Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences
Cancer Sciences" and Year is 2022
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Number of items: 49.
Article
Clinical phenotype and management of severe neurotoxicity observed in patients with neuroblastoma treated with dinutuximab beta in clinical trials - Aleksandra Wieczorek, Carla Manzitti, Alberto Garaventa, Juliet Gray, Vassilios Papadakis, Dominique Valteau-Couanet, Katarzyna Zachwieja, Ulrike Poetschger, Ingrid Pribill, Stefan Fiedler, Ruth Ladenstein and Holger Lode
Type: Article
| 2022
Deleterious genetic variation across the NOD-signaling pathway is associated with reduced NFKB-signaling transcription and upregulation of alternative inflammatory transcripts in paediatric inflammatory bowel disease - James Ashton, Konstantinos Boukas, Imogen, Sian Stafford, Guo Cheng, Rachel Haggarty, Tracy Coelho, Akshay Batra, Nadeem A. Afzal, Anthony Williams, Marta Polak, R. Mark Beattie and Sarah Ennis
Type: Article
| 2022
Changes in the management of patients having radical radiotherapy for lung cancer during the first wave of the COVID-19 pandemic in the UK - K. Banfill, W. Croxford, I. Fornacon-Wood, K. Wicks, S. Ahmad, A. Britten, C. Carson, N. Dorey, M Hatton, C. Hiley, K. Thippu Jayaprakash, A. Jegannathen, P. Koh, N. Panakis, C. Peedell, A. Pope, C. Powell, C. Stilwell, B. Thomas, E. Toy, V. Wood, S. Yahya, S.Y. Zhou, G. Price and C. Faivre-Finn
Type: Article
| 2022
Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles - Rahul Bhome, Muhammad Emaduddin, Massimiliano Mellone, Stephen Thirdborough, John Primrose, Gareth Thomas, Alexander Mirnezami and Abdulkadir Emre Sayan
Type: Article
| 2022
Long term outcomes and exploratory analyses of the randomised phase 3 BILCAP study - John Bridgewater, Peter Fletcher, Daniel H. Palmer, Hassan Z. Malik, Raj Prasad, Darius Mirza, Alan Anthony, Pippa G. Corrie, Stephen Falk, Meg Finch-Jones, Harpreet Wasan, Paul J. Ross, Lucy Wall, Jonathan Wadsley, Thomas R Jeffry Evans, Deborah D. Stocken, Clive Stubbs, Raaj Praseedom, Yuk Ting Ma, Brian Davidson, John P. Neoptolemos, Timothy Iveson, David Cunningham, O James Garden, Juan W. Valle and John Primrose
Type: Article
| 2022
| Item availability restricted.
Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results - N Bundred, N Porta, A Murray Brunt, A Cramer, A Hanby, A M Shaaban, E A Rakha, A Armstrong, Ramsey Cutress, D Dodwell, M A Emson, A Evans, S M Hartup, K Horgan, S E Miller, S A McIntosh, J P Morden, J Naik, S Narayanan, J Ooi, A I Skene, D A Cameron and J M Bliss
Type: Article
| 2022
High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in CLL patients - Giorgia Chiodin, Francesco Forconi, Isla Henderson, Luis Del Rio Fernandez, Ian Tracy, Helen Parker, Jonathan Strefford, Jade Forster, Nora Potter, Benjamin Sale, Stuart Lanham, Freda Stevenson, Enrica Antonia Martino, Laura Ondrisova, Annalisa D'Avola, Silvia Bonfiglio, Lydia Scarfo, Lesley-Ann Sutton, Oliver Brake, Marek Mraz, Paolo Ghia and Samantha J. Drennan
Type: Article
| 2022
| Item availability restricted.
Systemic inflammation accelerates changes in microglial and synaptic markers in an experimental model of chronic neurodegeneration - Joe K. Chouhan, Ursula Püntener, Jessica Teeling and Steven Booth
Type: Article
| 2022
Prognostic effect of body mass index in patients with advanced NSCLC treated with chemoimmunotherapy combinations - Alessio Cortellini, Biagio Ricciuti, Victor R. Vaz, Davide Soldato, Joao V. Alessi, Filippo G. Dall'olio, Giuseppe L. Banna, Sethupathi Muthuramalingam, Samuel Chan, Margarita Majem, Aida Piedra, Giuseppe Lamberti, Elisa Andrini, Alfredo Addeo, Alex Friedlaender, Francesco Facchinetti, Teresa Gorriá, Laura Mezquita, Delphine Hoton, Lacroix Valerie, Frank Aboubakar Nana, James Artingstall, Charles Comins, Massimo Di Maio, Andrea Caglio, Judith Cave, Hayley McKenzie, Thomas Newsom-Davis, Joanne S. Evans, Marcello Tiseo, Antonio D'Alessio, Claudia A.M. Fulgenzi, Benjamin Besse, Mark M. Awad and David J. Pinato
Type: Article
| 2022
Role of the circadian clock “Death-Loop” in the DNA damage response underpinning cancer treatment resistance - Mark Cragg
Type: Article
| 2022
(SUMO)-Wrestling with Rituximab - Mark Cragg
Type: Article
| 2022
| Item availability restricted.
HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy - Mark Cragg, Stephen Beers, Khiyam Hussain, Kirstie Cleary, Robert Oldham, Russell Foxall, Sonya James, Steven Booth, Jemma Longley, Richard J Stopforth, Ali Roghanian and Matthew Carter
Type: Article
| 2022
From theory to practice: an international approach to establishing prehabilitation programmes - June F. Davis, Stefan J. Van Rooijen, Chloe Grimmett, Malcom A. West, Anna M. Campbell, Rashami Awasthi, Gerrit D. Slooter, Michael P. Grocott, Franco Carli and Sandy Jack
Type: Article
| 2022
High likelihood of actionable pathogenic variant detection in breast cancer genes in women with very early onset breast cancer - D. Gareth Evans, Elke M. van Veen, Helen J. Byers, Sarah J. Evans, George J. Burghel, Emma R. Woodward, Elaine F. Harkness, Diana Eccles, Stephanie L. Greville-Haygate, Jamie M. Ellingford, Naomi L. Bowers, Marta Pereira, Andrew J. Wallace, Sasha J. Howell, Anthony Howell, Fiona Lalloo, William G. Newman and Miriam Jane Smith
Type: Article
| 2022
The impact of endoscopic ultrasound on the management and outcome of patients with oesophageal cancer: an update of a systematic review - K. G. Foley, J. Franklin, C. M. Jones, B. Coles, S. A. Roberts, T. J. Underwood and T. Crosby
Type: Article
| 2022
| Item availability restricted.
Biological and clinical insight from analysis of the tumor B-cell 2 receptor structure and function in chronic lymphocytic Leukemia - Francesco Forconi, Stuart Lanham and Giorgia Chiodin
Type: Article
| 2022
Quantifying evidence towards pathogenicity for rare phenotypes: the case of succinate dehydrogenase genes SDHB and SDHD - A Garrett, C Loveday, L King, S Butler, R Robinson, C Horton, et al., Diana Eccles and Clare Turnbull
Type: Article
| 2022
Type: Article
| 2022
| Item availability restricted.
Platinum-based chemotherapy ‘Rechallenge’ in advanced non-ovarian solid malignancies - Joanna Hack and Simon Crabb
Type: Article
| 2022
UK recommendations for SDHA germline genetic testing and screening in clinical practice - Helen Hanson, Miranda Durkie, Fiona Lalloo, Louise Izatt, Terri P. McVeigh, Jackie A. Cook, Carole Brewer, James Drummond, Samantha Butler, Treena Cranston, Ruth Casey, Tricia Tan, Daniel Morganstein, Marc Tischkowitz, Clare Turnbull and Emma Roisin Woodward
Type: Article
| 2022
Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering - Franziska Heckel, Anna Turaj, Hayden Fisher, H.T. Claude Chan, Michael J.E. Marshall, Osman Dadas, Christine A. Penfold, Tatyana Inzhelevskaya, C. Ian Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen Beers, Mark Cragg and Sean Lim
Type: Article
| 2022
A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries - Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie and Christopher Mccormick
Type: Article
| 2022
| Item availability restricted.
Reverse-transcription loop-mediated isothermal amplification has high accuracy for detecting severe acute respiratory syndrome coronavirus 2 in saliva and nasopharyngeal/oropharyngeal swabs from asymptomatic and symptomatic individuals - Stephen P Kidd, Daniel Burns, Bryony Armson, Andrew D Beggs, Emma L A Howson, Anthony Williams, Gemma Snell, Emma L Wise, Alice Goring, Zoe Vincent-Mistiaen, Seden Grippon, Jason Sawyer, Claire Cassar, David Cross, Thomas Lewis, Scott M Reid, Samantha Rivers, Joe James, Paul Skinner, Ashley Banyard, Kerrie Davies, Anetta Ptasinska, Celina Whalley, Jack Ferguson, Claire Bryer, Charlie Poxon, Andrew Bosworth, Michael Kidd, Alex Richter, Jane Burton, Hannah Love, Sarah Fouch, Claire Tillyer, Amy Sowood, Helen Patrick, Nathan Moore, Michael Andreou, Nick Morant, Rebecca Houghton, Joe Parker, Joanne Slater-Jefferies, Ian Brown, Cosima Gretton, Zandra Deans, Deborah Porter, Nicholas J Cortes, Angela Douglas, Sue L Hill, Keith M Godfrey and Veronica L Fowler
Type: Article
| 2022
Comparison of optimised methodologies for isolating nuclei from esophageal tissue - Lucy Kimbley, Rachel Parker, Jack Harrington, Robert, Charles Walker, Ben Grace, Jonathan West, Timothy Underwood and Matthew Rose-Zerilli
Type: Article
| 2022
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma - Matt Lechner, Yoko Takahashi, Mario Turri-Zanoni, Jacklyn Liu, Nicholas Counsell, Mario Hermsen, Raman Preet Kaur, Tianna Zhao, Murugappan Ramanathan, Volker H Schartinger, Oscar Emanuel, Sam Helman, Jordan Varghese, Jozsef Dudas, Herbert Riechelmann, Susanne Sprung, Johannes Haybaeck, David Howard, Nils Wolfgang Engel, Sarah Stewart, Jessica C Pickles, Thomas S Jacques, Tim R Fenton, Luke Williams, Francis M Vaz, Paul O'Flynn, Paul Stimpson, Simon Wang, S Alam Hannan, Samit Unadkat, Raghav Dwivedi, Cillian T Forde, Premjit Randhawa, Simon Gane, Jonathan Joseph, Peter J Andrews, Gary Royle, Alessandro Franchi, Roberta Maragliano, Simonetta Battocchio, Helen Bewicke-Copley, Christodoulos Pipinikas, Amy Webster, Chrissie Thirlwell, Debbie Ho, Andrew Teschendorff, Tianyu Zhu, Christopher D Steele, Nischalan Pillay, Bart Vanhaesebroeck, Ahmed Mohyeldin, Juan Fernandez-Miranda, Ki Wan Park, Quynh-Thu Le, Robert B West, Rami Saade, R Peter Manes, Sacit Bulent Omay, Eugenia M Vining, Benjamin L Judson, Wendell G Yarbrough, Maddalena Sansovini, Nicolini Silvia, Ilaria Grassi, Alberto Bongiovanni, David Capper, Ulrich Schüller, Selvam Thavaraj, Ann Sandison, Pavol Surda, Claire Hopkins, Marco Ferrari, Davide Mattavelli, Vittorio Rampinelli, Fabio Facchetti, Piero Nicolai, Paolo Bossi, Oswaldo A Henriquez, Kelly Magliocca, C Arturo Solares, Sarah K Wise, Jose L Llorente, Zara M Patel, Jayakar V Nayak, Peter H Hwang, Peter D Lacy, Robbie Woods, James P O'Neill, Amrita Jay, Dawn Carnell, Martin D Forster, Masaru Ishii, Nyall R London, Diana M Bell, Gary L Gallia, Paolo Castelnuovo, Stefano Severi, Valerie J Lund and Ehab Y Hanna
Type: Article
| 2022
| Item availability restricted.
Evaluating the immune response in treatment-naïve hospitalised patients with influenza and COVID-19 - Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F Vallejo, Stephen Poole, Nathan Brendish, Xiaofeng Dong, Catherine Hartley, John Holloway, Jane Lucas, Anthony Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P R Schofield, Paul Skipp, Julian A. Hiscox, Marta Polak, Tristan Clark and Diana Baralle
Type: Article
| 2022
| Item availability restricted.
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants - Hongyan Li, Christoph Engel, Miguel de la Hoya, Paolo Peterlongo, Drakoulis Yannoukakos, Luca Livraghi, Diana M. Eccles and David E. Goldgar
Type: Article
| 2022
Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study - Sean H. Lim, Beth Stuart, Debora Joseph-Pietras, Marina Johnson, Nicola Campbell, Adam Kelly, Danielle Jeffrey, Anna H Turaj, Kate Rolfvondenbaumen, Celine Galloway, Thomas Wynn, Adam R. Coleman, Benjamin Ward, Karen Long, Helen Coleman, Carina Mundy, Andrew T. Bates, Diana Ayres, Robert Lown, Janlyn Falconer, Oliver Brake, James Batchelor, Victoria Willimott, Anna Bowzyk Al-Naeeb, Lisa Robinson, Ann O'Callaghan, Graham P Collins, Tobias Menne, Saul N Faust, Christopher P Fox, Matthew Ahearne, Peter W M Johnson, Andrew J Davies and David Goldblatt
Type: Article
| 2022
Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants - Lucy Loong, Cankut Cubuk, Subin Choi, Sophie Allen, Beth Torr, Alice Garrett and et al.
Type: Article
| 2022
Re-classification of clinically-detected sequence variants: framework for genetic clinicians and clinical scientists by CanVIG-UK (Cancer Variant Interpretation Group-UK) - Lucy Loong, Alice Garrett, Subin Choi, Miranda Durkie, Alison Callaway, James Drummond and Clare Turnbull
Type: Article
| 2022
The MARECA (national study of management of breast cancer locoregional recurrence and oncological outcomes) study: National Practice Questionnaire of United Kingdom multi-disciplinary decision making - J. Morgan, V. Cheng, P. Barry, Ellen Copson, Ramsey Cutress, R Dave, B Elsberger, P Fairbrother, S Hartup, B Hogan, K Horgan, C C Kirwan, S A McIntosh, R L O'Connell, N Patani, S Potter, T Rattay, L Sheehan, L Wyld and B Kim
Type: Article
| 2022
| Item availability restricted.
Utility of KI-67 as a prognostic biomarker in pulmonary neuroendocrine neoplasms: a systematic review and meta-analysis - Salma Naheed, Chloe Holden, Lulu Tanno, Linda Pattini, Neil W Pearce, Bryan Green, Eleanor Jaynes, Judith Cave, Christian H Ottensmeier and Giuseppe Pelosi
Type: Article
| 2022
Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands - Benjamin Nicholas, Alistair Bailey, Karl J. Staples, Thomas Wilkinson, Timothy Elliott and Paul Skipp
Type: Article
| 2022
Type: Article
| 2022
| Item not available on this server.
Differences in coagulation-relevant parameters: Comparing cryoprecipitate and a human fibrinogen concentrate - Ashok Roy, Sophia Stanford, Catherine Rea, Tom Cecil, Oliver Hegener, Petra Schulz, Anna Turaj, Sean Lim and Emily Arbuthnot Smith
Type: Article
| 2022
| Item not available on this server.
Type: Article
| 2022
Influence of hospital facilities on patient outcomes following cancer surgery: an international, prospective observational study - Malcolm West
Type: Article
| 2022
Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments - Jane Willoughby, Juliet Gray, Stephen Beers, Julia Moreno vicente and Jane Willoughby
Type: Article
| 2022
Body composition and chemotherapy toxicity in women with early breast cancer (CANDO-3): protocol for an observational cohort study - Stephen Wootton, Kesta Durkin, Mohammad, Adam Heetun, Sean Ewings, Richard Munday, Lesley Turner, Ellen Copson and Ramsey Cutress
Type: Article
| 2022
Limits of accuracy for parameter estimation and localization in single-molecule microscopy via sequential Monte Carlo methods - A. Marie d'Avigneau, Sumeetpal S. Singh and Raimund J. Ober
Type: Article
| 2022
Type: Article
| 2022
Dataset
Type: Dataset
| 2022
| University of Southampton
Review
Neuroblastoma: a master of disguise and a challenge to cure - Debora Calderoni, Giuseppe Barone, Martin Elliot, Deborah A. Tweedle, Ramya Ramanujachar and Juliet Gray
Type: Review
| 2022
| Item availability restricted.
Type: Review
| 2022
| Item availability restricted.
HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management - Matt Lechner, Jacklyn Liu, Liam Masterson and Tim R. Fenton
Type: Review
| 2022
| Item availability restricted.
Genomic alterations in salivary gland carcinomas: an illustrated update - Karwan A. Moutasim and Gareth J. Thomas
Type: Review
| 2022
| Item availability restricted.
Human inhibitory leukocyte Ig-like receptors: from immunotolerance to immunotherapy - Ali Roghanian and Calvin De Louche
Type: Review
| 2022
Risk-Adjusted Cancer Screening and Prevention (RiskAP): complementing screening for early disease detection by a learning screening based on risk factor - Rita K. Schmutzler, Bjorn Schmitz-Luhn, Bettina Borisch, Peter Devilee, Diana Eccles, Per Hall, Judith Balmaña, Stefania Boccia, Peter Dabrock, Günter Emons, Wolfgang Gaissmaier, Jacek Gronwald, Stefanie Houwaart, Stefan Huster, Karin Kast, Alexander Katalinic, Sabine C. Linn, Gert Matthijs, Sowmiya Moorthie, Paul Pharoah, Kerstin Rhiem, Tade Spranger, Dominique Stoppa-Lyonnet, Johannes Jozef Marten van Delden, Marc van den Bulcke and Christiane Woopen
Type: Review
| 2022