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Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences
Cancer Sciences" and Year is 2021

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Number of items: 174.

Comparative analysis of gene expression platforms for cell-of-origin classification of diffuse large B-cell lymphoma shows high concordance - Sophia Ahmed, Paul Glover, Jan Taylor, Chulin Sha, Matthew A Care, Reuben Tooze, Andrew Davies, David R Westhead, Peter W M Johnson, Catherine Burton and Sharon L Barrans
Type: Article | 2021

Type: Dataset | 2021 | University of Southampton

Nanoscale imaging of the functional anatomy of the brain - Misa Arizono, Stéphane Bancelin, Philipp Bethge, Ronan Chéreau, Agata Idziak, V.V.G. Krishna Inavalli, Thomas Pfeiffer, Jan Tønnesen and U. Valentin Nägerl
Type: Article | 2021 | Item not available on this server.

Super‐resolution shadow imaging reveals local remodeling of astrocytic microstructures and brain extracellular space after osmotic challenge - Misa Arizono, V V G Krishna Inavalli, Stéphane Bancelin, Mónica Fernández-Monreal and U Valentin Nägerl
Type: Article | 2021 | Item not available on this server.

Cover Image, Volume 69, Issue 6 - Misa Arizono, V.V.G. Krishna Inavalli, Stéphane Bancelin, Mónica Fernández‐Monreal and U. Valentin Nägerl
Type: Article | 2021 | Item availability restricted.

Efficacy and safety results from CheckMate 140, a phase 2 study of nivolumab for relapsed/refractory follicular lymphoma - Philippe Armand, Ann Janssens, Giuseppe Gritti, John Radford, John Timmerman, Antonio Pinto, Santiago Mercadal Vilchez, Peter Johnson, David Cunningham, John P Leonard, Scott J Rodig, Patricia Martín-Regueira, Anne Sumbul, Selda Samakoglu, Hao Tang and Stephen M Ansell
Type: Article | 2021

Comparison of immunohistochemistry and gene expression profiling subtyping for diffuse large B-cell lymphoma in the phase III clinical trial of R-CHOP ± ibrutinib - Sriram Balasubramanian, Songbai Wang, Christopher Major, Brendan Hodkinson, Michael Schaffer, Laurie H Sehn, Peter Johnson, Pier Luigi Zinzani, Jodi Carey, S Martin Shreeve, Steven Sun, John Gerecitano, Jessica Vermeulen, Louis M Staudt and Wyndham Wilson
Type: Article | 2021

Experiences of adolescents living with Silver-Russell syndrome - Lisa Ballard, Elizabeth Jenkinson, Christopher Byrne, Jenny Child, Hazel Inskip, Oluwakemi Lokulo-Sodipe, Deborah Mackay, Emma Wakeling, Justin Davies, Karen Temple and Angela J Fenwick
Type: Article | 2021

Structure–activity studies of 3,9-diazaspiro[5.5]undecane-based γ-aminobutyric acid type A receptor antagonists with immunomodulatory effect - Francesco Bavo, Heleen De-jong, Jonas Petersen, Christina Birkedahl Falk-petersen, Rebekka Löffler, Emma Sparrow, Frederik Rostrup, Jannik Nicklas Eliasen, Kristine S. Wilhelmsen, Kasper Barslund, Christoffer Bundgaard, Birgitte Nielsen, Uffe Kristiansen, Petrine Wellendorph, Yury Bogdanov and Bente Frølund
Type: Article | 2021

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element - Joseph S. Baxter, Nichola Johnson, Katarzyna Tomczyk, Andrea Gillespie, Sarah Maguire, Rachel Brough, Laura Fachal, et al. and Olivia Fletcher
Type: Article | 2021 | Item not available on this server.

Using DNA sequencing data to quantify T cell fraction and therapy response - Robert Bentham, Kevin Litchfield, Thomas B.K. Watkins, Emilia L. Lim, Rachel Rosenthal and Carlos Martínez-Ruiz
Type: Article | 2021 | Item not available on this server.

Man Vs Machine – Automated Colonoscopy Withdrawal Time Calculation VS Endoscopist Self-Report - M Bhandari, L Hlaing, H Phan, F Borca, K Cowin, R Beegan, J Geeson, J Batchelor, R Nouraei, D Cable, I Rahman and M Stammers
Type: Conference or Workshop Item | 2021 | Item not available on this server.

OTU-18 Silence of the LAMS: reducing risk in EUS guided drainage of pancreatic fluid collections - Megha Bhandari, Puneet Chhabra, Matthew Stammers, Nadeem Tehami and Ben Maher
Type: Meeting abstract | 2021 | Item not available on this server.

Metabolic syndrome is a predictor of all site and liver-specific recurrence following primary resection of colorectal cancer: Prospective cohort study of 1006 patients - Rahul Bhome, Konstantina Peppa, Shoura Mohamedelmustafa Ali Karar, Declan McDonnell, Alexander Mirnezami and Zaed Z R Hamady
Type: Article | 2021

Type: Review | 2021

P041. Systematic review of surgical and patient reported outcomes of neoadjuvant endocrine therapy for breast cancer - Beatrice Brett, Constantinos Savva, Lucy Davies, Michael Douek, Ellen Copson and Ramsey Cutress
Type: Meeting abstract | 2021 | Item not available on this server.

Type: Letter | 2021

Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study - Ewan Carr, Rebecca Bendayan, Daniel Bean, Hang T.T. Phan, Ting Shi and James Batchelor
Type: Article | 2021

Potential of magnetic hyperthermia to stimulate localized immune activation - Thomas J. Carter, Giulia Agliardi, Fang Yu Lin, Matthew Ellis, Clare Jones, Mathew Robson, Angela Richard-Londt, Paul Southern, Mark Lythgoe, May Zaw Thin, Vyacheslav Ryzhov, Rafael T.M. de Rosales, Cordula Gruettner, Maha R.A. Abdollah, R. Barbara Pedley, Quentin A. Pankhurst, Tammy L. Kalber, Sebastian Brandner, Sergio Quezada, Paul Mulholland, Maxim Shevtsov and Kerry Chester
Type: Article | 2021

The synthesis of biologically active indolocarbazole natural products - George Edward Chambers, Abdulkadir Emre Sayan and Richard C.D. Brown
Type: Article | 2021

Treatment outcomes for small cell carcinoma of the bladder: results from a UK patient retrospective cohort study - C Chau, Y Rimmer, A Choudhury, D Leaning, A Law, D Enting, J H Lim, S Hafeez, V Khoo, R Huddart, D Mitchell, D R Henderson, J McGrane, M Beresford, N Vasudev, S Beesley, S Hilman, C Manetta, R Sriram, A Sharma, C Eswar, S Treece, M Vilarino-Varela, M Varughese, H Glen, E Pintus and S Crabb
Type: Article | 2021

Nervous and muscular adverse events after covid‐19 vaccination: A systematic review and meta‐analysis of clinical trials - Jiaxin Chen, Yuangui Cai, Yicong Chen, Anthony P. Williams, Yifang Gao and Jinsheng Zeng
Type: Review | 2021

Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior - Giorgia Chiodin, Joel D Allen, Dean Bryant, Philip Rock, Enrica Antonia Martino, Beatriz Valle-Argos, Patrick J Duriez, Yasunori Watanabe, Isla Henderson, James S Blachly, Katy J McCann, Jonathan C Strefford, Graham Packham, Teunis Bh Geijtenbeek, Carl Figdor, George Wright, Louis Michael Staudt, Richard Burack, Thomas Bowden, Max Crispin, Freda Kathryn Stevenson and Francesco Forconi
Type: Article | 2021

MANagement gUidelinEs for Low Anterior Resection Syndrome the MANUEL project - Peter Christensen, Coen Im Baeten, Eloy Espín-Basany, Jacopo Martellucci, Karen P Nugent, Frank Zerbib, Gianluca Pellino and Harald Rosen
Type: Article | 2021

Type: Article | 2021

Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease - Tracy Coelho, Eva Riethmacher, Yifang Gao, Enrico Mossotto, Alisher Khojanazarov, Ann Griffin, Saida Mukanova, Aiymkul Ashimkanova, Rachel Haggarty, Anton Borissenko, James Ashton, Imogen Sian Stafford, Akshay Batra, Nadeem A. Afzal, Michael P. Stanton, Bhumita Vadgama, Kapura Adrisova, Robert Beattie, Anthony Williams, Sarah Ennis and Dieter Riethmacher
Type: Article | 2021

Type: Article | 2021

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers - Juliette Coignard, Michael Lush, Jonathan Beesley, Tracy A O'Mara, Joe Dennis and Jonathan P Tyrer
Type: Article | 2021

Type: Dataset | 2021 | Zenodo | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia - Mark Cragg, Johannes Bloehdorn, Andrejs Braun, Amaro Taylor-Weiner, Billy Michael Chelliah Jebaraj, Sandra Robrecht, Julia Krzykalla, Heng Pan, Adam Giza, Gulnara Akylzhanova, Karlheinz Holzmann, Annika Scheffold, Harvey E. Johnston, Ru-Fang Yeh, Tetyana Klymenko, Barbara Eichorst, Lars Bullinger, Kirsten Fischer, Martin Weisser Weisser, Tadeusz Robak, Christof Schneider, John Gribben, Lekh N Dahal, Matthew J. Carter, Oliver Elemento, Dan A. Landau, Donna S. Neuberg, Mark S. Cragg, Axel Benner, Michael Hallek, Catherine J Wu, Hartmut Dohner, Stephan Stilgenbauer and Daniel Mertens
Type: Article | 2021

Type: Article | 2021 | Item availability restricted.

Rethinking value construction in biomedicine and healthcare - Saheli Datta Burton, Katharina Kieslich, Katharina Paul, Gabrielle Samuel and Barbara Prainsack
Type: Article | 2021

Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK 'Alert Level 4' phase of the B-MaP-C study - Rajiv V Dave, Baek Kim, Alona Courtney, Elizabeth M Camacho, Patricia Fairbrother, Ellen Copson and Ramsey I Cutress
Type: Article | 2021 | Item not available on this server.

Type: Editorial | 2021 | Item availability restricted.

An IRF1-IRF4 toggle-switch controls tolerogenic and immunogenic transcriptional programming in human Langerhans cells - James Davies, Andres F. Vallejo, Sofia Sirvent, Gemma Porter, Kalum Clayton, Yamkela Qumbelo, Patrick Stumpf, Jonathan West, Clive Gray, Nyaradzo Chigorimbo-Murefu, Benjamin Macarthur and Marta Polak
Type: Article | 2021

Oesophageal cancer: the effect of early nutrition support on clinical outcomes - S.J. Davies, Malcolm West, Saqib A Rahman, Timothy Underwood and L.V. Marino
Type: Article | 2021

Rituximab and obinutuzumab differentially hijack the B-cell receptor and NOTCH1 signaling pathways - Jennifer Edelmann, Arran D. Dokal, Emma Vilventhraraja, Karlheinz Holzmann, David Britton, Tetyana Klymenko, Hartmut Döhner, Mark Cragg, Andrejs Braun, Pedro Cutillas and John G. Gribben
Type: Article | 2021

What is the role of the surgeon in the management of head and neck mucosal melanoma in the immunotherapy era? - Mark Edmond, Pablo Nenclares, Kevin Harrington, Derfel Ap Dafydd, Izhar Bagwan, Donna Begg, Ken Lingley, Gillian Patterson, Miranda Payne, Neil Steven, Nancy Turnbull, Kent Yip, Priyamal Silva, Cyrus Kerawala, Vinidh Paleri and Emma King
Type: Article | 2021 | Item availability restricted.

Type: Book Section | 2021 | Octaedro | Item not available on this server.

Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients - M. Eltahir, E. Fletcher, L. Dynesius, J.L. Jarblad, M. Lord, I. Laurén, M. Zekarias, X. Yu, M.S. Cragg, C. Hammarström, K.H. Levedahl, M. Höglund, G. Ullenhag, M. Mattsson and S.M. Mangsbo
Type: Article | 2021 | Item not available on this server.

Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy - Simon Eschweiler, James Clarke, Ciro Ramírez-suástegui, Bharat Panwar, Ariel Madrigal, Serena J. Chee, Ioannis Karydis, Edwin Woo, Aiman Alzetani, Somaia Elsheikh, C. J. Hanley, G. J. Thomas, Peter S. Friedmann, Tilman Sanchez-elsner, Ferhat Ay, Christian H. Ottensmeier and Pandurangan Vijayanand
Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma - Katharina Filipski, Michael Scherer, Kim N. Zeiner, Andreas Bucher, Johannes Kleemann, Philipp Jurmeister, Tabea I. Hartung, Markus Meissner, Karl H. Plate, Tim R. Fenton, Jörn Walter, Sascha Tierling, Bastian Schilling, Pia S. Zeiner and Patrick N. Harter
Type: Article | 2021

Selinexor enhances NK cell activation against malignant B cells via downregulation of HLA-E - Jack, Graham Fisher, Salim Khakoo, Mark Cragg, Francesco Forconi, Peter Johnson, Amber Doyle, christopher Walker, yosef landesman and Matthew Blunt
Type: Article | 2021

Early-Onset Colorectal Adenocarcinoma in the IDEA Database: Treatment Adherence, Toxicities, and Outcomes With 3 and 6 Months of Adjuvant Fluoropyrimidine and Oxaliplatin - Elisa Fontana, Jeff Meyers, Alberto Sobrero, Timothy Iveson, Anthony F Shields, Julien Taieb, Takayuki Yoshino, Ioannis Souglakos, Elizabeth C Smyth, Florian Lordick, Markus Moehler, Anne Giraut, Andrea Harkin, Roberto Labianca, Jeffrey Meyerhardt, Thierry André, Ioannis Boukovinas, Sara Lonardi, Mark Saunders, Dewi Vernerey, Eiji Oki, Vassilis Georgoulias, Irit Ben-Aharon and Qian Shi
Type: Article | 2021 | Item availability restricted.

Type: Dataset | 2021 | University of Southampton

Critical evaluation of the methodology used by Wilson-Davies et al., (2020) entitled “Concerning the OptiGene Direct LAMP assay, and it`s use in at-risk groups and hospital staff” - Veronica Fowler, Angela Douglas, Keith Godfrey, Anthony Williams, Andrew Beggs, Stephen Kidd, Nick Cortes, Mark Wilcox, Kerrie Davies, Melanie Smith and Sue Hill
Type: Letter | 2021

A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial - Christopher P. Fox, Ayesha S. Ali, Graham McIlroy, Steffi Thust, Nicolás Martinez-Calle, Aimee E. Jackson, Louise M. Hopkins, Catherine M. Thomas, Shireen Kassam, Josh Wright, Sridhar Chaganti, Jeffery Smith, Ian Chau, Dominic Culligan, Kim M. Linton, Graham P. Collins, Andrés J. M. Ferreri, David Lewis, Andrew J. Davies, Rod Johnson, Dorothee P. Auer and Kate Cwynarski
Type: Article | 2021

Developing a 3D B cell Lymphoma culture system to model antibody therapy - Russell Foxall, Priyanka Narang, Bridget Glaysher, Elin Hub, Emma Louise Teal, Mark C. Coles, Margaret Ashton-Key, Stephen Beers and Mark Cragg
Type: Article | 2021

Ethnicity and breast cancer in the UK: Where are we now? - Toral Gathani, Anushka Chaudhry, Leena Chagla, Sharat Chopra, Ellen Copson, Arnie Purushotham, Raghavan Vidya and Ramsey Cutress
Type: Article | 2021

Current landscape of nutrition within prehabilitation oncology research: A scoping review - Chelsia Gillis, Sarah J. Davies, Francesco Carli, Paul E. Wischmeyer, Stephen A. Wootton, Alan A. Jackson, Bernhard Riedel, Luise V. Marino, Denny Z. H. Levett and Malcolm A. West
Type: Article | 2021

Nutrition care process model approach to surgical prehabilitation in oncology - Chelsia Gillis, Leslee Hasil, Popi Kasvis, Neil Bibby, Sarah J Davies, Carla M Prado, Malcolm A West and Clare Shaw
Type: Review | 2021

Bile leakage after laparoscopic and open liver resection; incidence and clinical impact: an international multicenter propensity score-matched study of 13,379 patients - Burak Gorgec, Andrea Cacciaguerra, Federica Cipriani, Francesca Ratti, Nadia Russolillo, Jacopo Lanari, Ra'ed Al-Jarrah, Davit Aghayan, John Primrose, Felice Giuliante, Mathieu D'Hondt, Fernando Rotellar, David Fuks, Santiago Lopez-Ben, Marco Vivarelli, Bjorn Edwin, Umberto Cillo, Alessandro Ferrero, Luca Antonio Aldrighetti, Marc G. Besselink and Mohammed Abu-Hilal
Type: Article | 2021

Type: Article | 2021

Paediatric ambiguous lineage leukaemia with monocytic differentiation at diagnosis: case series and review of literature - Juliet Gray, Sneha Tandon, Reginah Visser, Emma Astwood, Jeanette Payne, Juliet Gray, Lucy Wheeler, Julie Irving and Paul Virgo
Type: Letter | 2021 | Item not available on this server.

Hematopoietic stem cell transplantation for autoimmune diseases in the time of COVID-19: EBMT guidelines and recommendations - Raffaella Greco, Tobias Alexander, Joachim Burman, Nicoletta Del Papa, Jeska de Vries-Bouwstra and Dominique Farge
Type: Article | 2021

SafeFit Trial: virtual clinics to deliver a multimodal intervention to improve psychological and physical well-being in people with cancer. Protocol of a COVID-19 targeted non-randomised phase III trial - Chloe Grimmett, Andrew Bates, Malcolm West, Samantha Leggett, Judit Varkonyi-Sepp, Anna Campbell, June Davis, Stephen Wootton, Clare Shaw, Rachael Barlow, Joanna Ashcroft, Andrew Scott, Helen Moyes, Lesley Hawkins, Denny Z H Levett, Fran Williams, Michael P W Grocott and Sandy Jack
Type: Article | 2021

Should you trust the radiologist? - Sun Mi Ha, Donal Sheehan, Ahmed Shalabi, Malcolm A West, Rajapandian Ilangovan, Morgan Moorghen, John T Jenkins and Siwan Thomas-Gibson
Type: Letter | 2021 | Item not available on this server.

The Impact on Anti-Mullerian Hormone (AMH), uterine fibroid size and uterine artery patency following Uterine Fibroid Embolization (UFE) with a resorbable embolic agent - Nigel Hacking, Ganesh Vigneswaran, Drew Maclean, Timothy Bryant, Sameer Umranikar, Ying Cheong and Sachin Modi
Type: Article | 2021

Camidanlumab tesirine in patients with relapsed or refractory lymphoma: a phase 1, open-label, multicentre, dose-escalation, dose-expansion study - Mehdi Hamadani, Graham P Collins, Paolo F Caimi, Felipe Samaniego, Alexander Spira, Andrew Davies, John Radford, Tobias Menne, Anand Karnad, Jasmine M Zain, Paul Fields, Karin Havenith, Hans G Cruz, Shui He, Joseph Boni, Jay Feingold, Jens Wuerthner and Steven Horwitz
Type: Article | 2021

Engineering and clinical use of artificial intelligence (AI) with machine learning and data science advancements: radiology leading the way for future - B M Zeeshan Hameed, Gayathri Prerepa, Vathsala Patil, Pranav Shekhar, Syed Zahid Raza, Hadis Karimi, Rahul Paul, Nithesh Naik, Sachin Modi, Ganesh Vigneswaran, Bhavan Prasad Rai, Piotr Chłosta and Bhaskar K Somani
Type: Review | 2021

Type: Article | 2021 | Item not available on this server.

Three versus six months of adjuvant doublet chemotherapy for patients with colorectal cancer: A multi-country cost-effectiveness and budget impact analysis - Catherine R. Hanna, Jose A. Robles-Zurita, Andrew Briggs, Andrea Harkin, Caroline Kelly, John McQueen, Karen Allan, Sarah Pearson, Henrik Hollander, Bengt Glimelius, Ramon Salazar, Eva Segelov, Mark Saunders, Tim Iveson, Robert J. Jones and Kathleen A. Boyd
Type: Article | 2021

CD8 T-cell-mediated cerebellitis directed against Purkinje cell antigen after ipilimumab for small cell lung cancer - Marc Hardwick, Luke Nolan, James Nicoll, Sanjay Jogai, Edurne Arriola, Debora Joseph-Pietras, Jeanette Norman, Christian Ottensmeier and Ian Galea
Type: Article | 2021

Dual Dean entrainment with volume ratio modulation for efficient droplet co-encapsulation: extreme single-cell indexing - Jack Harrington, Luis Blay Esteban, Jonathan Butement, Andres F. Vallejo, Simon I.R. Lane, Bhavwanti Sheth, Maaike S.A. Jongen, Rachel Parker, Patrick S. Stumpf, Rosanna C.G. Smith, Ben D. MacArthur, Matthew J.J. Rose-Zerilli, Marta E. Polak, Tim Underwood and Jonathan West
Type: Article | 2021

Micro RNA targets in HIV latency: Insights into novel layers of latency control - Ashley I. Heinson, Jeongmin Woo, Amey Mukim, Cory H. White, Bastiaan Moesker, Alberto Bosque, Celsa A. Spina, Christopher H. Woelk, Ben D. Macarthur and Nadejda Beliakova-Bethell
Type: Article | 2021 | Item availability restricted.

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study - Julia Hippisley-Cox, Carol A.C. Coupland, Nisha Mehta, Ruth H. Keogh, Karla Diaz-Ordaz, Kamlesh Khunti, Ronan A. Lyons, Frank Kee, Aziz Sheikh, Shamim Rahman, Jonathan Valabhji, Ewen M. Harrison, Peter Sellen, Nazmus Haq, Malcolm G. Semple, Peter W.M. Johnson, Andrew Hayward and Jonathan S. Nguyen-Van-Tam
Type: Article | 2021

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology - Yanling Hu, Gemma Louise Fryatt, Mohammadmersad Ghorbani, Juliane Obst, David Menassa, Maria Martin estebane, Tim Arno Othni Muntslag, Adrian Olmos alonso, Monica Guerrero Carrasco, Daniel Thomas, Mark Cragg and Diego Gomez-Nicola
Type: Article | 2021 | Item not available on this server.

Type: Review | 2021

Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study - Martin Hutchings, Rogier Mous, Michael Roost Clausen, Peter Johnson, Kim M Linton, Martine E D Chamuleau, David John Lewis, Anna Sureda Balari, David Cunningham, Roberto S Oliveri, Brian Elliott, Dena DeMarco, Ada Azaryan, Christopher Chiu, Tommy Li, Kuo-Mei Chen, Tahamtan Ahmadi and Pieternella J Lugtenburg
Type: Article | 2021

Kinetics of abacavir-induced remodelling of the major histocompatibility complex class I peptide repertoire - Patricia Illing, Andy van Hateren, Rachel Darley, Nathan Croft, Nicole Mifsud, Samuel King, Lyudmila Kostenko, Mandvi Bharadwaj, James McCluskey, Timothy Elliott and Anthony Purcell
Type: Article | 2021

Genomic analysis of response to neoadjuvant chemotherapy in esophageal adenocarcinoma - Fereshteh Izadi, Benjamin P. Sharpe, Stella P. Breininger, Maria Secrier, Jane Gibson, Robert C. Walker, Saqib Rahman, Ginny Devonshire, Megan A. Lloyd, Zoë S. Walters, Rebecca C. Fitzgerald, Matthew J.J. Rose-Zerilli and Tim J. Underwood
Type: Article | 2021

DIPG harbour alterations targetable by MEK inhibitors, with acquired resistance mechanisms overcome by combinatorial inhibition - Elisa Izquierdo, Diana De Carvalho, Alan Mackay, Sara Temelso, Jessica K.R. Boult, Giulia Pericol, Elisabet Fernandez, Molina Das, Valeria Molinari, Yura Grabovska, Rebecca F. Rogers, Maria Antonietta Ajmone-Cat, Paula Z. Proszek, Mark Stubbs, Sarita Depan, Patricia O’Hare, Lu Yu, Georgia Roumeliot, Jyoti S. Choudhary, Matthew Clarke, Amy R. Fairchild, Thomas S. Jacques, Richard G. Grundy, Lisa Howell, Susan Picton, Jenny Adamski, Shaun Wilson, Juliet Gray, Bassel Zebian, Lynley V. Marshall, Fernando Carceller, Jacques Grill, Maria Vinci, Simon P. Robinson, Michael Hubank, Darren Hargrave and Chris Jones
Type: Article | 2021

The (epi)genomic landscape of splenic marginal zone lymphoma: biological implications, clinical utility, and future questions - Carolina Jaramillo Oquendo, Carolina Jaramillo Oquendo, Helen Parker, David Oscier, Sarah Ennis, Jane Gibson and Jonathan Strefford
Type: Review | 2021

Sacral nerve stimulation versus the magnetic sphincter augmentation device for adult faecal incontinence: the SaFaRI RCT - David G Jayne, Annabelle E Williams, Neil Corrigan, Julie Croft, Alison Pullan, Vicky Napp, Rachel Kelly, David Meads, Armando Vargas-Palacios, Adam Martin, Claire Hulme, Steven R Brown, Karen Nugent, Jen Lodge, David Protheroe, Sushil Maslekar, Andrew Clarke, Pasha Nisar and Julia M Brown
Type: Article | 2021

Empty pelvis syndrome: a systematic review of reconstruction techniques and their associated complications - Yanika L. Johnson, Malcolm A. West, Laura E. Gould, Ioanna Drami, Corina Behrenbruch, Elaine M. Burns, Alexander H. Mirnezami and John T. Jenkins
Type: Review | 2021

A peptide: MHC based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors. - Salim Khakoo, Pauline E Rettman, Matthew Blunt, Rebecca Fulton, Andres Vallejo Pulido, Leidy Bastidas Legarda, Laura Espana-Serrano, Marta Polak, Aymen Al-Shamkhani and Christelle Retiere
Type: Article | 2021

Selective depletion of radiolabeled HER2-specific antibody for contrast improvement during PET - Priyanka Khare, Wei Sun, Sreevidhya Ramakrishnan, Rafal Swiercz, Guiyang Hao, Su-Tang Lo, Kien Nham, Xiankai Sun, R.J. Ober and E. Sally Ward
Type: Article | 2021

RT-LAMP has high accuracy for detecting SARS-CoV-2 in saliva and naso/oropharyngeal swabs from asymptomatic and symptomatic individuals - Stephen Kidd, Daniel Burns, Bryony Armson, Andrew D. Beggs, Emma L. A. Howson, Anthony Williams, Gemma Snell, Emma L. Wise, Alice Goring, Zoé Vincent-Mistiaen, Seden Grippon, Jason Sawyer, Claire Cassar, David Cross, Tom Lewis, Scott Reid, Samantha Rivers, Joe James, Paul Skinner, Ashley Banyard, Kerrie Davies, Anetta Ptasinska, Celina M. Whalley, Charlie Poxon, Andrew Bosworth, I. Michael Kidd, Alex G. Richter, Jane Burton, Hannah Love, Sarah Fouch, Claire Tillyer, Amy Sowood, Helen Patrick, Nathan Moore, Michael Andreou, Shailen Laxman, Nick Morant, Duncan Clark, Charlotte Walsh, Rebecca Houghton, Joel D Parker, Joanne Slater-Jefferies, Ian Brown, Zandra Deans, Deborah Porter, Nicholas J. Cortes, Keith Godfrey, Angela Douglas, Sue Hill and Veronica L. Fowler
Type: Other | 2021 | medRxiv | Item not available on this server.

Prevalence of metachronous contralateral mature ovarian teratoma: a systematic review - David Kiely, Carianne Lewis, Juliet Gray and Nigel Hall
Type: Article | 2021

Rapid microfluidic isolation of virally infected primary bronchial epithelial cells for single-cell RNA sequencing - Lucy M Kimbley, Rachel Parker, Maaike SA Jongen, John Holloway, Emily Swindle and Matthew Rose-Zerilli
Type: Article | 2021 | Item not available on this server.

THz spectroscopy of BSA in a surface-tension confined flow-cell - Nicholas T. Klokkou, David J. Rowe, Bethany M. Bowden, Neil P. Sessions, Jonathan J. West, James S. Wilkinson and Vasilis Apostolopoulos
Type: Conference or Workshop Item | 2021 | IEEE | Item not available on this server.

CD8+CD103+ tissue-resident memory T cells convey reduced protective immunity in cutaneous squamous cell carcinoma - Chester Lai, George Stewart Coltart, Andrew Shapanis, Conor Healy, Ahmad Alabdulkareem, Sara Selvendran, Jeffrey Theaker, Matthew Sommerlad, Matthew Rose-Zerilli, Aymen Al-Shamkhani and Eugene Healy
Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy - M Lechner, VH Schartinger, CD Steele, WL Nei, ML Ooft, L-M Schreiber, CP Pipinikas, G T-Y Chung, YY Chan, F Wu, K-F To, CM Tsang, W Pearce, D Morelli, M Philpott, L Masterson, R Ribhani, G Wells, C Bell, J Koller, S Delacuse, YL Yip, J Liu, CT Forde, MD Forster, A Jay, J Dudas, A Krapp, S Wan, C Uprimny, S Sprung, J Haybaeck, TR Fenton, K Chester, C Thirlwell, G Royle, Teresa Marafioti, R Gupta, SR Indrasari, C Herdini, MAM Slim, I Indrawati, L Sutton, R Fles, B Tang, J Yeong, A Jain, S Han, H Wang, KSH Loke, W He, R Xu, Hongtao Jin, Z Cheng, D Howard, PH Hwang, Q-T Le, JK Tay, RB West, SW Tsao, T Meyer, H Riechelmann, U Oppermann, H-J Delecuse, SW Willems, MLK Chua, P Busson, KW Lo, G Wollmann, N Pillay, B Vanhaesebroeck and VJ Lund
Type: Article | 2021 | Item not available on this server.

Type: Article | 2021

Antibody responses after SARS-CoV-2 vaccination in patients with lymphoma - Sean H. Lim, Nicola Campbell, Marina Johnson, Debora Joseph-Pietras, Graham P. Collins, Ann O'Callaghan, Christopher Fox, Matthew Ahearne, Peter W.M. Johnson, David Goldblatt and Andrew J. Davies
Type: Article | 2021 | Item not available on this server.

Large cell neuroendocrine lung carcinoma: consensus statement from The British Thoracic Oncology Group and the Association of Pulmonary Pathologists - Colin R Lindsay, Emily C Shaw, David A Moore, Doris Rassl, Mariam Jamal-Hanjani, Nicola Steele, Salma Naheed, Craig Dick, Fiona Taylor, Helen Adderley, Fiona Black, Yvonne Summers, Matt Evans, Alexandra Rice, Aurelie Fabre, William A Wallace, Siobhan Nicholson, Alex Haragan, Phillipe Taniere, Andrew G Nicholson, Gavin Laing, Judith Cave, Martin D Forster, Fiona Blackhall, John Gosney, Sanjay Popat and Keith M Kerr
Type: Review | 2021 | Item not available on this server.

PTH-36 identification & service evaluation of a primary sclerosing cholangitis cohort using natural language processing - Robert Livingstone, Hang Phan, Florina Borca, Srishti Sarkar, Moeed Minto, Annie Dixey, Razzi Qaisar, Janisha Patel, Matthew Stammers and Markus Gwiggner
Type: Meeting abstract | 2021 | Item not available on this server.

Type: Article | 2021

Oligomeric Aβ1-42 induces an AMD-like phenotype and accumulates in lysosomes to impair RPE function - Savannah A. Lynn, David A. Johnston, Jenny A. Scott, Rosie Munday, Roshni S. Desai, Eloise Keeling, Ruaridh Weaterton, Alexander Simpson, Dillon Davis, Thomas Freeman, David S. Chatelet, Anton Page, Angela J. Cree, Helena Lee, Tracey A. Newman, Andrew J. Lotery and J. Arjuna Ratnayaka
Type: Article | 2021

Type: Article | 2021

Comprehensive imaging characterization of colorectal liver metastases - Drew Maclean, Maria Tsakok, Fergus Gleeson, David J Breen, Robert Goldin, John Primrose, Adrian Harris and James Franklin
Type: Review | 2021

Type: Thesis | 2021 | University of Southampton

Type: Article | 2021

Type: Article | 2021

Oxaliplatin/capecitabine or carboplatin/paclitaxel-based preoperative chemoradiation for resectable oesophageal adenocarcinoma (NeoSCOPE): long-term results of a randomised controlled trial - Somnath Mukherjee, Christopher Hurt, Ganesh Radhakrishna, Sarah Gwynne, Andrew Bateman, Simon Gollins, Maria A. Hawkins, Joanne Canham, Heike I. Grabsch, Stephen Falk, Ricky A Sharma, Ruby Ray, Rajarshi Roy, Catrin Cox, Nick Maynard, Lisette Nixon, David J. Henderson-Smart, Timothy Maughan, Gareth O. Griffiths and Tom D.L. Crosby
Type: Article | 2021

Prognostic significance of FCGR2B expression for the response of DLBCL patients to rituximab or obinutuzumab treatment - Malgorzata Nowicka, Laura K. Hilton, Margaret Ashton-Key, Chantal E Hargreaves, Chern Lee, Russell Foxall, Matthew Carter, Stephen A. Beers, Kathleen N. Potter, Christopher R. Bolen, Christian Klein, Andrea Knapp, Farheen Mir, Matthew Rose-Zerilli, Cathy Burton, Wolfram Klapper, David W. Scott, Laurie H. Sehn, Umberto Vitolo, Maurizio Martelli, Marek Trněný, Christopher K. Rushton, Graham W. Slack, Pedro Farinah, Jonathan C. Strefford, Mikkel Z. Oestergaard, Ryan D. Morin and Mark Cragg
Type: Article | 2021 | Item availability restricted.

The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers - Rachel S. Owen, Sri H. Ramarathinam, Alistair Bailey, Annalisa Gastaldello, Kathryn Hussey, Paul J. Skipp, Anthony W. Purcell and Hannah V. Siddle
Type: Article | 2021

Mendelian randomisation study of smoking exposure in relation to breast cancer risk - Hanla A. Park, Sonja Neumeyer, Kyriaki Michailidou, Manjeet K. Bolla, Qin Wang, Thomas U. Ahearn and Joe Dennis
Type: Article | 2021 | Item not available on this server.

1-year cost-utility analysis of prostate artery embolization (PAE) versus transurethral resection of the prostate (TURP) in benign prostatic hyperplasia (BPH) - Nikisha Patel, Nathan Yung, Ganesh Vigneswaran, Laure de Preux, Drew Maclean, Mark Harris, Bhaskar Somani, Timothy Bryant, Nigel Hacking and Sachin Modi
Type: Article | 2021

Type: Article | 2021

Defining standards in colorectal optimisation: a Delphi study protocol to achieve international consensus on key standards for colorectal surgery prehabilitation - Iona Pearson, Sue Blackwell, Rebecca Fish, Sarah Daniels, Malcolm West, Nanette Mutrie, P Kelly, Stephen Knight, Nicola S Fearnhead and Susan Moug
Type: Article | 2021

T-cell dysfunction in chronic lymphocytic leukemia from an epigenetic perspective - Fleur S. Peters, Jonathan Strefford, Eric Eldering and Arnon P. Kater
Type: Review | 2021

Type: Article | 2021 | Item not available on this server.

Acute kidney injury in COVID‐19: Identification of risk factors and potential biomarkers of disease in a large UK cohort - Thomas Phillips, Matt Stammers, Gary Leggatt, Becky Bonfield, Simon Fraser, Kirsten Armstrong and Kristin Veighey
Type: Article | 2021 | Item not available on this server.

Sequential assessment of bowel function and anorectal physiology after anterior resection for cancer: a prospective cohort study - S A Pilkington, Rahul Bhome, Sally Gilbert, S Harris, Carl Richardson, T C Dudding, J S Knight, A T King, A H Mirnezami, N E Beck, P H Nichols and K P Nugent
Type: Article | 2021

An adaptive, biomarker-directed platform study of durvalumab in combination with targeted therapies in advanced urothelial cancer - Thomas Powles, Danielle Carroll, Simon Chowdhury, Gwenaelle Gravis, Florence Joly, Joan Carles, Aude Fléchon, Pablo Maroto, Daniel Petrylak, Frédéric Rolland, Natalie Cook, Arjun V Balar, Srikala S Sridhar, Matthew D Galsky, Petros Grivas, Alain Ravaud, Robert Jones, Jan Cosaert, Darren Hodgson, Iwanka Kozarewa, Richard Mather, Robert McEwen, Florence Mercier and Dónal Landers
Type: Article | 2021 | Item availability restricted.

Restoration of T cell effector function, depletion of Tregs, and direct killing of tumor cells: The multiple mechanisms of action of a-TIGIT antagonist antibodies - Julie Preillon, Julia Cuende, Virginie Rabolli, Lucile Garnero, Marjorie Mercier, Noémie Wald, Angela Pappalardo, Sofie Denies, Diane Jamart, Anne-catherine Michaux, Romain Pirson, Vincent Pitard, Martine Bagot, Shruthi Prasad, Erica Houthuys, Margreet Brouwer, Reece Marillier, Florence Lambolez, Joäo R. Marchante, Florence Nyawouame, Mathew J. Carter, Véronique Baron-bodo, Anne Marie-cardine, Mark Cragg, Julie Déchanet-merville, Gregory Driessens and Catherine Hoofd
Type: Article | 2021

Type: Article | 2021

Type: Article | 2021

Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia - Miguel Quijada‐álamo, Claudia Pérez‐carretero, María Hernández‐sánchez, Ana‐eugenia Rodríguez‐vicente, Ana‐belén Herrero, Jesús‐maría Hernández‐sánchez, Marta Martín‐izquierdo, Sandra Santos‐mínguez, Mónica Del Rey, Teresa González, Araceli Rubio‐martínez, Alfonso García De Coca, Julio Dávila‐valls, José‐ángel Hernández‐rivas, Helen Parker, Jonathan C. Strefford, Rocío Benito, José‐luis Ordóñez and Jesús‐maría Hernández‐rivas
Type: Article | 2021

Type: Meeting abstract | 2021 | Item not available on this server.

Type: Meeting abstract | 2021 | Item not available on this server.

Type: Article | 2021 | Item not available on this server.

Type: Meeting abstract | 2021 | Item not available on this server.

Type: Article | 2021

The impact of postoperative chemotherapy on survival for oesophagogastric adenocarcinoma after preoperative chemotherapy and surgery - Saqib A Rahman, B. Thomas, Nick Maynard, M Park, H Wahedally, Nigel Trudgill, Tom Crosby, David Cromwell and Timothy Underwood
Type: Article | 2021

The AUGIS survival predictor: prediction of long-term and conditional survival after esophagectomy using Random Survival Forests - Saqib A Rahman, Robert C Walker, Nick Maynard, Nigel Trudgill, Tom Crosby, David Cromwell and Timothy Underwood
Type: Article | 2021

O69 outcome of direct access IBD physician delivered endoscopy for general practice referrals with suspected IBD - Sohail Rahmany, Matt Stammers, Louise Downey, Trevor Smith, Richard Felwick, Fraser Cummings and Markus Gwiggner
Type: Meeting abstract | 2021 | Item not available on this server.

Chromosome banding analysis and genomic microarrays are both useful but not equivalent methods for genomic complexity risk stratification in chronic lymphocytic leukemia patients - Silvia Ramos-campoy, Anna Puiggros, Sílvia Beà, Sandrine Bougeon, María José Larráyoz, Dolors Costa, Helen Parker, Gian Matteo Rigolin, Margarita Ortega, María Laura Blanco, Rosa Collado, Rocío Salgado, Tycho Baumann, Eva Gimeno, Carolina Moreno, Francesc Bosch, Xavier Calvo, María José Calasanz, Antonio Cuneo, Jonathan C. Strefford, Florence Nguyen-khac, David Oscier, Claudia Haferlach, Jacqueline Schoumans and Blanca Espinet
Type: Article | 2021

Disparity in peripheral and renal B-cell depletion with rituximab in systemic lupus erythematosus: an opportunity for obinutuzumab - Venkat R. Reddy, Ruth J. Pepper, Kavina Shah, Geraldine Cambridge, Scott R. Henerson, Christian Klein, Loren Kell, Samuel J. Taylor, David A. Isenberg, Mark Cragg and Maria J. Leandro
Type: Article | 2021 | Item availability restricted.

Type: Book | 2021 | University of Southampton

Type: Article | 2021

Type: Article | 2021

Type: Article | 2021 | Item not available on this server.

Best-BRA (Is subpectoral or prepectoral implant placement best in immediate breast reconstruction?): a protocol for a pilot randomised controlled trial of subpectoral versus prepectoral immediate implant-based breast reconstruction in women following mastectomy - Kirsty Roberts, Nicola Mills, Chris Metcalfe, Athene Lane, Clare Clement, William Hollingworth, Jodi Taylor, Chris Holcombe, Joanna Skillman, Katherine Fairhurst, Lisa Whisker, Ramsey Cutress, Steven Thrush, Patricia Fairbrother and Shelley Potter
Type: Article | 2021

The hydropathy index of the HCDR3 region of the B-Cell receptor identifies two subgroups of IGHV-mutated chronic lymphocytic leukemia patients with distinct outcome - Arancha Rodríguez-Caballero, Blanca Fuentes Herrero, Guillermo Oliva Ariza, Ignacio Criado, Miguel Alcoceba, Carlos Prieto, María Pérez Caro, Andrés C García-Montero, Marcos González Díaz, Francesco Forconi, Ana Bela Sarmento-Ribeiro, Julia Almeida and Alberto Orfao
Type: Article | 2021

3D super-resolution fluorescence microscopy maps the variable molecular architecture of the Nuclear Pore Complex - V.J. Sabinina, M.J. Hossain, J.K. Hériché, P. Hoess, B. Nijmeijer, S. Mosalaganti, M. Kueblbeck, A. Callegari, A. Szymborska, M. Beck, J. Ries and J. Ellenberg
Type: Article | 2021 | Item not available on this server.

Multiphasic prehabilitation across the cancer continuum: a narrative review and conceptual framework - Daniel Santa Mina, Stefanus J. Van Rooijen, Enrico M. Minnella, Shabbir M. H. Alibhai, Priya Brahmbhatt, Susanne O. Dalton, Chelsia Gillis, Michael P. W. Grocott, Doris Howell, Ian M. Randall, Catherine M. Sabiston, Julie K. Silver, Gerrit Slooter, Malcolm West, Sandy Jack and Franco Carli
Type: Review | 2021

Tools for analysis and conditional deletion of subsets of sensory neurons - Sonia Santana-Varela, Yury Bogdanov, Samuel J. Gossage, Andrei L. Okorokov, Shengnan Li, Larissa de Clauser, Marta Alves-Simoes, Jane E. Sexton, Federico Iseppon and Ana P. Luiz
Type: Article | 2021

PTH-32 development of a novel electronic referral grading & triage system - Srishti Sarkar, Robert Livingstone, Florina Borca, Matthew Stammers and Markus Gwiggner
Type: Meeting abstract | 2021 | Item not available on this server.

Clinical significance of crown-like structures to trastuzumab response in patients with primary invasive HER2+ breast cancer - Constantinos Savva, Charles N. Birts, Stéphanie A. Laversin, Alicia Lefas, Jamie Krishnan, Aron Schapira, Margaret Ashton-Key, Max Crispin, Peter W. M. Johnson, Jeremy P. Blaydes, Ellen Copson, Ramsey I. Cutress and Stephen A. Beers
Type: Meeting abstract | 2021 | Item not available on this server.

Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes - Isabell Schneider, Marta de Ruijter-Villani, M. Julius Hossain, Utrecht University Utrecht Netherlands and Jan Ellenberg
Type: Article | 2021

Methodological advances in the discovery of novel neuroblastoma therapeutics - Miguel F. Segura, Aroa Soriano, Josep Roma, Olga Piskareva, Carlos Jimenez, Ariadna Boloix, Jamie I. Fletcher, Michelle Harber, Juliet Gray, Leonor Cerda-Alberich, Blanca Martinez de Las Heras, Adela Canete, Soledad Gallego and Lucas Moreno
Type: Article | 2021 | Item availability restricted.

Type: Article | 2021

Anti-CD20 monoclonal antibodies in Systemic Lupus Erythematosus - Kavina Shah, Mark Cragg, Maria Leandro and Venkat Reddy
Type: Review | 2021

Digital pathology and machine learning for prediction of response to neoadjuvant chemotherapy in oesophageal adenocarcinoma - B. Sharpe, S. Rahman, J. Early, G. Vigneswaran, J. Horne, B. Grace, J. West, Z. Walters, S. Ramchurn and T. Underwood
Type: Meeting abstract | 2021 | Item not available on this server.

Synergistic effect of non-neutralizing antibodies and interferon-gamma for cross-protection against influenza - Meito Shibuya, Shigeyuki Tamiya, Atsushi Kawai, Toshiro Hirai, Mark Cragg and Yasuno Yoshioka
Type: Article | 2021

Type: Dataset | 2021 | University of Southampton

Activation of GABA(A) receptors inhibits T cell proliferation - Emma L. Sparrow, Sonya James, Khiyam Hussain, Stephen Beers, Mark Cragg and Yury Bogdanov
Type: Article | 2021

The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer - Rahul Sreekumar, Hajir Al-Saihati, Muhammad Emaduddin, Karwan Moutasim, Massimiliano Mellone, Ashish Patel, Seval Kilic, Metin Cetin, Sule Erdemir, Marta Salgado Navio, Maria Antonette Lopez, Nathan Curtis, Tamer Yagci, John N Primrose, Brendan D. Price, Geert Berx, Gareth J. Thomas, Eugene Tulchinsky, Alex Mirnezami and A. Emre Sayan
Type: Article | 2021

Type: Meeting abstract | 2021 | Item not available on this server.

Trifluridine/Tipiracil in metastatic colorectal cancer: A UK multicenter real-world analysis on efficacy, safety, predictive and prognostic factors - Chara Stavraka, Athanasios Pouptsis, Alicja Synowiec, Vasileios Angelis, Liyana Satterthwaite, Sam Khan, Meera Chauhan, Chloe Holden, Sally Young, Christina Karampera, Maria Martinou, Tina Mills-Baldock, Mark Baxter, Ainsley Barry, Bryony Eccles, Timothy Iveson, Kai-Keen Shiu, Mark Hill, Sherif Abdel-Raouf, Janet Shirley Graham, Anne Thomas and Paul J Ross
Type: Article | 2021 | Item not available on this server.

Exploring the pathways to chronic lymphocytic leukemia - Freda Stevenson, Francesco Forconi and Thomas J Kipps
Type: Article | 2021

Type: Article | 2021

Single-nucleotide Fcγ receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma - Jonathan Strefford, Mark Cragg, Andrew Davies, Helen Parker and Matthew Rose-Zerilli
Type: Article | 2021 | Item availability restricted.

Young women’s and midwives’ perspectives on improving nutritional support in pregnancy: the Babies, Eating and LifestyLe in Adolescence (BELLA) Study - Sofia Strommer, Susie Weller, Leanne Morrison, Hora Soltani, Judith Stephenson, Melissa Whitworth, Rachel Rundle, Jane Brewin, Lucilla Poston, Wendy Lawrence and Mary Barker
Type: Article | 2021

Protective low avidity anti-tumour CD8+ T cells are selectively attenuated by regulatory T cells - Gessa Sugiyarto, David Prossor, Eliuth David Arcia Anaya, Timothy Elliott and Edward James
Type: Article | 2021 | Item not available on this server.

Analysis of immune landscape in pancreatic and ileal neuroendocrine tumours demonstrates an immune cold tumour microenvironment - Lulu Tanno, Salma Naheed, Jonathan Dunbar, Jo Tod, Maria A Lopez, Julian Taylor, Maria Machado, Bryan Green, Margaret Ashton-Key, Serena J Chee, Oliver Wood, Neil W Pearce, Gareth J Thomas, Peter S Friedmann, Judith Cave and Christian H Ottensmeier
Type: Article | 2021 | Item not available on this server.

Translating employee-driven innovation in healthcare: bricolage and the mobilization of scarce resources - Rebecca Taylor, Alison Fuller, Susan Halford, Kate Lyle and Ann Charlotte Teglborg
Type: Article | 2021

Synthesis of carboxamide-containing tranylcypromine analogues as LSD1 (KDM1A) inhibitors targeting acute myeloid leukemia - Maria Teresa Borrello, Hanae Benelkebir, Adam Lee, Chak Hin Tam, Manar Shafat, Stuart A. Rushworth, Kristian M. Bowles, Leon Douglas, Patrick J. Duriez, Sarah Bailey, Simon J. Crabb, Graham Packham and A. Ganesan
Type: Article | 2021 | Item not available on this server.

DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity - Beatriz Valle-Argos, Giorgia Chiodin, Dean Bryant, Joe Taylor, Elizabeth Lemm, Patrick Duriez, Philip J Rock, Jonathan Strefford, Francesco Forconi, Richard Burack, Graham Packham and Freda Stevenson
Type: Article | 2021 | Item not available on this server.

Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering - Andres F. Vallejo, James Davies, Amit Grover, Ching-hsuan Tsai, Robert Jepras, Marta E. Polak and Jonathan West
Type: Article | 2021

Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution - Subramanian Vankatesan, Mihaela Angelova, Clare Puttick, Haoran Zhai, Deborah Caswell, Wei-Ting Lu, Michelle Dietzen, Panagiotis Galanos, Konstantinos Evangelou, Roberto Bellelli, Emilia L Lim, Thomas B K Watkins, Andrew Rowan, Vitor H Teixeira, Yue Zhao, Haiquan Chen, Bryan Ngo, Lykourgos-Panagiotis Zalmas, Maise Al Bakir, Sebastijan Hobor, Eva Gronroos, Adam Pennycuick, Ersilia Nigro, Brittany B Campbell, William L Brown, Ayse U Akarca, Teresa Marafioti, Mary Y Wu, Michael Howell, Simon J Boulton, Cosetta Bertoli, Tim R. Fenton, Robertus A M de Bruin, Apolinar Maya-Mendoza, Eric Santoni-Rugiu, Robert E Hynds, Vassilis G Gorgoulis, Mariam Jamal-Hanjani, Nicholas McGranahan, Reuben S Harris, Sam M Janes, Jirina Bartkova, Samuel F Bakhoum, Jiri Bartek, Nnennaya Kanu and Charles Swanton
Type: Article | 2021 | Item not available on this server.

Type: Article | 2021

Role for the histone demethylase KDM4B in rhabdomyosarcoma via CDK6 and CCNA2: compensation by KDM4A and Apoptotic Response of Targeting Both KDM4B and KDM4A - Zoë S Walters, Ewa Aladowicz, Barbara Villarejo-Balcells, Gary Nugent, Joanna L Selfe, Paul Eve, Julian Blagg, Olivia Rossanese and Janet Shipley
Type: Article | 2021

Type: Article | 2021

How best do we engage the general population in testing for COVID-19? - Daniella Watson, Natalia Laverty Baralle, Jawahr Alagil, Krithika Anil, Sandy Ciccognani, Rachel Dewar-Haggart, Sarah Fearn, Julia Groot, Kathryn Knowles, Claire Meagher, Carmel McGrath, Sarah Muir, Jo Musgrove, Kate Glyn-Owen, Kath Woods-Townsend, Andrew Mortimore, Paul Roderick, Janis Baird, Hazel Inskip, Keith Godfrey and Mary Barker
Type: UNSPECIFIED | 2021 | medRxiv

Type: Book Section | 2021 | Octaedro | Item not available on this server.

Droplet microfluidics with reagent micromixing for investigating intrinsic platelet functionality - Jonathan West, Maaike Sybilla Anna Jongen, Paul M Holloway, Simon I.R. Lane, Nicola Englyst and Owen McCarty
Type: Article | 2021

Type: Article | 2021

The effects of cancer therapies on physical fitness before oesophagogastric cancer surgery: a prospective, blinded, multi-centre, observational, cohort study [version 1; peer review: 2 approved] - Malcolm A. West, Zachos Anastasiou, Gareth Ambler, Lisa Loughney, Michael G. Mythen, Thomas Owen, Gerard Danjoux, Denny Z.H. Levett, Jamie J. Kelly, Sandy Jack and Michael P.W. Grocott
Type: Article | 2021

Cardiopulmonary exercise testing has greater prognostic value than sarcopenia in oesophago-gastric cancer patients undergoing neoadjuvant therapy and surgical resection - Malcolm A. West, William Ca Baker, Saqib Rahman, Alicia Munro, Sandra Jack, Michael Pw Grocott, Timothy J. Underwood, Denny Zh Levett and Stephen Wootton
Type: Article | 2021

Prehabilitation before surgery: is it for all patients? - Malcolm A. West, Sandy Jack and Michael P.w. Grocott
Type: Article | 2021

IgG regulation through FcRn blocking: A novel mechanism for the treatment of myasthenia gravis - Gil I. Wolfe, E. Sally Ward, Hans de Haard, Peter Ulrichts, Tahseen Mozattar, Mamatha Pasnoor and Gastur Vidarsson
Type: Review | 2021

Efficacy of platinum rechallenge in metastatic urothelial carcinoma after previous platinum-based chemotherapy for metastatic disease - Risa L. Wong, Lorin A. Ferris, Olivia A. Do, Sarah K. Holt, Jorge D. Ramos, Simon J. Crabb, Cora N. Sternberg, Joaquim Bellmunt, Sylvain Ladoire, Ugo De Giorgi, Lauren C. Harshman, Ulka N. Vaishampayan, Andrea Necchi, Sandy Srinivas, Sumanta K. Pal, Guenter Niegisch, Tanya B. Dorff, Matthew D. Galsky and Evan Y. Yu
Type: Article | 2021

Enrichment of Skeletal Stem Cells from Human Bone Marrow Using Spherical Nucleic Acids - Miguel Xavier, Maria-Eleni Kyriazi, Stuart Lanham, Konstantina Alexaki, Elloise Matthews, Afaf H El-Sagheer, Tom Brown, Antonios Kanaras and Richard Oreffo
Type: Article | 2021

Type: Dataset | 2021 | University of Southampton

Type: Letter | 2021

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