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Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences
Cancer Sciences" and Year is 2022

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Number of items: 169.

A

Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10 - Mohamed Ahmed, Jared Mackenzie, Liku Bekele Tezera, Robert Krause, Barry Truebody, Diana Garay Baquero, Andres Vallejo Pulido, Katya Govender, John Adamson, Hayden Fisher, Jonathan W. Essex, Salah Mansour, Paul Elkington, Adrie J. C. Steyn and Alasdair Leslie
Type: Article | 2022

IL-33 induces an antiviral signature in mast cells but enhances their permissiveness for human rhinovirus infection - Charlene Akua Dufie Akoto, Anna Willis, Chiara Francesca Banas, Joseph A. Bell, Dean Bryant, Cornelia Blume, Donna E. Davies and Emily J. Swindle
Type: Article | 2022

Risk of developing a second primary cancer in male breast cancer survivors: a systematic review and meta-analysis - Isaac Allen, Hend Hassan, Eleni Sofianopoulou, Diana Eccles, Clare Turnbull, Marc Tischkowitz, Paul Pharoah and Antonis C Antoniou
Type: Article | 2022

Type: Thesis | 2022 | University of Southampton

Type: Thesis | 2022 | University of Southampton

BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells - Rachael Louise Arthur, Alexander Wathen, Elizabeth Lemm, Freda Stevenson, Francesco Forconi, Adam J Linley, Andrew Steele, Graham Packham and Beatriz Valle-argos
Type: Article | 2022

Deleterious genetic variation across the NOD-signaling pathway is associated with reduced NFKB-signaling transcription and upregulation of alternative inflammatory transcripts in paediatric inflammatory bowel disease - James Ashton, Konstantinos Boukas, Imogen, Sian Stafford, Guo Cheng, Rachel Haggarty, Tracy Coelho, Akshay Batra, Nadeem A. Afzal, Anthony Williams, Marta Polak, R. Mark Beattie and Sarah Ennis
Type: Article | 2022

B

Type: Article | 2022 | Item not available on this server.

Changes in the management of patients having radical radiotherapy for lung cancer during the first wave of the COVID-19 pandemic in the UK - K. Banfill, W. Croxford, I. Fornacon-Wood, K. Wicks, S. Ahmad, A. Britten, C. Carson, N. Dorey, M Hatton, C. Hiley, K. Thippu Jayaprakash, A. Jegannathen, P. Koh, N. Panakis, C. Peedell, A. Pope, C. Powell, C. Stilwell, B. Thomas, E. Toy, V. Wood, S. Yahya, S.Y. Zhou, G. Price and C. Faivre-Finn
Type: Article | 2022

Efficacy outcomes and prognostic factors from real-world patients with advanced non-small-cell lung cancer treated with first-line chemoimmunotherapy: the Spinnaker retrospective study - Giuseppe L Banna, Ornella Cantale, Sethupathi Muthuramalingam, Judith Cave, Charles Comins, Alessio Cortellini, Alfredo Addeo, Alessio Signori, Hayley McKenzie, Carles Escriu, Gloria Barone, Samuel Chan, Alexander Hicks, Hannah Bainbridge, David J Pinato, Christian Ottensmeier and Fabio Gomes
Type: Article | 2022

Type: Article | 2022

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles - Rahul Bhome, Muhammad Emaduddin, Massimiliano Mellone, Stephen Thirdborough, John Primrose, Gareth Thomas, Alexander Mirnezami and Abdulkadir Emre Sayan
Type: Article | 2022

Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma - Charles N. Birts, Constantinos Savva, Stéphanie A. Laversin, Alicia Lefas, Jamie Krishnan, Aron Schapira, Margaret Ashton-Key, Max Crispin, Peter W.M. Johnson, Jeremy P. Blaydes, Ellen Copson, Ramsey I. Cutress and Stephen A. Beers
Type: Article | 2022

Type: Dataset | 2022 | figshare | Item not available on this server.

KIR2DS2 expression identifies NK cells with enhanced anticancer activity - Matthew Blunt, Mark Cragg, Amber Doyle, Jack, Graham Fisher, Salim Khakoo, Francesco Forconi, Peter Johnson, Marta Ewa Polak, Lara, Victoria Graham, Andres Vallejo Pulido, Rebecca Fulton and Matthew Carter
Type: Article | 2022

Sarcopenia and myosteatosis predict adverse outcomes after emergency laparotomy: a multi-centre observational cohort study - Samantha Body, Marjolein A. P. Ligthart, Saqib Rahman, James Ward, Peter May-miller, Philip H. Pucher, Nathan J. Curtis, Malcolm A. West, Clizia Airofarulla, Louise Alder, Nicholas Baylem, David Berry, Anastasia Benjafield, Thakshyanee Bhuvanakrishna, Amanda Bond, Richard Booth, Jack Broadhurst, James P. Byrne, Rachel Carten, Duncan Chambler, Heather Davis, Mark R. Edwards, Paul Froggatt, Nader Francis, Michael P. W. Grocott, Gui Han Lee, Denny Z. H. Levett, Camilla Hickish, Frances Howse, Prashan Kangesu, Zeeshan Khawaja, Jieyun Lee, Chui Lee, Jenny Mclachlan, Stuart Mercer, Alex H. Mirnezami, Brendan Moran, Victoria Morrison Jones, Kate Nicholls, Steven W. M. Olde Damink, Katherine Pearson, John N. Primrose, Paul Robinson, Eva Sorensen, Benjamin M. Stubbs, Noori Suhail, Simon Toh, Michael Terry, Alexios Tzivanakis and Timothy J. Underwood
Type: Article | 2022

Tapasin mediated editing of the MHC I immunopeptidome is epitope specific and dependent on peptide off-rate, abundance and level of tapasin expression - Denise Boulanger, Leon R Douglas, Patrick Duriez, Yoyel Kang, Neil Dalchau, Edward James and Tim Elliott
Type: Article | 2022

Type: Book Section | 2022 | Springer | Item availability restricted.

Type: Dataset | 2022 | figshare | Item not available on this server.

Long-term outcomes and exploratory analyses of the randomized phase III BILCAP study - John Bridgewater, Peter Fletcher, Daniel H. Palmer, Hassan Z. Malik, Raj Prasad, Darius Mirza, Alan Anthony, Pippa G. Corrie, Stephen Falk, Meg Finch-Jones, Harpreet Wasan, Paul J. Ross, Lucy Wall, Jonathan Wadsley, Thomas R Jeffry Evans, Deborah D. Stocken, Clive Stubbs, Raaj Praseedom, Yuk Ting Ma, Brian Davidson, John P. Neoptolemos, Timothy Iveson, David Cunningham, O James Garden, Juan W. Valle and John Primrose
Type: Article | 2022

De-risking clinical trial failure through mechanistic simulation - Liam V. Brown, Jonathan Wagg, Rachel Darley, Andy van Hateren, Tim Elliott, Eammon Gaffney and Mark Coles
Type: Article | 2022

Type: Article | 2022

Nasogastric tube drainage and pyloric intervention after oesophageal resection: UK practice variation and effect on outcomes - Alexander Bull, Philip H Pucher, Nick Maynard, Timothy Underwood, Jesper Lagergren and James A Gossage
Type: Article | 2022

Margin status and survival outcomes after breast cancer conservation surgery: prospectively registered systematic review and meta-analysis - James R. Bundred, Sarah Michael, Beth Stuart, Ramsey I. Cutress, Kerri Beckmann, Bernd Holleczek, Jane E. Dahlstrom, Jacqui Gath, David Dodwell and Nigel J. Bundred
Type: Review | 2022

Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results - N Bundred, N Porta, A Murray Brunt, A Cramer, A Hanby, A M Shaaban, E A Rakha, A Armstrong, Ramsey Cutress, D Dodwell, M A Emson, A Evans, S M Hartup, K Horgan, S E Miller, S A McIntosh, J P Morden, J Naik, S Narayanan, J Ooi, A I Skene, D A Cameron and J M Bliss
Type: Article | 2022

Type: Article | 2022 | Item not available on this server.

C

Neuroblastoma: a master of disguise and a challenge to cure - Debora Calderoni, Giuseppe Barone, Martin Elliot, Deborah A. Tweedle, Ramya Ramanujachar and Juliet Gray
Type: Review | 2022

Impact of obesity, lifestyle factors and health interventions on breast cancer survivors - Nicola J Campbell, Charlotte Barton, Ramsey I Cutress and Ellen R Copson
Type: Review | 2022

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance - Ankur Chakravarthy, Ian Reddin, Stephen Henderson, Cindy Dong, Nerissa Kirkwood, Maxmilan Jeyakumar, Daniela Rothschild Rodriguez, Natalia Gonzalez Martinez, Jacqueline McDermott, Xiaoping Su, Nagayasau Egawa, Christina S. Fjeldbo, Vilde Eide Skingen, Heidi Lyng, Mari Kyllesø Halle, Camilla Krakstad, Afschin Soleiman, Susanne Sprung, Matt Lechner, Peter J.I. Ellis, Mark Wass, Martin Michaelis, Heidi Fiegl, Helga Salvesen, Gareth J Thomas, John Doorbar, Kerry Chester, Andrew Feber and Tim R. Fenton
Type: Article | 2022

Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment - Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A.C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J.W. van der Windt, Aron P. Kater, Graham Packham and Eric Eldering
Type: Article | 2022 | Item not available on this server.

High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in patients with CLL - Giorgia Chiodin, Francesco Forconi, Isla Henderson, Luis Del Rio Fernandez, Ian Tracy, Helen Parker, Jonathan Strefford, Jade Forster, Nora Potter, Benjamin Sale, Stuart Lanham, Freda Stevenson, Enrica Antonia Martino, Laura Ondrisova, Annalisa D'Avola, Silvia Bonfiglio, Lydia Scarfo, Lesley-Ann Sutton, Oliver Brake, Marek Mraz, Paolo Ghia and Samantha J. Drennan
Type: Article | 2022 | Item availability restricted.

Type: Article | 2022

Prognostic effect of body mass index in patients with advanced NSCLC treated with chemoimmunotherapy combinations - Alessio Cortellini, Biagio Ricciuti, Victor R. Vaz, Davide Soldato, Joao V. Alessi, Filippo G. Dall'olio, Giuseppe L. Banna, Sethupathi Muthuramalingam, Samuel Chan, Margarita Majem, Aida Piedra, Giuseppe Lamberti, Elisa Andrini, Alfredo Addeo, Alex Friedlaender, Francesco Facchinetti, Teresa Gorriá, Laura Mezquita, Delphine Hoton, Lacroix Valerie, Frank Aboubakar Nana, James Artingstall, Charles Comins, Massimo Di Maio, Andrea Caglio, Judith Cave, Hayley McKenzie, Thomas Newsom-Davis, Joanne S. Evans, Marcello Tiseo, Antonio D'Alessio, Claudia A.M. Fulgenzi, Benjamin Besse, Mark M. Awad and David J. Pinato
Type: Article | 2022

Type: Article | 2022

Type: Article | 2022 | Item availability restricted.

Type: Thesis | 2022 | University of Southampton

D

EORTC Quality of Life Group Item Library user guidelines - Anne-Sophie Darlington, Claire Piccinin, Dagmara Kuliś, Andrew Bottomley, Kristin Bjordal, Corneel Coens, Colin Johnson, Mogens Groenvold and Galina Velikova
Type: Book | 2022 | European Organisation for Research and Treatment of Cancer | Item availability restricted.

ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial - Andrew Davies, Sharon Barrans, Cathy Burton, Katy Mercer, Joshua Caddy, Fay Chinnery, Laura Day, Diana Fernando, Kirit Ardeshna, Graham Collins, John Radford, Simon Rule, Andrew Mcmillan, Peter Johnson and Gareth Griffiths
Type: Article | 2022

From theory to practice: an international approach to establishing prehabilitation programmes - June F. Davis, Stefan J. Van Rooijen, Chloe Grimmett, Malcom A. West, Anna M. Campbell, Rashami Awasthi, Gerrit D. Slooter, Michael P. Grocott, Franco Carli and Sandy Jack
Type: Article | 2022

Genomic profiling for clinical decision making in lymphoid neoplasms - Laurence De Leval, Ash A. Alizadeh, P. Leif Bergsagel, Elias Campo, Andrew Davies, Ahmet Dogan, Jude Fitzgibbon, Steven M. Horwitz, Ari M. Melnick, William G. Morice, Ryan D. Morin, Bertrand Nadel, Stefano A. Pileri, Richard Rosenquist, Davide Rossi, Itziar Salaverria, Christian Steidl, Steven P. Treon, Andrew D. Zelenetz, Ranjana H. Advani, Carl E. Allen, Stephen M. Ansell, Wing C. Chan, James R. Cook, Lucy B. Cook, Francesco D’amore, Stefan Dirnhofer, Martin Dreyling, Kieron Dunleavy, Andrew L. Feldman, Falko Fend, Philippe Gaulard, Paolo Ghia, John G. Gribben, Olivier Hermine, Daniel J. Hodson, Eric D. Hsi, Giorgio Inghirami, Elaine S. Jaffe, Kennosuke Karube, Keisuke Kataoka, Wolfram Klapper, Won Seog Kim, Rebecca L. King, Young H. Ko, Ann S. Lacasce, Georg Lenz, José I. Martin-subero, Miguel A. Piris, Stefania Pittaluga, Laura Pasqualucci, Leticia Quintanilla-martinez, Scott J. Rodig, Andreas Rosenwald, Gilles A. Salles, Jesus San-miguel, Kerry J. Savage, Laurie H. Sehn, Gianpietro Semenzato, Louis M. Staudt, Steven H. Swerdlow, Constantine S. Tam, Judith Trotman, Julie M. Vose, Oliver Weigert, Wyndham H. Wilson, Jane N. Winter, Catherine J. Wu, Pier L. Zinzani, Emanuele Zucca, Adam Bagg and David W. Scott
Type: Article | 2022 | Item availability restricted.

Copy number variants are ovarian cancer risk alleles at known and novel risk loci - Amber A. Devries, Joe Dennis, Jonathan P. Tyrer, Pei Chen Peng, Simon G. Coetzee, Alberto L. Reyes, Jasmine T. Plummer, Brian D. Davis, Stephanie S. Chen, Felipe Segato Dezem, Katja K.H. Aben, Hoda Anton-Culver, Natalia N. Antonenkova, Matthias W. Beckmann, Alicia Beeghly-Fadiel, Andrew Berchuck, Natalia V. Bogdanova, Nadja Bogdanova-Markov, James D. Brenton, Ralf Butzow, Ian Campbell, Jenny Chang-Claude, Georgia Chenevix-Trench, Linda S. Cook, Anna Defazio, Jennifer A. Doherty, Thilo Dork, Diana M. Eccles, A. Heather Eliassen, Peter A. Fasching, Renee T. Fortner, Graham G. Giles, Ellen L. Goode, Marc T. Goodman, Jacek Gronwald, Niclas Hakansson, Michelle A.T. Hildebrandt, Chad Huff, David G. Huntsman, Allan Jensen, Siddhartha Kar, Beth Y. Karlan, Elza K. Khusnutdinova, Lambertus A. Kiemeney, Susanne K. Kjaer, Jolanta Kupryjanczyk, Marilyne Labrie, Diether Lambrechts, Nhu D. Le, Jan Lubinski, Taymaa May, Usha Menon, Roger L. Milne, Francesmary Modugno, Alvaro N. Monteiro, Kirsten B. Moysich, Kunle Odunsi, Hakan Olsson, Celeste L. Pearce, Tanja Pejovic, Susan J. Ramus, Elio Riboli, Marjorie J. Riggan, Isabelle Romieu, Dale P. Sandler, Joellen M. Schildkraut, V. Wendy Setiawan, Weiva Sieh, Honglin Song, Rebecca Sutphen, Kathryn L. Terry, Pamela J. Thompson, Linda Titus, Shelley S. Tworoger, Els Van Nieuwenhuysen, Digna Velez Edwards, Penelope M. Webb, Nicolas Wentzensen, Alice S. Whittemore, Alicja Wolk, Anna H. Wu, Argyrios Ziogas, Matthew L. Freedman, Kate Lawrenson, Paul D.P. Pharoah, Douglas F. Easton, Simon A. Gayther and Michelle R. Jones
Type: Article | 2022

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study - Suzanne C. Dixon-Suen, Sarah J Lewis, Richard M. Martin, Dallas English, Terry Boyle, Graham Giles, Roger Milne and Brigid Lynch
Type: Article | 2022

P58 anonymous electronic IBD patient service feedback - Louise Downey, Sohail Rahmany, Matthew Stammers, Will Knibbs, Laura White, Richard Felwick and Markus Gwiggner
Type: Meeting abstract | 2022 | Item not available on this server.

Total pelvic exenteration with "high and wide" sacrectomy for recurrent rectal cancer: A video vignette - I Drami, J A Fletcher, A Corr, M A West, W Aston, G Hellawell, E M Burns and J T Jenkins
Type: Letter | 2022 | Item availability restricted.

Body composition and chemotherapy toxicity in women with early breast cancer (CANDO-3): protocol for an observational cohort study - Kesta Durkin, Mohammad, Adam Heetun, Sean Ewings, Richard Munday, Stephen Wootton, Lesley Turner, Ellen Copson and Ramsey Cutress
Type: Article | 2022

Type: Thesis | 2022 | University of Southampton

Type: Article | 2022

E

Paradoxes of cancer: survival at the brink - Jekaterina Erenpreisaa, Kristine Salminaa, Olga Anatskaya and Mark Cragg
Type: Article | 2022

Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs. - Simon Eschweiler, Ciro Ramírez-suástegui, Yingcong Li, Emma King, Lindsey Chudley, Thomas Jaya, Oliver Wood, Adrian von Witzleben, Danielle Jeffrey, Katy Mccann, Rabindra P. Singh, Gareth Thomas, Pandurangan Vijayanand and Christian H. Ottensmeier
Type: Article | 2022 | Item not available on this server.

High likelihood of actionable pathogenic variant detection in breast cancer genes in women with very early onset breast cancer - D. Gareth Evans, Elke M. van Veen, Helen J. Byers, Sarah J. Evans, George J. Burghel, Emma R. Woodward, Elaine F. Harkness, Diana Eccles, Stephanie L. Greville-Haygate, Jamie M. Ellingford, Naomi L. Bowers, Marta Pereira, Andrew J. Wallace, Sasha J. Howell, Anthony Howell, Fiona Lalloo, William G. Newman and Miriam Jane Smith
Type: Article | 2022

F

Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING): development and evaluation of an educational programme for healthcare professionals about BRCA1 & BRCA2 testing - Lesley Fallowfield, Ivonne Solis-Trapala, Rachel Starkings, Shirley May, Lucy Matthews, Diana Eccles, D. Gareth Evans, Clare Turnbull, Gillian Crawford and Valerie Jenkins
Type: Article | 2022

Type: Article | 2022 | Item not available on this server.

Disruption of the NKG2A:HLA-E immune checkpoint axis to enhance NK cell activation against Cancer - Jack G. Fisher, Amber D. P. Doyle, Lara V. Graham, Salim I. Khakoo and Matthew D. Blunt
Type: Article | 2022

Type: Article | 2022

Open sidewall excision for recurrent rectal cancer with gluteal flap reconstruction - a video vignette - Jordan Fletcher, Ioanna Drami, Elaine Burns, Maleeha Mughal, Malcolm A West, Alison Corr and John T Jenkins
Type: Letter | 2022

Inferior gluteal artery perforator flap reconstruction of the perineum: A Video Vignette - Jordan A Fletcher, Ioanna Drami, Malcolm A West, Elaine M Burns, David Ross, John Northover and John T Jenkins
Type: Letter | 2022

The impact of endoscopic ultrasound on the management and outcome of patients with oesophageal cancer: an update of a systematic review - K. G. Foley, J. Franklin, C. M. Jones, B. Coles, S. A. Roberts, T. J. Underwood and T. Crosby
Type: Article | 2022

Type: Article | 2022

G

Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD - A Garrett, C Loveday, L King, S Butler, R Robinson, C Horton, et al., Diana Eccles and Clare Turnbull
Type: Article | 2022

PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients - Daniele Giardiello, Maartje J Hooning, Michael Hauptmann, Renske Keeman, B A M Heemskerk-Gerritsen, Heiko Becher, Carl Blomqvist, Stig E Bojesen, Manjeet K Bolla, Nicola J Camp, Kamila Czene, Peter Devilee, Diana M Eccles, Peter A Fasching, Jonine D Figueroa, Henrik Flyger, Montserrat García-Closas, Christopher A Haiman, Ute Hamann, John L Hopper, Anna Jakubowska, Floor E Leeuwen, Annika Lindblom, Jan Lubiński, Sara Margolin, Maria Elena Martinez, Heli Nevanlinna, Ines Nevelsteen, Saskia Pelders, Paul D P Pharoah, Sabine Siesling, Melissa C Southey, Annemieke H van der Hout, Liselotte P van Hest, Jenny Chang-Claude, Per Hall, Douglas F Easton, Ewout W Steyerberg and Marjanka K Schmidt
Type: Article | 2022

Type: Dataset | 2022 | University of Southampton

Type: Article | 2022

Long-circulation zwitterionic dendrimer nanodrugs for phototherapy of tumors - Xiaolei Guo, Shukai Li, Jingrui Tian, Shengfu Chen, Guanglong Ma, Haiyan Xiao, Zhiwei Liu, Longgang Wang and Xiaohua Jiang
Type: Article | 2022 | Item availability restricted.

Type: Article | 2022

An international expert Delphi consensus on defining textbook Outcome in Liver Surgery (TOLS) - Burak Görgec, Andrea Benedetti Cacciaguerra, Timothy M Pawlik, Luca A Aldrighetti, Adnan A Alseidi, Umberto Cillo, Norihiro Kokudo, David A Geller, Go Wakabayashi, Horacio J Asbun, Marc G Besselink, Daniel Cherqui, Tan To Cheung, Pierre-Alain Clavien, Claudius Conrad, Mathieu D'Hondt, Ibrahim Dagher, Christos Dervenis, John Devar, Elijah Dixon, Bjørn Edwin, Mikhail Efanov, Giuseppe M Ettore, Alessandro Ferrero, Constantino Fondevilla, David Fuks, Felice Giuliante, Ho-Seong Han, Goro Honda, Oscar Imventarza, David A Kooby, Peter Lodge, Santiago Lopez-Ben, Marcel A Machado, Hugo P Marques, Nick O'Rourke, Juan Pekolj, Antonio D Pinna, Nazario Portolani, John Primrose, Fernando Rotellar, Andrea Ruzzenente, Erik Schadde, Ajith K Siriwardena, Sameer Smadi, Olivier Soubrane, Kenneth K Tanabe, Catherine S C Teh, Guido Torzilli, Thomas M Van Gulik, Marco Vivarelli, Stephen J Wigmore and Mohammad Abu Hilal
Type: Article | 2022

H

Type: Article | 2022

Type: Dataset | 2022 | Zenodo | Item not available on this server.

UK recommendations for SDHA germline genetic testing and surveillance in clinical practice - Helen Hanson, Miranda Durkie, Fiona Lalloo, Louise Izatt, Terri P. McVeigh, Jackie A. Cook, Carole Brewer, James Drummond, Samantha Butler, Treena Cranston, Ruth Casey, Tricia Tan, Daniel Morganstein, Marc Tischkowitz, Clare Turnbull and Emma Roisin Woodward
Type: Article | 2022

Green synthesis of Ag nanoparticles using elm pod polysaccharide for catalysis and bacteriostasis - Mengmeng He, Zengsheng Han, Ying Liang, Han Zhao, Guanglong Ma, Yanshuai Cui and Longgang Wang
Type: Article | 2022

Type: Thesis | 2022 | University of Southampton

Type: Dataset | 2022 | University of Southampton

Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering - Franziska Heckel, Anna Turaj, Hayden Fisher, Claude Chan, Michael Marshall, Osman Dadas, Christine Penfold, Tatyana Inzhelevskaya, Christopher Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen Beers, Mark Cragg and Sean Lim
Type: Article | 2022

Type: Review | 2022

Type: Thesis | 2022 | University of Southampton

The impact of race and ethnicity in breast cancer: disparities and implications for precision oncology - Kelly A. Hirko, Gabrielle Rocque, Erica Reasor, Ammanuel Taye, Alex Daly, Ramsey I. Cutress, Ellen R. Copson, Dae-Won Lee, Kyung-Hun Lee, Seock-Ah Im and Yeon Hee Park
Type: Article | 2022

A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries - Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie and Christopher Mccormick
Type: Article | 2022

J

Targeting cancer-associated fibroblasts: Challenges, opportunities and future directions - Benjamin H. Jenkins, Josephine F. Buckingham, Christopher J. Hanley and Gareth J. Thomas
Type: Article | 2022

Body Mass Index and clinical outcome of severe COVID-19 patients with acute hypoxic respiratory failure: unravelling the “obesity paradox” phenomenon - Michael Jennings, Maria Burova, Laura G. Hamilton, Elsie Hunter, Clare Mordena, Ryan Beecham, Darshni Pandya, Helen Moyses, Kordo Saeed, Paul Afolabi, Philip Calder and Ahilanandan Dushianthan
Type: Article | 2022

K

Incubator type affects human blastocyst formation and embryo metabolism: a randomized controlled trial - Alexandra Kermack, Irina V. Fesenko, David R.G. Christensen, Kate Parry, Philippa Lowen, Susan J. Wellstead, Scott Harris, Philip Calder, Nicholas S Macklon and Franchesca D. Houghton
Type: Article | 2022

Reverse-transcription loop-mediated isothermal amplification has high accuracy for detecting severe acute respiratory syndrome coronavirus 2 in saliva and nasopharyngeal/oropharyngeal swabs from asymptomatic and symptomatic individuals - Stephen P. Kidd, Daniel Burns, Bryony Armson, Andrew D. Beggs, Emma L.A. Howson, Anthony Williams, Gemma Snell, Emma L. Wise, Alice Goring, Zoe Vincent-Mistiaen, Seden Grippon, Jason Sawyer, Claire Cassar, David Cross, Thomas Lewis, Scott M Reid, Samantha Rivers, Joe James, Paul Skinner, Ashley Banyard, Kerrie Davies, Anetta Ptasinska, Celina Whalley, Jack Ferguson, Claire Bryer, Charlie Poxon, Andrew Bosworth, Michael Kidd, Alex Richter, Jane Burton, Hannah Love, Sarah Fouch, Claire Tillyer, Amy Sowood, Helen Patrick, Nathan Moore, Michael Andreou, Nick Morant, Rebecca Houghton, Joe Parker, Joanne Slater-Jefferies, Ian Brown, Cosima Gretton, Zandra Deans, Deborah Porter, Nicholas J. Cortes, Angela Douglas, Sue L. Hill, Keith M. Godfrey and Veronica L. Fowler
Type: Article | 2022

Comparison of optimized methodologies for isolating nuclei from esophageal tissue - Lucy Kimbley, Rachel Parker, Jack Harrington, Robert, Charles Walker, Ben Grace, Jonathan West, Timothy Underwood and Matthew Rose-Zerilli
Type: Article | 2022

Type: Article | 2022

Dragon 1 Protocol Manuscript: Training, accreditation, implementation and safety evaluation of portal and hepatic vein embolization (PVE/HVE) to accelerate future liver remnant (FLR) hypertrophy - R Korenblik, B Olij, L A Aldrighetti, M Abu Hilal, M Ahle, B Arslan, L J van Baardewijk, I Baclija, C Bent, C L Bertrand, B Björnsson, M T de Boer, S W de Boer, R P H Bokkers, I H M Borel Rinkes, S Breitenstein, R C G Bruijnen, P Bruners, M W Büchler, J C Camacho, A Cappelli, U Carling, B K Y Chan, D H Chang, J Choi, J Codina Font, M Crawford, D Croagh, E Cugat, R Davis, D W De Boo, F De Cobelli, J F De Wispelaere, O M van Delden, M Delle, O Detry, R Díaz-Nieto, A Dili, J I Erdmann, O Fisher, C Fondevila, Å Fretland, F Garcia Borobia, A Gelabert, L Gérard, F Giuliante, P D Gobardhan, F Gómez, T Grünberger, D J Grünhagen, J Guitart, J Hagendoorn, J Heil, D Heise, E Herrero, G F Hess, M H Hoffmann, R Iezzi, F Imani, J Nguyen, E Jovine, J C Kalff, G Kazemier, T P Kingham, J Kleeff, O Kollmar, W K G Leclercq, S Lopez Ben, V Lucidi, A MacDonald, D C Madoff, S Manekeller, G Martel, A Mehrabi, H Mehrzad, M R Meijerink, K Menon, P Metrakos, C Meyer, A Moelker, S Modi, N Montanari, J Navines, U P Neumann, P Peddu, J N Primrose, X Qu, D Raptis, F Ratti, F Ridouani, C Rogan, U Ronellenfitsch, S Ryan, C Sallemi, J Sampere Moragues, P Sandström, L Sarriá, A Schnitzbauer, M Serenari, A Serrablo, M L J Smits, E Sparrelid, E Spüntrup, G A Stavrou, R P Sutcliffe, I Tancredi, J C Tasse, V Udupa, D Valenti, Y Fundora, T J Vogl, X Wang, S A White, W A Wohlgemuth, D Yu, I A J Zijlstra, C A Binkert, M H A Bemelmans, C van der Leij, E Schadde and R M van Dam
Type: Article | 2022

Type: Review | 2022

Type: Article | 2022

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The use of miRNAs in predicting response to neoadjuvant therapy in oesophageal cancer - Cameron C.J. Lang, Megan Lloyd, Said Alyacoubi, Saqib Rahman, Oliver John Pickering, Timothy Underwood and Stella P. Breininger
Type: Review | 2022

HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management - Matt Lechner, Jacklyn Liu, Liam Masterson and Tim R. Fenton
Type: Review | 2022

Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma - Matt Lechner, Yoko Takahashi, Mario Turri-Zanoni, Jacklyn Liu, Nicholas Counsell, Mario Hermsen, Raman Preet Kaur, Tianna Zhao, Murugappan Ramanathan, Volker H Schartinger, Oscar Emanuel, Sam Helman, Jordan Varghese, Jozsef Dudas, Herbert Riechelmann, Susanne Sprung, Johannes Haybaeck, David Howard, Nils Wolfgang Engel, Sarah Stewart, Jessica C Pickles, Thomas S Jacques, Tim R Fenton, Luke Williams, Francis M Vaz, Paul O'Flynn, Paul Stimpson, Simon Wang, S Alam Hannan, Samit Unadkat, Raghav Dwivedi, Cillian T Forde, Premjit Randhawa, Simon Gane, Jonathan Joseph, Peter J Andrews, Gary Royle, Alessandro Franchi, Roberta Maragliano, Simonetta Battocchio, Helen Bewicke-Copley, Christodoulos Pipinikas, Amy Webster, Chrissie Thirlwell, Debbie Ho, Andrew Teschendorff, Tianyu Zhu, Christopher D Steele, Nischalan Pillay, Bart Vanhaesebroeck, Ahmed Mohyeldin, Juan Fernandez-Miranda, Ki Wan Park, Quynh-Thu Le, Robert B West, Rami Saade, R Peter Manes, Sacit Bulent Omay, Eugenia M Vining, Benjamin L Judson, Wendell G Yarbrough, Maddalena Sansovini, Nicolini Silvia, Ilaria Grassi, Alberto Bongiovanni, David Capper, Ulrich Schüller, Selvam Thavaraj, Ann Sandison, Pavol Surda, Claire Hopkins, Marco Ferrari, Davide Mattavelli, Vittorio Rampinelli, Fabio Facchetti, Piero Nicolai, Paolo Bossi, Oswaldo A Henriquez, Kelly Magliocca, C Arturo Solares, Sarah K Wise, Jose L Llorente, Zara M Patel, Jayakar V Nayak, Peter H Hwang, Peter D Lacy, Robbie Woods, James P O'Neill, Amrita Jay, Dawn Carnell, Martin D Forster, Masaru Ishii, Nyall R London, Diana M Bell, Gary L Gallia, Paolo Castelnuovo, Stefano Severi, Valerie J Lund and Ehab Y Hanna
Type: Article | 2022

International multicenter study of clinical outcomes of sinonasal melanoma shows survival benefit for patients treated with immune checkpoint inhibitors and potential improvements to the current TNM staging system - Matt Lechner, Yoko Takahashi, Mario Turri-zanoni, Marco Ferrari, Jacklyn Liu, Nicholas Counsell, Davide Mattavelli, Vittorio Rampinelli, William Vermi, Davide Lombardi, Rami Saade, Ki Wan Park, Volker H. Schartinger, Alessandro Franchi, Carla Facco, Fausto Sessa, Simonetta Battocchio, Tim R. Fenton, Francis M. Vaz, Paul O'flynn, David Howard, Paul Stimpson, Simon Wang, S. Alam Hannan, Samit Unadkat, Jonathan Hughes, Raghav Dwivedi, Cillian T. Forde, Premjit Randhawa, Simon Gane, Jonathan Joseph, Peter J. Andrews, Manas Dave, Jason C. Fleming, David Thomson, Tianyu Zhu, Andrew Teschendorff, Gary Royle, Christopher Steele, Joaquin E. Jimenez, Jan Laco, Eric W. Wang, Carl Snyderman, Peter D. Lacy, Robbie Woods, James P. O'neill, Anirudh Saraswathula, Raman Preet Kaur, Tianna Zhao, Murugappan Ramanathan, Gary L. Gallia, Nyall R. London, Quynh-thu Le, Robert B. West, Zara M. Patel, Jayakar V. Nayak, Peter H. Hwang, Mario Hermsen, Jose Llorente, Fabio Facchetti, Piero Nicolai, Paolo Bossi, Paolo Castelnuovo, Amrita Jay, Dawn Carnell, Martin D. Forster, Diana M. Bell, Valerie J. Lund and Ehab Y. Hanna
Type: Article | 2022

Type: Article | 2022

Evaluating the immune response in treatment-naïve hospitalised patients with influenza and COVID-19 - Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F Vallejo, Stephen Poole, Nathan Brendish, Xiaofeng Dong, Catherine Hartley, John Holloway, Jane Lucas, Anthony Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P R Schofield, Paul Skipp, Julian A. Hiscox, Marta Polak, Tristan Clark and Diana Baralle
Type: Article | 2022

Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants - Hongyan Li, Christoph Engel, Miguel de la Hoya, Paolo Peterlongo, Drakoulis Yannoukakos, Luca Livraghi, Diana M. Eccles and David E. Goldgar
Type: Article | 2022

Zwitterionic sulfhydryl Sulfobetaine stabilized platinum nanoparticles for ernhanced Dopamine detection and antitumor ability - Ruyu Li, Liyuan Fan, Shengfu Chen, Longgang Wang, Yanshuai Cui, Guanglong Ma, Xiaoyu Zhang and Zhiwei Liu
Type: Article | 2022

Type: Letter | 2022

Type: Letter | 2022 | Item not available on this server.

Type: Other | 2022 | Item not available on this server.

Immune responses to SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO Study - Sean H. Lim, Beth Stuart, Debora Joseph-Pietras, Marina Johnson, Nicola Campbell, Adam Kelly, Danielle Jeffrey, Anna H Turaj, Kate Rolfvondenbaumen, Celine Galloway, Thomas Wynn, Adam R. Coleman, Benjamin Ward, Karen Long, Helen Coleman, Carina Mundy, Andrew T. Bates, Diana Ayres, Robert Lown, Janlyn Falconer, Oliver Brake, James Batchelor, Victoria Willimott, Anna Bowzyk Al-Naeeb, Lisa Robinson, Ann O'Callaghan, Graham P Collins, Tobias Menne, Saul N Faust, Christopher P Fox, Matthew Ahearne, Peter W M Johnson, Andrew J Davies and David Goldblatt
Type: Article | 2022

Optimisation of COVID‐19 diagnostic pathways in acute hospital admissions to prevent nosocomial transmission - Robert Livingstone, Alexander Woodhead, Megha Bhandari, James Dias, Trevor Smith, Tom Havelock and Matthew Stammers
Type: Article | 2022

Type: Article | 2022

Re-classification of clinically-detected sequence variants: framework for genetic clinicians and clinical scientists by CanVIG-UK (Cancer Variant Interpretation Group-UK) - Lucy Loong, Alice Garrett, Subin Choi, Miranda Durkie, Alison Callaway, James Drummond, Diana Eccles, Anneke Lucassen and Clare Turnbull
Type: Article | 2022

Type: Article | 2022

M

Type: Article | 2022

Lentinan stabilized bimetallic PdPt3 dendritic nanoparticles with enhanced oxidase-like property for L-cysteine detection - Ziyi Ma, Le Dong, Bingjie Zhang, Bo Liang, Liqiu Wang, Guanglong Ma and Longgang Wang
Type: Article | 2022

Comprehensive review on current controversies and debate in prostate artery embolization - Drew Maclean, Charles Timothy Francis Bryant, Ganesh Vigneswaran, Timothy Jc Bryant, Mark Harris, Bhaskar Somani and Sachin Modi
Type: Article | 2022

Type: Article | 2022

Type: Article | 2022

Cancer prevention with resistant starch in lynch syndrome patients in the CAPP2-randomized placebo controlled trial: Planned 10-year follow-up - John C. Mathers, Faye Elliott, Finlay Macrae, Jukka-pekka Mecklin, Gabriela Möslein, Fiona E. Mcronald, Lucio Bertario, D. Gareth Evans, Anne-marie Gerdes, Judy W.c. Ho, Annika Lindblom, Patrick J. Morrison, Jem Rashbass, Raj S. Ramesar, Toni T. Seppälä, Huw J.w. Thomas, Harsh J. Sheth, Kirsi Pylvänäinen, Lynn Reed, Gillian M. Borthwick, D. Timothy Bishop and John Burn
Type: Article | 2022

Type: Dataset | 2022 | University of Southampton

Compassionate use of Pulmonary Vasodilators in Acute Severe Hypoxic Respiratory Failure due to COVID-19 - Lewis Matthews, Laurence Baker, Matteo Ferrari, Weronika Sanchez, John Pappachan, Mike Pw Grocott, Ahilanandan Dushianthan, Thomas Wilkinson, Hannah Burke, Anna Freeman, Michael Celinski, Saul Faust, Gareth Thomas and Christopher Kipps
Type: Article | 2022

ATM regulates differentiation of myofibroblastic cancer-associated fibroblasts and can be targeted to overcome immunotherapy resistance - Massimiliano Mellone, Klaudia Piotrowska, VENTURI GIULIA, Lija James, Aleksandra Bzura, Maria-Antoinette Lopez, Sonya James, Chuan Wang, Matthew Ellis, Christopher Hanley, Josephine F. Buckingham, Kerry Cox, Gareth Hughes, Viia Valge-Archer, Emma King, Stephen Beers, Vincent Jaquet, George Jones, Natalia Savelyeva, A. Emre Sayan, Jason Parsons, Stephen Durant and Gareth Thomas
Type: Article | 2022

O44 new GI bleed nursing model & unit changes outcomes - Matilda Mills, Ben Glover, Mahmoud Abosamra, Patrick Warren, Sara Ahmadi, Gillian Lambert, Nanette Kinnaird, Mark Wright, Philip Boger and Matt Stammers
Type: Meeting abstract | 2022 | Item not available on this server.

Type: Thesis | 2022 | University of Southampton

B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells - Annabel Rachel Minton, Lindsay D. Smith, Dean J. Bryant, Jonathan Strefford, Francesco Forconi, Freda Stevenson, David Tumbarello, Edd James, Geir Åge Løset, Ludvig A. Munthe, Andrew J. Steele and Graham Packham
Type: Article | 2022

Type: Dataset | 2022 | University of Southampton

Long-term benefit of IGHV mutated patients in a real-life multicenter cohort of FCR-treated chronic lymphocytic leukemia - Riccardo Moia, Riccardo Dondolin, Maria Stefania De Propris and Francesco Forconi
Type: Letter | 2022 | Item not available on this server.

The MARECA (national study of management of breast cancer locoregional recurrence and oncological outcomes) study: National Practice Questionnaire of United Kingdom multi-disciplinary decision making - J. Morgan, V. Cheng, P. Barry, Ellen Copson, Ramsey Cutress, R Dave, B Elsberger, P Fairbrother, S Hartup, B Hogan, K Horgan, C C Kirwan, S A McIntosh, R L O'Connell, N Patani, S Potter, T Rattay, L Sheehan, L Wyld and B Kim
Type: Article | 2022

Person-based co-design of a decision aid template for people with a genetic predisposition to cancer - Kate Morton, Kelly Kohut, Lesley Turner, Sian Smith, Emma J. Crosbie, Neil Ryan, Chloe Grimmett, Diana M. Eccles and Claire Foster
Type: Article | 2022

Type: Review | 2022 | Item availability restricted.

N

Utility of KI-67 as a prognostic biomarker in pulmonary neuroendocrine neoplasms: a systematic review and meta-analysis - Salma Naheed, Chloe Holden, Lulu Tanno, Linda Pattini, Neil W Pearce, Bryan Green, Eleanor Jaynes, Judith Cave, Christian H Ottensmeier and Giuseppe Pelosi
Type: Article | 2022

Identification of neoantigens in oesophageal adenocarcinoma - Ben Nicholas, Alistair Bailey, Katy J. McCann, Oliver Wood, Robert C Walker, Robert Parker, Nicola Ternette, Tim Elliott, Tim J Underwood, Peter Johnson and Paul Skipp
Type: Article | 2022

Analysis of cell‐specific peripheral blood biomarkers in severe allergic asthma identifies innate immune dysfunction - Ben Nicholas, Jane Guo, Hyun‐Hee Lee, Alistair Bailey, Rene de Waal Malefyt, Milenko Cicmil and Ratko Djukanovic
Type: Letter | 2022

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands - Benjamin Nicholas, Alistair Bailey, Karl J. Staples, Thomas Wilkinson, Timothy Elliott and Paul Skipp
Type: Article | 2022

O

The first international Delphi consensus statement on Laparoscopic Gastrointestinal surgery - Islam Omar, Karl Miller, Brijesh Madhock, Bassem Amr, rishi Singhal, Yitka Graham, Sjaak Pouwels, Mohammad Abu Hilal, Sandeep Aggarwal, Irfan Ahmed, Ali Aminian, Basil Jaser Ammori, Tan Arulampalam, Altaf Awan, Jose Maria Balibrea, Aneel Bahangu, Richard Brady, wendy Brown, Manish Chand, Ara Darzi, Talvinder Singh Gill, Ramen Goel, Bussa R Gopinath, Mark van Berge Henegouwen, Jacques M Himpens, David Kerrigan, Misha Luyer, Christian Macutkiewicz, Julio Mayol, Sanjay Purkayastha, Raul Jacobo Rosenthal, Scott Shikora, Peter Kenneth Small, Neil James Smart, Mark A Taylor, Tehemton Udwadia, Timothy Underwood, Yirupaiahgari Viswanath, Neil Thomas Welch, Steven D Wexner, Michael Samual James Wilson, Des C Winter and Kamal K Mahawar
Type: Article | 2022

Pancreas deficiency modifies bone development in the ovine fetus near term - Richard Oreffo, Stuart Lanham, Abigail L. Fowden and Alison J. Forhead
Type: Article | 2022

Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility - Christian M. Orr, Hayden Fisher, Xiaojie Yu, Claude H.T. Chan, Yunyun Gao, Patrick Duriez, Steven Booth, Isabel, Grace Elliott, Tatyana Inzhelevskaya, Christopher Mockridge, Christine Penfold, Armin Wagner, Martin Glennie, Ann L White, Jonathan W. Essex, Arwen R. Pearson, Mark Cragg and Ivo Tews
Type: Article | 2022

The genomics of hairy cell Leukaemia and splenic diffuse red pulp Lymphoma - David Oscier, Kostas Stamatopoulos, Amatta Mirandari and Jonathan Strefford
Type: Review | 2022

P

Type: Thesis | 2022 | University of Southampton | Item availability restricted.

Type: Article | 2022 | Item not available on this server.

Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy - Sara Pereira, Guanglong Ma, Li Na, Samo Hudoklin, Mateja E. Kreft, Nina Kostevsek and Wafa T. Al-Jamal
Type: Article | 2022

Learning curve for adoption of robot-assisted minimally invasive esophagectomy: a systematic review of oncological, clinical, and efficiency outcomes - Oliver J. Pickering, Gijs I. Van Boxel, Nick C. Carter, Stuart J. Mercer, Benjamin C. Knight and Philip H. Pucher
Type: Article | 2022

R

TP53 Abnormalities are underlying the poor outcome associated with chromothripsis in chronic lymphocytic Leukemia patients with complex karyotype - Silvia Ramos-campoy, Anna Puiggros, Joanna Kamaso, Sílvia Beà, Sandrine Bougeon, María José Larráyoz, Dolors Costa, Helen Parker, Gian Matteo Rigolin, María Laura Blanco, Rosa Collado, Idoya Ancín, Rocío Salgado, Marco A. Moro-García, Tycho Baumann, Eva Gimeno, Carolina Moreno, Marta Salido, Xavier Calvo, María José Calasanz, Antonio Cuneo, Florence Nguyen-Khac, David Oscier, Claudia Haferlach, Jonathan Strefford, Jacqueline Schoumans and Blanca Espinet Sola
Type: Article | 2022

Type: Article | 2022 | Item availability restricted.

Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features - Pauline Robbe, Kate E. Ridout, Dimitrios V. Vavoulis, Helene M.P. Dreau, Ben Kinnersley, Nicholas Denny, Daniel Chubb, Niamh Appleby, Anthony Cutts, Alex J. Cornish, Laura Lopez-Pascua, Ruth Clifford, Adam Burns, Basile Stamatopoulos, Maite Cabes, Reem Alsolami, Pavlos Antoniou, Melanie Oates, Doriane Cavalieri, Jane Gibson, Anika V. Prabhu, Ron Schwessinger, Daisy Jennings, Terena James, Uma Maheswari, Martí Duran-Ferrer, Piero Carninci, Samantha J.L. Knight, Robert Månsson, Jim R. Hughes, James Davies, Mark Ross, David Bentley, Jonathan Strefford, Stephen Devereux, Andrew R. Pettitt, Peter Hillmen, Mark J. Caulfield, Richard S. Houlston, José Ignacio Martín-Subero and Anna Schuh
Type: Article | 2022

Fc-γ receptor-mediated crosslinking co-defines the immunostimulatory activity of anti-human CD96 antibodies - Anne Rogel, Fathima M Ibrahim, Stephen Thirdborough, Florence Renart-Depontieu, Charles Birts, Sarah Buchan, Xavier Preville, Emma King and Aymen Al-Shamkhani
Type: Article | 2022 | Item availability restricted.

Type: Review | 2022

S

Type: Thesis | 2022 | University of Southampton | Item availability restricted.

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors - Rita K. Schmutzler, Bjorn Schmitz-Luhn, Bettina Borisch, Peter Devilee, Diana Eccles, Per Hall, Judith Balmaña, Stefania Boccia, Peter Dabrock, Günter Emons, Wolfgang Gaissmaier, Jacek Gronwald, Stefanie Houwaart, Stefan Huster, Karin Kast, Alexander Katalinic, Sabine C. Linn, Gert Matthijs, Sowmiya Moorthie, Paul Pharoah, Kerstin Rhiem, Tade Spranger, Dominique Stoppa-Lyonnet, Johannes Jozef Marten van Delden, Marc van den Bulcke and Christiane Woopen
Type: Review | 2022

Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts - Benjamin P. Sharpe, Annette Hayden, Antigoni Manousopoulou, Andrew Cowie, Robert C. Walker, Jack Harrington, Fereshteh Izadi, Stella P. Breininger, Jane Gibson, Oliver Pickering, Eleanor Jaynes, Ewan Kyle, John H. Saunders, Simon L. Parsons, Alison A. Ritchie, Philip A. Clarke, Pamela Collier, Nigel P. Mongan, David O. Bates, Kiren Yacqub-Usman, Spiros D. Garbis, Zoë Walters, Matthew Rose-Zerilli, Anna M. Grabowska and Timothy J. Underwood
Type: Article | 2022

Type: Thesis | 2022 | University of Southampton | Item availability restricted.

Minimally invasive versus open liver resection for hepatocellular carcinoma in the elderly: international multicentre propensity score-matched study - Jasper P. Sijberden, Federica Cipriani, Jacopo Lanari, Nadia Russolillo, Andrea Benedetti Cacciaguerra, Daniel Osei-Bordom, Simone Conci, Burak Görgec, John N. Primrose, Bjørn Edwin, Santi López-Ben, Mathieu D'Hondt, Fernando Rotellar, Marc G. Besselink, Ibrahim Dagher, Felice Giuliante, David Fuks, Renzo Rozzini, Andrea Ruzzenente, Robert P. Sutcliffe, Marco Vivarelli, Alessandro Ferrero, Umberto Cillo, Luca A. Aldrighetti and Mohammad Abu Hilal
Type: Article | 2022 | Item availability restricted.

Type: Thesis | 2022 | University of Southampton

FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms - Alexander Patrick Simpson, Ali Roghanian, Robert James Oldham, Claude Chan, Christine Penfold, Sonya James, Yury Bogdanov, Christopher Mockridge, Hyung Kim, Tatyana Inzhelevskaya, Stephen Beers and Mark Cragg
Type: Article | 2022

Association of Upper Gastrointestinal Surgery of Great Britain and Ireland (AUGIS)/Perioperative Quality Initiative (POQI) consensus statement on intraoperative and postoperative interventions to reduce pulmonary complications after oesophagectomy - Pritam Singh, James Gossage, Sheraz Markar, Philip H Pucher, Alex Wickham, Jonathan Weblin, Swathikan Chidambaram, Alexander Bull, Oliver Pickering, Monty Mythen, Nick Maynard, Mike Grocott and Tim Underwood
Type: Article | 2022

Type: Thesis | 2022 | University of Southampton

ELEVATE - evaluating Temozolomide and Nivolumab in patients with advanced unresectable previously treated oesophagogastric adenocarcinoma with MGMT methylation: study protocol for a single arm phase II trial - Elizabeth Smyth, Kelly Cozens, Daniel Griffiths, Kathryn L Clark, Sean Ewings, Russell Petty, Tim Underwood, Rebecca C Fitzgerald, James Tanner, Olivier Giger, Shubha Anand and Gareth Griffiths
Type: Article | 2022

International validation of the EORTC QLQ-ANL27, a field study to test the anal cancer-specific health-related quality of life questionnaire - Samantha Sodergren, Colin Johnson, Anne-Sophie Darlington, Karen Nugent, Alexandra Gilbert, Kim Cocks, Marianne Grønlie Guren, Eleonor Rivin del Campo, Christine Brennan, Peter Christensen, William Chu, Hans Chung, Kristopher Dennis, Duncan C. Gilbert, Rob Glynne-Jones, Michaeel Jefford, Mia Johansson, Anders Johnsson, Therese Juul, Dimitrios Kardamakis, Julia Lai-Kwon, Vicky McFarlane, Isalia M.C. Miguel, Karen Nugent, Femke Peters, Rachel P. Riechelmann, Nazim S. Turhal, Shun Wong and Vassilios Vassiliou
Type: Article | 2022

A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy - Liam Spurr, Carlos Martinez, Rohan Katipally, Soumya Iyer, Siân A. Pugh, John Bridgewater, John Primrose, Enric Domingo, Timothy Maughan, Michael D’Angelica, Mark Talamonti, Mitchell Posner, Philip Connell, Ralph Weichselbaum and Sean Pitroda
Type: Article | 2022

P319 natural language processing and named entity recognition in inflammatory bowel disease referrals - Matt Stammers, Michael George, Constantinos Regas, Georgia May, Sohail Rahmany, Cai Davis, Florina Borca, Will Knibbs, Vishnu V. Chandrabalan and Markus Gwiggner
Type: Meeting abstract | 2022 | Item not available on this server.

Impact of direct-access IBD physician delivered endoscopy on clinical outcomes: a pre-implementation and post-implementation study - Matt Stammers, Sohail Rahmany, Louise Downey, Florina Borca, Clare Harris, Richard Harris, Martin McDonnell, Stephanie Sartain, Nicolas Coleman, Bernard Stacey, Trevor Smith, Fraser Cummings, Richard Felwick and Markus Gwiggner
Type: Article | 2022

Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C - Joseph Richard Stephenson Clarke, Leon R Douglas, Patrick Duriez, Dimitrios-Ilias Balourdas, Andreas C. Joerger, Raniya Khadiullina, Emil Bulatov and Matthias G.J. Baud
Type: Article | 2022

Final results of neoadjuvant atezolizumab in cisplatin-ineligible patients with muscle-invasive urothelial cancer of the bladder - Bernadett Szabados, Mark Kockx, Zoe June Assaf, Pieter-Jan van Dam, Alejo Rodriguez-Vida, Ignacio Duran, Simon J Crabb, Michiel S Van Der Heijden, Albert Font Pous, Gwenaelle Gravis, Urbano Anido Herranz, Andrew Protheroe, Alain Ravaud, Denis Maillet, Maria Jose Mendez, Cristina Suarez, Mark Linch, Aaron Prendergast, Charlotte Tyson, Diana Stanoeva, Sofie Daelemans, Miche Rombouts, Sanjeev Mariathasan, Joy S Tea, Kelly Mousa, Shruti Sharma, Alexey Aleshin, Romain Banchereau, Daniel Castellano and Thomas Powles
Type: Article | 2022

Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1 - Katarzyna Szymanska, Karsten Boldt, Clare V Logan, Matthew Adams, Philip A Robinson, Marius Ueffing, Elton Zeqiraj, Gabrielle Wheway and Colin A Johnson
Type: Article | 2022

T

Conditional inference tree models to perceive depth of invasion in T1 colorectal cancer - Hiroyuki Takamaru, Matthew Stammers, Fumito Yanagisawa, Yasuhiko Mizuguchi, Masau Sekiguchi, Masayoshi Yamada, Taku Sakamoto, Takahisa Matsuda and Yutaka Saito
Type: Article | 2022 | Item availability restricted.

Type: Dataset | 2022 | University of Southampton

B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells - Joe Taylor, Sarah Wilmore, Sophie Marriot, Karly-Rai Rogers-Broadway, Rachel Fell, Annabel R. Minton, Tom Branch, Meg Ashton-Key, Mark Coldwell, Freda K. Stevenson, Francesco Forconi, Andrew J. Steele, Graham Packham and Alison Yeomans
Type: Article | 2022

A machine-learning approach to predict upper gastrointestinal multidisciplinary team treatment decisions - Navamayooran Thavanesan, Ganesh Vigneswaran, Saqib Rahman and Tim Underwood
Type: Conference or Workshop Item | 2022

U

Type: Article | 2022

V

Temporal evolution in quality of life following melphalan percutaneous hepatic perfusion for patients with metastatic uveal melanoma - Ganesh Vigneswaran, Pippa Woodcock, Tom Gibson, Shian Patel, Maryam Adil, Matthew Wheater, Ioannis Karydis, Sanjay Gupta, Brian Stedman and Sachin Modi
Type: Meeting abstract | 2022 | Item not available on this server.

Type: Dataset | 2022 | University of Southampton

Type: Article | 2022

W

Clinical phenotype and management of severe neurotoxicity observed in patients with neuroblastoma treated with dinutuximab beta in clinical trials - Aleksandra Wieczorek, Carla Manzitti, Alberto Garaventa, Juliet Gray, Vassilios Papadakis, Dominique Valteau-Couanet, Katarzyna Zachwieja, Ulrike Poetschger, Ingrid Pribill, Stefan Fiedler, Ruth Ladenstein and Holger Lode
Type: Article | 2022

Clinical significance of serum albumin and implications of FcRn inhibitor treatment in IgG-mediated autoimmune disorders - E. Sally Ward, Deborah Gelinas, Erwin Dreesen, Jolien Van Santbergen, Jan Terje Andersen, Nicholas J. Silvestri, Joseph E. Kiss, Darrell Sleep, Daniel J. Rader, John J. P. Kastelein, Els Louagie, Gestur Vidarsson and Isabel Spriet
Type: Article | 2022

Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma - Emily Rose Webb, Julia Moreno Vicente, Alistair Easton, Silvia Lanati, Martin Taylor, Sonya James, Emily L. Williams, Christine Penfold, Stephen Beers, Juliet Gray and Vikki English
Type: Article | 2022

Type: Article | 2022

The Wessex Fit-4-Cancer Surgery Trial (WesFit): a protocol for a factorial-design, pragmatic randomised-controlled trial investigating the effects of a multi-modal prehabilitation programme in patients undergoing elective major intra–cavity cancer surgery - Malcolm West, Andrew Bates, Chloe Grimmett, Cait Allen, Richard Green, Lesley Hawkins, Helen Moyses, Samantha Leggett, Denny Z H Levett, Sally Rickard, Judit Varkonyi-sepp, Fran Williams, Stephen Wootton, Matthew Hayes, Michael P W Grocott and Sandy Jack
Type: Article | 2022

Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments - Jane Willoughby, Juliet Gray, Stephen Beers, Julia Moreno vicente and Jane Willoughby
Type: Article | 2022

Type: Article | 2022 | Item not available on this server.

P318 electronic referral grading system that puts patients and clinicians first - Samuel Wood, Megha Bhandari, Florina Borca, Liz Barnes, Ben Hendy, Nicholas Coleman, Bernard Stacey, Richard Felwick, Matt Stammers and Markus Gwiggner
Type: Meeting abstract | 2022 | Item not available on this server.

Z

Indications, trends, and perioperative outcomes of minimally invasive and open liver surgery in non-obese and obese patients: an international multicentre propensity score matched retrospective cohort study of 9963 patients - Giuseppe Zimmitti, Jasper P. Sijberden, Daniel Osei-Bordom, Nadia Russolillo, Davit Aghayan, Jacopo Lanari, Federica Cipriani, Santi López-Ben, Fernando Rotellar, David Fuks, Mathieu D'Hondt, John N. Primrose, Burak Görgec, Andrea Benedetti Cacciaguerra, Ravi Marudanayagam, Serena Langella, Marco Vivarelli, Andrea Ruzzenente, Marc G. Besselink, Adnan Alseidi, Mikhail Efanov, Felice Giuliante, Ibrahim Dagher, Elio Jovine, Fabrizio di Benedetto, Luca A. Aldrighetti, Umberto Cillo, Bjørn Edwin, Alessandro Ferrero, Robert P. Sutcliffe and Mohammed Abu Hilal
Type: Article | 2022

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