C Knulst, Tanya Kralimarkova, Thuy-My Le, Nikolaos G Papadopoulos, Todor A Popov, Lars K Poulsen, Ashok Purohit, Suranjith L Seneviratne, Angela Simpson, Atanasios Sinaniotis, Mirjana Turkalji, Sonia Vázquez-Cortés, Rosialzira N Vera-Berrios, Antonella Muraro, Margitta Worm, Graham Roberts, Ronald van Ree, Cristina Fernández-Pérez, Paul J Turner and E N Clare Mills
Type: Article
| 2021
Selinexor enhances NK cell activation against malignant B cells via downregulation of HLA-E - Jack, Graham Fisher, Salim Khakoo, Mark Cragg, Francesco Forconi, Peter Johnson, Amber Doyle, christopher Walker, yosef landesman and Matthew Blunt
Type: Article
| 2021
Real-world omalizumab and mepolizumab treated difficult asthma phenotypes and their clinical outcomes - Wei Chern Gavin Fong, Adnan Azim, Deborah Knight, Heena Mistry, Anna Freeman, Mae Felongco, Aref Kyyaly, Matthew Harvey, Patrick Dennison, Hongmei Zhang, Peter Howarth, S Hasan Arshad, Ramesh J Kurukulaaratchy and Mohammed Aref Kyyaly
Type: Article
| 2021
Asthma did not increase in-hospital Covid-19 related mortality in a tertiary UK hospital - Wei Chern Gavin Fong, Florina Borca, Hang Phan, Helen E Moyses, Paddy Dennison, Ramesh J Kurukulaaratchy and Hans Michael Haitchi
Type: Article
| 2021
Childhood food allergy and food allergen sensitisation are associated with adult airways disease: a birth cohort study - Wei Chern Gavin Fong, Adrian Chan, Hongmei Zhang, John W Holloway, Graham Roberts, Ramesh Kurukulaaratchy and Syed Hasan Arshad
Type: Article
| 2021
| Item availability restricted.
Exercise training induces a shift in extracellular redox status with alterations in the pulmonary and systemic redox landscape in asthma - Anna Freeman, Doriana Cellura, Magdalena Minnion, Bernadette Fernandez, C. Mirella Spalluto, Denny Levett, Andrew Bates, Timothy Wallis, Alastair Watson, Sandra Jack, Karl J. Staples, Mike P. Grocott, Martin Feelisch and Tom M.A. Wilkinson
Type: Article
| 2021
Comparison of a theoretically driven cognitive therapy (the Feeling Safe Programme) with befriending for the treatment of persistent persecutory delusions: a parallel, single-blind, randomised controlled trial - Daniel Freeman, Richard Emsley and Rowan Diamond
Type: Article
| 2021
| Item not available on this server.
Lower airways clinical outcome measures for use in primary ciliary dyskinesia research, a scoping review - Florian Gahleitner, James Thompson, Claire Jackson, Jana, Franziska Hueppe, Laura Behan, Eleonora Dehlink, Myrofora Goutaki, Florian S. Halbeisen, Ana Paula Lima de Queiroz, Guillaume Thouvenin, Claudia E. Kuehni, Philipp Latzin, Jane Lucas and Bruna Rubbo
Type: Article
| 2021
| Item availability restricted.
Inductively coupled plasma mass spectrometry method for plasma and intracellular antimony quantification applied to pharmacokinetics of meglumine antimoniate - Diana J Garay-Baquero, David E Rebellón-Sánchez, Miguel D Prieto, Lina Giraldo-Parra, Adriana Navas, Sheryl Atkinson, Stuart McDougall and Maria Adelaida Gómez
Type: Article
| 2021
Current landscape of nutrition within prehabilitation oncology research: A scoping review - Chelsia Gillis, Sarah J. Davies, Francesco Carli, Paul E. Wischmeyer, Stephen A. Wootton, Alan A. Jackson, Bernhard Riedel, Luise V. Marino, Denny Z. H. Levett and Malcolm A. West
Type: Article
| 2021
COVID-19 encephalitis with SARS-CoV-2 detected in cerebrospinal fluid presenting as a stroke mimic - Diarmuid Glavin, Denise Kelly, Greta K Wood, Beth MS Mccausland, Mark A Ellul, Aravinthan Varatharaj, Ian Galea, Rhys H Thomas, Benedict D Michael and Brian Gallen
Type: Article
| 2021
Nitrite and myocardial ischaemia reperfusion injury. Where are we now? - Kayleigh Griffiths, Jordan J. Lee, Michael P. Frenneaux, Martin Feelisch and Melanie Madhani
Type: Review
| 2021
| Item not available on this server.
SafeFit Trial: virtual clinics to deliver a multimodal intervention to improve psychological and physical well-being in people with cancer. Protocol of a COVID-19 targeted non-randomised phase III trial - Chloe Grimmett, Andrew Bates, Malcolm West, Samantha Leggett, Judit Varkonyi-Sepp, Anna Campbell, June Davis, Stephen Wootton, Clare Shaw, Rachael Barlow, Joanna Ashcroft, Andrew Scott, Helen Moyes, Lesley Hawkins, Denny Z H Levett, Fran Williams, Michael P W Grocott and Sandy Jack
Type: Article
| 2021
Type: Dataset
| 2021
| University of Southampton
Development and validation of the ISARIC 4C deterioration model for adults hospitalised with COVID-19: a prospective cohort study - Rishi K Gupta, Ewen M Harrison, Antonia Ho, Annemarie B Docherty, Stephen R Knight, Maarten van Smeden, Ibrahim Abubakar, Marc Lipman, Matteo Quartagno, Riinu Pius, Iain Buchan, Gail Carson, Thomas M Drake, Jake Dunning, Cameron J Fairfield, Carrol Gamble, Christopher A Green, Sophie Halpin, Hayley E Hardwick, Karl A Holden, Peter W Horby, Clare Jackson, Kenneth A Mclean, Laura Merson, Jonathan S Nguyen-Van-Tam, Lisa Norman, Piero L Olliaro, Mark G Pritchard, Clark D Russell, James Scott-Brown, Catherine A Shaw, Aziz Sheikh, Tom Solomon, Cathie Sudlow, Olivia V Swann, Lance Turtle, Peter J M Openshaw, J Kenneth Baillie, Malcolm G Semple and Mahdad Noursadeghi
Type: Article
| 2021
| Item not available on this server.
EAACI guideline: preventing the development of food allergy in infants and young children (2020 update) - Susanne Halken, Antonella Muraro, Debra de Silva, Ekaterina Khaleva, Elizabeth Angier, Stefania Arasi, Hasan Arshad, Henry T Bahnson, Kirsten Beyer, Robert Boyle, George du Toit, Motohiro Ebisawa, Philippe Eigenmann, Kate Grimshaw, Arne Hoest, Carla Jones, Gideon Lack, Kari Nadeau, Liam O'Mahony, Hania Szajewska, Carina Venter, Valérie Verhasselt, Gary WK Wong and Graham Roberts
Type: Article
| 2021
Dual dean entrainment with volume ratio modulation for efficient droplet co-encapsulation: extreme single-cell indexing - Jack Harrington, Luis Blay Esteban, Jonathan Butement, Andres F Vallejo, Simon I R Lane, Bhavwanti Sheth, Maaike S A Jongen, Rachel Parker, Patrick S Stumpf, Rosanna C G Smith, Ben D MacArthur, Matthew J J Rose-Zerilli, Marta E Polak, Tim Underwood and Jonathan West
Type: Article
| 2021
| Item availability restricted.
Tools for shared annotation of correlative 2D light microscopy and 3D X-ray histology - Elaine, Ming Li Ho, Janina Wolf, Matthew Lawson, T. E. Trandafir, Elena Konstantinopoulou, Orestis L. Katsamenis, Andrew Stubbs, Peter Lackie, Jan von der Thüsen and Philipp Schneider
Type: Conference or Workshop Item
| 2021
| Item availability restricted.
Incidental findings in UK healthy volunteers screened for a COVID-19 vaccine trial - Susanne H Hodgson, Poppy Iveson, Jessica Larwood, Sophie Roche, Hazel Morrison, Catherine Cosgrove, Eva Galiza, Sabina Ikram, Nana-Marie Lemm, Savviz Mehdipour, Daniel Owens, Mihaela Pacurar, Michael Schumacher, Robert H Shaw, Saul N Faust, Paul T Heath, Andrew J Pollard, Katherine R W Emary, Katarina M Pollock and Rajeka Lazarus
Type: Article
| 2021
A case-control study of the locus coeruleus degeneration in Alzheimer’s disease - Ruihua Hou, Rebecca Beardmore, Clive Holmes, Clive Osmond and Angela Darekar
Type: Article
| 2021
Type: Article
| 2021
| Item not available on this server.
Examining lysyl oxidase-like modulation of collagen architecture in 3D spheroid models of idiopathic pulmonary fibrosis via second-harmonic generation microscopy - Darian S. James, Christopher J. Brereton, Donna E. Davies, Mark G. Jones and Paul J. Campagnola
Type: Article
| 2021
| Item not available on this server.
Research priorities in pediatric parenteral nutrition: a consensus and perspective from ESPGHAN/ESPEN/ESPR/CSPEN - Mark J Johnson, Alexandre Lapillonne, Jiri Bronsky, Magnus Domellof, Nicholas Embleton and Silvia Iacobelli
Type: Review
| 2021
Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architecture - Peter Johnson, Artemios Karvounis, H. Johnson Singh, Christopher J Brereton, Konstantinos Bourdakos, Kelly Lunn, James J.W. Roberts, Donna Davies, Otto Muskens, Mark Jones and Sumeet Mahajan
Type: Article
| 2021
“You have to change your whole life”: A qualitative study of the dynamics of treatment adherence among adults with tuberculosis in the United Kingdom - Aaron S. Karat, Annie S.K. Jones, Ibrahim Abubakar, Colin N.J. Campbell, Amy L. Clarke, Caroline S. Clarke, Marcia Darvell, Adam T. Hill, Robert Horne, Heinke Kunst, Mike Mandelbaum, Ben G. Marshall, Ceri McSparron, Ananna Rahman, Helen R. Stagg, Jacqui White, Marc C.I. Lipman and Karina Kielmann
Type: Article
| 2021
SARS-CoV-2 evolution during treatment of chronic infection - Steven A Kemp, Dami A Collier, Rawlings P Datir, Isabella A T M Ferreira, Salma Gayed and Aminu Jahun
Type: Article
| 2021
| Item not available on this server.
A peptide: MHC based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors. - Salim Khakoo, Pauline E Rettman, Matthew Blunt, Rebecca Fulton, Andres Vallejo Pulido, Leidy Bastidas Legarda, Laura Espana-Serrano, Marta Polak, Aymen Al-Shamkhani and Christelle Retiere
Type: Article
| 2021
Perceptions of adolescents and young adults with allergy and/or asthma and their parents on EAACI guideline recommendations about transitional care: A European survey - Ekaterina Khaleva, Rebecca Knibb, Audrey DunnGalvin, Marta Vazquez-Ortiz, Pasquale Comberiati, Cherry Alviani, Teresa Garriga-Baraut, Mary Hazel Gowland, Claudia Gore, Elizabeth Angier, Katharina Blumchen, Bettina Duca, Valérie Hox, Britt Jensen, Charlotte G Mortz, Helena Pite, Oliver Pfaar, Alexandra F Santos, Silvia Sanchez-Garcia, Frans Timmermans and Graham Roberts
Type: Article
| 2021
| Item availability restricted.
Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta‐analysis - Jong Yeob Kim, Min Je Choi, Sungji Ha, Jimin Hwang, Ai Koyanagi, Elena Dragioti, Joaquim Radua, Lee Smith, Louis Jacob, Gonzalo Salazar Pablo, Seung Won Lee, Dong Keon Yon, Trevor Thompson, Samuele Cortese, Gianluca Lollo, Chih‐sung Liang, Che‐sheng Chu, Paolo Fusar‐poli, Keun‐ah Cheon, Jae Il Shin and Marco Solmi
Type: Article
| 2021
| Item availability restricted.
Toy story: a cross-sectional survey of toy populations in tertiary neonatal units - Adam J King, Matthew Jones, Mark J Johnson and Olie Chowdhury
Type: Article
| 2021
| Item not available on this server.
Author Correction: Morphological and cytokine profiles as key parameters to distinguish between Gram-negative and Gram-positive bacterial keratitis - Aris Konstantopoulos, Maria Del Mar Cendra, Michael Tsatsos, Mariam Elabiary, Myron Christodoulides and Parwez Hossain
Type: Article
| 2021
| Item not available on this server.
A Role for Mucolytics and Expectorants in Aiding Inhaled Therapies in Asthma? [Response To Letter] - Ramesh J Kurukulaaratchy, Wei Chern Gavin Fong and Aref Kyyaly
Type: Article
| 2021
New Real-World Insights Into Severe Asthma: All About the Eosinophil? - Ramesh J Kurukulaaratchy and Heena Mistry
Type: Editorial
| 2021
| Item not available on this server.
Circulating miRNAs – a potential tool to identify severe asthma risk? - Mohammed Aref Kyyaly, Tilman Sanchez-Elsner, Peijun He, Collin L. Sones, S Hasan Arshad and Ramesh J. Kurukulaaratchy
Type: Letter
| 2021
CD8+CD103+ tissue-resident memory T cells convey reduced protective immunity in cutaneous squamous cell carcinoma - Chester Lai, George Stewart Coltart, Andrew Shapanis, Conor Healy, Ahmad Alabdulkareem, Sara Selvendran, Jeffrey Theaker, Matthew Sommerlad, Matthew Rose-Zerilli, Aymen Al-Shamkhani and Eugene Healy
Type: Article
| 2021
ENTPD1(CD39) expression inhibits ultraviolet radiation-induced DNA damage repair via purinergic signaling and is associated with metastasis in human cutaneous squamous cell carcinoma - Chester Lai and Eugene Healy
Type: Article
| 2021
A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage - Jay Laver, Diane Gbesemete, Adam Dale, Zoe Caroline Pounce, Carl N Webb, Eleanor F Roche, Jonathan Guy, Graham A Berreen, Konstantinos Belogiannis, Alison Hill, Muktar Ibrahim, Muhammad Ahmed, David Cleary, Anish Pandey, Holly E. Humphries, Lauren Allen, Hans De Graaf, Martin C. J. Maiden, Saul Faust, Andrew Gorringe and Robert Read
Type: Article
| 2021
Immunofluorescence-guided segmentation of three-dimensional features in micro-computed tomography datasets of human lung tissue - Matthew Lawson, Orestis L. Katsamenis, David Chatelet, Aiman Alzetani, Oliver Larkin, Ian Haig, Philipp Schneider, Peter Lackie and Jane Warner
Type: Article
| 2021
| Item not available on this server.
Red blood cell and endothelial eNOS independently regulate circulating nitric oxide metabolites and blood pressure - Francesca Leo, Tatsiana Suvorava, Sophia K Heuser, Junjie Li, Anthea LoBue, Frederik Barbarino, Eugenia Piragine, Rebekka Schneckmann, Beate Hutzler, Miranda E Good, Bernadette O. Fernandez, Lukas Vornholz, Stephen Rogers, Allan Doctor, Maria Grandoch, Johannes Stegbauer, Eddie Weitzberg, Martin Feelisch, Jon O Lundberg, Brant E Isakson, Malte Kelm and Miriam M Cortese-Krott
Type: Article
| 2021
Type: Article
| 2021
Serotype distribution of invasive, non-invasive and carried Streptococcus pneumoniae in Malaysia: a meta-analysis - Alex J J Lister, Cheng Foh Le, Eddy Seong Guan Cheah, Mohd Nasir Mohd Desa, David W Cleary and Stuart C Clarke
Type: Article
| 2021
Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial - Xinxue Liu, Robert H. Shaw, Arabella S.V. Stuart, Melanie Greenland, Parvinder K. Aley, Nick J. Andrews, Jonathan S. Nguyen-Van-Tam and Matthew D. Snape
Type: Article
| 2021
| Item not available on this server.
The effects of neoadjuvant chemoradiotherapy and an in-hospital exercise training programme on physical fitness and quality of life in locally advanced rectal cancer patients: a randomised controlled trial (The EMPOWER Trial) - Lisa Loughney, Malcolm A West, Helen Moyses, Andrew Bates, Graham J Kemp and Lesley Hawkins
Type: Article
| 2021
Type: Article
| 2021
Oligomeric Aβ1-42 induces an AMD-like phenotype and accumulates in lysosomes to impair RPE function - Savannah A. Lynn, David A. Johnston, Jenny A. Scott, Rosie Munday, Roshni S. Desai, Eloise Keeling, Ruaridh Weaterton, Alexander Simpson, Dillon Davis, Thomas Freeman, David S. Chatelet, Anton Page, Angela J. Cree, Helena Lee, Tracey A. Newman, Andrew J. Lotery and J. Arjuna Ratnayaka
Type: Article
| 2021
Preterm birth during the COVID‐19 pandemic: parental experience - LV Marino, N Collaço, MJ Johnson and AS Darlington
Type: Article
| 2021
| Item availability restricted.
A feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients - Daniel S. Martin, Margaret McNeil, Chris Brew-Graves, Helder Filipe, Ronan O’Driscoll, Jia Liu Stevens, Rachel Burnish, Andrew F. Cumpstey, Norman R. Williams, Michael G. Mythen and Michael P.W. Grocott
Type: Article
| 2021
| Item not available on this server.
Does lung function change in the months after an asthma exacerbation in children? - Joanne Martin, Marielle W. Pijnenburg, Graham Roberts, Katherine C. Pike, Helen Petsky, Anne B. Chang, Stanley J. Szefler, Peter Gergen, Francoise Vermeulen, Robin Vael and Steve Turner
Type: Article
| 2021
Screening, assessment and management of perioperative malnutrition: a survey of UK practice - Lewis Matthews, Stephen Wootton, S.J. Davies and Denny Levett
Type: Article
| 2021
AsthmaMap: an interactive knowledge repository for mechanisms of asthma - Alexander Mazein, Olga Ivanova, Irina Balaur, Marek Ostaszewski, Valeriya Berzhitskaya, Tatiana Serebriyskaya, Thomas Ligon, Jan Hasenauer, Bertrand De Meulder, Rupert W Overall, Ludovic Roy, Richard G Knowles, Craig E Wheelock, Sven-Erik Dahlen, Kian Fan Chung, Ian M Adcock, Graham Roberts, Ratko Djukanovic, Johann Pellet, Piotr Gawron, Rudi Balling, Anke H Maitland-van der Zee, Reinhard Schneider, Peter J Sterk and Charles Auffray
Type: Article
| 2021
Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness - Helen T McKenna, Katie A O'Brien, Bernadette O Fernandez, Magdalena Minnion, Adam Tod, Ben D McNally, James A West, Julian L Griffin, Michael P Grocott, Michael G Mythen, Martin Feelisch, Andrew J Murray and Daniel S Martin
Type: Article
| 2021
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7 - Kordo Saeed
Type: Article
| 2021
| Item not available on this server.
Metabolic dysfunction induced by a high-fat diet modulates hematopoietic stem and myeloid progenitor cells in brown adipose tissue of mice - Kyle T. Mincham, Kunjal Panchal, Prue H. Hart, Robyn M. Lucas, Martin Feelisch, Richard B Weller, Vance B. Matthews, Deborah H. Strickland and Shelley Gorman
Type: Article
| 2021
| Item not available on this server.
The clinical implications of Aspergillus Fumigatus sensitization in difficult-to-treat asthma patients - Heena Mistry, Hilda Maria Ajsivinac Soberanis, Mohammad Aref Kyyaly, Adnan Azim, Clair Barber, Deborah Knight, Colin Newell, Hans Michael Haitchi, Tom Wilkinson, Peter Howarth, Grégory Seumois, Pandurangan Vijayanand, S Hasan Arshad and Ramesh J Kurukulaaratchy
Type: Article
| 2021
| Item availability restricted.
Powered respirators are effective, sustainable, and cost-effective personal protective equipment for SARS-CoV-2 - Alasdair Munro, Jacqui Prieto, Emmanouil Mentzakis, Mohammed AM Mansour, Nitin Mahobia, Peter Baker, Sarah Herbert, Trevor Smith, Matthew Hine, Joann Hall, Angie McClarren, Mike Davidson, Julie Brooks, Jane Fisher, David Griffiths, Hywel Morgan, Corrado Giulietti, Saul Faust and Paul Elkington
Type: Article
| 2021
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial - Alasdair P S Munro, Leila Janani, Victoria Cornelius, Parvinder K Aley, Gavin Babbage, David Baxter, et al., Jonathan Nguyen-Van-Tam, Matthew D. Snape, Xinxue Liu and Saul N Faust
Type: Article
| 2021
EAACI guideline: Anaphylaxis (2021 update) - Antonella Muraro, Margitta Worm, Cherry Alviani, Victoria Cardona, Audrey DunnGalvin, Lene Heise Garvey, Carmen Riggioni, Debra de Silva, Elizabeth Angier, Stefania Arasi, Abdelouahab Bellou, Kirsten Beyer, Diola Bijlhout, Maria Beatrice Bilo, Carsten Bindslev-Jensen, Knut Brockow, Montserrat Fernandez-Rivas, Susanne Halken, Britt Jensen, Ekaterina Khaleva, Louise J. Michaelis, Hanneke N. G. Oude Elberink, Lynne Regent, Angel Sanchez, Berber J. Vlieg-Boerstra and Graham Roberts
Type: Article
| 2021
| Item availability restricted.
Cardiac protection by oral sodium thiosulfate in a rat model of L-NNA-induced heart disease - Isabel T.N. Nguyen, Lucas M. Wiggenhauser, Marian Bulthuis, Jan-Luuk Hillebrands, Martin Feelisch, Marianne C. Verhaar, Harry van Goor and Jaap A. Joles
Type: Article
| 2021
Amyloid-β and α-synuclein immunotherapy: from experimental studies to clinical trials - Jacqui, Taryn Nimmo, Louise Kelly, Ajay Verma, Roxana-Octavia Carare, James Nicoll and Jean-Cosme Dodart
Type: Review
| 2021
Immunotherapy with UB-312 in the Thy1-SNCA mouse improves motor performance and reduces oligomeric α-synuclein in the brain and gut - Jacqui, Taryn Nimmo, Harry Smith, Jessica Teeling, James Nicoll, Ajay Verma, Jean-Cosme Dodart, Chang Yi Wang and Roxana-Octavia Carare
Type: Article
| 2021
An inducible transposon mutagenesis approach for the intracellular human pathogen Chlamydia trachomatis - Colette E O'Neill, Rachel J. Skilton, Jade Forster, David W. Cleary, Sarah A. Pearson, David J. Lampe, Nicholas R. Thomson and Ian N. Clarke
Type: Article
| 2021
Vitamin D levels and intensive care unit outcomes of a cohort of critically ill COVID-19 patients - Laurence Orchard, Matthew Baldry, Myra Nasim-Mohi, Chantelle Monck, Kordo Saeed, Michael P.W. Grocott and Ahilanandan Dushianthan
Type: Article
| 2021
| Item not available on this server.
Analysis of Excess Mortality Data at Different Altitudes During the COVID-19 Outbreak in Ecuador - Esteban Ortiz-Prado, Raul Patricio Fernandez Naranjo, Eduardo Vasconez, Katherine Simbaña-Rivera, Trigomar Correa-Sancho, Alex Lister, Manuel Calvopiña and Ginés Viscor
Type: Article
| 2021
| Item not available on this server.
Influence of hypoxia on the epithelial-pathogen interactions in the lung: implications for respiratory disease - Lee K. Page, Karl J. Staples, C. Mirella Spalluto, Alastair Watson and Thomas Wilkinson
Type: Article
| 2021
Urgent need to develop evidence-based COVID-19 recommendations for primary schools - Sanjay Patel, Cristina Epalza Ibarrondo, Julie Toubiana and Dimitri Van Der Linden
Type: Letter
| 2021
| Item not available on this server.
Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX, a double-blind, placebo-controlled, randomised cross-over study - Matthew J Pavitt, Adam Lewis, Sara C Buttery, Bernadette O Fernandez, Monika Mikus-Lelinska, Winston A S Banya, Martin Feelisch, Michael I Polkey and Nicholas S Hopkinson
Type: Article
| 2021
| Item availability restricted.
Epigenetics in the Uterine Environment: How Maternal Diet and ART May Influence the Epigenome in the Offspring with Long-Term Health Consequences - Irene Peral Sanchez, Batoul Hojeij, Diego Ojeda Pedraza, Regine P.M. Steegers-Theunissen and Sandrine Willaime-Morawek
Type: Review
| 2021
Adrenaline to improve survival in out-of-hospital cardiac arrest: the PARAMEDIC2 RCT - Gavin D. Perkins, Chen Ji, Felix Achana, John J.M. Black, Karl Charlton, James Crawford, Adam de Paeztron, Charles Deakin, Mark Docherty, Judith Finn, Rachael T. Fothergill, Simon Gates, Imogen Gunson, Kyee Han, Susie Hennings, Jessica Horton, Kamran Khan, Sarah Lamb, John Long, Joshua Miller, Fionna Moore, Jerry Nolan, Lyndsey O’shea, Stavros Petrou, Helen Pocock, Tom Quinn, Nigel Rees, Scott Regan, Andy Rosser, Charlotte Scomparin, Anne Slowther and Ranjit Lall
Type: Article
| 2021
An evaluation of the mental health impact of SARS-CoV-2 on patients, general public and healthcare professionals: A systematic review and meta-analysis - Peter Phiri, Rema Ramakrishnan, Shanaya Rathod, Kathryn Elliot, Tony Thayanandan, Natasha Sandle, Nyla Haque, Steven W.h. Chau, Oscar W.h. Wong, Sandra S.m. Chan, Evelyn K.y. Wong, Vanessa Raymont, Sheena K. Au-yeung, David Kingdon and Gayathri Delanerolle
Type: Article
| 2021
| Item not available on this server.
Molecular investigation of the unfolded protein response in select human tauopathies - Aleksandra P Pitera, Iain J Hartnell, Lucy Scullard, Kirsten L Williamson, Delphine Boche, Vincent O'Connor and Katrin Deinhardt
Type: Article
| 2021
| Item not available on this server.
How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC) - Stephen Poole, Jennifer Townsend, Heiman Wertheim, Stephen P. Kidd, Tobias Welte, Philipp Schuetz, Charles Edouard Luyt, Albertus Beishuizen, Jens Ulrik Stæhr Jensen, Juan González del Castillo, Mario Plebani and Kordo Saeed
Type: Article
| 2021
Antibiotic-loaded polymersomes for clearance of intracellular burkholderia thailandensis - Eleanor Porges, Dominic Jenner, Adam W Taylor, James S P Harrison, Antonio De Grazia, Alethia R Hailes, Kimberley M Wright, Adam O Whelan, Isobel H Norville, Joann L Prior, Sumeet Mahajan, Caroline A Rowland, Tracey A Newman and Nicholas D Evans
Type: Article
| 2021
| Item availability restricted.
Rapid phospholipid turnover after surfactant nebulization in severe COVID- 19 infection: a randomized clinical trial - Anthony Postle, Howard Clark, Jim Fink, Jens Madsen, Grielof Koster, Madhuriben Panchal, Ratko Djukanovic, David Brealey, Michael Grocott and Ahilanandan Dushianthan
Type: Article
| 2021
| Item availability restricted.
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative - John R. Prowle, Lui G. Forni, Max Bell, Michelle S. Chew, Mark Edwards, Morgan E. Grams, Michael P.W. Grocott, Kathleen D. Liu, David McIlroy, Patrick T. Murray, Marlies Ostermann, Alexander Zarbock, Sean M. Bagshaw, Raquel Bartz, Samira Bell, Azra Bihorac, Tong J. Gan, Charles E. Hobson, Michael Joannidis, Jay L. Koyner, Denny Z.H. Levett, Ravindra L. Mehta, Timothy E. Miller, Michael G. Mythen, Mitra K. Nadim, Rupert M. Pearse, Thomas Rimmele, Claudio Ronco, Andrew D. Shaw and John A. Kellum
Type: Review
| 2021
Type: Dataset
| 2021
| University of Southampton
The role of extracellular vesicles as a shared disease mechanism contributing to multimorbidity in patients with COPD - Laura V. Reid, C. Mirella Spalluto, Alastair Watson, Karl J. Staples and Tom M.A. Wilkinson
Type: Article
| 2021
Plasma nitrate levels are related to metabolic syndrome and are not altered by treatment with DPP-4 inhibitor linagliptin: a randomised, placebo-controlled trial in patients with early type 2 diabetes mellitus - Melanie Reijrink, Stefanie A De Boer, Anniek M Van Roon, Riemer H J A Slart, Bernadette O Fernandez, Martin Feelisch, Hiddo J L Heerspink, Harry Van Goor, Jan-Luuk Hillebrands and Douwe J Mulder
Type: Article
| 2021
Predicted number of peanut-allergic patients needed to treat with epicutaneous immunotherapy (EPIT) to prevent one allergic reaction: A novel approach to assessing relevance - Benjamin C. Remington, Stef J. Koppelman, Todd D. Green, Gideon Lack, Graham Roberts and Dianne E. Campbell
Type: Letter
| 2021
| Item not available on this server.
Type: Dataset
| 2021
| University of Southampton
Type: Dataset
| 2021
| University of Southampton
| Item availability restricted.
Spectrum, risk factors, and outcomes of neurological and psychiatric complications of COVID-19: a UK-wide cross-sectional surveillance study - Amy L Ross Russell, Marc Hardwick, Athavan Jeyanantham, Laura M White, Saumitro Deb, Girvan Burnside, Harriet Joy, Craig J Smith, Thomas A Pollak, Timothy R Nicholson, Nicholas WS Davies, Hadi Manji, Ava Easton, Stephen Ray, Michael S Zandi, Jonathan P. Coles, David K. Menon, Aravinthan Varatharaj, Beth Mccausland, Mark A Ellul, Naomi Thomas, Gerome Breen, Stephen Keddie, Michael P Lunn, John PS Burn, Graziella Quattrocchi, Luke Dixon, Claire M Rice, George Pengas, Rustam Al-Shahi Salman, Alan Carson, Eileen M. Joyce, Martin R Turner, Laura A Benjamin, Tom Solomon, Rachel Kneen, Sarah Pett, Rhys H Thomas, Benedict D Michael and Ian Galea
Type: Article
| 2021
Recent insights into the management of inflammation in asthma - Hitasha Rupani, Wei Chern Gavin Fong, Aref Kyyaly and Ramesh J Kurukulaaratchy
Type: Review
| 2021
Type: Article
| 2021
Type: Article
| 2021
Type: Article
| 2021
| Item not available on this server.
Bacterial toxins in musculoskeletal infections - Kordo Saeed, Parham Sendi, William V. Arnold, Thomas W. Bauer, Débora C. Coraça‐Huber, Antonia F. Chen, Hyonmin Choe, John L. Daiss, Michelle Ghert, Noreen J. Hickok, Kohei Nishitani, Bryan D. Springer, Paul Stoodley, Thomas P. Sculco, Barry D. Brause, Javad Parvizi, Alex C. McLaren and Edward M. Schwarz
Type: Article
| 2021
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study - Katherine A. Twohig, Tommy Nyberg, Asad Zaidi, Simon Thelwall, Mary A. Sinnathamby, Shirin Aliabadi, Shaun R. Seaman, Ross J. Harris, Russell Hope, Jamie Lopez-Bernal, Eileen Gallagher, Andre Charlett, Daniela De Angelis, Anne M. Presanis and Gavin Dabrera
Type: Article
| 2021
| Item not available on this server.
Food allergy across the globe - Vanitha Sampath, Elissa M. Abrams, Bahman Adlou, Cezmi Akdis, Mübeccel Akdis, Helen A. Brough, Susan Chan, Pantipa Chatchatee, R. Sharon Chinthrajah, Renata Rodrigues Cocco, Antoine Deschildre, Philippe Eigenmann, Cesar Galvan, Ruchi Gupta, Elham Hossny, Jennifer J. Koplin, Gideon Lack, Michael Levin, Lynette P. Shek, Mika Makela, David Mendoza-Hernandez, Antonella Muraro, Nikolaos G. Papadopoulous, Ruby Pawankar, Kirsten P. Perrett, Graham Roberts, Cansin Sackesen, Hugh Sampson, Mimi L.K. Tang, Alkis Togias, Carina Venter, Christopher Michael Warren, Lisa M. Wheatley, Gary W.K. Wong, Kirsten Beyer, Kari C. Nadeau and Harald Renz
Type: Review
| 2021
| Item availability restricted.
Multiphasic prehabilitation across the cancer continuum: a narrative review and conceptual framework - Daniel Santa Mina, Stefanus J. Van Rooijen, Enrico M. Minnella, Shabbir M. H. Alibhai, Priya Brahmbhatt, Susanne O. Dalton, Chelsia Gillis, Michael P. W. Grocott, Doris Howell, Ian M. Randall, Catherine M. Sabiston, Julie K. Silver, Gerrit Slooter, Malcolm West, Sandy Jack and Franco Carli
Type: Article
| 2021
The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix-significance for protein elimination failure arteriopathies - Matthew MacGregor Sharp, Jordan Cassidy, Thomas Thornton, James Lyles, Abby Keable, Maureen Gatherer, Masato Yasui, Yoichiro Abe, Shinsuke Shibata, Roy O Weller, Dariusz C Górecki and Roxana O Carare
Type: Article
| 2021
Topological data analysis reveals genotype-phenotype relationships in primary ciliary dyskinesia - Amelia Shoemark, Bruna Rubbo, Marie Legendre, Mahmoud R. Fassad, Eric G. Haarman, Sunayna Best, Irma CM Bon, Joost Brandsma, Pierre-Regis Burgel, Gunnar Carlsson, Siobhan Carr, Mary Carroll, Matt Edwards, Estelle Escudier, Isabelle Honore, David Hunt, Gregory Jouvion, Michael R. Loebinger, Bernard Maitre, Deborah Morris-Rosendahl, Jean-Francois Papon, Camille Parsons, Mitali.P Patel, N.S. Thomas, Guillaume Thouvenin, Woolf T. Walker, Robert Wilson, Claire Hogg, Hannah Mitchison and Jane Lucas
Type: Article
| 2021
What medical students think about measurement of their wellbeing and the implications for pastoral support: cross sectional survey and qualitative interviews - G. Simons, R. Effah and D.S. Baldwin
Type: Other
| 2021
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure - David A. Smith, Carlota Fernandez-Antunez and Andrea Magri
Type: Article
| 2021
Adult advanced life support European Resuscitation Council Guidelines 2021: Leitlinien des European Resuscitation Council 2021 - Jasmeet Soar, Bernd W. Böttiger, Pierre Carli, Keith Couper, Charles D. Deakin, Therese Djärv, Carsten Lott, Theresa Olasveengen, Peter Paal, Tommaso Pellis, Gavin D. Perkins, Claudio Sandroni and Jerry P. Nolan
Type: Review
| 2021
| Item not available on this server.
MR-proADM as prognostic factor of outcome in COVID-19 patients - Emanuela Sozio, Carlo Tascini, Martina Fabris, Federica D’Aurizio, Chiara De Carlo, Elena Graziano, Flavio Bassi, Francesco Sbrana, Andrea Ripoli, Alberto Pagotto, Alessandro Giacinta, Valentina Gerussi, Daniela Visentini, Paola De Stefanis, Maria Merelli, Kordo Saeed and Francesco Curcio
Type: Article
| 2021
| Item not available on this server.
Bibliography of published COVID-19 in children literature - Philippa Anna Stilwell, Alasdair P.S. Munro, Emre Basatemur, Nishanthi Talawila Da Camara, Rachel Harwood and Damian Roland
Type: Review
| 2021
| Item not available on this server.
SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study - Oliver Stirrup, Florencia Boshier, Cristina Venturini, José Afonso Guerra-Assunção and Adela Alcolea-Medina
Type: Article
| 2021
| Item not available on this server.
SARS-CoV-2 Viral load at presentation to hospital is independently associated with the risk of death - Alex Tanner, Hang Thi Thu Phan, Nathan Brendish, Florina Borca, Kate Beard, Stephen Poole and Tristan Clark
Type: Article
| 2021
| Item availability restricted.
Analysis of immune landscape in pancreatic and ileal neuroendocrine tumours demonstrates an immune cold tumour microenvironment - Lulu Tanno, Salma Naheed, Jonathan Dunbar, Jo Tod, Maria A Lopez, Julian Taylor, Maria Machado, Bryan Green, Margaret Ashton-Key, Serena J Chee, Oliver Wood, Neil W Pearce, Gareth J Thomas, Peter S Friedmann, Judith Cave and Christian H Ottensmeier
Type: Article
| 2021
| Item not available on this server.
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 - Ryan S Thwaites, Ashley Sanchez Sevilla Uruchurtu, Matthew K Siggins, Felicity Liew, Clark D Russell, Shona C Moore, Cameron Fairfield, Edwin Carter, Simon Abrams, Charlotte-Eve Short, Thilipan Thaventhiran, Emma Bergstrom, Zoe Gardener, Stephanie Ascough, Christopher Chiu, Annemarie B Docherty, David Hunt, Yanick J Crow, Tom Solomon, Graham P Taylor, Lance Turtle, Ewen M Harrison, Jake Dunning, Malcolm G Semple, J Kenneth Baillie and Peter JM Openshaw
Type: Article
| 2021
| Item not available on this server.
Recombinant ADAMTS13 reduces abnormally up-regulated von Willebrand factor in plasma from patients with severe COVID-19 - Peter L Turecek, Rachel C Peck, Savita Rangarajan, Christopher Reilly-Stitt, Michael A Laffan, Rashid Kazmi, Izabela James, Ahilanandan Dushianthan, Gerald Schrenk, Herbert Gritsch, Bruce M Ewenstein, Bjorn Mellgard, Wolfhard Erdlenbruch, Nisha Jain, Nikolaus B Binder and Andrew D Mumford
Type: Article
| 2021
Normal values for respiratory sleep polygraphy in children aged 4 to 9 years at 2,560 m above sea level - Santiago Ucros, Claudia Granados, Catherine Hill, Jose Antonio Castro-Rodriguez and Juan Camilo Ospina
Type: Article
| 2021
Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering - Andres F. Vallejo, James Davies, Amit Grover, Ching-hsuan Tsai, Robert Jepras, Marta E. Polak and Jonathan West
Type: Article
| 2021
Transitioning from intravenous to subcutaneous vedolizumab in patients with inflammatory bowel disease (TRAVELESS) - Esther Ventress, David Young, Sohail Rahmany, Clare Harris, Marion Bettey, Trevor Smith, Helen Moyses, Magdalena Lech, Markus Gwiggner, Richard Felwick and J R Fraser Cummings
Type: Article
| 2021
| Item availability restricted.
Immunogenicity and safety of a 3-antigen hepatitis B vaccine vs a single-antigen hepatitis B vaccine: A phase 3 randomized clinical trial - Timo Vesikari, Adam Finn, Pierre Van Damme, Isabel Leroux-Roels, Geert Leroux-Roels, Nathan Segall, Azhar Toma, Gerald Vallieres, Ronnie Aronson, Dennis Reich, Samir Arora, Peter J. Ruane, Clancy L. Cone, Michael Manns, Catherine Cosgrove, Saul N. Faust, Maheshi N. Ramasamy, Nathalie Machluf, Johanna N. Spaans, Bebi Yassin-Rajkumar, David Anderson, Vlad Popovic and Francisco Diaz-Mitoma
Type: Article
| 2021
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England - Erik Volz, Swapnil Mishra, Meera Chand, Jeffrey C Barrett, Robert Johnson and Lily Geidelberg
Type: Article
| 2021
| Item not available on this server.
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine : a pooled analysis of four randomised trials - Merryn Voysey, Sue Ann Costa Clemens, Shabir A Madhi, Lily Y Weckx, Pedro M Folegatti, Parvinder K Aley, Brian Angus, Vicky L Baillie, Shaun L Barnabas, Qasim E Bhorat, Sagida Bibi, Carmen Briner, Paola Cicconi, Elizabeth A Clutterbuck, Andrea M Collins, Clare L Cutland, Thomas C Darton, Keertan Dheda, Christina Dold, Christopher J A Duncan, Katherine R W Emary, Katie J Ewer, Amy Flaxman, Lee Fairlie, Saul N Faust, Shuo Feng, Daniela M Ferreira, Adam Finn, Eva Galiza, Anna L Goodman, Catherine M Green, Christopher A Green, Melanie Greenland, Catherine Hill, Helen C Hill, Ian Hirsch, Alane Izu, Daniel Jenkin, Carina C D Joe, Simon Kerridge, Anthonet Koen, Gaurav Kwatra, Rajeka Lazarus, Vincenzo Libri, Patrick J Lillie, Natalie G Marchevsky, Andrew Smith, David P J Turner, Thomas White and Christopher J Williams
Type: Article
| 2021
| Item not available on this server.
Type: Dataset
| 2021
| University of Southampton
Dysregulation of COVID-19 related gene expression in the COPD lung - Alastair Watson, Lisa Oberg, Bastian Angermann, C. Mirella Spalluto, Michael Huhn, Hannah Burke, Doriana Cellura, Anna Freeman, Daniel Muthas, Damla Etal, Graham Belfield, Fredrik Karlsson, Karl Nordstrom, Kristoffer Ostridge, Karl J. Staples and Thomas Wilkinson
Type: Article
| 2021
Evidence around the impact of pulmonary rehabilitation and exercise on redox status in COPD: a systematic review - Alastair Watson, Tom M A Wilkinson and Anna Freeman
Type: Review
| 2021
A systematic review of the definitions and prevalence of feeding intolerance in preterm infants - Charlotte L Weeks, Luise V Marino and Mark J Johnson
Type: Article
| 2021
| Item not available on this server.
The role of non-typeable Haemophilus influenzae biofilms in Chronic Obstructive Pulmonary Disease - Jake R Weeks, Karl J. Staples, C. Mirella Spalluto, Alastair Watson and Tom M. Wilkinson
Type: Review
| 2021
The Wessex Fit-4-Cancer Surgery Trial (WesFit): a protocol for a factorial-design, pragmatic randomised-controlled trial investigating the effects of a multi-modal prehabilitation programme in patients undergoing elective major intra–cavity cancer surgery - Malcolm West, Andrew Bates, Chloe Grimmett, Cait Allen, Richard Green, Lesley Hawkins, Helen Moyses, Samantha Leggett, Denny Z H Levett, Sally Rickard, Judit Varkonyi-sepp, Fran Williams, Stephen Wootton, Matthew Hayes, Micheal P W Grocott and Sandy Jack
Type: Article
| 2021
The effects of cancer therapies on physical fitness before oesophagogastric cancer surgery: a prospective, blinded, multi-centre, observational, cohort study [version 1; peer review: 2 approved] - Malcolm A West, Zachos Anastasiou, Gareth Ambler, Lisa Loughney, Michael G Mythen, Thomas Owen, Gerard Danjoux, Denny Z H Levett, Jamie J Kelly, Sandy Jack and Michael P W Grocott
Type: Article
| 2021
Cardiopulmonary exercise testing has greater prognostic value than sarcopenia in oesophago-gastric cancer patients undergoing neoadjuvant therapy and surgical resection - Malcolm A. West, William Ca Baker, Saqib Rahman, Alicia Munro, Sandra Jack, Michael Pw Grocott, Timothy J. Underwood, Denny Zh Levett and Stephen Wootton
Type: Article
| 2021
| Item availability restricted.
Prehabilitation before surgery: is it for all patients? - Malcolm A. West, Sandy Jack and Michael P.w. Grocott
Type: Review
| 2021
Whole genome sequencing in the diagnosis of primary ciliary dyskinesia - Gabrielle Wheway, N. Simon Thomas, Mary Carroll, Janice Coles, Regan Doherty, Patricia, Mary Goggin, Ben Green, Amanda Harris, David Hunt, Claire Jackson, Jenny Lord, Vito Mennella, James Thompson, Woolf Walker and Jane Lucas
Type: Article
| 2021
| Item availability restricted.
A prenylated dsRNA sensor protects against severe COVID-19 - Arthur Wickenhagen, Elena Sugrue, Spyros Lytras, Srikeerthana Kuchi, Marko Noerenberg, Matthew L Turnbull and et al.
Type: Article
| 2021
The state of mental health care in China - Ziyan Xu, Maximilian Gahr, Yutao Xiang, David Kingdon, Nicolas Rüsch and Gang Wang
Type: Review
| 2021
| Item not available on this server.
Leukotrienes are dispensable for vaginal neutrophil recruitment as part of the immunopathological response during experimental vulvovaginal candidiasis - Junko Yano, David J White, Anthony P Sampson, Floyd L Wormley and Paul L Fidel
Type: Article
| 2021
Bidirectional epithelial-mesenchymal crosstalk provides self-sustaining pro-fibrotic signals in pulmonary fibrosis - Liudi Yao, Yilu Zhou, Juanjuan Li, Leanne Wickens, Franco Conforti, Anna Rattu, Fathima M Ibrahim, Aiman Alzetani, Benjamin Marshall, Sophie V. Fletcher, David Hancock, Timothy Wallis, Julian Downward, Robert Ewing, Luca Richeldi, Paul Skipp, Donna Davies, Mark Jones and Yihua Wang
Type: Article
| 2021
A multimodal quality improvement approach to promote normothermia in very preterm infants - Aneurin Young, Fameesh Azeez, Santan Pawalu Godad, Preethish Shetty and Alok Sharma
Type: Article
| 2021
| Item availability restricted.
Total body water in full term and preterm newborns: systematic review and meta-analysis - Aneurin Young, Lisa K Brown, Sarah Ennis, Mark Johnson and R.M. Beattie
Type: Article
| 2021
Poor CD4+ T Cell Immunogenicity Limits Humoral Immunity to P. falciparum Transmission-Blocking Candidate Pfs25 in Humans - Marija Zaric, Arianna Marini, Carolyn M Nielsen, Gaurav Gupta, David Mekhaiel, Thao P Pham, Sean C Elias, Iona J Taylor, Hans de Graaf, Ruth O Payne, Yuanyuan Li, Sarah E Silk, Chris Williams, Adrian V S Hill, Carole A Long, Kazutoyo Miura and Sumi Biswas
Type: Article
| 2021
Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial - Hans de Graaf, Ruth O. Payne, Iona Taylor, Kazutoyo Miura, Carol A. Long, Sean C. Elias, Marija Zaric, Angela M. Minassian, Sarah E. Silk, Lee Li, Ian D. Poulton, Megan Baker, Simon J. Draper, Diane Gbesemete, Nathan J. Brendish, Filipa Martins, Arianna Marini, David Mekhaiel, Nick J. Edwards, Rachel Roberts, Johan Vekemans, Sarah Moyle, Saul N. Faust, Eleanor Berrie, Alison M. Lawrie, Fergal Hill, Adrian V.S. Hill and Sumi Biswas
Type: Article
| 2021
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells - Thushan I de Silva, Guihai Liu, Benjamin B Lindsey, Shona C Moore, Nienyun Sharon Hsu, Dhruv Shah, Dannielle Wellington, Alexander J Mentzer, Adrienn Angyal, Matthew D Parker, Zixi Ying, Xuan Yao, Lance Turtle and Susanna Dunachie
Type: Article
| 2021