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Items where Division is "Faculties (pre 2018 reorg) > Faculty of Medicine (pre 2018 reorg) > Cancer Sciences (pre 2018 reorg)" and Year is 2017

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Number of items: 175.

The Southampton Consensus Guidelines for laparoscopic liver surgery: from indication to implementation - Mohammad Abu Hilal, Luca Aldrighetti, Ibrahim Dagher, Bjorn Edwin, Roberto Ivan Troisi, Ruslan Alikhanov, Somaiah Aroori, Giulio Belli, Marc Besselink, Javier Briceno, Brice Gayet, Mathieu D'Hondt, Mickael Lesurtel, Krishna Menon, Peter Lodge, Fernando Rotellar, Julio Santoyo, Olivier Scatton, Olivier Soubrane, Robert Sutcliffe, Ronald Van Dam, Steve White, Mark Christopher Halls, Federica Cipriani, Marcel Van der Poel, Ruben Ciria, Leonid Barkhatov, Yrene Gomez-Luque, Sira Ocana-Garcia, Andrew Cook, Joseph Buell, Pierre-Alain Clavien, Christos Dervenis, Giuseppe Fusai, David Geller, Hauke Lang, John Primrose, Mark Taylor, Thomas Van Gulik, Go Wakabayashi, Horacio Asbun and Daniel Cherqui
Type: Article | 2017

Sex-specific expression of apolipoprotein levels following replenishment of vitamin D - Nasser M. Al-Daghri, Kaiser Wani, Shaun Sabico, Spiros Garbis, George P. Chrousos, Osama E. Amer, Mohammed Ghouse Ahmed Ansari, Yousef Al-Saleh, Naji J. Aljohani, Omar S. Al-Attas and Majed S. Alokail
Type: Review | 2017 | Item availability restricted.

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus - M. Azim Ansari, Vincent Pedergnana, Camilla L.C. Ip, Andrea Magri, Annette Von Delft, David Bonsall, Nimisha Chaturvedi, Istvan Bartha, David Smith, George Nicholson, Gilean McVean, Amy Trebes, Paolo Piazza, Jacques Fellay, Graham Cooke, Graham R. Foster, Emma Hudson, John McLauchlan, Peter Simmonds, Rory Bowden, Paul Klenerman, Eleanor Barnes and Chris C.A. Spencer
Type: Article | 2017 | Item not available on this server.

Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors - Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon, Kroopa Joshi, Leila Mekkaoui, Marta H. Lesko, Enrique Miranda Rota, Rony Dahan, Andrew Georgiou, Anna Sledzinska, Assma Ben Aissa, Dafne Franz, Mariana Werner Sunderland, Yien Ning Sophia Wong, Jake Y. Henry, Tim O'Brien, David Nicol, Ben Challacombe, Stephen A. Beers, Samra Turajlic, Martin Gore, James Larkin, Charles Swanton, Kerry A Chester, Martin Pule, Jeffrey V. Ravetch, Teresa Marafioti, Karl S. Peggs and Sergio A. Quezada
Type: Article | 2017

Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain - Katharine Askew, Kaizhen Li, Adrian Olmos Alonso, Fernando Garcia-Moreno, Yajie Liang, Philippa Richardson, Thomas Tipton, Mark Chapman, Kristoffer Riecken, Sol Beccari, Amanda Sierra, Zoltan Molnar, Mark S. Cragg, Olga Garaschuk, Hugh Perry and Diego Gomez-Nicola
Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

Validation of a health-related quality of life instrument for primary ciliary dyskinesia (QOL-PCD) - Laura Behan, Margaret W. Leigh, Sharon D. Dell, Audrey Dunn Galvin, Alexandra L. Quittner and Jane S. Lucas
Type: Article | 2017

The patient's experience of primary ciliary dyskinesia: a systematic review - Laura Behan, Bruna Rubbo, Jane Lucas and Audrey Dunn Galvin
Type: Article | 2017

Type: Book Section | 2017 | Humana | Item not available on this server.

Radioimmunotherapy-augmented BEAM chemotherapy vs BEAM alone as the high-dose regimen for autologous stem cell transplantation (ASCT) in relapsed follicular lymphoma (FL): Retrospective study of the EBMT Lymphoma Working Party - L. Bento, A. Boumendil, H. Finel, S. Le Gouill, S. Amorim, H. Monjanel, R Bouabdallah, J.O. Bay, E. Nicolas-Virelizier, G. McQuaker, G. Rossi, R. Johnson, A. Huynh, P. Ceballos, A. Rambaldi, E. Bachy, R. Malladi, K. Orchard, D. Pohlreich, H. Tilly, F. Bonifazi, X. Poiré, F. Guilhot, A. Haenel, C. Crawley, B. Metzner, J. Gribben, N.H. Russell, G. Damaj, K. Thomson, P. Dreger and S. Montoto
Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

Profiling the microRNA payload of exosomes derived from ex vivo primary colorectal fibroblasts - Rahul Bhome, Rebecca Goh, Karen Pickard, Massimiliano Mellone, A. Emre Sayan and Alex Mirnezami
Type: Book Section | 2017 | Humana | Item not available on this server.

Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression - Rahul Bhome, Rebecca W Goh, Marc D. Bullock, Nir Pillar, Stephen M. Thirdborough, Massimiliano Mellone, Reza Mirnezami, Dieter Galea, Kirill Veselkov, Quan Gu, Timothy J. Underwood, John N. Primrose, Olivier De Wever, Noam Shomron, A. Emre Sayan and Alex H. Mirnezami
Type: Article | 2017

The dual Syk/JAK inhibitor cerdulatinib antagonizes B-cell receptor and microenvironmental signaling in chronic lymphocytic leukemia - Matthew D. Blunt, Stefan Koehrer, Rachel C. Dobson, Marta Larrayoz, Sarah Wilmore, Alice Hayman, Jack Parnell, Lindsay D. Smith, Andrew Davies, Peter W.M. Johnson, Pamela B. Conley, Anjali Pandey, Jonathan C. Strefford, Freda K. Stevenson, Graham Packham, Francesco Forconi, Greg P Coffey, Jan A. Burger and Andrew J. Steele
Type: Article | 2017

Fluorinated tranylcypromine analogues as inhibitors of lysine-specific demethylase 1 (LSD1, KDM1A) - Maria Teresa Borrello, Benjamin Schinor, Katharina Bartels, Hanae Benelkebir, Sara Pereira, Wafa T. Al-Jamal, Leon Douglas, Patrick J. Duriez, Graham Packham, Günter Haufe and Anusha Ganesan
Type: Article | 2017

Radical cystectomy or bladder preservation with radiochemotherapy in elderly patients with muscle-invasive bladder cancer: retrospective international study of cancers of the urothelial tract (RISC) investigators - Jihane Boustani, Aurélie Bertaut, Matthew D. Galsky, Jonathan E. Rosenberg, Joaquim Bellmunt, Thomas Powles, Federica Recine, Lauren C. Harshman, Simon Chowdhury, Guenter Niegisch, Evan Y. Yu, Sumanta K. Pal, Ugo De Giorgi, Simon J. Crabb, Matthieu Caubet, Loïc Balssa, Matthew I. Milowsky, Sylvain Ladoire and Gilles Créhange
Type: Article | 2017

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology - Patience Brace, Liku B. Tezera, Magdalena K. Bielecka, Toby Mellows, Diana Garay, Shuye Tian, Lucinda Rand, Justin Green, Sanjay Jogai, Andrew Steele, Timothy M. Millar, Tilman Sanchez-Elsner, Jon S. Friedland, Christopher G. Proud and Paul T. Elkington
Type: Article | 2017

Hiatal hernia after esophagectomy for cancer - Hylke J.F. Brenkman, Kevin Parry, Fergus Noble, Richard van Hillegersberg, Donna Sharland, Lucas Goense, Jamie Kelly, James P. Byrne, Timothy J. Underwood and Jelle P. Ruurda
Type: Article | 2017 | Item not available on this server.

Hiatal hernia following esophagectomy for cancer - Hylke JF Brenkman, Kevin Parry, FERGUS NOBLE, Richard van Hillegersberg, Donna Sharland, Lucas Goense, Jamie Kelly, James P Byrne, Timothy Underwood and Jelle P Ruurda
Type: Article | 2017

Microwave therapy for cutaneous human papilloma virus infection - Ian Bristow, Wen Chean Lim, Alvin Lee, Daniel Holbrook, Natalia Savelyeva, Peter Thomson, Christopher Webb, Marta Polak and Michael Ardern-Jones
Type: Article | 2017

Response-adapted therapy in Hodgkin lymphoma - Jack Broadfoot and Peter W.M. Johnson
Type: Article | 2017 | Item availability restricted.

Physical activity and quality of life in cancer survivors: A meta-synthesis of qualitative research - Shaunna M. Burke, Amanda Wurz, Andrew Bradshaw, Stephanie Saunders, Malcolm A. West and Jennifer Brunet
Type: Article | 2017

An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation - Francisco J. Candido do Reis, Gordon C. Wishart, Ed M. Dicks, David Greenberg, Jem Rashbass, Marjanka K. Schmidt, Alexandra J. van den Broekma, Ian O. Ellis, Andrew Green, Emad Rakha, Tom Maishman, Diana M. Eccles and Paul D.P. Pharoah
Type: Article | 2017

Recontacting in clinical practice: an investigation of the views of healthcare professionals and clinical scientists in the United Kingdom - Daniele Carrieri, Sandi Dheensa, Shane Doheny, Angus J. Clarke, Peter D. Turnpenny, Anneke Lucassen and Susan E. Kelly
Type: Article | 2017

Recontacting in clinical genetics and genomic medicine? We need to talk about it. - Daniele Carrieri, Sandi Dheensa, Shane Doheny, Angus J. Clarke, Peter D. Turnpenny, Anneke M. Lucassen and Susan E. Kelly
Type: Letter | 2017 | Item not available on this server.

PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis - Matthew Carter, Kerry Cox, Stuart Blakemore, Anna Turaj, Robert Oldham, Lekh Dahal, Stacey Tannheimer, Francesco Forconi, Graham Packham and Mark Cragg
Type: Article | 2017

Training improves the interobserver agreement of the expert positron emission tomography review panel in primary mediastinal B-cell lymphoma: interim analysis in the ongoing International Extranodal Lymphoma Study Group-37 study - Luca Ceriani, Sally Barrington, Alberto Biggi, Bogdan Malkowski, Ur Metser, Annibale Versari, Maurizio Martelli, Andrew Davies, Peter W Johnson, Emanuele Zucca and Stéphane Chauvie
Type: Review | 2017 | Item availability restricted.

Prognostic models for primary mediastinal (thymic) B-cell lymphoma derived from 18-FDG PET/CT quantitative parameters in the International Extranodal Lymphoma Study Group (IELSG) 26 study - Luca Ceriani, Maurizio Martelli, Annarita Conconi, Pier L Zinzani, Andrés J M Ferreri, Barbara Botto, Caterina Stelitano, Manuel Gotti, Maria G Cabras, Luigi Rigacci, Luca Giovanella, Emanuele Zucca and Peter W.M. Johnson
Type: Article | 2017 | Item not available on this server.

Positron emission tomography/computed tomography assessment after immunochemotherapy and irradiation using the lugano classification criteria in the IELSG-26 study of primary mediastinal B-cell lymphoma - Luca Ceriani, Maurizio Martelli, Maria K Gospodarowicz, Umberto Ricardi, Andrés J M Ferreri, Annalisa Chiappella, Caterina Stelitano, Monica Balzarotti, Maria E Cabrera, David Cunningham, Attilio Guarini, Pier Luigi Zinzani, Luca Giovanella, Peter W M Johnson and Emanuele Zucca
Type: Article | 2017 | Item not available on this server.

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains - Andrew Chancellor, Anna Tocheva, Christopher Cave-Ayland, Liku Bekele Tezera, Andrew White, Juma'a Al Dulayymi, John Bridgeman, Ivo Tews, Susan Wilson, Nikolai Lissin, Marc Tebruegge, Benjamin Marshall, Sally Sharpe, Timothy Elliott, Chris-Kriton Skylaris, Jonathan W. Essex, Mark Baird, Stephan D. Gadola, Paul Elkington and Salah Mansour
Type: Article | 2017

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection - Andrew Chancellor, Andrew White, Anna S. Tocheva, Joe R. Fenn, Mike Dennis, Liku Tezera, Akul Singhania, Timothy Elliott, Marc Tebruegge, Paul Elkington, Stephan D. Gadola, Sally Sharpe and Salah Mansour
Type: Article | 2017

Evaluating the effect of immune cells on the outcome of patients with mesothelioma - Serena J. Chee, Maria Lopez, Toby Mellows, Karwan A. Moutasim, Scott Harris, James, Ian Clarke, Pandurangan Vijayanand, Gareth J. Thomas and Christian H. Ottensmeier
Type: Article | 2017

Antibody distance from the cell membrane regulates antibody effector mechanisms - Kirstie L.S. Cleary, H.T. Claude Chan, Sonya James, Martin J. Glennie and Mark S. Cragg
Type: Article | 2017 | Item availability restricted.

The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis - Franco Conforti, Elizabeth R. Davies, Claire J. Calderwood, Thomas H. Thatcher, Mark G. Jones, David E. Smart, Sumeet Mahajan, Aiman Alzetani, Tom Havelock, Toby M. Maher, Philip L. Molyneaux, Andrew J. Thorley, Teresa D. Tetley, Jane A. Warner, Graham Packham, A. Ganesan, Paul J. Skipp, Benjamin J. Marshall, Luca Richeldi, Patricia J. Sime, Katherine M.A. O'Reilly and Donna E. Davies
Type: Article | 2017

Primary clear cell microcystic adenoma of the sinonasal cavity: pathological or fortuitous association? - Rosalin Cooper, Hannah Markham, Jeffery Theaker, Adrian Bateman, David Bunyan, Matthew Sommerlad, Gillian Crawford and Diana Eccles
Type: Article | 2017

ProCAID: a phase I clinical trial to combine the AKT inhibitor AZD5363 with docetaxel and prednisolone chemotherapy for metastatic castration resistant prostate cancer - Simon J. Crabb, Alison J. Birtle, Karen Martin, Nichola Downs, Ian Ratcliffe, Thomas Maishman, Mary Ellis, Gareth Griffiths, Stuart Thompson, Lidia Ksiazek, Vincent Khoo and Robert J Jones
Type: Article | 2017

COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-loss - Simon J. Crabb, Karen Martin, Julia Abab, Ian Ratcliffe, Roger Thornton, Ben Lineton, Mary Ellis, Ronald Moody, Louise Stanton, Angeliki Galanopoulou, Tom Maishman, Thomas Geldart, Mike Bayne, Joe Davies, Carolynn Lamb, Sanjay Popat, Johnathan K. Joffe, Chris Nutting, John Chester, Andrew Hartley, Gareth Thomas, Christian Ottensmeier, Robert Huddart and Emma King
Type: Article | 2017

Development of a T cell receptor mimic antibody against wild-type p53 for cancer immunotherapy - Mark Cragg, Demin Li, Caroline Bentley, Amanda Anderson, Sarah Wiblin, Kirstie Cleary, Sofia Koustoulidou, Tasneem Hassanali, Jenna Yates, Jenny Grieg and Iva Trenevska
Type: Article | 2017

anti-FcγRIIB (CD32) antibodies differentially modulate murine FVIII-specific recall response in vitro - Mark Cragg, Nadine Vollack, Julia Friese, Sabine Bergmann, Andreas Tiede and Sonja Werwitzke
Type: Article | 2017

Prognostic significance and correlation to gene expression profile of EZH2 mutations in diffuse large B‐cell lymphoma (DLBL) in 2 large prospective studies - T.E. Cummin, S. Araf, M. Du, S. Barrans, M.A. Bentley, A. Clipson, M. Wang, S. Ahmed, T. Rahim, C. Shah, D. Hamid, J. Dhondt, T. Maishman, N. Vaughan-Spickers, C. Pocock, A. Forbes, A. O'Callaghan, D.R. Westhead, G.O. Griffiths, J. Fitzgibbon, R.M. Tooze, M.A. Care, C.H. Burton, A.J. Davies and P.W. Johnson
Type: Meeting abstract | 2017 | Item not available on this server.

A phase 2/3 multicenter, randomized, open-label study to compare the efficacy and safety of Lenalidomide versus investigator's choice in patients with relapsed or refractory diffuse large B-Cell lymphoma - Myron S. Czuczman, Marek Trněný, Andrew Davies, Simon Rule, Kim M. Linton, Nina Wagner-Johnston, Randy D. Gascoyne, Graham W Slack, Pierre Brousset, David A. Eberhard, Francisco J. Hernandez-Ilizaliturri, Gilles Salles, Thomas E. Witzig, Pier Luigi Zinzani, George W. Wright, Louis M. Staudt, Yandan Yang, P. Mickey Williams, Chih-Jian Lih, Jacqueline Russo, Anjan Thakurta, Patrick Hagner, Pierre Fustier, Dale Song and Ian D. Lewis
Type: Article | 2017 | Item not available on this server.

STING activation reverses lymphoma-mediated resistance to antibody immunotherapy - Lekh N Dahal, Lang Dou, Khiyam Hussain, Rena Liu, Alexander Earley, Kerry L Cox, Salome Murinello, Ian Tracy, Francesco Forconi, Andrew J Steele, Patrick Duriez, Diego Gomez-Nicola, Jessica L Teeling, Martin J Glennie, Mark S Cragg and Stephen A Beers
Type: Article | 2017

Recontacting in clinical practice: the views and expectations of patients in the United Kingdom - Carrieri Daniele, Sandeep Dheensa, Shane Doheny, Angus Clarke, Peter Turnpenny, Anneke Lucassen and Susan Kelly
Type: Article | 2017

Differential efficacy of bortezomib in subtypes of diffuse large B‐cell lymphoma (dlbl): a prospective randomised study stratified by transcriptome profiling: remodl‐B - A.J. Davies, S. Barrans, T. Maishman, T.E. Cummin, M. Bentley, C. Mamot, U. Novak, J. Caddy, D. Hamid, S.H. Kazmi-Stokes, A. Mcmillan, P.A. Fields, C. Pocock, A. Kruger, G. Collins, C. Sha, A. Clipson, M. Wang, R.M. Tooze, M.A. Care, G.O. Griffiths, M. Du, D.R. Westhead, C. Burton, A. Jack and P.W. Johnson
Type: Meeting abstract | 2017 | Item not available on this server.

Type: Review | 2017 | Item not available on this server.

Subcutaneous Rituximab for the treatment of B-cell hematologic malignancies: A review of the scientific rationale and clinical development - Andrew Davies, Claude Berge, Axel Boehnke, Anjum Dadabhoy, Pieternella Lugtenburg, Simon Rule, Mathias Rummel, Christine McIntyre, Rodney Smith and Xavier Badoux
Type: Review | 2017

Efficacy and safety of subcutaneous rituximab versus intravenous rituximab for first-line treatment of follicular lymphoma (SABRINA): a randomised, open-label, phase 3 trial - Andrew Davies, Francesco Merli, Biljana Mihaljević, Santiago Mercadal, Noppadol Siritanaratkul, Philippe Solal-Céligny, Axel Boehnke, Claude Berge, Magali Genevray, Artem Zharkov, Mark Dixon, Michael Brewster, Martin Barrett and David MacDonald
Type: Article | 2017 | Item not available on this server.

A study of splicing mutations in disorders of sex development - Flavia Leme De Calais, Lindsay D. Smith, Michela Raponi, Andréa Trevas Maciel-guerra, Gil Guerra-junior, Maricilda Palandi De Mello and Diana Baralle
Type: Article | 2017

How do clinical genetics consent forms address the familial approach to confidentiality and incidental findings? A mixed-methods study - Sandeep Dheensa, Gillian Susann Crawford, Claire G. Salter, Michael Parker, Angela Fenwick and Anneke Lucassen
Type: Article | 2017

Type: Article | 2017

A 'joint venture' model of recontacting in clinical genomics: challenges for responsible implementation - Sandi Dheensa, Daniele Carrieri, Susan Kelly, Angus Clarke, Shane Doheny, Peter Turnpenny and Anneke Lucassen
Type: Article | 2017

Type: Article | 2017

Beyond individualism: Is there a place for relational autonomy in clinical practice and research? - Edward S. Dove, Susan E. Kelly, Federica Lucivero, Mavis Machirori, Sandeep Dheensa and Barbara Prainsack
Type: Article | 2017

IL-10 production by CLL cells is enhanced in the anergic IGHV mutated subset and associates with reduced DNA methylation of the IL10 locus - S. Drennan, A. D'Avola, Y. Gao, C. Weigel, E. Chrysostomou, A.J. Steele, T. Zenz, C. Plass, P.W. Johnson, A.O. Williams, G. Packham, F.K. Stevenson, C.C. Oakes and F. Forconi
Type: Article | 2017

Body mass index and breast cancer survival: A Mendelian randomisation analysis - Diana Eccles, Qi Guo, Stephen Burgess and Constance Turman
Type: Article | 2017

Association analysis identifies 65 new breast cancer risk loci and predicts target genes - Diana Eccles, Kyriaki Michailidou, Sara Lindstrom and Joe Dennis
Type: Article | 2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer - Diana Eccles, Catherine M. Phelan, Karoline B. Kuchenbaecker, Jonathan P. Tyrer, Siddhartha Kar, Kate Lawrenson, Stacey J. Winham, Joe Dennis, Ailith Pirie, Marjorie J. Riggan, Ganna Chornokur, Madalene A. Earp, Paulo C. Lyra Jr., Janet M. Lee, Simon Coetzee, Jonathan Beesley, Lesley McGuffog, Penny Soucy, Ed Dicks, Andrew Lee, Daniel Barrowdale, Julie Lecarpentier, Leslie Goska, Cora M. Aalfs, Katja K.H. Aben, Marcia Adams, Julian Adlard, Irene L. Andrulis, Hoda Anton-Culver and Natalia Antonenkova
Type: Article | 2017 | Item availability restricted.

Secondary malignant neoplasms, progression-free survival and overall survival in patients treated for Hodgkin lymphoma: a systematic review and meta-analysis of randomized clinical trials - Dennis A. Eichenauer, Ingrid Becker, Ina Monsef, Nicholas Chadwick, Vitaliana de Sanctis, Massimo Federico, Catherine Fortpied, Alessandro M. Gianni, Michel Henry-Amar, Peter Hoskins, Peter Johnson, Stefano Luminari, Monica Bellei, Alessandro Pulsoni, Matthew R. Sydes, Pinuccia Valagussa, Simonetta Viviani, Andreas Engert and Jeremy Franklin
Type: Article | 2017

Survival at the brink: Chromatin autophagy of tumor cells in response to genotoxic challenge - Jekaterina Erenpreisa, Kristine Salmina, Alexander Belyayev, Inna Inashkina and Mark S. Cragg
Type: Book Section | 2017 | Academic Press | Item not available on this server.

HIV-2 infection is associated with preserved GALT homeostasis and epithelial integrity despite ongoing mucosal viral replication - S.M. Fernandes, A.R. Pires, P. Matoso, C. Ferreira, H. Nunes-Cabaço, L. Correia, E. Valadas, J. Poças, A.P. Pacheco, H. Veiga-Fernandes, R.B. Foxall and A.E. Sousa
Type: Article | 2017 | Item not available on this server.

Whole-brain radiotherapy or autologous stem-cell transplantation as consolidation strategies after high-dose methotrexate-based chemoimmunotherapy in patients with primary CNS lymphoma: results of the second randomisation of the International Extranodal Lymphoma Study Group-32 phase 2 trial - Andrés J.M. Ferreri, Kate Cwynarski, Elisa Pulczynski, Christopher P Fox, Elisabeth Schorb, Paul La Rosée, Mascha Binder, Alberto Fabbri, Valter Torri, Eleonora Minacapelli, Monica Falautano, Fiorella Ilariucci, Achille Ambrosetti, Alexander Roth, Claire Hemmaway, Peter Johnson, Kim M. Linton, Tobias Pukrop, Jette Sønderskov Gørløv, Monica Balzarotti, Georg Hess, Ulrich Keller, Stephan Stilgenbauer, Jens Panse, Alessandra Tucci, Lorella Orsucci, Francesco Pisani, Alessandro Levis, Stefan W Krause, Hans J. Schmoll, Bernd Hertenstein, Mathias Rummel, Jeffery Smith, Michael Pfreundschuh, Giuseppina Cabras, Francesco Angrilli, Maurilio Ponzoni, Martina Deckert, Letterio S. Politi, Jürgen Finke, Michele Reni, Franco Cavalli, Emanuele Zucca and Gerald Illerhaus
Type: Article | 2017

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation - Antonio Galleu, Yanira Riffo-Vasquez, Cristina Trento, Cara Lomas, Luigi Dolcetti, Tik Shing Cheung, Malte von Bonin, Laura Barbieri, Krishma Halai, Sophie Ward, Ling Weng, Ronjon Chakraverty, Giovanna Lombardi, Fiona M. Watt, Kim Orchard, David I Marks, Jane Apperley, Martin Bornhauser, Henning Walczak, Clare Bennett and Francesco Dazzi
Type: Article | 2017

Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer - Anusha-Preethi Ganesan, James Clarke, Oliver Wood, Eva M Garrido-Martin, Serena J. Chee, Toby Mellows, Daniela Samaniego-Castruita, Divya Singh, Grégory Seumois, Aiman Alzetani, Edwin Woo, Peter S Friedmann, Emma V King, Gareth J Thomas, Tilman Sanchez-Elsner, Pandurangan Vijayanand and Christian H Ottensmeier
Type: Article | 2017

No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs - Julia M. Geissler, David J. Burn, Clare Harris, Karen E. Morrison, Robert Walker, Marcel Romanos, Manfred Gerlach, Daniela Berg and Claudia Schulte
Type: Article | 2017 | Item not available on this server.

Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment - P. Ghia, B. Nadel, B. Sander, K. Stamatopoulos and F.K. Stevenson
Type: Article | 2017 | Item not available on this server.

Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer - Chloe Grimmett, Karen Pickett, Jonathan Shepherd, Karen Welch, Alejandra Recio Saucedo, Elke Streit, Helen Seers, Anne Armstrong, Ramsey I. Cutress, D. Gareth Evans, Ellen Copson, Bettina Meiser, Diana Eccles and Claire Foster
Type: Article | 2017

Assessment of neuronal autoantibodies in patients with Small Cell Lung Cancer treated with chemotherapy with or without Ipilimumab - M. Hardy-Werbin, O. Arpi, A. Taus, P. Rocha, D. Joseph-Pietras, L. Nolan, S. Danson, R. Griffiths, M. Lopez-Botet, A. Rovira, J. Albanell, C. Ottensmeier and E. Arriola
Type: Article | 2017

Type: Article | 2017

Type: Article | 2017

Qualitative assessment of the symptoms and impact of Pancreatic Exocrine Insufficiency (PEI) to inform the development of a Patient-Reported Outcome (PRO) instrument - Colin D. Johnson, Rob Arbuckle, Nicola Bonner, Gary Connett, Enrique Dominguez-Munoz, Philippe Levy, Doris Staab, Nicola Williamson and Markus M. Lerch
Type: Article | 2017

Integrated cellular and plasma proteomics of contrasting B-cell cancers reveals common, unique and systemic signatures - Harvey Johnston, Matthew Carter, Kerry Cox, Melanie Dunscombe, Antigoni Manousopoulou, Paul Townsend, Spiros Garbis and Mark Cragg
Type: Article | 2017

Randomized phase II study investigating Pazopanib versus weekly Paclitaxel in relapsed or progressive urothelial cancer - Robert J. Jones, Syed A. Hussain, Andrew S. Protheroe, Alison Birtle, Prabir Chakraborti, Robert A. Huddart, Satinder Jagdev, Amit Bahl, Andrew Stockdale, Santhanam Sundar, Simon J. Crabb, Judith Dixon-Hughes, Laura Alexander, Anna Morris, Caroline Kelly, Jon Stobo, James Paul and Thomas Powles
Type: Article | 2017

Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women - Latha Kadalayil, Sofia Khan, Heli Nevanlinna, Peter Fasching, Fergus Couch, John Hopper, Jianjun Liu, Thomas Maishman, Lorraine Durcan, Sue Gerty, Carl Blomqvist, Brigitte Rack, Wolfgang Janni, Andrew Collins, Diana Eccles and William Tapper
Type: Article | 2017

Effect of β-blockade on lung function, exercise performance and dynamic hyperinflation in people with arterial vascular disease with and without COPD - Angela Key, Matthew Parry, Malcolm West, Rebecca Asher, Sandy Jack, Nicholas Duffy, Francesco Torella and Paul Walker
Type: Article | 2017

Chronic lymphocytic leukaemia - Thomas J Kipps, Freda K Stevenson, Catherine J Wu, Carlo M Croce, Graham Packham, William G Wierda, Susan O'Brien, John Gribben and Kanti Rai
Type: Article | 2017 | Item not available on this server.

Chronic lymphocytic leukaemia: Correction - Thomas J. Kipps, Freda K. Stevenson, Catherine J. Wu, Carlo M. Croce, Graham Packham, William G. Wierda, Susan O'brien, John Gribben and Kanti Rai
Type: Article | 2017 | Item not available on this server.

Lamin B1 regulates somatic mutation and progression of B cell malignancies - Tetyana Klymenko, Johannes Bloehdorn, Jasmin Bahlo, Sandra Robrecht, Andrew Clear, Kerry Cox, Sven Estenfelder, Jun Wang, Jennifer Edelmann, Jonathan Strefford, Tomasz K. Wojdacz, Kirsten Fischer, Michael Hallek, Stephan Stilgenbauer, Mark Cragg, John Gribben and Andrejs Braun
Type: Article | 2017

Type: Article | 2017

Outcome of elderly patients with diffuse large B-cell lymphoma treated with R-CHOP: results from the UK NCRI R-CHOP14v21 trial with combined analysis of molecular characteristics with the DSHNHL RICOVER-60 trial - A. Kühnl, D. Cunningham, N. Counsell, E.A. Hawkes, W. Qian, P. Smith, N. Chadwick, A. Lawrie, P. Mouncey, A. Jack, C. Pocock, K.M. Ardeshna, J. Radford, A. McMillan, J. Davies, D. Turner, A. Kruger, P. Johnson, J. Gambell, A. Rosenwald, G. Ott, H. Horn, M. Ziepert, M. Pfreundschuh and D. Linch
Type: Article | 2017

Non-coding NOTCH1 mutations in chronic lymphocytic leukemia; their clinical impact in the UK CLL4 trial - M. Larrayoz, M.J.J. Rose-Zerilli, L. Kadalayil, H. Parker, S. Blakemore, J. Forster, Z. Davis, A.J. Steele, A. Collins, M. Else, D. Catovsky, D.G. Oscier and J.C. Strefford
Type: Article | 2017

Radiopathological features predictive of involved margins in ductal carcinoma in situ - D.M. Layfield, H. See, M. Stahnke, L Hayward, R. Cutress and Rs Oeppen
Type: Article | 2017 | Item availability restricted.

ANRIL promoter DNA methylation: a perinatal marker for later adposity - Karen Lillycrop, Robert Murray, Clara Cheong, Ai Ling Teh, Rebecca Clarke-Harris, Sheila Barton, Paula Costello, Emma Garratt, Eloise Cook, Philip Titcombe, Bhuvaneshwari Shunmuganathan, Samantha J. Liew, Yong-Cai Chua, Xinyi Lin, Yonghui Wu, Graham Burdge, Cyrus Cooper, Hazel Inskip, Neerja Karmani, James C. Hopkins, Caroline E. Childs, Carolina Paras Chavez, Philip C. Calder, Fabian Yap, Yung Lee, Yap-Seng Chong, Philip E. Melton, Lawrie Beilin, Rae-Chi Huang, Peter D. Gluckman, Nicholas Harvey, Mark A. Hanson, Joanna D. Holbrook and Keith M. Godfrey
Type: Article | 2017

Type: Article | 2017

European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia - Jane Lucas, Angelo Barbato, Samuel A. Collins, Myrofora Goutaki, Laura Behan, Daan Caudri, Sharon Dell, Ernst Eber, Estelle Escudier, Robert A. Hurst, Claire Hogg, Mark Jorissen, Philipp Latzin, Marie Legendre, Margaret W. Leigh, Fabio Midulla, Kim G. Nielsen, Heymut Omran, Jean-Francois Papon, Petr Pohunek, Beatrice Redfern, David Rigau, Bernhard Rindlisbacher, Francesca Santamaria, Amelia Shoemark, Deborah Snijders, Thomy Tonia, Andrea Titieni, Woolf T. Walker, Claudius Werner, Andrew Bush and Claudia E. Kuehni
Type: Article | 2017

Ethical issues in precision oncology/cancer genetics - Anneke Lucassen and Angela Fenwick
Type: Book Section | 2017 | Clinical Publishing | Item availability restricted.

Type: Article | 2017 | Item not available on this server.

Chapter 16. Ethics and the social contract for genomics in the NHS - Anneke Lucassen, Jonathan Montgomery and Michael Parker
Type: Book Section | 2017 | Department of Health | Item availability restricted.

Prostate artery embolization: a new, minimally invasive treatment for lower urinary tract symptoms secondary to prostate enlargement - Drew Maclean, Ben Maher, Sachin Modi, Mark Harris, Jonathan Dyer, Bhaskar Somani, Nigel Hacking and Timothy Bryant
Type: Article | 2017 | Item not available on this server.

A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent - David Mant, Alastair Gray, Sian Pugh, Helen Campbell, Stephen George, Alice Fuller, Bethany Shinkins, Andrea Corkhill, Jane Mellor, Elizabeth Dixon, Louisa Little, Rafael Perera-Salazar and John Primrose
Type: Article | 2017 | Item not available on this server.

Obinutuzumab for the first-line treatment of follicular lymphoma - Robert Marcus, Andrew Davies, Kiyoshi Ando, Wolfram Klapper, Stephen Opat, Carolyn Owen, Elizabeth Phillips, Randeep Sangha, Rudolf Schlag, John F Seymour, William Townsend, Marek Trněný, Michael Wenger, Günter Fingerle-Rowson, Kaspar Rufibach, Tom Moore, Michael Herold and Wolfgang Hiddemann
Type: Article | 2017 | Item not available on this server.

Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes - Danielle Marjoram, Yoelys Cruz-leal, Lidice Bernardo, Ngoc Phuong Lan Le, Max Crispin, Xiaojie Yu, Makoto Uchikawa and Alan H. Lazarus
Type: Letter | 2017

Therapeutic antibodies: What have we learnt from targeting CD20 and where are we going? - Michael J.E. Marshall, Richard J. Stopforth and Mark S. Cragg
Type: Article | 2017

Primary mediastinal large B-cell lymphoma - Maurizio Martelli, Andrés Ferreri, Alice Di Rocco, Michela Ansuinelli and Peter W.M. Johnson
Type: Article | 2017 | Item not available on this server.

Deep sequencing reveals the mitochondrial DNA variation landscapes of breast-to-brain metastasis blood samples - Rhiannon E. McGeehan, Lewis A. Cockram, D. Timothy J. Littlewood, Kathleen Keatley, Diana M. Eccles and Qian An
Type: Article | 2017

Identification of ten variants associated with risk of estrogen receptor negative breast cancer - Roger L. Milne, Karoline B. Kuchenbaeker, Kyriaki Michailidou, Diana Eccles, Lorraine Durcan and Thomas Maishman
Type: Article | 2017

The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium - Setareh Moghadasi, Huong D. Meeks, Maaike P.G. Vreeswijk, Linda Am Janssen, Åke Borg, Hans Ehrencrona, Ylva Paulsson-Karlsson, Barbara Wappenschmidt, Christoph Engel, Andrea Gehrig, Norbert Arnold, Thomas Van Overeem Hansen, Mads Thomassen, Uffe Birk Jensen, Torben A. Kruse, Bent Ejlertsen, Anne-Marie Gerdes, Inge Søkilde Pedersen, Sandrine M. Caputo, Fergus Couch, Emily J. Hallberg, Ans M.W. van den Ouweland, Margriet J. Collée, Erik Teugels, Muriel A. Adank, Rob B. van der Luijt, Arjen R. Mensenkamp, Jan C. Oosterwijk, Marinus J. Blok, Nicolas Janin, Kathleen B.M. Claes, Kathy Tucker, Valeria Viassolo, Amanda Ewart Toland, Diana E. Eccles, Peter Devilee, Christie J. Van Asperen, Amanda B. Spurdle, David E. Goldgar and Encarna Gómez García
Type: Article | 2017 | Item availability restricted.

Epidermal growth factor receptor family inhibition identifies P38 Mitogen-activated protein kinase as a potential therapeutic target in bladder cancer - Regina Mora Vidal, Sergio Regufe da Mota, Annette Hayden, Hannah Markham, James Douglas, Graham Packham and Simon J. Crabb
Type: Article | 2017

NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma - Somnath Mukherjee, Christopher Nicholas Hurt, Sarah Gwynne, David Sebag-Montefiore, Ganesh Radhakrishna, Simon Gollins, Maria Hawkins, Heike I. Grabsch, Gareth Jones, Stephen Falk, Ricky Sharma, Andrew Bateman, Rajarshi Roy, Ruby Ray, Jo Canham, Gareth Griffiths, Tim Maughan and Tom Crosby
Type: Article | 2017

Variation in the provision and practice of implant-based breast reconstruction in the UK: results from the iBRA national practice questionnaire - Senthurun Mylvaganam, Elizabeth Conroy, Paula R Williamson, Nicola L P Barnes, Ramsey I Cutress, Matthew D Gardiner, Abhilash Jain, Joanna M Skillman, Steven Thrush, Lisa J Whisker, Jane M Blazeby, Shelley Potter and Christopher Holcombe
Type: Article | 2017

Lack of effectiveness of postchemotherapy lymphadenectomy in bladder cancer patients with clinical evidence of metastatic pelvic or retroperitoneal lymph nodes only: A propensity score-based analysis - Andrea Necchi, Luigi Mariani, Salvatore Lo Vullo, Evan Y. Yu, Michael E. Woods, Yu Ning Wong, Lauren C. Harshman, Ajjaj Alva, Cora N. Sternberg, Aristotelis Bamias, Petros Grivas, Vadim S. Koshkin, Florian Roghmann, Jakub Dobruch, Bernie J. Eigl, Lucia Nappi, Matthew I. Milowsky, Guenter Niegisch, Sumanta K. Pal, Ugo De Giorgi, Federica Recine, Ulka Vaishampayan, Dominik D. Berthold, Daniel W. Bowles, Jack Baniel, Christine Theodore, Sylvain Ladoire, Sandy Srinivas, Neeraj Agarwal, Simon Crabb, Srikala Sridhar, Ali Reza Golshayan, Carsten Ohlmann, Evanguelos Xylinas, Thomas Powles, Johnathan E. Rosenberg, Joaquim Bellmunt, Bas van Rhijn, Matthew D. Galsky and Kees Hendricksen
Type: Article | 2017

Bone metastases as the only metastatic site in patients with urothelial carcinoma: Focus on a special patient population - Andrea Necchi, Gregory R. Pond, Sumanta K. Pal, Neeraj Agarwal, Daniel W. Bowles, Elizabeth R. Plimack, Evan Y. Yu, Sylvain Ladoire, Jack Baniel, Simon Crabb, Gunter Niegisch, Sandy Srinivas, Dominik R. Berthold, Jonathan E. Rosenberg, Thomas Powles, Aristotelis Bamias, Lauren C. Harshman, Joaquim Bellmunt and Matthew D. Galsky
Type: Article | 2017

Nomogram-based prediction of overall survival in patients with metastatic urothelial carcinoma receiving first-line platinum-based chemotherapy: retrospective international study of invasive/advanced cancer of the urothelium (RISC) - Andrea Necchi, Guru Sonpavde, Salvatore Lo Vullo, Daniele Giardiello, Aristotelis Bamias, Simon J. Crabb, Lauren C. Harshman, Joaquim Bellmunt, Ugo De Giorgi, Cora N. Sternberg, Linda Cerbone, Sylvain Ladoire, Yu-Ning Wong, Evan Y. Yu, Simon Chowdhury, Gunter Niegisch, Sandy Srinivas, Ulka N. Vaishampayan, Sumanta K. Pal, Neeraj Agarwal, Ajjai Alva, Jack Baniel, Ali-Reza Golshayan, Rafael Morales-Barrera, Daniel W. Bowles, Matthew I. Milowsky, Christine Theodore, Dominik R. Berthold, Gedske Daugaard, Srikala S. Sridhar, Thomas Powles, Jonathan E. Rosenberg, Matthew D. Galsky and Luigi Mariani
Type: Article | 2017

Susceptibility to influenza virus infection of bronchial biopsies in asthma - Ben Nicholas, Sarah Dudley, Kamran Tariq, Peter Howarth, Kerry Lunn, Sarah Pink, Peter J. Sterk, Ian M. Adcock, Phillip Monk and Ratko Djukanovic
Type: Letter | 2017 | Item not available on this server.

A multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma - Fergus Noble, Megan Lloyd, Richard Turkington, Ewen Griffiths, Maria O'Donovan, Robert O'Neill, Stuart Mercer, Simon Parsons, Rebecca Fitzgerald and Timothy Underwood
Type: Article | 2017

A comparative analysis of whole genome sequencing of oesophageal adenocarcinoma pre- and post-chemotherapy - Ayesha Noorani, Jan Bornschein, Andy G. Lynch, Maria Secrier, Achilleas Achilleos, Matthew Eldridge, Lawrence Bower, Jamie M.J. Weaver, Jason Crawte, Chin-Ann Ong, Nicholas Shannon, Shona MacRae, Nicola Grehan, Barbara Nutzinger, Maria O'Donovan, Richard Hardwick, Simon Tavaré, Rebecca C Fitzgerald, Rachael Fels Elliott, Paul A W Edwards, Xiaodun Li, Hamza Chettouh, Gianmarco Contini, Eleanor Gregson, Sebastian Zeki, Laura Smith, Zarah Abdullahi, Rachel de la Rue, Ahmad Miremadi, Shalini Malhotra, Mike L Smith, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Richard Turkington, Stephen J Hayes, Yeng Ang, Shaun R Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J E Skipworth, Ted R Hupp, J Robert O'Neill, Olga Tucker, Timothy J Underwood and Fergus Noble
Type: Article | 2017

Identification of a functionally significant tri-allelic genotype in the Tyrosinase gene (TYR) causing hypomorphic oculocutaneous albinism (OCA1B) - Chelsea S. Norman, Luke O'Gorman, Jane Gibson, Reuben J. Pengelly, Diana Baralle, J. Arjuna Ratnayaka, Helen Griffiths, Matthew Rose-Zerilli, Megan Ranger, David Bunyan, Helena Lee, Rhiannon Page, Tutte Newall, Fatima Shawkat, Christopher Mattocks, Daniel Ward, Sarah Ennis and Jay E. Self
Type: Article | 2017

Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study - Jue-Sheng Ong, Liang-Dar Hwang, Gabriel Cuellar-Partida, Nicholas G. Martin, Georgia Chenevix-Trench, Michael C J Quinn, Marilyn C Cornelis, Puya Gharahkhani, Penelope M. Webb, Stuart MacGregor and Diana Eccles
Type: Article | 2017

BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses - EmmanouilL S. Papadakis, T. Reeves, N.H. Robson, Thomas Maishman, Graham Packham and Ramsey Cutress
Type: Article | 2017

Towards personalised medicine in lung and thymus neuroendocrine tumours - Giuseppe Pelosi, Judith Cave and Christian H. Ottensmeier
Type: Article | 2017

T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria - Oanh Pham, Hope O'Donnell, Aymen Al-Shamkhani, Tobias Kerrinnes, Renne Tsolis and Stephen McSorley
Type: Article | 2017

Phase III, double-blind, randomized trial that compared maintenance lapatinib versus placebo after first-line chemotherapy in patients with human epidermal growth factor receptor 1/2-positive metastatic bladder cancer - Thomas Powles, Robert A. Huddart, Tony Elliott, Shah-Jalal Sarker, Charlotte Ackerman, Robert Jones, Syed Hussain, Simon Crabb, Satinder Jagdev, John Chester, Serena Hilman, Mark Beresford, Graham Macdonald, Sundar Santhanam, John A. Frew, Andrew Stockdale, Simon Hughes, Daniel Berney and Simon Chowdhury
Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: a post-hoc analysis of the New EPOC trial - Sian Pugh, Raphaele Thiebaut, John Bridgewater, Marie-Lise Grisoni, Karwan Moutasim, Francis Rousseau, Gareth Thomas, Gareth Griffiths, Francois Liebaert, John Primrose and Pierre Laurent-Puig
Type: Article | 2017

Autoimmunity/inflammation in a monogenic primary immunodeficiency cohort - William Rae, Daniel Ward, Christopher Mattocks, Yifang Gao, Reuben J. Pengelly, Sanjay V. Patel, Sarah Ennis, Saul Faust and Anthony P. Williams
Type: Article | 2017

Clinical efficacy of a next-generation sequencing gene panel for primary immunodeficiency diagnostics - William Rae, Daniel Ward, Christopher Mattocks, Reuben J. Pengelly, Efrem Eren, Sanjay V. Patel, Saul N. Faust, David Hunt and Anthony P. Williams
Type: Article | 2017

Anti-cytokine autoantibodies in a patient with a heterozygous NFKB2 mutation - Kesava Ramakrishnan, William Rae, Gabriela Barcenas-Morales, Yifang Gao, Reuben Pengelly, Sanjay Patel, Dinkantha Kumararatne, Sarah Ennis, Rainer Doffinger, Saul N. Faust and Anthony Williams
Type: Letter | 2017

Venous thromboembolism in metastatic urothelial carcinoma or variant histologies: incidence, associative factors, and effect on survival - Jorge D. Ramos, Martin F. Casey, Simon J. Crabb, Aristotelis Bamias, Lauren C Harshman, Yu-Ning Wong, Joaquim Bellmunt, Ugo De Giorgi, Sylvain Ladoire, Thomas Powles, Sumanta K. Pal, Guenter Niegisch, Federica Recine, Ajjai Alva, Neeraj Agarwal, Andrea Necchi, Ulka N. Vaishampayan, Jonathan E. Rosenberg, Matthew D. Galsky and Evan Y. Yu
Type: Article | 2017

Venous thromboembolism risk in patients with locoregional urothelial tract tumors - Jorge D. Ramos, Jonathan T. Wingate, Roman Gulati, Elizabeth R. Plimack, Lauren C. Harshman, Thomas Powles, Simon J. Crabb, Guenter Niegisch, Joaquim Bellmunt, Sylvain Ladoire, Ugo De Giorgi, Syed Hussain, Ajjai S. Alva, Jack Baniel, Neeraj Agarwal, Jonathan E. Rosenberg, Ulka N. Vaishampayan, Matthew D. Galsky and Evan Y. Yu
Type: Article | 2017

Pelvic exenteration with en bloc resection of the pelvic sidewall and intraoperative electron beam radiotherapy with Mobetron® for locally advanced rectal cancer - Karan Rangarajan, Rahul Bhome, N. Bateman, A. Naga, M. Simon, K. Donovan, Julian Smith and Alexander Mirnezami
Type: Article | 2017

Type: Review | 2017 | Item not available on this server.

“Stuff tailored to younger people, it’s like we don’t exist”: What young women want to know about surgery for early stage breast cancer - Alejandra Recio Saucedo, Anthony W. Gilbert, Sue Gerty, Ramsey I. Cutress, Diana Eccles and Claire Foster
Type: Article | 2017 | Item availability restricted.

Obinutuzumab induces superior B-Cell cytotoxicity to rituximab in rheumatoid arthritis and systemic lupus rrythematosus patient samples - Venkat Reddy, Christian Klein, David Isenberg, Martin Glennie, Geraldine Cambridge, Mark Cragg and Maria Leandro
Type: Article | 2017

Type: Article | 2017

Osteonecrosis following treatment for childhood acute lymphoblastic leukaemia: The Southampton Children's Hospital experience - A. Rhodes, J. Gray, N. Harvey, J.H. Davies, R.O.C. Oreffo, I. Reading, N.M.P. Clarke and A. Aarvold
Type: Article | 2017

Mastectomy skin flap necrosis: challenges and solutions - Stuart A. Robertson, Johann A. Jeevaratnam, Avi Agrawal and Ramsey I. Cutress
Type: Article | 2017

Akt signaling is critical for memory CD8+ T cell development and tumor immune surveillance - Anne Rogel, Jane E. Willoughby, Sarah L. Buchan, Henry J. Leonard, Stephen M. Thirdborough and Aymen Al-Shamkhani
Type: Article | 2017

In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis - Jatin Roper, Tuomas Tammela, Naniye Malli Cetinbas, Adam Akkad, Ali Roghanian, Steffen Rickelt, Mohammad Almeqdadi, Katherine Wu, Matthias A. Oberli, Francisco Sánchez-Rivera, Yoona K. Park, Xu Liang, George Eng, Martin S. Taylor, Roxana Azimi, Dmitriy Kedrin, Rachit Neupane, Semir Beyaz, Ewa T. Sicinska, Yvelisse Suarez, James Yoo, Lillian Chen, Lawrence Zukerberg, Pekka Katajisto, Vikram Deshpande, Adam J. Bass, Philip N. Tsichlis, Jacqueline Lees, Robert Langer, Richard O. Hynes, Jianzhu Chen, Arjun Bhutkar, Tyler Jacks and Ömer H. Yilmaz
Type: Article | 2017 | Item not available on this server.

Defining clonal plasticity using whole exome sequencing in single cells in an index case of amp1q21 multiple myeloma - Surinder Sahota, Dean Bryant, Nicola Weston-Bell, William Tapper, Arnold Bolomsky, Niklas Zojer and Andrew Collins
Type: Meeting abstract | 2017 | Item not available on this server.

Type: Article | 2017

Phase 1 study of inotuzumab ozogamicin combined with R-GDP for the treatment of patients with relapsed/refractory CD22+ B-cell non-Hodgkin lymphoma - Randeep Sangha, Andrew Davies, Nam H Dang, Michinori Ogura, David A MacDonald, Revathi Ananthakrishnan, M Luisa Paccagnella, Erik Vandendries, Joseph Boni and Yeow Tee Goh
Type: Article | 2017

Baseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls - Sibel Saya, Emma Killick, Sarah Thomas, Natalie Taylor, Elizabeth K. Bancroft, Jeanette Rothwell, Sarah Benafif, Alexander Dias, Christos Mikropoulos, Jenny Pope, Anthony Chamberlain, Ranga Gunapala, Louise Izatt, Lucy Side, Lisa Walker, Susan Tomkins, Jackie Cook, Julian Barwell, Vicki Wiles, Lauren Limb, Diana Eccles, Martin O. Leach, Susan Shanley, Fiona J. Gilbert, Helen Hanson, David Gallagher, Bala Rajashanker, Richard W. Whitehouse, Dow-Mu Koh, S. Aslam Sohaib, D. Gareth Evans and Rosalind A. Eeles
Type: Article | 2017

Improved prediction of endoxifen metabolism by CYP2D6 genotype in breast cancer patients treated with tamoxifen - Werner Schroth, Stefan Winter, Thomas Murdter, Elke Schaeffeler, Diana Eccles, Bryony Eccles, Balram Chowbay, Chiea C. Khor, Arafat Tfayli, Nathalie K. Zgheib, Michel Eichelbaum, Matthias Schwab and Hiltrud Brauch
Type: Article | 2017

An individual participant data meta-analysis of 13 randomized trials to evaluate the impact of prophylactic use of heparin in oncological patients - Holger Schunemann, Matthew Ventresca, Mark Crowther, Marcello Di Nisio, Matthias Briel, Qi Zhou, Simon Noble, Fergus Macbeth, Gareth Griffiths, David Garcia, Gary Lyman, Alfonso Iorio, Lawrance Mbuagbaw, Ignacio Neumann, Nick Van Es, Jan Brozek, Gordon Guyatt, Michael Streiff, Melissa Brouwers, Tejan Baldeh, Maura Marcucci, Ivan Florez, Ziad Solh, Walter Ageno, Suzanne Bleker, George Bozas, Harry Buller, Clara Klerk, Bernard Lebeau, Ramon Lecumberri, Robert McBane, Kostandinos Sideras, Anthony Maraveyas, Uwe Pelzer, Charles Loprinzi, Patrick M. Bossuyt, Lara Kahale, Elie A. Akl and Gilbert Zulian
Type: Conference or Workshop Item | 2017 | Item not available on this server.

Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival after neoadjuvant chemotherapy - Roland Seiler, Hussam Al Deen Ashab, Nicholas Erho, Bas W.G. van Rhijn, Brian Winters, James Douglas, Kim E. Van Kessel, Elisabeth E. Fransen van de Putte, Matthew Sommerlad, Natalie Q. Wang, Voleak Choeurng, Ewan A. Gibb, Beatrix Palmer-Aronsten, Lucia L. Lam, Christine Buerki, Elai Davicioni, Gottfrid Sjödahl, Jordan Kardos, Katherine A. Hoadley, Seth P. Lerner, David J. McConkey, Woonyoung Choi, William Y. Kim, Bernhard Kiss, George N. Thalmann, Tilman Todenhöfer, Simon J. Crabb, Scott North, Ellen C. Zwarthoff, Joost L. Boormans, Jonathan Wright, Marc Dall'Era, Michiel S. van der Heijden and Peter C. Black
Type: Article | 2017 | Item availability restricted.

An oncofetal glycosaminoglycan modification provides therapeutic access to cisplatin-resistant bladder cancer - Roland Seiler, Htoo Zarni Oo, Davide Tortora, Thomas M. Clausen, Chris K. Wang, Gunjan Kumar, Marina Ayres Pereira, Maj S. Ørum-Madsen, Mette Ø. Agerbæk, Tobias Gustavsson, Mie A. Nordmaj, Jamie R. Rich, Nada Lallous, Ladan Fazli, Sherry S. Lee, James Douglas, Tilman Todenhöfer, Shaghayegh Esfandnia, Dulguun Battsogt, John S. Babcook, Nader Al-Nakouzi, Simon J. Crabb, Igor Moskalev, Bernhard Kiss, Elai Davicioni, George N. Thalmann, Paul S. Rennie, Peter C. Black, Ali Salanti and Mads Daugaard
Type: Article | 2017

Accuracy of drain readings by surgical healthcare professionals - S. Shankla, T.C. Biggs, H.J. Cox and E.V. King
Type: Letter | 2017 | Item not available on this server.

Type: Thesis | 2017 | University of Southampton

Type: Article | 2017 | Item not available on this server.

The diagnostic accuracy of a single CEA blood test in detecting colorectal cancer recurrence: results from the FACS trial - Bethany Shinkins, Brian D. Nicholson, John Primrose, Rafael Perera, Timothy James, Sian Pugh and David Mant
Type: Article | 2017

Type: Article | 2017 | Item availability restricted.

Prevention of morbidity in sickle cell disease phase II (Improvement of cognition in children with Sickle Cell Disease with auto-adjusting Continuous Positive Airways Pressure: Phase II) (POMS 2b paediatric cohort) - April E. Slee, Jamie M. Kawadler, Melanie Koelbel, Hanne Stotesbury, David C. Rees, Maria Pelidis, Jo Howard, Swee Lay Thein, Simon Skene, Sahota Sati, Carol Nwosu, Maureen Gwam, Dawn Saunders, Johanna C. Gavlak, Gupta Atul, Simrat Sarkaria, Christina Liossi, Fenella J. Kirkham and Baba Inusa
Type: Meeting abstract | 2017 | Item not available on this server.

Fibroblasts derived from oesophageal adenocarcinoma differ in DNA methylation profile from normal oesophageal fibroblasts - Eric Smith, Helen M. Palethorpe, Annette Hayden, Joanne Young, Timothy Underwood and Paul Drew
Type: Article | 2017

Novel splice-switching oligonucleotide promotes BRCA1 aberrant splicing and susceptibility to PARP inhibitor action - Lindsay Smith, Flavia Leme De Calais, Michela Raponi, Massimiliano Mellone, Emanuele Buratti, Jeremy Blaydes and Diana Baralle
Type: Article | 2017

JACIE accreditation for blood and marrow transplantation: past, present and future directions of an international model for healthcare quality improvement - J A Snowden, E McGrath, R F Duarte, R Saccardi, K. Orchard, N Worel, J Kuball, C Chabannon and M Mohty
Type: Article | 2017 | Item not available on this server.

A comparison of the clinical effectiveness and cost of specialised individually delivered parent training for preschool attention-deficit/hyperactivity disorder and a generic, group-based programme: a multi-centre, randomised controlled trial of the New Forest Parenting Programme versus Incredible Years - Edmund J.S. Sonuga-Barke, Joanne Barton, David Daley, Judy Hutchings, Tom Maishman, James Raftery, Louise Stanton, Cathy Laver-Bradbury, Maria Chorozoglou, David Coghill, Louisa Little, Martin Ruddock, Mike Radford, Guiqing Lily Yao, Louise Lee, Lisa Gould, Lisa Shipway, Pavlina Markomichali, James McGuirk, Michelle Lowe, Elvira Perez, Joanna Lockwood and Margaret J.J. Thompson
Type: Article | 2017

miR-196b-5p regulates colorectal cancer cell migration and metastasis through interaction with HOXB7 and GALNT5 - Verena Stiegelbauer, Petra Vychytilova-faltejskova, Michael Karbiener, Anna-maria Pehserl, Andreas Reicher, Margit Resel, Ellen Heitzer, Cristina Ivan, Marc Bullock, Hui Ling, Alexander Deutsch, Annika Wulf-goldenberg, Jan Basri Adiprasito, Herbert Stoeger, Johannes Haybaeck, Marek Svoboda, Michael Stotz, Gerald Hoefler, Ondrej Slaby, George Adrian Calin, Armin Gerger and Martin Pichler
Type: Article | 2017 | Item not available on this server.

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch - Joanne Tod, Christopher Hanley, Mark R. Morgan, Marta Rucka, Toby Mellows, Maria-Antoinette Lopez, Philip Kiely, Karwan Moutasim, Steven, James Frampton, Durgagauri Sabnis, David R. Fine, Colin Johnson, John F. Marshall, Giorgio Scita, Veronika Jenei and Gareth Thomas
Type: Article | 2017

Type C TP53-CDKN1A pathway dysfunction occurs independently of CDKN1A gene polymorphisms in chronic lymphocytic leukaemia and is associated with TP53 abnormalities - Ian Tracy, William Tapper, Anton Parker, Anne Gardiner, Shalal Sadullah, Guy Pratt, Adrian Copplestone, David Oscier and Oliver Giles Best
Type: Letter | 2017 | Item not available on this server.

The National Institute for Health and Care Excellence (NICE) Guidance on Bladder Cancer; a step in the right direction? - S. Trainor, A. Choudhury, R. Huddart, A.E. Kiltie, R. Kockelbergh, W. Turner, A. Birtle and S.J. Crabb
Type: Editorial | 2017 | Item availability restricted.

TLR-3/9 agonists synergize with anti-ErbB2 mAb-Letter - Anna H. Turaj, Lekh N. Dahal, Stephen A. Beers, Mark S. Cragg and Sean H. Lim
Type: Letter | 2017

Antibody tumor targeting is enhanced by CD27 agonists through myeloid recruitment - Anna H. Turaj, Khiyam Hussain, Kerry L. Cox, Matthew J.J. Rose-Zerilli, James Testa, Lekh N. Dahal, H.T. Claude Chan, Sonya James, Vikki L. Field, Matthew J. Carter, Hyung J. Kim, Jonathan J. West, Lawrence J. Thomas, Li-Zhen He, Tibor Keler, Peter W.M. Johnson, Aymen Al-Shamkhani, Stephen M. Thirdborough, Stephen A. Beers, Mark S. Cragg, Martin J. Glennie and Sean H. Lim
Type: Article | 2017

The development, application and analysis of an enhanced recovery programme for major oesophagogastric resection - T.J. Underwood, F. Noble, N. Madhusudan, D. Sharland, R. Fraser, J. Owsley, M. Grant, J.J. Kelly and J.P. Byrne
Type: Article | 2017

The Khorana Score for the prediction of venous thromboembolism in patients with solid cancer: An individual patient data meta-analysis - Nick Van Es, Matthew Ventresca, Qi Zhou, Simon Noble, Mark Crowther, Marcello Di Nisio, Matthias Briel, David Garcia, Gary Lyman, Fergus Macbeth, Gareth Griffiths, Alfonso Iorio, Lawrance Mbuagbaw, Ignacio Neumann, Jan Brozek, Gordon Guyatt, Michael Streiff, Melissa Brouwers, Tejan Baldeh, Ivan Florez, Ziad Solh, Walter Ageno, Maura Marcucci, George Bozas, Anthony Maraveyas, Bernard Lebeau, Gilbert Zulian, Ramon Lecumberri, Kostandinos Sideras, Charles Loprinzi, Robert McBane, Suzanne Bleker, Uwe Pelzer, Elie A. Akl, Patrick M. Bossuyt, Lara Kahale, Harry Buller, Clara Klerk and Holger Schunemann
Type: Conference or Workshop Item | 2017 | Item not available on this server.

Type: Conference or Workshop Item | 2017 | Item not available on this server.

Direct evidence for conformational dynamics in Major Histocompatibility Complex class I molecules: Evidence for conformational dynamics in MHC I allotypes - Andrew Van Hateren, Malcom Anderson, Alistair Bailey, Jorn M. Werner, Paul J. Skipp and Timothy Elliott
Type: Article | 2017

Type: Review | 2017

Expanded carrier screening: what determines intended participation and can this be influenced by message framing and narrative information? - Jan S. Voorwinden, Anne H. Buitenhuis, Erwin Birnie, Anneke M. Lucassen, Marian A. Verkerk, Irene M. Van Langen, Mirjam Plantinga and Adelita V. Ranchor
Type: Article | 2017 | Item not available on this server.

Oesophageal cancer - Robert C. Walker and Timothy J. Underwood
Type: Review | 2017

IL-12 and IL-7 synergise to control MAIT cell cytotoxic responses to bacterial infection - Joshua C. Wallington, Anthony P. Williams, Karl J. Staples and Tom MA Wilkinson
Type: Article | 2017

Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells - W.R. Wan Makhtar, G. Browne, A. Karountzos, C. Stevens, Y. Alghamdi, A.R. Bottrill, S. Mistry, E. Smith, M. Bushel, J.H. Pringle, A.E. Sayan and E. Tulchinsky
Type: Article | 2017

Plant viral vaccine delivery as a platform to induce cellular immunity against cancer antigens - Chuan Wang, Yidao Wang, Alexandra J Allen, Jantipa Jobsri, Christian. H Ottensmeier, Surinder Sahota and Natalia Savelyeva
Type: Conference or Workshop Item | 2017 | Item availability restricted.

Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial - Michael Wang, Simon Rule, Pier Luigi Zinzani, Andre Goy, Olivier Casasnovas, Stephen D. Smith, Gandhi Damaj, Jeanette Doorduijn, Thierry Lamy, Franck Morschhauser, Carlos Panizo, Bijal Shah, Andrew Davies, Richard Eek, Jehan Dupuis, Eric Jacobsen, Arnon P. Kater, Steven Le Gouill, Lucie Oberic, Taduesz Robak, Todd Covey, Richa Dua, Ahmed Hamdy, Xin Huang, Raquel Izumi, Priti Patel, Wayne Rothbaum, J. Greg Slatter and Wojciech Jurczak
Type: Article | 2017 | Item not available on this server.

Type: Article | 2017

The effects of exercise on pain, fatigue, insomnia, and health perceptions in patients with operable advanced stage rectal cancer prior to surgery: a pilot trial - Malcolm West, Lisa Loughney, Gareth Ambler, Borislav Dimitrov, Jamie Kelly, Monty Mythen, Richard Sturgess, Peter Claverley, Michael Grocott and Sandy Jack
Type: Article | 2017 | Item not available on this server.

Type: Book Section | 2017 | Item not available on this server.

Prehabilitation and nutritional support to improve perioperative outcomes - Malcolm A. West, Paul E. Wischmeyer and Michael P.W. Grocott
Type: Article | 2017

Type: Book Section | 2017 | Humana Press | Item not available on this server.

Development of the EORTC QLQ-CAX24, a questionnaire for cancer patients with cachexia - S.J. Wheelwright, J.B. Hopkinson, A.-S. Darlington, D.F. Fitzsimmons, P. Fayers, T.R. Balstad, A. Bredart, E. Hammerlid, S. Kaasa, O. Nicolatou-Galitis, M. Pinto, H. Schmidt, T.S. Solheim, F. Strasser, I.M. Tomaszewska and C.D. Johnson
Type: Article | 2017

A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD - Tom M.A. Wilkinson, Emmanuel Aris, Simon Bourne, Stuart C. Clarke, Mathieu Peeters, Thierry G. Pascal, Sonia Schoonbroodt, Andrew C. Tuck, Viktoriya Kim, Kristoffer Ostridge, Karl J. Staples, Nicholas Williams, Anthony Williams, Stephen Wootton and Jeanne-Marie Devaster
Type: Article | 2017

OX40: structure and function – what questions remain? - Jane Willoughby, Jordana Griffiths, Ivo Tews and Mark Cragg
Type: Article | 2017

Randomized clinical trial of open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery after surgery programme (ORANGE II study) - E.M. Wong-Lun-Hing, R.M. van Dam, G.J.P. van Breukelen, P.J. Tanis, F. Ratti, R. van Hillegersberg, G.D. Slooter, J.H.W. de Wilt, M.S.L. Liem, M.T. de Boer, J.M. Klaase, U.P. Neumann, L.A. Aldrighetti, C.H.C. Dejong, John Primrose and Mohammad Abu Hilal
Type: Article | 2017

Head and neck squamous cell carcinomas are characterized by a stable immune signature within the primary tumor over time - Oliver Wood, James Clarke, Jeogmin Woo, Adal H. Mirza, Christopher H. Woelk, Gareth J. Thomas, Pandurangan Vijayanand, Emma V. King and Christian H. Ottensmeier
Type: Article | 2017

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia - E Young, D Noerenberg, L Mansouri, V Ljungström, M Frick, L-A Sutton, S J Blakemore, J Galan-Sousa, K Plevova, P Baliakas, D Rossi, R Clifford, D Roos-Weil, V Navrkalova, B Dörken, C A Schmitt, K E Smedby, G Juliusson, B Giacopelli, J S Blachly, C Belessi, P Panagiotidis, N Chiorazzi, F Davi, A W Langerak, D Oscier, A Schuh, G Gaidano, P Ghia, W Xu, L Fan, O A Bernard, F Nguyen-Khac, L Rassenti, J Li, T J Kipps, K Stamatopoulos, S Pospisilova, T Zenz, C C Oakes, J C Strefford, R Rosenquist and F Damm
Type: Article | 2017 | Item not available on this server.

Improving antibody-based cancer therapeutics through glycan engineering - Xiaojie Yu, Michael Marshall, Mark Cragg and Max Crispin
Type: Article | 2017

Final results of the IELSG-19 Randomized Trial of Mucosa-Associated Lymphoid Tissue Lymphoma: improved event-free and progression-free survival with Rituximab plus Chlorambucil versus either Chlorambucil or Rituximab monotherapy - Emanuele Zucca, Annarita Conconi, Giovanni Martinelli, Reda Bouabdallah, Alessandra Tucci, Umberto Vitolo, Maurizio Martelli, Ruth Pettengell, Gilles Salles, Catherine Sebban, Armando Lopez Guillermo, Graziella Pinotti, Liliana Devizzi, Franck Morschhauser, Hervé Tilly, Valter Torri, Stefan Hohaus, Andrés J.M. Ferreri, Pierre Zachée, André Bosly, Corinne Haioun, Caterina Stelitano, Monica Bellei, Maurilio Ponzoni, Christiane Copie-Bergman, Andrew Jack, Elias Campo, Luca Mazzucchelli, Franco Cavalli, Peter Johnson and Catherine Thieblemont
Type: Article | 2017

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