Items where Division is "Faculties (pre 2018 reorg) > Faculty of Medicine (pre 2018 reorg) > Cancer Sciences (pre 2018 reorg)" and Year is 2018
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Number of items: 139.
Type: Article
| 2018
The Southampton Consensus Guidelines for laparoscopic liver surgery: from indication to implementation - Mohammad Abu Hilal, Luca Aldrighetti, Ibrahim Dagher, Bjorn Edwin, Roberto Ivan Troisi, Ruslan Alikhanov, Somaiah Aroori, Giulio Belli, Marc Besselink, Javier Briceno, Brice Gayet, Mathieu D'Hondt, Mickael Lesurtel, Krishna Menon, Peter Lodge, Fernando Rotellar, Julio Santoyo, Olivier Scatton, Olivier Soubrane, Robert Sutcliffe, Ronald Van Dam, Steve White, Mark Christopher Halls, Federica Cipriani, Marcel Van der Poel, Ruben Ciria, Leonid Barkhatov, Yrene Gomez-Luque, Sira Ocana-Garcia, Andrew Cook, Joseph Buell, Pierre-Alain Clavien, Christos Dervenis, Giuseppe Fusai, David Geller, Hauke Lang, John Primrose, Mark Taylor, Thomas Van Gulik, Go Wakabayashi, Horacio Asbun and Daniel Cherqui
Type: Article
| 2018
IGF and IGFBP as an index for discrimination between vitamin D supplementation responders and nonresponders in overweight Saudi subjects - Nasser M. Al-Daghri, Sobhy M. Yakout, Kaiser Wani, Malak Nawaz Khan Khattak, Spiro D. Garbis, George P. Chrousos, Omar S. Al-Attas and Majed S. Alokail
Type: Article
| 2018
Subclonal evolution of cancer-related gene mutations in p53 immunopositive patches in human skin - Amel Albibas, Matthew Rose-Zerilli, Chester Lai, Reuben J Pengelly, Gabrielle Lockett, Jeffery Theaker, Sarah Ennis, John Holloway and Eugene Healy
Type: Article
| 2018
Type: Dataset
| 2018
| Elsevier
Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model - Alexandra J. Allen, Chuan Wang, Lisa J. Caproni, Gessa Sugiyarto, Elena L. Harden, Leon R. Douglas, Patrick J. Duriez, Kinga Karbowniczek, Jon Extance, Paul J. Rothwell, Ifeayinwa Orefo, John P. Tite, Freda K. Stevenson, Christian H. Ottensmeier and Natalia Savelyeva
Type: Article
| 2018
Structure of the recombinant Neisseria gonorrhoeae adhesin complex protein (rNg-ACP) and generation of murine antibodies with bactericidal activity against gonococci - Hannia, Liliana Almonacid Mendoza, Maria Humbert, Aiste Dijokaite, David Cleary, Yiwen Soo, Miao-chiu Hung, Christian M. Orr, Ivo Tews and Moritz M. Machelett
Type: Article
| 2018
Development of a core outcome set for clinical effectiveness trials in esophageal cancer resection surgery - Kerry N. L. Avery, Katy A. Chalmers, Sara T. Brookes, Natalie S. Blencowe, Karen Coulman, Katie Whale, Chris Metcalfe and Jame M. Blazeby
Type: Article
| 2018
Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors - Pelin Balcik-Ercin, Metin Cetin, Irem Yalin-Camci, Gorkem Odabas, Nurettin Toktay, Abdulkadir Sayan and Tamer Yagci
Type: Article
| 2018
The lived experience of Silver-Russell syndrome: implications for management during childhood and into adulthood - Lisa Ballard, Elizabeth Jenkinson, Christopher Byrne, Jenny Child, Justin Davies, Hazel Inskip, Oluwakemi Lokulo-Sodipe, Deborah Mackay, Emma L. Wakeling, Isabel Temple and Angela Fenwick
Type: Article
| 2018
Impact of contemporary patterns of chemotherapy utilization on survival in patients with advanced cancer of the urinary tract: a retrospective international study of invasive/advanced cancer of the urothelium (RISC) - A. Bamias, K. Tzannis, L.C. Harshman, S.J. Crabb, Y.-N. Wong, S. Kumar Pal, U. De Giorgi, S. Ladoire, N. Agarwal, E.Y. Yu, G. Niegisch, A. Necchi, C.N. Sternberg, S. Srinivas, A. Alva, U. Vaishampayan, L. Cerbone, M. Liontos, J. Rosenberg, T. Powles, J. Belmunt and M.D. Galsky
Type: Article
| 2018
Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations - Elizabeth K. Bancroft, Sibel Saya, Elizabeth C. Page, Kathryn Myhill, Sarah Thomas, Jennifer Pope, Anthony Chamberlain, Rachel Hart, Wayne Glover, Jackie Cook, Derek J. Rosario, Brian T. Helfand, Christina Hutten Selkirk, Rosemarie Davidson, Mark Longmuir, Diana M. Eccles, Neus Gadea, Carole Brewer, Julian Barwell, Monica Salinas, Lynn Greenhalgh, Marc Tischkowitz, Alex Henderson, David Gareth Evans, Saundra S. Buys, Rosalind A. Eeles and Neil K. Aaronson
Type: Article
| 2018
The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells - Arindam Banerjee, Pardis Arvinrad, Matthew Darley, Stephanie A Laversin, Rachel Parker, Matthew Rose-Zerilli, Paul A. Townsend, Ramsey Cutress, Stephen Beers, Franchesca D Houghton, Charles Birts and Jeremy Blaydes
Type: Article
| 2018
All that glitters is not gold - new reconstruction methods using Deauville criteria for patient reporting - Sally F. Barrington, Tom Sulkin, Adam Forbes and Peter W.M. Johnson
Type: Letter
| 2018
| Item not available on this server.
The Tyneside Pegboard Test: development, validation, and observations in unilateral cerebral palsy - Anna Basu, Emma V. Kirkpatrick, Blythe Wright, Janice E. Pearse, Kate E. Best and Janet A. Eyre
Type: Article
| 2018
Exosomal microRNAs (exomiRs): small molecules with a big role in cancer - Rahul Bhome, Filippo Del Vecchio, Gui-Han Lee, Marc D Bullock, John N Primrose, A Emre Sayan and Alex H Mirnezami
Type: Article
| 2018
Clinical relevance, prognostic potential, and therapeutic strategies of noncoding RNAs in cancer - Rahul Bhome, Louise House, Katherine Emo, Abdulkadir Sayan and Alex Mirnezami
Type: Book Section
| 2018
| Academic Press
| Item not available on this server.
The colorectal cancer microenvironment: strategies for studying the role of cancer-associated fibroblasts - Rahul Bhome, Massimiliano Mellone, Katherine Emo, Gareth J. Thomas, A. Emre Sayan and Alex H. Mirnezami
Type: Book Section
| 2018
| Humana New York
| Item not available on this server.
Development of an RNA-based kit for easy generation of TCR-engineered lymphocytes to control T-cell assay performance - Nicole Bidmon, Sonja Kind, Marij J.P. Welters, Deborah Joseph-Pietras, Karoline Laske, Dominik Maurer, Sine Reker Hadrup, Gerty Schreibelt, Richard Rae, Ugur Sahin, Cécile Gouttefangeas, Cedrik M. Britten and Sjoerd H. van der Burg
Type: Article
| 2018
Delta-like ligand-4-notch signaling inhibition regulates pancreatic islet function and insulin secretion - Fabienne Billard, Katia P. Karalis, Sevasti Karaliota, Bei Wing, Dimitrios Stellas, Ioannis Serafimidis, Antigoni Manousopoulou, Yiassemi Koutmani, Elpiniki Ninou, Jacquelynn Golubov, Amanda DaNave, Panagiotis Tsakanikas, Yurong Xin, Wen Zhang, Matthew Sleeman, George D. Yancopoulos, Andrew Murphy, Spiros D. Garbis, Katia P. Karalis and Dimitris Skokos
Type: Article
| 2018
A mechanistic model for predicting cell surface presentation of competing peptides by MHC class I molecules - Denise S. M. Boulanger, Ruth C. Eccleston, Andrew Phillips, Peter V. Coveney, Timothy Elliott and Neil Dalchau
Type: Article
| 2018
Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia - Laurie Freire Boullosa, Payalben Savaliya, Stephanie Bonney, Laurence Orchard, Hannah Wickenden, Cindy Lee, Evelien Smits, Alison H. Banham, Ken I. Mills, Kim Orchard and Barbara Ann Guinn
Type: Article
| 2018
Impact of question order on prioritisation of outcomes in the development of a core outcome set: A randomised controlled trial - Sara T. Brookes, Katy A. Chalmers, Kerry N.L. Avery, Karen Coulman, Jane M. Blazeby, Derek Alderson, John Whiting, Bilal Alkhaffaf, William Allum, Stephen Attwood, Hugh Barr, David Hewin, Simon Higgs, Mark Vipond, Issy Batiwalla, Guy Blackshaw, Marilyn Bolter, Claire Goulding, Richard Berrisford, Grant Sanders, Tim Wheatley, Abrie Botha, Robert Mason, Jim Byrne, Jamie Kelly, Joanne Callan, Graeme Couper, Chris Deans, Simon Paterson-Brown, Khaled Dawas, Muntzer Mughal, Simon Galloway, Michelle George, Jay Gokhale, Mike Goodman, Richard Hardwick, Ahmed Hassn, Mark Henwood, Richard Kryzstopik, Michael Lewis, Jane Tallett, Colin MacKay, James Manson, Ruth Moxon, Sue Osborne, Richard Page, Mike Shackcloth, Raj Parameswaran, Simon Parsons and Tim Underwood
Type: Article
| 2018
| Item not available on this server.
Hypercalcaemia secondary to ectopic parathyroid hormone expression in an adolescent with metastatic alveolar rhabdomyosarcoma - Rachael Brooks, Christopher Lord, Justin H. Davies and Juliet C. Gray
Type: Article
| 2018
| Item not available on this server.
Antibodies to costimulatory receptor 4-1BB enhance anti-tumor immunity via T regulatory cell depletion and promotion of CD8 T cell effector function - Sarah Buchan, Lang Dou, Marcus Remer, Steven Booth, Stuart N Dunn, Chester Lai, Monika Semmrich, Ingrid Teige, Linda Martensson, Christine Penfold, H.T. Claude Chan, Jane Willoughby, C. Ian Mockridge, Lekh Dahal, Anne Rogel, Paivi Kannisto, Mats Jernetz, Emily L Williams, Eugene Healy, J. Sjef Verbeek, Peter Johnson, Bjorn Frendeus, Mark Cragg, Martin Glennie, Juliet Gray, Aymen Al-Shamkhani and Stephen Beers
Type: Article
| 2018
PD-1 blockade and CD27 stimulation activate distinct transcriptional programs that synergize for CD8+ T-cell driven anti-tumor immunity - Sarah Buchan, Mohannad Fallatah, Stephen Thirdborough, Vadim Y. Taraban, Anne Rogel, Lawrence J. Thomas, Christine Penfold, Li-Zhen He, Michael Curran, Tibor Keler and Aymen Al-Shamkhani
Type: Article
| 2018
The immunobiology of CD27 and OX40 and their potential as targets for cancer immunotherapy - Sarah Buchan, Anne Rogel and Aymen Al-Shamkhani
Type: Article
| 2018
Induction of amyloid-β42 production by fipronil and other pyrazole insecticides - Morgane Cam, Emilie Durieu, Marion Bodin, Antigoni Manousopoulou, Svenja Koslowski, Natalia Vasylieva, Bogdan Barnych, Bruce D. Hammock, Rebecca L. McMahen, Mark J. Strynar, Bettina Bohl, Philipp Koch, Chiori Omori, Kazuo Yamamoto, Saori Hata, Toshiharu Suzuki, Frank Karg, Patrick Gizzi, Vesna Erakovic-Haber, Vlatka Bencetic Mihaeljevic, Branka Tavcar, Erik Portelius, Josef Pannee, Kaj Blennow, Henrik Zetterberg, Spiros Garbis, Pierrick Auvray, Hermeto Gerber, Jeremy Fraering, Patrick Fraering and Laurent Meijer
Type: Article
| 2018
Pan-cancer deconvolution of tumour composition using DNA methylation - Ankur Chakravarthy, Andrew Furness, Kroopa Joshi, Ehsan Ghorani, Kirsty Ford, Matthew J. Ward, Emma V. King, Matt Lechner, Teresa Marafioti, Sergio A. Quezada, Gareth J Thomas, Andrew Feber and Tim Fenton
Type: Article
| 2018
Erratum to: Pan-cancer deconvolution of tumour composition using DNA methylation (Nature Communications, (2018), 9, 1, (3220), 10.1038/s41467-018-05570-1) - Ankur Chakravarthy, Andrew Furness, Kroopa Joshi, Ehsan Ghorani, Kirsty Ford, Matthew J. Ward, Emma V. King, Matt Lechner, Teresa Marafioti, Sergio A. Quezada, Gareth J. Thomas, Andrew Feber and Tim R. Fenton
Type: Letter
| 2018
Novel biomarkers for patient stratification in colorectal cancer: A review of definitions, emerging concepts, and data - Manish Chand, Deborah S. Keller, Reza Mirnezami, Marc Bullock, Aneel Bhangu, Brendan Moran, Paris P. Tekkis, Gina Brown, Alex Mirnezami and Mariana Berho
Type: Review
| 2018
Validation of immunomonitoring methods for application in clinical studies: the HLA-peptide multimer staining assay - P. Anoop Chandran, Karoline Laske, Angelica Cazaly, Elisa Rusch, Barbara Schmid-Horch, Hans Georg Rammensee, Christian H. Ottensmeier and Cécile Gouttefangeas
Type: Article
| 2018
| Item not available on this server.
Addressing modifiable risk factors in symptomatic breast clinics: The Abreast of Health Study alcohol risk profiles - Ellen Copson, Peter Dutey-Magni, Caspian Priest, Ramsey Cutress, Annie Anderson, Mark McCann, Janice Baird, Mary Barker, Eileen F.S. Kaner and Julia Sinclair
Type: Article
| 2018
| Item not available on this server.
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): A prospective cohort study - Ellen R. Copson, Tom C. Maishman, Will J. Tapper, Ramsey I. Cutress, Stephanie Greville-Heygate, Douglas G. Altman, Bryony Eccles, Sue Gerty, Lorraine Durcan, Louise Jones, D.Gareth Evans, Alastair M. Thompson, Paul Pharoah, Douglas F. Easton, Alison M. Dunning, Andrew Hanby, Sunil R. Lakhani, Ros Eeles, Fiona J. Gilbert, Hisham Hamed, Shirley Hodgeson, Peter Simmonds, Louise Stanton and Diana Eccles
Type: Article
| 2018
Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial - P.G. Corrie, P.D. Nathan, P. Lorigan, S. Tahir, G. Faust, C.G. Kelly, M. Marples, S.J. Danson, E. Marshall, S.J. Houston, R.E. Board, A.M. Waterston, J.P. Nobes, M. Harries, S. Kumar, A. Goodman, A. Dalgleish, A. Martin-Clavijo, S. Westwell, R. Casasola, D. Chao, A. Maraveyas, P.M. Patel, C.H. Ottensmeier, D. Farrugia, A. Humphreys, B. Eccles, G. Young, E.O. Barker, C. Harman, M. Weiss, K.A. Myers, A. Chhabra, S.H. Rodwell, J.A. Dunn and M.R. Middleton
Type: Article
| 2018
Therapeutic discovery for castration resistant prostate cancer: patient-derived xenograft modelling brings new options to the table - Simon J. Crabb
Type: Editorial
| 2018
Mutation screening using formalin-fixed paraffin-embedded tissues: a stratified approach according to DNA quality - Francesco Cucco, Alexandra Clipson, Hannah Kennedy, Joe Sneath Thompson, Ming Wang, Sharon Barrans, Moniek van Hoppe, Eguzkine Ochoa Ruiz, Josh Caddy, Debbie Hamid, Thomas Cummin, Cathy Burton, Andrew J. Davies, Peter Johnson and Ming Qing Du
Type: Article
| 2018
Time from colorectal cancer diagnosis to laparoscopic curative surgery: is there a safe window for prehabilitation? - N. J. Curtis, M. A. West, E. Salib, J. Ockrim, A. S. Allison, R. Dalton and Nader K. Francis
Type: Article
| 2018
| Item availability restricted.
Opportunities and priorities for breast surgical research - Ramsey Cutress, Stuart A. McIntosh, Shelley Potter, Amit Goyal, Cliona C. Kirwan, James Harvey, Adele Francis, Amtul R. Carmichael, Raghaven Vidya, Jayant S. Vaidya, Patricia Fairbrother, John Benson and Malcolm W.R. Reed
Type: Review
| 2018
UC-1V150, a potent TLR7 agonist capable of activating macrophages and potentiating mAb-mediated target cell deletion - Lekh Dahal, Adam Gadd, Alexander Edwards, Mark Cragg and Stephen Beers
Type: Article
| 2018
Shaving is an epiphenomenon of Type i and II anti-CD20-mediated phagocytosis, whereas antigenic modulation limits type i monoclonal antibody efficacy - Lekh N. Dahal, Chie Yin Huang, Richard J. Stopforth, Abbie Mead, Keith Chan, Juliet X. Bowater, Martin C. Taylor, Priyanka Narang, H. T.Claude Chan, Jinny H. Kim, Andrew T. Vaughan, Francesco Forconi and Stephen A. Beers
Type: Article
| 2018
Through the barricades: overcoming the barriers to effective antibody-based cancer therapeutics - Martin Dalziel, Stephen Beers, Mark Cragg and Max Crispin
Type: Review
| 2018
A computational framework for complex disease stratification from multiple large-scale datasets - Bertrand De Meulder, Diane Lefaudeux, Aruna T. Bansal, Alexander Mazein, Amphun Chaiboonchoe, Hassan Ahmed, Irina Balaur, Mansoor Saqi, Johann Pellet, Stéphane Ballereau, Nathanaël Lemonnier, Kai Sun, Ioannis Pandis, Xian Yang, Manohara Batuwitage, Kosmas Kretsos, Jonathan van Eyll, Alun Bedding, Timothy Davison, Paul Dodson, Christopher Larminie, Anthony Postle, Julie Corfield, Ratko Djukanovic, Kian Fan Chung, Ian M. Adcock, Yi Ke Guo, Peter J. Sterk, Alexander Manta, Anthony Rowe, Frédéric Baribaud, Charles Auffray, David Gibeon, Uruj Hoda, Scott Kuo, Joost Brandsma, Dominic Burg, Patrick Dennison, Ben Nicholas, James P.R. Schofield, Paul J. Skipp, Doroteya Staykova, Kamran Tariq, Jonathan Ward, Susan J. Wilson, Clair Barber, Lorraine Hewitt, Peter Howarth, Graham Roberts and Kerry Gove
Type: Article
| 2018
Long non-coding RNAs within the tumour microenvironment and their role in tumour-stroma cross-talk - Filippo Del Vecchio, Gui Han Lee, Joamir Hawezi, Rahul Bhome, Sian Pugh, Emre Sayan, Gareth Thomas, Graham Packham, John Primrose, Martin Pichler, Alexander Mirnezami, George Calin and Marc Bullock
Type: Review
| 2018
Correction: 'Is this knowledge mine and nobody else's? i don't feel that.' Patient views about consent, confidentiality and information-sharing in genetic medicine (Journal of Medical Ethics (2016) 42 (174-179) DOI: 10.1136/medethics-2015-102781) - S. Dheensa, A. Fenwick and A. Lucassen
Type: Article
| 2018
| Item not available on this server.
Impact of tumour microenvironmental factors on B-cell signalling, migration and adhesion in chronic lymphocytic leukaemia - Rachel Colette Dobson
Type: Thesis
| 2018
| University of Southampton
Dimensions of responsibility in medical genetics: exploring the complexity of the “duty to recontact” - Shane Doheny, Angus Clarke, Daniele Carrieri, Sandi Dheensa, Naomi Hawkins, Anneke Lucassen, Peter Turnpenny and Susan Kelly
Type: Article
| 2018
Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study - Suzanne C. Dixon-Suen
Type: Article
| 2018
| Item availability restricted.
Genetic testing for young women with breast cancer – Authors' reply - Diana M. Eccles and Ellen R. Copson
Type: Letter
| 2018
| Item not available on this server.
Implications of tuberculosis reactivation after immune checkpoint inhibition - Paul Elkington, Adrian Bateman, Gareth Thomas and Christian Ottensmeier
Type: Letter
| 2018
Protein plasticity and peptide editing in the MHC I antigen processing pathway - Tim Elliott and Andrew Van Hateren
Type: Review
| 2018
Nrf2 deficiency unmasks the significance of nitric oxide synthase activity for cardioprotection - Ralf Erkens, Tatsiana Suvorava, Thomas R. Sutton, Bernadette O Fernandez, Monika Mikus-Lelinska, Frederik Barbarino, Ulrich Flögel, Malte Kelm, Martin Feelisch and Miriam M Cortese-Krott
Type: Article
| 2018
A dominantly inherited 5'UTR variant causing methylation associated silencing of BRCA1 as a cause of breast and ovarian cancer - D.Gareth R. Evans, Elke M. van Veen, Helen J. Byers, Andrew J. Wallace, Jamie M. Ellingford, Glenda Beaman, Javier Santoyo-Lopez, Timothy J. Aitman, Diana Eccles, Fiona I. Lalloo, Miriam J. Smith and William G. Newman
Type: Article
| 2018
CONFIRM: a double-blind, placebo-controlled phase III clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma: study protocol for a randomised controlled trial - Dean A. Fennell, Emma Kirkpatrick, Kelly Cozens, Mavis Nye, Jason Lester, Gerard Hanna, Nicola Steele, Peter Szlosarek, Sarah Danson, Joanne Lord, Christian Ottensmeier, Daniel Barnes, Stephanie Hill, Michail Kalevras, Thomas Maishman and Gareth Griffiths
Type: Article
| 2018
The road to clinical fantasy: a UK perspective - Angela Fenwick, Anneke Lucassen and Peta Coulson-Smith
Type: Article
| 2018
Cleavage of TL1A differentially regulates its effects on innate and adaptive immune cells - John R. Ferdinand, Arianne C. Richard, Françoise Meylan, Aymen Al-Shamkhani and Richard M. Siegel
Type: Article
| 2018
| Item availability restricted.
Five years of ibrutinib in CLL - Francesco Forconi
Type: Review
| 2018
| Item not available on this server.
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 - Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V Antonov, Eli Arama, Eric H Baehrecke, Nickolai A Barlev, Nicolas G Bazan, Francesca Bernassola, Mathieu J M Bertrand, Katiuscia Bianchi, Mikhail V Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona-Gutierrez, Francesco Cecconi, Francis K-M Chan, Navdeep S Chandel, Emily H Cheng, Jerry E Chipuk, John A Cidlowski, Aaron Ciechanover, Gerald M Cohen, Marcus Conrad, Juan R Cubillos-Ruiz, Peter E Czabotar, Vincenzo D'Angiolella, Ted M Dawson, Valina L Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus-Michael Debatin, Ralph J DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M Dixit, Scott J Dixon, Colin S Duckett, Brian D Dynlacht, Wafik S El-Deiry, John W Elrod, Gian Maria Fimia, Simone Fulda, Ana J García-Sáez, Abhishek D Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R Green, Lloyd A Greene, Hinrich Gronemeyer, Atan Gross, Gyorgy Hajnoczky, J Marie Hardwick, Isaac S Harris, Michael O Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J Jost, Philippe P Juin, William J Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N Kitsis, Daniel J Klionsky, Richard A Knight, Sharad Kumar, Sam W Lee, John J Lemasters, Beth Levine, Andreas Linkermann, Stuart A Lipton, Richard A Lockshin, Carlos López-Otín, Scott W Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic, Jean-Christophe Marine, Seamus J Martin, Jean-Claude Martinou, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Sonia Melino, Edward A Miao, Jeffery D Molkentin, Ute M Moll, Cristina Muñoz-Pinedo, Shigekazu Nagata, Gabriel Nuñez, Andrew Oberst, Moshe Oren, Michael Overholtzer, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef M Penninger, David M Pereira, Shazib Pervaiz, Marcus E Peter, Mauro Piacentini, Paolo Pinton, Jochen H M Prehn, Hamsa Puthalakath, Gabriel A Rabinovich, Markus Rehm, Rosario Rizzuto, Cecilia M P Rodrigues, David C Rubinsztein, Thomas Rudel, Kevin M Ryan, Emre Sayan, Luca Scorrano, Feng Shao, Yufang Shi, John Silke, Hans-Uwe Simon, Antonella Sistigu, Brent R Stockwell, Andreas Strasser, Gyorgy Szabadkai, Stephen W G Tait, Daolin Tang, Nektarios Tavernarakis, Andrew Thorburn, Yoshihide Tsujimoto, Boris Turk, Tom Vanden Berghe, Peter Vandenabeele, Matthew G Vander Heiden, Andreas Villunger, Herbert W Virgin, Karen H Vousden, Domagoj Vucic, Erwin F Wagner, Henning Walczak, David Wallach, Ying Wang, James A Wells, Will Wood, Junying Yuan, Zahra Zakeri, Boris Zhivotovsky, Laurence Zitvogel, Gerry Melino and Guido Kroemer
Type: Review
| 2018
PTBP1-Mediated alternative splicing regulates the inflammatory secretome and the pro-tumorigenic effects of senescent cells - Athena Georgilis, Sabrina Klotz, Christopher J. Hanley, Nicolas Herranz, Benedikt Weirich, Beatriz Morancho, Ana Carolina Leote, Luana D'Artista, Suchira Gallage, Marco Seehawer, Thomas Carroll, Gopuraja Dharmalingam, Keng Boon Wee, Marco Mellone, Joaquim Pombo, Danijela Heide, Ernesto Guccione, Joaquín Arribas, Nuno L. Barbosa-Morais, Mathias Heikenwalder, Gareth J. Thomas, Lars Zender and Jesús Gil
Type: Article
| 2018
PET-PANC: Multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-dglucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer - Paula Ghaneh, Robert Hanson, Andrew Titman, Gill Lancaster, Catrin Plumpton, Huw Lloyd-Williams, Seow Tien Yeo, Rhiannon Tudor Edwards, Colin Johnson, Mohammed Abu Hilal, Antony P. Higginson, Tom Armstrong, Andrew Smith, Andrew Scarsbrook, Colin McKay, Ross Carter, Robert P. Sutcliffe, Simon Bramhall, Hemant M. Kocher, David Cunningham, Stephen P. Pereira, Brian Davidson, David Chang, Saboor Khan, Ian Zealley, Debashis Sarker, Bilal Al Sarireh, Richard Charnley, Dileep Lobo, Marianne Nicolson, Christopher Halloran, Michael Raraty, Robert Sutton, Sobhan Vinjamuri, Jonathan Evans, Fiona Campbell, Jon Deeks, Bal Sanghera, Wai Lup Wong and John P. Neoptolemos
Type: Article
| 2018
| Item not available on this server.
Outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma and predictors of survival - Syeda Nadia Shah Gilani, Akash Mehta, Alfonso Garcia-Fadrique, Babatunde Rowaiye, Veronika Jenei, Sanjeev Dayal, Kandiah Chandrakumaran, Norman Carr, Faheez Mohamed, Tom Cecil and Brendan Moran
Type: Article
| 2018
| Item not available on this server.
Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study - Fabio Girardi, Daniel Barnes, Daniel Barrowdale, Debra Frost, Angela Brady, Claire Miller, Alan Donaldson, Alex Murray, Carole Brewer, Caroline Pottinger, Gareth Evans, Diana Eccles, Fiona Lalloo, Helen Gregory, Jackie Cook, Jacqueline Eason, Julian Adlard, Julian Barwell, Kai-Ren Ong, Lisa Walker, Louise Izatt, Lucy E. Side, M. John Kennedy, Marc Tischkowitz, Mark T. Rogers, Marc Tischkowitz, Mark T. Rogers, Mary E. Porteous, Patrick J. Morrison, Ros Eeles, Rosemarie Davidson, Katie Snape, Douglas F. Easton and Antonis C. Antoniou
Type: Article
| 2018
CHOP versus GEM-P in previously untreated patients with peripheral T-cell lymphoma (CHEMO-T): a phase 2, multicentre, randomised, open-label trial - Mary Gleeson, Clare Peckitt, Ye Mong To, Laurice Edwards, Jacqueline Oates, Andrew Wotherspoon, Ayoma D. Attygalle, Imene Zerizer, Bhupinder Sharma, Sue Chua, Ruwaida Begum, Ian Chau, Peter Johnson, Kirit M. Ardeshna, Eliza A. Hawkes, Marian P. Macheta, Graham P. Collins, John Radford, Adam Forbes, Alistair Hart, Silvia Montoto, Pamela McKay, Kim Benstead, Nicholas Morley, Nagesh Kalakonda, Yasmin Hasan, Deborah Turner and David Cunningham
Type: Article
| 2018
Type: Article
| 2018
| Item availability restricted.
Type: Book
| 2018
| Springer
| Item not available on this server.
A novel human pain insensitivity disorder caused by a point mutation in ZFHX2 - Abdella M. Habib, Ayako Matsuyama, Andrei L. Okorokov, Sonia Santana-Varela, Jose T. Bras, Anna Maria Aloisi, Edward C. Emery, Yury D Bogdanov, Maryne Follenfant, Sam J. Gossage, Mathilde Gras, Jack Humphrey, Anna Kolesnikov, Kim Le Cann, Shengnan Li, Michael S. Minett, Vanessa Pereira, Clara Ponsolles, Shafaq Sikandar, Jesus M. Torres, Kenji Yamaoka, Jing Zhao, Yuriko Komine, Tetsuo Yamamori, Nikolas Maniatis, Konstantin I Panov, Henry Houlden, Juan D. Ramirez, David L.H. Bennett, Letizia Marsili, Valeria Bachiocco, John N. Wood and James J. Cox
Type: Article
| 2018
Development and validation of a difficulty score to predict intraoperative complications during laparoscopic liver resection - M. C. Halls, G. Berardi, F. Cipriani, L. Barkhatov, P. Lainas, S. Harris, M. D'Hondt, F. Rotellar, I. Dagher, L. Aldrighetti, R. I. Troisi, B. Edwin and M. Abu Hilal
Type: Article
| 2018
Targeting the myofibroblastic cancer-associated fibroblast phenotype through inhibition of NOX4 - Christopher J. Hanley, Massimiliano Mellone, Kirsty Ford, Steve M. Thirdborough, Toby Mellows, Steven J. Frampton, David M. Smith, Elena Harden, Cedric Szyndralewiez, Marc Bullock, Fergus Noble, Karwan A. Moutasim, Emma V. King, Pandurangan Vijayanand, Alex H. Mirnezami, Timothy J. Underwood, Christian H. Ottensmeier and Gareth J. Thomas
Type: Article
| 2018
Early breast cancer: why does obesity affect prognosis? - Adam Heetun, Ramsey I. Cutress and Ellen R. Copson
Type: Review
| 2018
Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting - Paul M. Holloway, Jonathan Butement, Manjunath Hegde and Jonathan West
Type: Article
| 2018
E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium - Hisani N. Horne, Hannah Oh, Mark E. Sherman, Maya Palakal, Stephen M. Hewitt, Marjanka K. Schmidt, Roger L. Milne, David Hardisson, Javier Benitez, Carl Blomqvist, Manjeet K. Bolla, Hermann Brenner, Jenny Chang-claude, Renata Cora, Fergus J. Couch, Katarina Cuk, Peter Devilee, Douglas F. Easton, Diana M. Eccles, Ursula Eilber, Jaana M. Hartikainen, Päivi Heikkilä, Bernd Holleczek, Maartje J. Hooning, Michael Jones, Renske Keeman, Arto Mannermaa, John W.M. Martens, Taru A. Muranen, Heli Nevanlinna, Janet E. Olson, Nick Orr, Jose I.A. Perez, Paul D.P. Pharoah, Kathryn J. Ruddy, Kai-uwe Saum, Minouk J. Schoemaker, Caroline Seynaeve, Reijo Sironen, Vincent T.H.B.M. Smit, Anthony J. Swerdlow, Maria Tengström, Abigail S. Thomas, A. Mieke Timmermans, Rob A.E.M. Tollenaar, Melissa A. Troester, Christi J. van Asperen, Carolien H.M. Van Deurzen, Flora F. Van Leeuwen, Laura J. Van’t Veer, Montserrat García-closas and Jonine D. Figueroa
Type: Article
| 2018
Variable responses of MYC translocation positive lymphoma cell lines to different combinations of novel agents: Impact of BCL2 family protein expression - Peter Johnson, Wenhan Deng, Alexandra Clipson, Hongxiang Liu, Yuanxue Huang, Rachel Dobson, Ming Wang and Ming-Qing Du
Type: Article
| 2018
Proteomics profiling of CLL versus healthy B-cells identifies putative therapeutic targets and a subtype-independent signature of spliceosome dysregulation - Harvey Johnston, Matthew Carter, Marta Larrayoz, James, Ian Clarke, Spiros Garbis, David G Oscier, Jonathan Strefford, Andrew Steele, Renata Walewska and Mark Cragg
Type: Article
| 2018
Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis - Mark Jones, Orestis Andriotis, James Roberts, Alessandra Bonfanti, Peter Johnson, Franco Conforti, Chester Lai, Benjamin Johnson, Konstantinos Bourdakos, Benjamin Marshall, Christian Ottensmeier, Atul Bhaskar and Donna Davies
Type: Article
| 2018
The prognostic role of the change in neutrophil-to-lymphocyte ratio during neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer: A retrospective, multi-institutional sudy - Jeenan Kaiser, Haocheng Li, Scott A. North, Raya Leibowitz-Amit, Jo-An Seah, Nisha Morshed, Caroline Chau, Richard Lee-Ying, Daniel Y.C. Heng, Srikala Sridhar, Simon J. Crabb and Nimira S. Alimohamed
Type: Article
| 2018
Percutaneous hepatic perfusion with melphalan in uveal melanoma: a safe and effective treatment modality in an orphan disease - Ioannis Karydis, Alexandra Gangi, Matthew J Wheater, Junsung Choi, Iain Wilson, Kerry Thomas, Neil Pearce, Arjun Takhar, Sanjay Gupta, Danielle Hardman, Sean Sileno, Brian Stedman, Jonathan S Zager and Christian Ottensmeier
Type: Article
| 2018
Laparoscopic versus open major hepatectomy: a systematic review and meta-analysis of individual patient data - Meidai Kasai, Federica Cipriani, Brice Gayet, Luca Aldrighetti, Francesca Ratti, Juan M Sarmiento, Olivier Scatton, Ki-Hun Kim, Ibrahim Dagher, Baki Topal, John Primrose, Takeo Nomi, David Fuks and Mohammad Abu Hilal
Type: Review
| 2018
Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer - Sofia Khan, Rainer Fagerholm, Latha Kadalayil, William Tapper, Kristiina Aittomäki, Jianjun Liu, Carl Blomqvist, Diana Eccles and Heli Nevanlinna
Type: Article
| 2018
C-terminal binding proteins link glycolytic metabolism with the adaptive response to tumor hypoxia and pH regulation - Mira Kreuzer
Type: Thesis
| 2018
| University of Southampton
Type: Review
| 2018
Type: Thesis
| 2018
| University of Southampton
Type: Review
| 2018
Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity (ADCC), and complement dependent cytotoxicity (CDC) - Stefan Lohse, Sebastian Loew, Anna Kretschmer, J.H. Marco Jansen, Saskia Meyer, Toine Ten Broeke, Thies Rosner, Michael Dechant, Stefanie Derer, Katja Klausz, Christian Kellner, Ralf Schwanbeck, Ruth French, Thomas Tipton, Mark Cragg, Denis M. Schewe, Matthias Peipp, Jeanette Leusen and Thomas Valerius
Type: Article
| 2018
Towards a national genomics medicine service: the challenges facing clinical-research hybrid practices and the case of the 100,000 genomes project - Anneke Lucassen, Sandeep Dheensa, Gabrielle Samuel and Bobbie Farsides
Type: Article
| 2018
Alerting relatives about heritable risks: the limits of confidentiality - Anneke Lucassen and Roy Gilbar
Type: Article
| 2018
Increased SHISA3 expression characterizes chronic lymphocytic leukemia patients sensitive to lenalidomide - Rossana Maffei, Stefania Fiorcari, Silvia Martinelli, Stefania Benatti, Jenny Bulgarelli, Lara Rizzotto, Giulia Debbia, Rita Santachiara, Gian Matteo Rigolin, Francesco Forconi, Davide Rossi, Luca Laurenti, Giuseppe A. Palumbo, Daniele Vallisa, Antonio Cuneo, Gianluca Gaidano, Mario Luppi and Roberto Marasca
Type: Article
| 2018
| Item not available on this server.
Quantitative proteomic profiling of primary cancer-associated fibroblasts in oesophageal adenocarcinoma: CAF proteomic profiling in OAC - Antigoni Manousopoulou, Annette Hayden, Massimiliano Mellone, Diana J. Garay-Baquero, Cory H. White, Fergus Noble, Monette Lopez, Gareth J. Thomas, Timothy J. Underwood and Spiros D. Garbis
Type: Article
| 2018
Re. Rethinking neoadjuvant chemotherapy for breast cancer - Stuart A. McIntosh, Ramsey Cutress, Malcolm Reed and Dan Rea
Type: Letter
| 2018
A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype - Genevieve E. Melling, Sarah E. Flannery, Siti A. Abidin, Hannah Clemmens, Priyanka Prajapati, Emma E. Hinsley, Stuart Hunt, James W.F. Catto, Ricardo Della Coletta, Massimiliano Mellone, Gareth J. Thomas, E. Ken Parkinson, Stephen S. Prime, Ian C. Paterson, David J. Buttle and Daniel W. Lambert
Type: Article
| 2018
| Item not available on this server.
Type: Article
| 2018
| Item not available on this server.
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition - Christos Mikropoulos, Christina G.Hutten Selkirk, Sibel Saya, Elizabeth Bancroft, Emily Vertosick, Tokhir Dadaev, Charles Brendler, Elizabeth Page, Alexander Dias, D. Gareth Evans, Jeanette Rothwell, Lovise Maehle, Karol Axcrona, Kate Richardson, Diana Eccles, Thomas Jensen, Palle J. Osther, Christi J. Van Asperen, Hans Vasen, Lambertus A. Kiemeney, Janneke Ringelberg, Cezary Cybulski, Dominika Wokolorczyk, Rachel Hart, Wayne Glover, Jimmy Lam, Louise Taylor, Monica Salinas, Lidia Feliubadaló, Rogier Oldenburg, Ruben Cremers, Gerald Verhaegh, Wendy A. Van Zelst-Stams, Jan C. Oosterwijk, Jackie Cook, Derek J. Rosario, Saundra S. Buys, Tom Conner, Susan Domchek, Jacquelyn Powers, Margreet Gem Ausems, Manuel R. Teixeira, Sofia Maia, Louise Izatt, Rita Schmutzler, Kerstin Rhiem, William D. Foulkes, Talia Boshari, Rosemarie Davidson, Marielle Ruijs, Apollonia Tjm Helderman-Van Den Enden, Lesley Andrews, Lisa Walker, Katie Snape, Alex Henderson, Irene Jobson, Geoffrey J. Lindeman, Annelie Liljegren, Marion Harris, Muriel A. Adank, Judy Kirk, Amy Taylor, Rachel Susman, Rakefet Chen-Shtoyerman, Nicholas Pachter, Allan Spigelman, Lucy Side, Janez Zgajnar, Josefina Mora, Carole Brewer, Neus Gadea, Angela F. Brady, David Gallagher, Theo Van Os, Alan Donaldson, Vigdis Stefansdottir, Julian Barwell, Paul A. James, Declan Murphy, Eitan Friedman, Nicola Nicolai, Lynn Greenhalgh, Elias Obeid, Vedang Murthy, Lucia Copakova, John McGrath, Soo Hwang Teo, Sara Strom, Karin Kast, Daniel A. Leongamornlert, Anthony Chamberlain, Jenny Pope, Anna C. Newlin, Neil Aaronson, Audrey Ardern-Jones, Chris Bangma, Elena Castro, David Dearnaley, Jorunn Eyfjord, Alison Falconer, Christopher S. Foster, Henrik Gronberg, Freddie C. Hamdy, Oskar Johannsson, Vincent Khoo, Jan Lubinski, Eli Marie Grindedal, Joanne McKinley, Kylie Shackleton, Anita V. Mitra, Clare Moynihan, Gad Rennert, Mohnish Suri, Karen Tricker, Sue Moss, Zsofia Kote-Jarai, Andrew Vickers, Hans Lilja, Brian T. Helfand and Rosalind A. Eeles
Type: Article
| 2018
Epidermal growth factor receptor family inhibition identifies P38 Mitogen-activated protein kinase as a potential therapeutic target in bladder cancer - Regina Mora Vidal, Sergio Regufe da Mota, Annette Hayden, Hannah Markham, James Douglas, Graham Packham and Simon J. Crabb
Type: Article
| 2018
Particle accumulation in ureteral stents is governed by fluid dynamics: in vitro study using a “stent-on-chip” model - Ali Mosayyebi, Qi Yann Yue, Bhaskar K. Somani, Xunli Zhang, Costantino Manes and Dario Carugo
Type: Article
| 2018
| Item availability restricted.
Adherence to best practice consensus guidelines for implant-based breast reconstruction: Results from the iBRA National Practice Questionnaire Survey - Senthurun Mylvaganam, Elizabeth J. Conroy, Paula R. Williamson, Nicola L.P. Barnes, Ramsey I. Cutress, Matthew D. Gardiner, Abhilash Jain, Joanna M. Skillman, Steven Thrush, Lisa J. Whisker, Jane M. Blazeby, Shelley Potter and Christopher Holcombe
Type: Article
| 2018
The PI3Kδ-selective inhibitor idelalisib minimally interferes with immune effector function mediated by rituximab or obinutuzumab and significantly augments B cell depletion In vivo - Adam Palazzo, Sylvia Herter, Laura Grosmaire, Randy Jones, Christian Frey, Marina Bacac, Pablo Umana, Robert James Oldham, Michael Marshall, Kerry Cox, Anna Turaj, Mark Cragg, Christian Klein, Matthew Carter and Stacey Tannheimer
Type: Article
| 2018
Reply to ‘Comment on ‘BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses'' - E.S. Papadakis, T. Reeves, N.H. Robson, T. Maishman, G. Packham and R.I. Cutress
Type: Letter
| 2018
The partial dissociation of MHC class I bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1: ERAP1 trimming of MHC I-bound peptides - Athanasios Papakyriakou, Emma Reeves, Mary Beton, Halina Mikolajek, Leon Douglas, Grace Cooper, Timothy Elliott, Jorn M. Werner and Edward James
Type: Article
| 2018
CBL-MZ is not a single biological entity: evidence from genomic analysis and prolonged clinical follow up - H. Parker, N. McIver-Brown, Z. Davis, M. Parry, M.J.J. Rose-Zerilli, A. Xochelli, J. Gibson, R. Walewska, J.C. Strefford and D.G. Oscier
Type: Article
| 2018
Using a genetic test result in the care of family members: how does the duty of confidentiality apply - Michael Parker and Anneke Lucassen
Type: Article
| 2018
Targeting gp100 and TRP-2 with a DNA vaccine: Incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial - Poulam M. Patel, Christian H. Ottensmeier, Clive Mulatero, Paul Lorigan, Ruth Plummer, Hardev Pandha, Somaia Elsheikh, Efthymios Hadjimichael, Naty Villasanti, Michelle Cunnell, Rachael L. Metheringham, Victoria A. Brentville, Lee Machado, Ian Daniels, Mohamed Gijon, Drew Hannaman and Lindy G. Durrant
Type: Article
| 2018
Precursors of human CD4 cytotoxic T lymphocytes identified by single-cell transcriptome analysis - Veena S. Patil, Ariel Madrigal, Benjamin J. Schmiedel, James Clarke, Patrick O'Rourke, Aruna D. de Silva, Eva Harris, Bjoern Peters, Gregory Seumois, Daniela Weiskopf, Alessandro Sette and Pandurangan Vijayanand
Type: Article
| 2018
Analysis of mutation and loss of heterozygosity by whole-exome sequencing yields insights into pseudomyxoma peritonei - Reuben Pengelly, Babatunde Rowaiye, Karen Pickard, Brendan J. Moran, Sanjeev Dayal, William Tapper, Alexander Mirnezami, Tom Cecil, Faheez Mohamed, Norman Carr and Sarah Ennis
Type: Article
| 2018
| Item availability restricted.
Target-based screening against eIF4A1 reveals the marine natural product elatol as a novel inhibitor of translation initiation with in vivo antitumor activity - Tara L. Peters, Joseph Tillotson, Alison M. Yeomans, Sarah Wilmore, Elizabeth Lemm, Carlos Jimenez-Romero, Luis A. Amador, Lingxiao Li, Amit D. Amin, Praechompoo Pongtornpipat, Christopher J. Zerio, Andrew J. Ambrose, Gillian Paine-Murrieta, Patricia Greninger, Francisco Vega, Cyril H. Benes, Graham Packham, Abimael D. Rodríguez, Eli Chapman and Jonathan H. Schatz
Type: Article
| 2018
"It's like we don't exist": Tailoring education for young women undergoing surgery for early-stage breast cancer - Alejandra Recio-Saucedo, Anthony W. Gilbert, Sue Gerty, Ramsey I. Cutress, Diana Eccles and Claire Foster
Type: Article
| 2018
| Item availability restricted.
LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models - Sergio Regufe da Mota, Sarah Bailey, Rosemary A. Strivens, Annette L. Hayden, Leon R. Douglas, Patrick J. Duriez, M. Teresa Borrello, Hanae Benelkebir, A. Ganesan, Graham Packham and Simon J. Crabb
Type: Article
| 2018
Type: Letter
| 2018
CD103+CD8+ lymphocytes characterize the immune infiltration in a case with pseudoprogression in squamous NSCLC - Pedro Rocha, Max Hardy-Werbin, Dolores Naranjo, Álvaro Taus, Maite Rodrigo, Flavio Zuccarino, René Roth, Oliver Wood, Christian H. Ottensmeier and Edurne Arriola
Type: Article
| 2018
New revelations from an old receptor: Immunoregulatory functions of the inhibitory Fc gamma receptor, FcγRIIB (CD32B) - Ali Roghanian, Richard J. Stopforth, Lekh N. Dahal and Mark S. Cragg
Type: Article
| 2018
Surgeons' assessment versus risk models for predicting complications of hepato-pancreato-biliary surgery (HPB-RISC): a multicenter prospective cohort study - Morsal Samim, Timothy H. Mungroop, Mohammed Abu Hilal, Cas J. Isfordink, Quintus I. Molenaar, Marcel J. van der Poel, Thomas A. Armstrong, Arjun S. Takhar, Neil W. Pearce, John N. Primrose, Scott Harris, Helena M. Verkooijen, Thomas M. van Gulik, Jeroen Hagendoorn, Olivier R. Busch, Colin D. Johnson and Marc G. Besselink
Type: Article
| 2018
Factors influencing global health related quality of life in elderly cancer patients: Results of a secondary data analysis - Heike Schmidt, Thomas Nordhausen, Stephanie Boese, Dirk Vordermark, Sally Wheelwright, Andreas Wienke and Colin D. Johnson
Type: Article
| 2018
Serum carcinoembryonic antigen trends for diagnosing colorectal cancer recurrence in the FACS randomized clinical trial - B. Shinkins, J.N. Primrose, S.A. Pugh, B.D. Nicholson, R. Perera, T. James and D. Mant
Type: Article
| 2018
Session 2: Mutational discordance: the big challenge in personalized treatments – any solutions? - M. Siddiqui, M. Chand, C. Eng, A. Mehdizadeh, A. Mirnezami and G. Brown
Type: Article
| 2018
| Item not available on this server.
Session 2: What causes liver metastases – lymph nodes or is it something else? - M. Siddiqui, I. Nagtegaal, I. Santiago, N. Knijn, M. Berho, A. Mirnezami, S. Rao and G. Brown
Type: Article
| 2018
| Item not available on this server.
Recontacting or not recontacting?: A survey of current practices in clinical genetics centres in Europe - Fabio Sirchia, Daniele Carrieri, Sandi Dheensa, Caroline Benjamin, Hulya Kayserili, Christophe Cordier, Carla G. van El, Peter D. Turnpenny, Bela Melegh, Alvaro Mendes, Tanya F. Halbersma-Konings, Irene van Langen, Anneke M. Lucassen, Angus J. Clarke, Francesca Forzano and Susan E. Kelly
Type: Article
| 2018
Prevention of morbidity in Sickle Cell Disease phase 2 (POMS 2b pediatric): Improvement of cognition in children with Sickle Cell Disease with auto-adjusting Continuous Positive Airways Pressure: a single-blind, randomized, controlled phase II trial - A. Slee, H. Stotesbury, J. Kawadler, M. Koelbel, S. Chakravorty, M. Pelidis, S. L. Thein, J. Howard, D. Rees, S. Sahota, S. Sarkaria, C. Nwosu, D. Saunders, J. Gavlak, A. Gupta, C. Liossi and F. Kirkham
Type: Article
| 2018
| Item not available on this server.
Harnessing citizen science through mobile phone technology to screen for immunohistochemical biomarkers in bladder cancer - Peter Smittenaar, Alexandra K. Walker, Shaun McGill, Christiana Kartsonaki, Rupesh J. Robinson-Vyas, Janette P. McQuillan, Sarah Christie, Leslie Harris, Jonathan Lawson, Elizabeth Henderson, Will Howat, Andrew Hanby, Gareth J. Thomas, Selina Bhattarai, Lisa Browning and Anne E. Kiltie
Type: Article
| 2018
Deleting malignant B-cells with second-generation anti-CD20 antibodies - Joshua Sopp and Mark S. Cragg
Type: Article
| 2018
| Item availability restricted.
Assessment of nuclear ZEB2 as a biomarker for colorectal cancer outcome and TNM risk stratification - Rahul Sreekumar, Scott Harris, Karwan Moutasim, Ricardo DeMateos, Ashish Patel, Katherine Emo, Sophie White, Tamer Yagci, Eugene Tulchinsky, Gareth Thomas, John N Primrose, A Emre Sayan and Alex H Mirnezami
Type: Article
| 2018
Introduction to a review series on therapeutic antibodies - Freda K. Stevenson and Catherine M. Bollard
Type: Article
| 2018
| Item not available on this server.
Detection of experimental and clinical immune complexes by measuring SHIP-1 recruitment to the inhibitory FcγRIIB - R.J. Stopforth, R.J. Oldham, A.L. Tutt, P. Duriez, H.T.C. Chan, B. Binkowski, C. Zimprich, D. Li, P. Hargreaves, M. Cong, V. Reddy, M. Leandro, G. Cambridge, A. Lux, F. Nimmerjahn and M.S. Cragg
Type: Article
| 2018
| Item availability restricted.
The genomic and epigenomic landscape of chronic lymphocytic leukemia - Jonathan C. Strefford, Renata Walewska and David G. Oscier
Type: Book Section
| 2018
| Springer
| Item not available on this server.
Evaluating anti-CD32b F(ab) conformation using molecular dynamics and small-angle X-ray scattering - Emma, Jill Sutton, Richard Bradshaw, Christian Orr, Björn Frendéus, Gunilla Larsson, Ingrid Teige, Mark Cragg, Ivo Tews and Jonathan W. Essex
Type: Article
| 2018
Proactive multi-modality treatment of Pancreatic Neuroendocrine Tumours (PNETs): Potential survival benefits - L. Tanno, D. Mayo, S. Mills, A. Takhar, J. Cave, L. Nolan, B. Stedman, F.X. Sundram, M. Abu Hilal, H. Connor, N. Pearce and T. Armstrong
Type: Article
| 2018
| Item not available on this server.
Clinical testing of BRCA1 and BRCA2: A worldwide snapshot of technological practices - Amanda Ewart Toland, Andrea Forman, Fergus J. Couch, Julie O. Culver, Diana M. Eccles, William D. Foulkes, Frans B.L. Hogervorst, Claude Houdayer, Ephrat Levy-Lahad, Alvaro N. Monteiro, Susan L. Neuhausen, Sharon E. Plon, Shyam K. Sharan, Amanda B. Spurdle, Csilla Szabo and Lawrence C. Brody
Type: Article
| 2018
Prognostic value of end-of-induction PET response after first-line immunochemotherapy for follicular lymphoma (GALLIUM): secondary analysis of a randomised, phase 3 trial - Judith Trotman, Sally F. Barrington, David Belada, Michel Meignan, Robert MacEwan, Carolyn Owen, Václav Ptáčník, András Rosta, Günter R. Fingerle-Rowson, Jiawen Zhu, Tina Nielsen, Deniz Sahin, Wolfgang Hiddemann, Robert E. Marcus and Andrew Davies
Type: Article
| 2018
Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody crosslinking - Anna H. Turaj, Kerry L. Cox, Christine A. Penfold, Ruth R. French, C. Ian Mockridge, Jane E. Willoughby, Alison L. Tutt, Jordana Griffiths, Peter W.M. Johnson, Martin J. Glennie, Ronald Levy, Mark S. Cragg and Sean H. Lim
Type: Article
| 2018
Type: Article
| 2018
IL-12 and IL-7 synergise to control MAIT cell cytotoxic responses to bacterial infection - Joshua C. Wallington, Anthony P. Williams, Karl J. Staples and Tom M.A Wilkinson
Type: Article
| 2018
Targeting head and neck cancer by vaccination - Chuan Wang, James Dickie, Ruhcha Sutavani, Catherine Pointer, Gareth Thomas and Natalia Savelyeva
Type: Article
| 2018
Nurses’ use of appropriate needle sizes when administering intramuscular injections - Sheila White, John Goodwin and Laura Behan
Type: Article
| 2018
| Item not available on this server.
Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer - Bradleigh Whitton, Haruko Okamoto, Graham Packham and Simon Crabb
Type: Review
| 2018
Impact of radiologically stratified exacerbations: Insights into pneumonia aetiology in COPD - Nicholas P. Williams, Kristoffer Ostridge, Jeanne-Marie Devaster, Viktoriya Kim, Ngaire A. Coombs, Simon Bourne, Stuart C. Clarke, Stephen Harden, Ausami Abbas, Emmanuel Aris, Christophe Lambert, Andrew Tuck, Anthony Williams, Stephen Wootton, Karl J. Staples and Tom M.A. Wilkinson
Type: Article
| 2018
The clinical importance of DNA methylation signatures in chronic lymphocytic leukemia patients treated with chemo-immunotherapy - Tomasz K. Wojdacz, Harindra E. Amarasinghe, Matthew J. J. Rose-Zerilli, Alice Beattie, Jade Forster, Latha Kadalayil, Stuart Blakemore, Helen Parker, Marta Larrayoz, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J. Steele, Richard Rosenquist, Andrew Collins, Andrew Pettitt, Peter Hillmen, Christoph Plass, Anna Schuh, Daniel Catovsky, David G. Oscier, Christopher C. Oakes and Jonathan C. Strefford
Type: Meeting abstract
| 2018
| Item not available on this server.
Paracrine signalling during ZEB1-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in lung fibrosis. - Liudi Yao, Franco Conforti and Charlotte Hill
Type: Article
| 2018
Complex interplay between epitope specificity and isotype dictates the biological activity of anti-human CD40 antibodies - Xiaojie Yu, Hak Chan, Christian Orr, Osman Dadas, Steven Booth, Lekh Dahal, Christine Penfold, Lyn O'Brien, Christopher Mockridge, Ruth French, Patrick Duriez, Leon Douglas, Arwen R. Pearson, Mark Cragg, Ivo Tews, Martin Glennie and Ann L. White
Type: Article
| 2018
Increased circulating resistin levels in early-onset breast cancer patients of normal body mass index correlate with lymphnode negative involvement and longer disease free survival; a multi-center POSH cohort serum proteomics study - Bashar Zeidan, Antigoni Manousopoulou, Diana J. Garay Baquero, Cory H. White, Samantha E.T. Larkin, Kathleen N. Potter, Theodoros I. Roumeliotis, Evangelia K. Papachristou, Ellen Copson, Ramsey I. Cutress, Stephen A. Beers, Diana Eccles, Paul A. Townsend and Spiros D. Garbis
Type: Article
| 2018
Circulating resistin in early-onset breast cancer patients with normal body mass index correlate with disease-free survival and lymph node involvement - Bashar Zeidan, Antigoni Manousopoulou, Diana Garay-Baquero, Cory White, Samantha Larkin, Theodoros Roumeliotis, Evangelia Papachristou, Ellen Copson, Ramsey Cutress, Kathleen Potter, Stephen Beers, Diana Eccles, Paul Townsend and Spiros Garbis
Type: Meeting abstract
| 2018
| Item not available on this server.
An unexpected protective role of low affinity allergen-specific IgG via the inhibitory receptor FcγRIIb - Lisha Zha, Fabiana Leoratti, Lichun He, Mona Mohsen, Federico Stomi, Monique Vogel, Martin Bachmann and Mark Cragg
Type: Article
| 2018
Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation article - Qing Zhou, Sahar Eldakhakhny, Franco Conforti, Emma J. Crosbie, Gerry Melino and Berna S. Sayan
Type: Article
| 2018