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Items where Division is "Current Faculties > Faculty of Medicine > Cancer Sciences
Cancer Sciences" and Year is 2019

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Number of items: 193.

Type: Patent | 2019 | Item not available on this server.

Type: Patent | 2019 | Item availability restricted.

Type: Patent | 2019 | Item not available on this server.

Against antibacterial and antifungal activity of jojoba wax liquid (Simmondsia chinensis) - Ahmed Al-Ghamdi, Thanaa Elkholy, Shahd Abuhelal, Hatim Al-Abbadi, Dina Qahwaji, Nahlaa Khalefah, Hanaan Sobhy and Mohammad Abu-Hilal
Type: Article | 2019

Interferon lambda 4 impacts the genetic diversity of hepatitis C virus - M. Azim Ansari, Elihu Aranday-cortes, Camilla Lc Ip, Ana Da Silva Filipe, Siu Hin Lau, Connor Bamford, David Bonsall, Amy Trebes, Paolo Piazza, Vattipally Sreenu, Vanessa M Cowton, J. Ball, E. Barnes, G. Burgess, G Cooke, J Dillon, G. Foster, C. Gore, N Guha, R Halford, C. Holmes, Emma Hudson, S Hutchinson, W. Irving, S Khakoo, Paul Klenerman, N. Martin, T Mbisa, J Mckeating, John Mclauchlan, A. Miners, A Murray, P Shaw, P Simmonds, S Smith, C Spencer, E Thomson, P Troke, P Vickerman, N Zitzmann, Emma Hudson, Rory Bowden, Arvind H Patel, Graham R Foster, William L Irving, Kosh Agarwal, Emma C Thomson, P. Simmonds, Paul Klenerman, Chris Holmes, Eleanor Barnes, Chris Ca Spencer, John Mclauchlan and Vincent Pedergnana
Type: Article | 2019

Nivolumab for relapsed/refractory diffuse large B-Cell lymphoma in patients ineligible for or having failed autologous transplantation: a single-arm, Phase II Study - Stephen M. Ansell, Monique C. Minnema, Peter Johnson, John M. Timmerman, Philippe Armand, Margaret A. Shipp, Scott J. Rodig, Azra H. Ligon, Margaretha G.M. Roemer, Nishitha Reddy, Jonathon B. Cohen, Sarit Assouline, Michelle Poon, Manish Sharma, Kazunobu Kato, Selda Samakoglu, Anne Sumbul and Andrew Grigg
Type: Article | 2019

Genome-wide promoter methylation of hairy cell leukemia - Alberto J. Arribas, Andrea Rinaldi, Giorgia Chiodin, Ivo Kwee, Afua Adjeiwaa Mensah, Luciano Cascione, Davide Rossi, Meena Kanduri, Richard Rosenquist, Emanuele Zucca, Peter W. Johnson, Gianluca Gaidano, Christopher C. Oakes, Francesco Bertoni and Francesco Forconi
Type: Article | 2019

Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter's syndrome: therapeutic implications - Francesca Arruga, Valeria Bracciamà, Nicoletta Vitale, Tiziana Vaisitti, Katiuscia Gizzi, Alison Yeomans, Marta Coscia, Giovanni D'Arena, Gianluca Gaidano, John N. Allan, Richard R. Furman, Graham Packham, Francesco Forconi and Silvia Deaglio
Type: Article | 2019 | Item not available on this server.

Type: Article | 2019

Type: Article | 2019

Type: Article | 2019 | Item not available on this server.

The impact of cisplatin- or non-cisplatin-containing chemotherapy on long-term and conditional survival of patients with advanced urinary tract cancer - Aristotelis Bamias, Kimon Tzannis, Christina Bamia, Lauren C Harshman, Simon Crabb, Elizabeth R Plimack, Sumanta Pal, Ugo De Giorgi, Sylvain Ladoire, Christine Theodore, Neeraj Agarwal, Evan Y Yu, Guenter Niegisch, Cora N Sternberg, Sandy Srinivas, Ulka Vaishampayan, Andrea Necchi, Michalis Liontos, Jonathan E Rosenberg, Thomas Powles, Joaquim Bellmunt and Matthew D Galsky
Type: Article | 2019

Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerisation - Arindam Banerjee, Charles Birts, Matthew Darley, Rachel Parker, Alexander Mirnezami, Jonathan West, Ramsey Cutress, Stephen Beers, Matthew Rose-Zerilli and Jeremy Blaydes
Type: Article | 2019

Positron emission tomography score has greater prognostic significance than pretreatment risk stratification in early-stage Hodgkin lymphoma in the UK RAPID study - Sally F. Barrington, Elizabeth H. Phillips, Nicholas Counsell, Barry Hancock, Ruth Pettengell, Peter Johnson, William Townsend, Dominic Culligan, Bilyana Popova, Laura Clifton-Hadley, Andrew McMillan, Peter Hoskin, Michael J. O'Doherty, Tim Illidge and John Radford
Type: Article | 2019

Type: Review | 2019

PEPtalk2: Results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer - Jessica Bate, Stephen Baker, Judith Breuer, Julia C. Chisholm, Juliet Gray, Sophie Hambleton, Aimee Houlton, Mark Jit, Stephen Lowis, Guy Makin, Catherine O'Sullivan, Soonie R. Patel, Robert Phillips, Neil Ransinghe, Mary Elizabeth Ramsay, Roderick Skinner, Keith Wheatley and Paul T. Heath
Type: Article | 2019 | Item not available on this server.

Thirteen-valent pneumococcal conjugate vaccine in children with acute lymphoblastic leukemia: Protective immunity can be achieved on completion of treatment - Jessica Bate, Ray Borrow, Julia C. Chisholm, Stuart Clarke, Elizabeth Dixon, Saul Faust, Angeliki Galanopoulou, David Goldblatt, Paul T. Heath, Thomas Maishman, Susan Mapstone, Soonie R. Patel, Antony P. Williams and Juliet Gray
Type: Article | 2019

Cartilage binding antibodies induce pain through immune complex mediated activation of neurons - Alex Bersellini Farinotti, Gustaf Wigerblad, Diana Nascimento, Duygu B. Bas, Carlos Morado Urbina, Kutty Selva Nandakumar, Katalin Sandor, Bingze Xu, Sally Abdelmoaty, Matthew A. Hunt, Kristina Angeby Moller, Azar Baharpoor, Jon Sinclair, Kent Jardemark, Johanna T. Lanner, Ia Khmaladze, Lars E. Borm, Lu Zhang, Fredrik Wermeling, Mark Cragg, Johan Lengqvist, Anne-Julie Chabot-Dore, Luda Diatchenko, Inna Belfer, Mattias Collin, Kim Kultima, Birgitta Heyman, Juan M. Andrade Jimenez, Simone Codeluppi, Rikard Holmdahl and Camilla I. Svensson
Type: Article | 2019

Type: Article | 2019 | Item not available on this server.

Type: Article | 2019

Protocol for developing quality assurance measures to use in surgical trials: an example from the ROMIO study - Natalie S Blencowe, Anni Skilton, Daisy Gaunt, Rachel Brierley, Andrew Hollowood, Simon Dwerryhouse, Simon Higgs, William Robb, Alex Boddy, George Hanna, C Paul Barham and Jane Blazeby
Type: Article | 2019

Type: Article | 2019 | Item not available on this server.

Lanthanides compete with calcium for binding to cadherins and inhibit cadherin-mediated cell adhesion - Lewis L. Brayshaw, Rosanna C.G. Smith, Magd Badaoui, James A. Irving and Stephen R. Price
Type: Article | 2019 | Item not available on this server.

Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer--the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT) - Rachel C. Brierley, Daisy Gaunt, Chris Metcalf, Jane M. Blazeby, Natalie M. Blencowe, Marcus Jepson, Richard G. Berrisford, Kerry N.L. Avery, William Hollingworth, Caoimhe T. Rice, Aide Moure-Fernandez, Newton Wong, Joanna Nicklin, Anni Skilton, Alex Boddy, James P. Byrne, Timothy Underwood, Ravi Vohra, James A. Cotton, Kish Pursani, Rachel Melhado, Bilal Alkhaffaf, Richard Krysztopik, Peter Lamb, Lucy Culliford, Chris Rogers, Benjamin Howes, Katy Chalmers, Sian Cousins, Jackie Ellitt, Jenny Donovan, Rachael Hayes, Robin A. Wickens, Paul Wilkerson, Andrew Hollowood, Christopher Streets, Dan Titcomb, Martyn Lee Humphreys, Tim Wheatley, Grant Sanders, Arun Ariyarathenam, Jamie Kelly, Fergus Noble, Graeme Couper, Richard J.E. Skipworth, Chris Deans, Sukhibir Ubhi, Robert Williams, David Bowrey, David Exon, Paul Turner, Vinutha Daya Shetty, Ram Chaparala, Khurshid Akhtar, Naheed Farooq, Simon L. Parsons, Neil T. Welch, Rebecca J. Houlihan, Joanne Smith, Rachel Schranz, Nicola Rea, Jill Cooke, Alexandra Williams, Carolyn Hindmarsh, Sally Maitland, Lucy Howie and Christopher Paul Barham
Type: Article | 2019

Survey of UK histopathology consultants' attitudes towards academic and molecular pathology - Scarlet Brockmoeller, Caroline Young, Jessica Lee, Mark J. Arends, Bridget S. Wilkins, Gareth J. Thomas, Karin A. Oien, Louise Jones and Keith D. Hunter
Type: Article | 2019

Type: Monograph | 2019 | University of Southampton

Immunological methods to study monoclonal antibody activity - Matthew Carter, Lekh Dahal, Kirstie Cleary, Michael Marshall, Ruth French, Stephen Beers and Mark Cragg
Type: Book Section | 2019 | Humana Press

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis - Dilip K. Challa, Xiaoli Wang, Hector Pérez Montoyo, Ramraj Velmurugan, Raimund Ober and E. Sally Ward
Type: Article | 2019

Type: Article | 2019

Hedgehog activation in CLL - Giorgia Chiodin and Francesco Forconi
Type: Review | 2019 | Item not available on this server.

Cohort profile: Design and methods in the eye and vision consortium of UK Biobank - Sharon Yu Lin Chua, Dhanes Thomas, Naomi Allen, Andrew Lotery, Parul Desai, Praveen Patel, Zaynah Muthy, Cathie Sudlow, Tunde Peto, Peng Tee Khaw, Paul J. Foster, Yalin Zheng, Tariq Aslam, Sarah A. Barman, Jenny H. Barrett, Paul Bishop, Peter Blows, Catey Bunce, Roxana O. Carare, Usha Chakravarthy, Michelle Chan, David P. Crabb, Philippa M. Cumberland, Alexander Day, Bal Dhillon, Andrew D. Dick, Cathy Egan, Sarah Ennis, Marcus Fruttiger, John E.J. Gallacher, David F. Garway-Heath, Jane Gibson, Dan Gore, Jeremy A. Guggenheim, Chris J. Hammond, Alison Hardcastle, Simon P. Harding, Ruth E. Hogg, Pirro Hysi, Pearse A. Keane, Anthony P. Khawaja, Gerassimos Lascaratos, Tom MacGillivray, Sarah Mackie, Keith Martin, Michelle McGaughey, Bernadette McGuinness, Gareth J. McKay, James E. Morgan and Jay Self
Type: Review | 2019

Prostate cancer androgen receptor splice variant 7 biomarker study - A multicentre randomised feasibility trial of biomarker-guided personalised treatment in patients with advanced prostate cancer (the VARIANT trial) study protocol - Emma Clark, Miranda Morton, Shriya Sharma, Holly Fisher, Denise Howel, Jenn Walker, Ruth Wood, Helen Hancock, Rebecca Maier, John Marshall, Amit Bahl, Simon Crabb, Suneil Jain, Ian Pedley, Rob Jones, John Staffurth and Rakesh Heer
Type: Article | 2019

Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer - James Clarke, Bharat Panwar, Ariel Madrigal, Divya Singh, Ravindra Gujar, Oliver Wood, Serena, Jamie Tzu Wen Chee, Eschweiler Simon, Emma King, Amiera Awad, Christopher Hanley, Katy Mccann, Sourya Bhattacharyya, Edwin Woo, Aiman Alzetani, Gregory Seumois, Gareth Thomas, Anusha-Preethi Ganesan, Peter Friedmann, Tilman Sanchez-Elsner, Ferhat Ay, Christian Ottensmeier and Pandurangan Vijayanand
Type: Article | 2019

Resolution limit of image analysis algorithms - Edward A.K. Cohen, Anish V. Abraham, Sreevidhya Ramakrishnan and Raimund J. Ober
Type: Article | 2019

Type: Editorial | 2019 | Item not available on this server.

Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit - Francesco Cucco, Sharon Barrans, Alexandra Clipson, Chulin Sha, Simon Crouch, Rachel Dobson, Zi Chen, Joe Sneath Thompson, Matthew Care, Thomas EC Cummin, Joshua Caddy, Hongxiang Liu, Anne Robinson, Anna Schuh, Jude Fitzgibbon, Daniel Painter, Alexandra Smith, Eve Roman, Reuben Tooze, Catherine Burton, Andrew Davies, David Westhead, Peter Johnson and Ming-Qing Du
Type: Article | 2019

Targeted therapeutics for lymphoma: Using biology to inform treatment - Thomas Cummin, Mark Cragg, Jonathan W. Friedberg and Peter Johnson
Type: Book Section | 2019 | Springer | Item availability restricted.

Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics? - Andrew F. Cumpstey, Magdalena Minnion, Bernadette Fernandez, Monika Mikus-Lelinska, Kay Mitchell, Dan S. Martin, Michael Grocott and Martin Feelisch
Type: Article | 2019

The management of primary mediastinal B-cell lymphoma: a British Society for Haematology Good Practice Paper - Kate Cwynarski, Maria A.V. Marzolini, Sally F. Barrington, George Follows, Timothy Illidge, Simon Stern and Andrew Davies
Type: Article | 2019 | Item availability restricted.

Recurrent group A tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells - Jennifer M. Dan, Colin Havenar-Daughton, Kayla Kendric, Rita Al-Kolla, Kirti Kaushik, Sandy L. Rosales, Ericka L. Anderson, Christopher N. LaRock, Pandurangan Vijayanand, Grégory Seumois, David Layfield, Ramsey I. Cutress, Christian H. Ottensmeier, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Victor Nizet, Marcella Bothwell, Matthew Brigger and Shane Crotty
Type: Article | 2019

Type: Article | 2019 | Item not available on this server.

Gene expression profiling in an open-label randomised phase 3 trial (REMoDL-B) of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma - Andrew Davies, Thomas Cummin, Sharon Barrans, Tom Maishman, Christoph Mamot, Urban Novak, Joshua Caddy, Louise Stanton, Shamim Kazmi-Stokes, Andrew McMillan, Paul Fields, Christopher Pocock, Graham Collins, Richard Stephens, Francesco Cucco, Alexandra Clipson, Chulin Sha, Reuben Tooze, Matthew A. Care, Gareth Griffiths, Ming-Qing Du, David Westhead, Catherine Burton and Peter Johnson
Type: Article | 2019

Transglutaminase-2 mediates the biomechanical properties of the colorectal cancer tissue microenvironment that contribute to disease progression - Robin Delaine-Smith, Nicola Wright, Chris Hanley, Rebecca Hanwell, Rahul Bhome, Marc Bullock, Cole Drifka, Kevin W. Eliceiri, Gareth Thomas, Martin Knight, Alexander Mirnezami and Nicholas Peake
Type: Article | 2019

International perspectives on the implementation of reproductive carrier screening - Martin Delatyki, Fowzan S. Alkuraya, Alison Archibald, Carlo Castellani, Martina C. Cornel, Wayne W. Grody, Lidewij Henneman, Adonis S. Ioannides, Edwin Kirk, Nigel Laing, Anneke Lucassen, John Massie, Juliette Schuurmans, Meow-Keong Thong, Irene M. Van Langen and Joel Zlotogora
Type: Article | 2019

Sizing up blast injury research - transforming the effectiveness and relevance of blast injury research - Jack Denny, Alexander Dickinson, Rebecca Brown and James Batchelor
Type: Monograph | 2019 | University of Southampton | Item availability restricted.

Type: Thesis | 2019 | University of Southampton

Familial genetic risks: how can we better navigate patient confidentiality and appropriate risk disclosure to relatives? - Edward Dove, Vicky Chico, Michael Fay, Graeme Laurie, Anneke Lucassen and Emily Postan
Type: Article | 2019

Ibrutinib therapy releases leukemic surface IgM from antigen drive in chronic lymphocytic leukemia patients - Samantha J Drennan, Giorgia Chiodin, Annalisa D'Avola, Ian Tracy, Peter W. Johnson, Livio Trentin, Andrew J. Steele, Graham Packham, Freda K. Stevenson and Francesco Forconi
Type: Article | 2019

Type: Article | 2019

Type: Article | 2019

Maternal outcomes in subsequent delivery after previous obstetric anal sphincter injury (OASI): a multi-centre retrospective cohort study - Joanna Caroline D’Souza, Ash Monga, Douglas G. Tincello, Abdul H. Sultan, Ranee Thakar, Timothy C. Hillard, Stephanie Grigsby, Ayisha Kibria, Clare F. Jordan and Christopher Ashmore
Type: Article | 2019

Reinterpretation, reclassification, and its downstream effects: challenges for clinical laboratory geneticists - Julia El Mecky, Lennart Johansson, Mirjam Plantinga, Angela Fenwick, Anneke Lucassen, Trijnie Dijkhuizen, annemieke van der Hout, Kate Lyle and Irene M. Van Langen
Type: Article | 2019

A phase II study to assess the safety and efficacy of the dual mTORC1/2 inhibitor vistusertib in relapsed, refractory DLBCL: dual mTORC1/2 inhibition in relapsed, refractory DLBCL - Toby Eyre, Catherine Hildyard, Angela Hamblin, Ayesha Ali, Aimee Houlton, Louise Hopkins, Daniel Royston, Kim Linton, Andrew Pettitt, Simon Rule, Kate Cwynarski, Sally Barrington, Victoria Warbey, David Wrench, Sharon Barrans, Caroline Hirst, Anesh Panchal, Martine Roudier, Elizabeth Harrington, Andrew Davies and Graham Collins
Type: Article | 2019

Efficacy of venetoclax monotherapy in patients with relapsed chronic lymphocytic leukaemia in the post-BCR inhibitor setting: a UK wide analysis - Toby A. Eyre, Amy A. Kirkwood, Sat Gohill, George Follows, Renata Walewska, Harriet Walter, Matthew Cross, Francesco Forconi, Nimish Shah, Richard Chasty, Alistair Hart, Angus Broom, Helen Marr, Piers E.M. Patten, Andy Dann, Arvind Arumainathan, Tal Munir, Paneesha Shankara, Adrian Bloor, Rosalynd Johnston, Kim Orchard, Anna H. Schuh and Christopher P. Fox
Type: Article | 2019

The efficacy and safety of venetoclax therapy in elderly patients with relapsed, refractory chronic lymphocytic leukaemia - Toby A. Eyre, Lindsey E. Roeker, Christopher P. Fox, Satyen H. Gohill, Renata Walewska, Harriet S. Walter, Francesco Forconi, Angus Broom, Arvind Arumainathan, Danielle M. Brander, John N. Allan, Stephen J. Schuster, Brian T. Hill, Frederick Lansigan, Bruce D. Cheson, Nicole Lamanna, Catherine C. Coombs, Paul M. Barr, Alan P. Skarbnik, Mazyar Shadman, Chaitra S. Ujjani, Laurie Pearson, John M. Pagel, Ryan Jacobs and Anthony R. Mato
Type: Article | 2019

A cost-effectiveness analysis of shortened direct-acting antiviral treatment in genotype 1 noncirrhotic treatment-naive patients with chronic hepatitis C virus - Christopher G. Fawsitt, Peter Vickerman, Graham Cooke, Nicky J. Welton, Eleanor Barnes, Jonathan Ball, Diana Brainard, Gary Burgess, Graham Cooke, John Dillon, Graham Foster, Charles Gore, Neil Guha, Rachel Halford, Kevin Whitby, Chris Holmes, Anita Howe, Emma Hudson, Sharon Hutchinson, William Irving, Salim Khakoo, Paul Klenerman, Natasha Martin, Benedetta Massetto, Tamyo Mbisa, John Mchutchison, Jane Mckeating, John Mclauchlan, Alec Miners, Andrea Murray, Peter Shaw, Peter Simmonds, Chris Spencer, Emma Thomson, Peter Vickerman and Nicole Zitzmann
Type: Article | 2019

European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death - Florence Fellmann, Carla G. van El, Philippe Charron, Katarzyna Michaud, Heidi C. Howard, Sarah N. Boers, Angus J. Clarke, Anne Marie Duguet, Francesca Forzano, Silke Kauferstein, Hülya Kayserili, Anneke Lucassen, Álvaro Mendes, Christine Patch, Dragica Radojkovic, Emmanuelle Rial-Sebbag, Mary N. Sheppard, Anne Marie Tassé, Sehime G. Temel, Antti Sajantila, Cristina Basso, Arthur A.M. Wilde and Martina C. Cornel
Type: Article | 2019 | Item not available on this server.

HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma - Jason Fleming, Jeongmin Woo, Karwan Moutasim, Massimiliano Mellone, Steven Frampton, Abbie Mead, Waseem Ahmed, Oliver Wood, Hollie Robinson, Matthew Ward, Christopher H. Woelk, Christian Ottensmeier, Emma King, Dae Kim, Jeremy P. Blaydes and Gareth Thomas
Type: Article | 2019

Guidelines for the diagnosis and management of primary central nervous system diffuse large B-cell lymphoma - Christopher Fox, Elizabeth Phillips, Jeffrey Smith, Kim Linton, Eve Gallop-Evans, Claire Hemmaway, Dorothee Auer, Charlotte Fuller, Andrew Davies, Pamela McKay and Kate Cwynarski
Type: Article | 2019

Type: Article | 2019

Mesenchymal stromal cells for acute graft-versus-host disease: response at 1 week predicts probability of survival - Antonio Galleu, Dragana Milojkovic, Simona Deplano, Richard Szydlo, Sandra Loaiza, Robert Wynn, David I. Marks, Deborah Richardson, Kim Orchard, Edward Kanfer, Eleni Tholouli, Muhammad Saif, Ponni Sivaprakasam, Sarah Lawson, Adrian Bloor, Antonio Pagliuca, Victoria Potter, Varun Mehra, John A. Snowden, Ajay Vora, Bhuvan Kishore, Hannah Hunter, Jane F. Apperley and Francesco Dazzi
Type: Article | 2019 | Item not available on this server.

Predictors of weight gain in a cohort of premenopausal early breast cancer patients receiving chemotherapy - Ashu Gandhi, Ellen Copson, Diana Eccles, Lorraine Durcan, Anthony Howell, Julie Morris, Sacha Howell, Sarah McDiarmid, Katharine Sellers, D. Gareth Evans and Michelle Harvie
Type: Article | 2019

Author Correction: Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 (Scientific Reports, (2016), 6, 1, (32417), 10.1038/srep32417) - Edwin Garcia, Annette Hayden, Charles Birts, Edward Britton, Connor Rogerson, Christopher W. Bleaney, Andrew Cowie, Karen Pickard, Massimiliano Mellone, Clarisa Choh, Mathieu Derouet, Patrick Duriez, Fergus Noble, Michael J. White, John N. Primrose, Jonathan C. Strefford, Matthew Rose-Zerilli, Gareth J. Thomas, Yeng Ang, Andrew D. Sharrocks, Rebecca C. Fitzgerald, Timothy J. Underwood and Rachael Fels Elliott
Type: Letter | 2019

Regulation of the bone vascular network is sexually dimorphic - Alice Goring, Aikta Sharma, Behazad Javaheri, Rosanna Smith, Janos Kanczler, Alan Boyde, Eric Hesse, Sumeet Mahajan, Bjorn Olsen, Andrew Pitsillides, Philipp Schneider, Richard Oreffo and Claire Clarkin
Type: Article | 2019

Pattern recognition receptor polymorphisms as predictors of oxaliplatin benefit in colorectal cancer - Victoria Gray, Sarah Briggs, Claire Palles, Emma Jaeger, Timothy Iveson, Rachel Kerr, Mark P. Saunders, James Paul, Andrea Harkin, John McQueen, Matthew G. Summers, Elaine Johnstone, Haitao Wang, Laura Gatcombe, Timothy S. Maughan, Richard Kaplan, Valentina Escott-Price, Nada A. Al-Tassan, Brian F. Meyer, Salma M. Wakil, Richard S. Houlston, Jeremy P. Cheadle, Ian Tomlinson and David N. Church
Type: Article | 2019 | Item not available on this server.

Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis - Eleonora Grisard, Michela Coan, Laura Cesaratto, Ilenia Rigo, Luigi Zandonà, Alice Paulitti, Eva Andreuzzi, Gian Luca Rampioni Vinciguerra, Evelina Poletto, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Matteo Turetta, Erik Dassi, Alex Mirnezami, Vincenzo Canzonieri, Andrea Vecchione, Gustavo Baldassarre, Maurizio Mongiat, Riccardo Spizzo and Milena S. Nicoloso
Type: Article | 2019

Organizing health inequalities?: employee-driven innovation and the transformation of care - Susan Halford, Alison Fuller, Katy Lyle and Rebecca Taylor
Type: Article | 2019

Radiological response heterogeneity is of prognostic significance in metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy - Peter E. Hall, Scott T.C. Shepherd, Janet Brown, James Larkin, Robert Jones, Christy Ralph, Robert Hawkins, Simon Chowdhury, Ekaterini Boleti, Amit Bahl, Kate Fife, Andrew Webb, Simon J. Crabb, Thomas Geldart, Robert Hill, Joanna Dunlop, Duncan McLaren, Charlotte Ackerman, Akhila Wimalasingham, Luis Beltran, Paul Nathan and Thomas Powles
Type: Article | 2019

Tau misfolding efficiently propagates between individual intact hippocampal neurons - Grace Hallinan, Mariana Vargas-Caballero, Jonathan West and Katrin Deinhardt
Type: Article | 2019

Serum cytokine levels as predictive biomarkers of benefit from ipilimumab in small cell lung cancer - Max Hardy-Werbin, Pedro Rocha, Oriol Arpi, Álvaro Taus, Lara Nonell, Xavier Durán, Xavier Villanueva, Deborah Joseph-Pietras, Luke Nolan, Sarah Danson, Richard Griffiths, Miguel Lopez-Botet, Ana Rovira, Joan Albanell, Christian Ottensmeier and Edurne Arriola
Type: Article | 2019

An evaluation of different classification algorithms for protein sequence-based reverse vaccinology prediction - Ashley Heinson, Robert Ewing, John Holloway, Christopher H. Woelk and Mahesan Niranjan
Type: Article | 2019

Actively personalized vaccination trial for newly diagnosed glioblastoma - Norbert Hilf, Sabrina Kuttruff-Coqui, Katrin Frenzel, Valesca Bukur, Stefan Stevanović, Cécile Gouttefangeas, Michael Platten, Ghazaleh Tabatabai, Valerie Dutoit, Sjoerd H. van der Burg, Per thor Straten, Francisco Martínez-Ricarte, Berta Ponsati, Hideho Okada, Ulrik Lassen, Arie Admon, Christian H. Ottensmeier, Alexander Ulges, Sebastian Kreiter, Andreas von Deimling, Marco Skardelly, Denis Migliorini, Judith R. Kroep, Manja Idorn, Jordi Rodon, Jordi Piró, Hans S. Poulsen, Bracha Shraibman, Katy McCann, Regina Mendrzyk, Martin Löwer, Monika Stieglbauer, Cedrik M. Britten, David Capper, Marij J.P. Welters, Juan Sahuquillo, Katharina Kiesel, Evelyna Derhovanessian, Elisa Rusch, Lukas Bunse, Colette Song, Sandra Heesch, Claudia Wagner, Alexandra Kemmer-Brück, Jörg Ludwig, John C. Castle, Oliver Schoor, Arbel D. Tadmor, Edward Green, Jens Fritsche, Miriam Meyer, Nina Pawlowski, Sonja Dorner, Franziska Hoffgaard, Bernhard Rössler, Dominik Maurer, Toni Weinschenk, Carsten Reinhardt, Christoph Huber, Hans Georg Rammensee, Harpreet Singh-Jasuja, Ugur Sahin, Pierre Yves Dietrich and Wolfgang Wick
Type: Letter | 2019

Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis - Charlotte Hill, Juanjuan Li, Dian Liu, Franco Conforti, Christopher, J Brereton, Liudi Yao, Yilu Zhou, Aiman Alzetani, Serena, Jamie Tzu Wen Chee, ben marshall, Sophie Fletcher, David Hancock, Christian Ottensmeier, Andrew Steele, Julian Downward, Luca Richeldi, Xin Lu, Donna Davies, Mark Jones and Yihua Wang
Type: Article | 2019

Ibrutinib plus venetoclax in relapsed/refractory chronic lymphocytic leukemia: The CLARITY Study - Peter Hillmen, Andy C. Rawstron, Kristian Brock, Samuel Muñoz-Vicente, Francesca J. Yates, Rebecca Bishop, Rebecca Boucher, Donald MacDonald, Christopher Fegan, Alison McCaig, Anna Schuh, Andrew Pettitt, John G. Gribben, Piers E.M. Patten, Stephen Devereux, Adrian Bloor, Christopher P. Fox, Francesco Forconi and Talha Munir
Type: Article | 2019

Asymmetric confinement for defining outgrowth directionality - Paul Holloway, Grace Hallinan, Manjunath Hegde, Simon I.R. Lane, Katrin Deinhardt and Jonathan West
Type: Article | 2019

Type: Article | 2019

Direct-to-consumer genetic testing - Rachel Horton, Gillian Crawford, Lindsey Freema, Angela Fenwick, Caroline F. Wright and Anneke Lucassen
Type: Article | 2019

Direct-to-consumer genetic testing with third party interpretation: beware of spurious results - Rachel Horton, Gillian Crawford, Lindsey Freeman, Angela Fenwick and Anneke Lucassen
Type: Article | 2019

Type: Letter | 2019

Consent and autonomy in the genomics era - Rachel Horton and Anneke Lucassen
Type: Article | 2019

The genetic road ahead - Rachel Horton and Anneke Lucassen
Type: Letter | 2019 | Item not available on this server.

Type: Article | 2019

Type: Article | 2019

Recent developments in genetic/genomic medicine - Rachel Horton and Anneke Lucassen
Type: Article | 2019

Unpacking the concept of a genomic result - Rachel Horton, Anneke Lucassen and Angela Fenwick
Type: Letter | 2019

Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis - James F. Howard, Vera Bril, Ted M. Burns, Renato Mantegazza, Malgorzata Bilinska, Andrzej Szczudlik, Said Beydoun, Francisco Javier Rodriguez De Rivera Garrido, Fredrick Piehl, Mariarosa Rottoli, Phillip Van Damme, Tuan Vu, Amelia Evoli, Miriam Freimer, Tahseen Mozaffar, E. Sally Ward, Torsten Dreier, Peter Ulrichts, Katrien Verschueren, Antonio Guglietta, Hans de Haard, Nicolas Leupin and Jan J.G.M. Verschuuren
Type: Article | 2019 | Item not available on this server.

AAV2/8 anti-angiogenic gene therapy using single-chain antibodies inhibits murine choroidal neovascularization - Christopher P Hughes, Neil MJ O'Flynn, Maureen Gatherer, Michelle E McClements, Jennifer Scott, Robert E. MacLaren, Srinivas V Goverdhan, Martin Glennie and Andrew Lotery
Type: Article | 2019

Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus - Maria Victoria Humbert, Alexandra Jackson, Christian M. Orr, Ivo Tews and Myron Christodoulides
Type: Article | 2019

The NeST (neoadjuvant systemic therapy in breast cancer) study - Protocol for a prospective multi-centre cohort study to assess the current utilization and short-term outcomes of neoadjuvant systemic therapies in breast cancer - G.W. Irwin, F. Bannon, C.E. Coles, E. Copson, R.I. Cutress, R.V. Dave, M. Grayson, C. Holcombe, S. Irshad, C. O'Brien, R.L. O'Connell, C. Palmieri, A.M. Shaaban, N. Sharma, J. Singh, I. Whitehead, S. Potter and S.A. McIntosh
Type: Article | 2019

Role of obinutuzumab exposure on clinical outcome of follicular lymphoma treated with first-line immunochemotherapy - Candice Jamois, Ekaterina Gibiansky, Leonid Gibiansky, Vincent Buchheit, Denis Sahin, Guillaume Cartron, Robert Marcus, Wolfgang Hiddemann, John F. Seymour, Jonathan C. Strefford, Chantal E. Hargreaves, Georgina Meneses-Lorente, Nicolas Frey and Günter Fingerle-Rowson
Type: Article | 2019

Systematic review of somatic mutations in splenic marginal zone lymphoma - Carolina Jaramillo Oquendo, Helen Parker, David G. Oscier, Sarah Ennis, Jane Gibson and Jonathan Strefford
Type: Article | 2019

Aspirin as an adjuvant treatment for cancer: feasibility results from the Add-Aspirin randomised trial - Nalinie Joharatnam-Hogan, Fay Cafferty, Richard Hubner, Daniel Swinson, Sharmila Sothi, Kamalnayan Gupta, Stephen Falk, Kinnari Patel, Nicola Warner, Victoria Kunene, Sam Rowley, Komel Khabra, Tim Underwood, Janusz Jankowski, John Bridgewater, Anne Crossley, Verity Henson, Lindy Berkman, Duncan Gilbert, Howard Kynaston, Alistair Ring, David Cameron, Farhat Din, Janet Graham, Timothy Iveson, Richard Adams, Anne Thomas, Richard Wilson, C.S. Pramesh and Ruth Langley
Type: Article | 2019

Engineering a HER2-specific antibody–drug conjugate to increase lysosomal delivery and therapeutic efficacy - Jeffrey C. Kang, Wei Sun, Priyanka Khare, Mostafa Karimi, Xiaoli Wang, Yang Shen, Raimund Ober and E. Sally Ward
Type: Article | 2019

ERAP1 allotypes impact the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection - Janine Kemming, Emma Reeves, Katja Nitschke, Vanessa Widmeier, Florian Emmerich, Tobias Hermle, Emma Gostick, Andreas Walker, Jorg Timm, David Price, Maike Hofmann, Robert Thimme, Edward James and Christophe Neumann-Haefelin
Type: Article | 2019

Mutations in RPSA and NKX2-3 link development of the spleen and intestinal vasculature - Chantal Kerkhofs, Servi J C Stevens, Saul N Faust, William Rae, Anthony P Williams, Peter Wurm, Rune Østern, Paul Fockens, Christiane Würfel, Martin Laass, Freddy Kokke, Alexander P A Stegmann and Han G Brunner
Type: Article | 2019

Generation of functional hepatocyte 3D discoids in an acoustofluidic bioreactor - Mogib Khedr, Walid, Mohamed Messaoudi, Umesh Jonnalagadda, Ahmed Abdelmotelb, Peter Glynne-Jones, Martyn Hill, Salim I Khakoo and Mohammad Abu Hilal
Type: Article | 2019

A validated PROM in genetic counselling: the psychometric properties of the Dutch version of the Genetic Counselling Outcome Scale - Wrm Krijnen, Margreet G.E.M. Ausems, Nine V.A.M. Knoers, Mary Velthuizen, Erwin Birnie, Irene M. Van Langen, Anneke Lucassen and Adelita V. Ranchor
Type: Article | 2019 | Item not available on this server.

Perpetual sedimentation for the continuous delivery of particulate suspensions - Simon Lane, Jonathan Butement, Jack Harrington, Timothy Underwood, John Shrimpton and Jonathan West
Type: Article | 2019

Type: Review | 2019 | Item not available on this server.

Immuno-oncology for surgeons - S.L. Lee, A. Al-Shamkhani and A. Mirnezami
Type: Article | 2019

Preclinical evaluation of a novel SHIP1 phosphatase activator for inhibition of PI3K signaling in malignant B-cells - Elizabeth A. Lemm, Beatriz Valle-Argos, Lindsay D. Smith, Johanna Richter, Yohannes Gebreselassie, Mathew J. Carter, Jana Karolova, Michael Svaton, Karel Helman, Nicola J. Weston-Bell, Laura Karydis, Chris T. Williamson, Georg Lenz, Jeremy Pettigrew, Curtis Harwig, Freda K. Stevenson, Mark Cragg, Francesco Forconi, Andrew J. Steele, Jennifer Cross, Lloyd Mackenzie, Pavel Klener and Graham Packham
Type: Article | 2019

Developing pedagogy for 'Big Qual' methods: Teaching how to analyse large volumes of secondary qualitative data - Sarah Lewthwaite, Susie Weller, Lynn Jamieson, Rosalind Edwards and Melanie Nind
Type: Monograph | 2019 | National Centre for Research Methods | Item not available on this server.

Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core - G. Liegl, M. A. Petersen, M. Groenvold, N. K. Aaronson, A. Costantini, P. M. Fayers, B. Holzner, C. D. Johnson, G. Kemmler, K. A. Tomaszewski, A. Waldmann, T. E. Young, M. Rose and S. Nolte
Type: Article | 2019

Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta - Emma M Lofthouse, Christopher Torrens, Antigoni Manousopoulou, Monica Nahar, Jane K. Cleal, Ita M O'Kelly, Bram G. Sengers, Spiros D. Garbis and Rohan M Lewis
Type: Article | 2019

Options for first line therapy of Hodgkin lymphoma - Jemma Longley and Peter W.M. Johnson
Type: Article | 2019

Type: Article | 2019

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope - Bruce J. MacLachlan, Garry Dolton, Athanasios Papakyriakou, Alexander Greenshields-Watson, Georgina H. Mason, Andrea Schauenburg, Matthieu Besneux, Barbara Szomolay, Tim Elliott, Andrew K. Sewell, Awen Gallimore, Pierre Rizkallah, David K. Cole and Andrew Godkin
Type: Article | 2019

Type: Article | 2019 | Item not available on this server.

Potential for diagnosis of infectious disease from the 100,000 Genomes Project Metagenomic Dataset: recommendations for reporting results - G. Magiorkinis, P.C. Matthews, S.E. Wallace, K. Jeffery, K. Dunbar, R. Tedder, J.L. Mbisa, B. Hannigan, E. Vayena, P. Simmonds, D.S. Brewer, A. Gihawi, G. Rallapalli, L. Lahnstein, T. Fowler, C. Patch, F. Maleady-Crowe, A. Lucassen and C. Cooper
Type: Letter | 2019

Early oxidative stress response in patients with severe aortic stenosis undergoing transcatheter and surgical aortic valve replacement - a transatlantic study - Michael Mahmoudi, Juan Guillermo Gormaz, Marcia Erazo, Michael Howard, Cristina Baeza, Martin Feelisch, Nicholas Curzen, Bartosz Olechowski, Bernadette Fernandez, Magdalena Minnion, Monika Mikus-Lelinska, Mia S. Meiss, Laurie Lau, Nicolas Valls, Abraham Gajardo, Amy Rivotta, Rodrigo Carrasco, Gabriel Cavada, Maria Jesus Vergara and Gabriel Maluenda
Type: Article | 2019

Type: Thesis | 2019 | University of Southampton

Type: Book Section | 2019 | John Wiley | Item availability restricted.

Marine omega-3 fatty acid supplementation in non-alcoholic fatty liver disease: plasma proteomics in the randomized WELCOME* trial - Antigoni Manousopoulou, Eleonora Scorletti, Deborah Smith, Jie Teng, Miltiadis Fotopoulos, Theodoros I. Roumeliotis, Geraldine F. Clough, Philip C. Calder, Christopher D. Byrne and Spiros D. Garbis
Type: Article | 2019

Tumor downstaging as an intermediate endpoint to assess the activity of neoadjuvant systemic therapy in patients with muscle-invasive bladder cancer - Alberto Martini, Rachel Jia, Bart S. Ferket, Nikhil Waingankar, Elizabeth R. Plimack, Simon J. Crabb, Lauren C. Harshman, Evan Y. Yu, Thomas Powles, Jonathan E. Rosenberg, Sumanta K. Pal, Ulka N. Vaishampayan, Andrea Necchi, N. Peter Wiklund, Reza Mehrazin, Madhu Mazumdar, John P. Sfakianos and Matthew D. Galsky
Type: Article | 2019 | Item not available on this server.

Polygenic risk scores for prediction of breast cancer and breast cancer subtypes - Nasim Mavaddat, Lorraine Durcan and Kyriaki Michailidou
Type: Article | 2019

Population-based observational study of acute pancreatitis in southern England - Alexander Mirnezami, Ben Knight, Brendan Moran, Fergus Noble, Graham Branagan, John Primrose, Katherine Pearson, Malcolm West, Nathan Curtis, Phil Pucher, Ramsey Cuttress, Sian Pugh and Tim Underwood
Type: Article | 2019 | Item availability restricted.

PD-1/PD-L1 blockade in paediatric cancers: What does the future hold? - Julia Moreno-Vicente, Stephen A. Beers and Juliet C. Gray
Type: Review | 2019 | Item not available on this server.

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma - Thanos P. Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Juliane Perner, Matteo Cereda, Jesper Lagergren, Michael Howell, Christopher Yau, Rebecca C. Fitzgerald, Paola Scaffidi and Francesca D. Ciccarelli
Type: Article | 2019

Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen b-receptors - Theodoros Moysiadis, Panagiotis Baliakas, Davide Rossi, Mark Catherwood, Jonathan Strefford, Julio Delgado, Achilles Anagnostopoulos, Chrysoula Belessi, Niki Stavroyianni, Sarka Pospisilova, David G Oscier, Gianluca Gaidano, Elias Campo, Richard Rosenquist, Paolo Ghia and Kostas Stamatopoulos
Type: Letter | 2019 | Item availability restricted.

General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States - S. Nolte, G. Liegl, M. A. Petersen, N. K. Aaronson, A. Costantini, P. M. Fayers, M. Groenvold, B. Holzner, C. D. Johnson, G. Kemmler, K. A. Tomaszewski, A. Waldmann, T. E. Young and M. Rose
Type: Article | 2019

A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping - Luke O'Gorman, Chelsea Norman, Luke Michaels, Tutte Newall, Andrew H. Crosby, Christopher Mattocks, Angela Cree, Andrew Lotery, Emma L. Baple, Arjuna Ratnayaka, Diana Baralle, Helena Lee, Daniel Osborne, Fatima Shawkat, Jane Gibson, Sarah Ennis and Jay E. Self
Type: Article | 2019

Antigenic targets for the immunotherapy of Acute Myeloid Leukaemia - Kim Orchard, Ghalaza Khan and Barbara Gwinn
Type: Article | 2019

Breast cancer in patients with germline TP53 pathogenic variants have typical tumour characteristics: the Cohort study of TP53 carrier early onset breast cancer (COPE study) - Katie Packwood, Guy Martland, Matthew Sommerlad, Emily Shaw, Karwan Moutasim, Gareth Thomas, Adrian Bateman, Louise Jones, Linda Haywood, D. Gareth Evans, Jillian Birch, Ohud Abdullah Alsalmi, Alex Henderson, Nicola Poplawski and Diana Eccles
Type: Article | 2019

Eggplant domestication: pervasive gene flow, feralization, and transcriptomic divergence - Anna Page, Jane Gibson, Rachel S. Meyer and Mark Chapman
Type: Article | 2019

A hidden Markov model approach to characterizing the photo-switching behaviour of fluorophores - Lekha Patel, Nils Gustafsson, Yu Lin, Raimund Ober, Ricardo Henriques and Edward Cohen
Type: Article | 2019

Focal skeletal FDG uptake indicates poor prognosis in cHL regardless of extent and first-line chemotherapy - Mette A. Pedersen, Lars C. Gormsen, Peter Kamper, Cecilia Wassberg, Maja D. Andersen, Alexander L. d'Amore, Sally F. Barrington, Peter Johnson, Stephen Hamilton-Dutoit, Rose Marie Amini, Gunilla Enblad, Daniel Molin and Francesco d'Amore
Type: Article | 2019

The use of digital pathology and image analysis in clinical trials - Robert Pell, Karin Oien, Max Robinson, Helen Pitman, Nasir Rajpoot, Jens Rittscher, David Snead and Clare Verrill
Type: Review | 2019

Recent advances in the molecular landscape of lung neuroendocrine tumors - Giuseppe Pelosi, Fabrizio Bianchi, Paul Hofman, Linda Pattini, Philipp Ströbel, Fiorella Calabrese, Salma Naheed, Chloe Holden, Judith Cave, Hanibal Bohnenberger, Helen Dinter, Sergio Harari, Adriana Albini, Angelica Sonzogni, Mauro Papotti, Marco Volante and Christian H. Ottensmeier
Type: Review | 2019

Author correction: High-dose chemotherapy and autologous stem cell transplantation in enteropathy-associated and other aggressive T-cell lymphomas: a UK NCRI/Cancer Research UK Phase II Study (Bone Marrow Transplantation, (2019), 54, 3, (465-468), 10.1038/s41409-018-0294-2) - Elizabeth H. Phillips, Michelle M. Lannon, Andre Lopes, Humra Chadwick, Gail Jones, Michal Sieniawski, Andrew Davies, Katrina Wood, Laura Clifton-Hadley, Paul Smith, Anthony Lawrie, Nick Chadwick and Anne L. Lennard
Type: Letter | 2019 | Item not available on this server.

High-dose chemotherapy and autologous stem cell transplantation in enteropathy-associated and other aggressive T-cell lymphomas: a UK NCRI/Cancer Research UK Phase II Study - Elizabeth H. Phillips, Michelle M. Lannon, Andre Lopes, Humra Chadwick, Gail Jones, Michal Sieniawski, Andrew Davies, Katrina Wood, Laura Clifton-Hadley, Paul Smith, Anthony Lawrie, Nick Chadwick and Anne L. Lennard
Type: Article | 2019 | Item not available on this server.

Na+/K+-pump and neurotransmitter membrane receptors - Arkady S. Pivovarov, Fernando Calahorro and Robert J. Walker
Type: Review | 2019

Expanded carrier screening for autosomal recessive conditions in health care: arguments for a couple-based approach and examination of couples' views - Mirjam Plantinga, Erwin Birnie, Juliette Schuurmans, Anne H. Buitenhuis, Elise Boersma, Anneke M. Lucassen, Marian A. Verkerk, Irene M. van Langen and Adelita V. Ranchor
Type: Article | 2019

Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study - Shelley Potter, Elizabeth J. Conroy, Ramsey Cutress, Paula R. Williamson, Lisa J. Whisker, Steven Thrush, Joanna M. Skillman, Nicola Barnes, Senthurun Mylvaganam, Elisabeth Teasdale, Abhilash Jain, Matthew D. Gardiner, Jane M. Blazeby and Christopher Holcombe
Type: Article | 2019

Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial - Thomas Powles, Mark Kockx, Alejo Rodriguez-Vida, Ignacio Duran, Simon J. Crabb, Michiel S Van Der Heijden, Bernadett Szabados, Albert Font Pous, Gwenaelle Gravis, Urbano Anido Herranz, Andrew Protheroe, Alain Ravaud, Denis Maillet, Maria Jose Mendez, Cristina Suarez, Mark Linch, Aaron Prendergast, Pieter-Jan van Dam, Diana Stanoeva, Sofie Daelemans, Sanjeev Mariathasan, Joy S. Tea, Kelly Mousa, Romain Banchereau and Daniel Castellano
Type: Letter | 2019

Network mapping of molecular biomarkers influencing radiation response in rectal cancer - Liam Poynter, Dieter Galea, Kirill Veselkov, Alexander Mirnezami, James Kinross, Jeremy Nicholson, Zoltán Takáts, Ara Darzi and Reza Mirnezami
Type: Review | 2019

Type: Article | 2019

Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study - John N. Primrose, Richard P. Fox, Daniel H. Palmer, Hassan Z. Malik, Raj Prasad, Darius Mirza, Alan Anthony, Pippa Corrie, Stephen Falk, Meg Finch-Jones, Harpreet Wasan, Paul Ross, Lucy Wall, Jonathan Wadsley, Jeff T.R. Evans, Deborah Stocken, Raaj Praseedom, Yuk Ting Ma, Brian Davidson, John P. Neoptolemos, Tim Iveson, James Raftery, Shihua Zhu, David Cunningham, O. James Garden, Clive Stubbs, Juan W. Valle and John Bridgewater
Type: Article | 2019

Training and accreditation standards for pathologists undertaking clinical trial work - Gabrielle Rees, Manuel Salto-Tellez, Jessica L. Lee, Karin Oien, Clare Verrill, Alex Freeman, Ilaria Mirabile and Nicholas P. West
Type: Article | 2019

HPV epitope processing differences correlate with ERAP1 allotype and extent of CD8+ T cell tumor infiltration in OPSCC - Emma Reeves, Oliver Wood, Christian Ottensmeier, Emma King, Gareth Thomas, Timothy Elliott and Edward James
Type: Article | 2019

Type: Article | 2019

Ex-vivo signal transduction studies in chronic lymphocytic leukemia - Karly Rai Rogers-Broadway, Laura I. Karydis, Rachel C. Dobson and Andrew J. Steele
Type: Book Section | 2019 | Humana Press Inc. | Item not available on this server.

Cyclophosphamide enhances cancer antibody immunotherapy in the resistant bone marrow niche by modulating macrophage FcγR expression - Ali Roghanian, Guangan Hu, Christopher Fraser, Maneesh Singh, Russell Foxall, Matthew J. Meyer, Emma Lees, Heather Huet, Martin Glennie, Stephen Beers, Sean Lim, Margaret Ashton-Key, Stephen Thirdborough, Mark Cragg and Jianzhu Chen
Type: Article | 2019

Development and validation of a model to predict outcomes of colon cancer surveillance - Johnie Rose, Laura Homa, Chung Yin Kong, Gregory Cooper, Michael Kattan, Bridget Ermlich, Jeffrey Meyers, John Primrose, Sian Pugh, Bethany Shinkins, Uriel Kim and Neal Meropol
Type: Article | 2019

Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease - Peter Rudge, Zane Jaunmuktane, Harpreet Hyare, Matthew Ellis, Martin Koltzenburg, John Collinge, Sebastian Brandner and Simon Mead
Type: Article | 2019

Super-resolution fight club: Assessment of 2D & 3D single-molecule localization microscopy software - Daniel Sage, Thanh Pham, Hazen Babcock, Tomas Lukes, Thomas Pengo, Jerry Chao, Ramraj Velmurugan, Alex Herbert, Anurag Agrawal, Silvia Colabrese, Ann Wheeler, Anna Archetti, Bernd Rieger, Raimund Ober, Guy M. Hagen, Jean-Baptiste Sibarita, Jonas Ries, Ricardo Henriques, Michael Unser and Seamus Holden
Type: Article | 2019

When three isn't a crowd: a digyny concept for treatment-resistant, near-triploid human cancers - Kristine Salmina, Bogdan I. Gerashchenko, Michael Hausmann, Ninel M. Vainshelbaum, Pawel Zayakin, Juris Erenpreiss, Talivaldis Freivalds, Mark S. Cragg and Jekaterina Erenpreisa
Type: Article | 2019

The cancer aneuploidy paradox: In the light of evolution - Kristine Salmina, Anda Huna, Martins Kalejs, Dace Pjanova, Harry Scherthan, Mark Cragg and Jekaterina Erenpreisa
Type: Article | 2019

Type: Article | 2019

Oncogenic osteomalacia and metastatic breast cancer: a case report and review of the literature - Constantinos Savva, Jason Adhikaree, Srinivasan Madhusudan and Kamal Chokkalingam
Type: Article | 2019

Type: Article | 2019

Stratification of asthma phenotypes by airway proteomic signatures - James P.R. Schofield, Dominic Burg, Ben Nicholas, Fabio Strazzeri, Joost Brandsma, Doroteya Staykova, Caterina Folisi, Aruna T. Bansal, Yang Xian, Yike Guo, Anthony Rowe, Julie Corfield, Susan Wilson, Jonathan Ward, Rene Lutter, Dominick E. Shaw, Per S. Bakke, Massimo Caruso, Sven-erik Dahlen, Stephen J. Fowler, Ildikó Horváth, Peter Howarth, Norbert Krug, Paolo Montuschi, Marek Sanak, Thomas Sandström, Kai Sun, Ioannis Pandis, John Riley, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, Ana R. Sousa, Ian M. Adcock, Kian Fan Chung, Peter J. Sterk, Paul J. Skipp and Ratko Djukanović
Type: Article | 2019

GP-provided couple-based expanded preconception carrier screening in the Dutch general population: who accepts the test-offer and why? - Juliette Schuurmans, Erwin Birnie, Adelita V. Ranchor, Kristin M. Abbott, Angela Fenwick, Anneke Lucassen, Marjolein Y. Berger, Marian A. Verkerk, Irene M. Van Langen and Mirjam Plantinga
Type: Article | 2019

Feasibility of couple-based expanded carrier screening offered by general practitioners - Juliette Schuurmans, Erwin Birnie, L.M. van den Heuvel, Mirjam Plantinga, Anneke Lucassen, D.M. van der Kolk, K.M. abbott, Adelita V. Ranchor, A.D. Diemers and Irene M. Van Langen
Type: Article | 2019

Association of early disease progression and very poor survival in the GALLIUM study in follicular lymphoma: benefit of obinutuzumab in reducing the rate of early progression - John F. Seymour, Robert Marcus, Andrew Davies, Eve Gallop-Evans, Andrew Grigg, Andrew Haynes, Michael Herold, Thomas Illmer, Herman Nilsson-Ehle, Martin Sökler, Ulrich Dünzinger, Tina Nielsen, Aino Launonen and Wolfgang Hiddemann
Type: Article | 2019

Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma - Bracha Shraibman, Eilon Barnea, Dganit Melamed Kadosh, Yael Haimovich, Gleb Slobodin, Itzhak Rosner, Carlos López-Larrea, Norbert Hilf, Sabrina Kuttruff, Colette Song, Cedrik Britten, John Castle, Sebastian Kreiter, Katrin Frenzel, Marcos Tatagiba, Ghazaleh Tabatabai, Pierre Yves Dietrich, Valérie Dutoit, Wolfgang Wick, Michael Platten, Frank Winkler, Andreas Von Deimling, Judith Kroep, Juan Sahuquillo, Francisco Martinez-Ricarte, Jordi Rodon, Ulrik Lassen, Christian Ottensmeier, Sjoerd H. Van der Burg, Per Thor Straten, Hans Skovgaard Poulsen, Berta Ponsati, Hideho Okada, Hans Georg Rammensee, Ugur Sahin, Harpreet Singh and Arie Admon
Type: Article | 2019 | Item not available on this server.

Adjuvant therapy for resected biliary tract cancer: ASCO Clinical Practice Guideline - Rachna T. Shroff, Erin B. Kennedy, Melinda Bachini, Tanios Bekaii-Saab, Christopher Crane, Julien Edeline, Anthony El-Khoueiry, Mary Feng, Matthew H.G. Katz, John Primrose, Heloisa P. Soares, Juan Valle and Shishir K. Maithel
Type: Article | 2019

Type: Article | 2019

BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia - Lindsay Smith, Annabel, Rachel Minton, Matthew Blunt, Laura Karydis, David Dutton, Karly-rai Rogers-broadway, Rachel Dobson, Rena Liu, Faith Norster, Elizabeth Hogg, Margaret Ashton-Key, Jonathan Strefford, Li Jia, Dimitar Efremov, Helgason G. Vignir, Peter Johnson, Freda Stevenson, Francesco Forconi, Mark Cragg, David Tumbarello, Graham Packham and Andrew Steele
Type: Article | 2019

Improved multiplex immunohistochemistry for immune microenvironment evaluation of mouse formalin-fixed, paraffin-embedded tissues - Noah Sorrelle, Debolina Ganguly, Adrian T.A. Dominguez, Yuqing Zhang, Huocong Huang, Lekh N. Dahal, Natalie Burton, Arturas Ziemys and Rolf A. Brekken
Type: Article | 2019 | Item not available on this server.

Discrepancies in the tumor microenvironment of spontaneous and orthotopic murine models of pancreatic cancer uncover a new immunostimulatory phenotype for B cells - Sarah Spear, Juliana B. Candido, Jacqueline R. McDermott, Cristina Ghirelli, Eleni Maniati, Stephen A. Beers, Frances R. Balkwill, Hemant M. Kocher and Melania Capasso
Type: Article | 2019

Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC - Rahul Sreekumar, Muhammad Emaduddin, Hajir Al-Saihati, Karwan Moutasim, James Chan, Marcello Spampinato, Rahul Bhome, Ho Ming Yuen, Claudia Mescoli, Alessandro Vitale, Umberto Cillo, Massimo Rugge, John Primrose, Mohammad Abu Hilal, Stephen Thirdborough, Eugene Tulchinsky, Gareth Thomas, Alex Mirnezami and A Emre Sayan
Type: Article | 2019

Type: Book Section | 2019 | Humana Press | Item not available on this server.

A unique genome in EBV-positive BL - Jonathan C. Strefford and David G. Oscier
Type: Letter | 2019 | Item availability restricted.

A cost-effectiveness analysis of multigene testing for all patients with breast cancer - Li Sun, Adam Brentnall, Shreeya Patel, Diana S. M. Buist, Erin J. A. Bowles, D. Gareth R. Evans, Diana Eccles, John Hopper, Shuai Li, Melissa Southey, Stephen Duffy, Jack Cuzick, Isabel Dos Santos Silva, Alec Miners, Zia Sadique, Li Yang, Rosa Legood and Ranjit Manchanda
Type: Article | 2019

Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma - K. Tariq, J.P.R. Schofield, B.L. Nicholas, D. Burg, J. Brandsma, A.T. Bansal, S.J. Wilson, R. Lutter, S.J. Fowler, M. Bakke, M. Caruso, B. Dahlen, I. Horvath, N. Krug, P. Montuschi, M. Sanak, T. Sandstrom, T. Geiser, I. Pandis, A.R. Sousa, I.M. Adcock, D.E. Shaw, C. Auffray, P.H. Howarth, P.J. Sterk, K.F. Chung, P.J. Skipp, B. Dimitrov and R. Djukanovic
Type: Article | 2019

Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma - Richard Turkington, Laura Knight, Jaine K. Blayney, Maria Secrier, Rosalie Douglas, Eileen E. Parkes, Eilis K. Sutton, Leanne Stevenson, Damien McManus, Sophia Halliday, Andrena M. McCavigan, Gemma E. Logan, Steven M. Walker, Christopher J. Steele, Juliane Perner, Jan Bornschein, Shona MacRae, Ahmed Miremadi, Eamon McCarron, stephen McQuaid, Ken Arthur, Jacqueline James, Martin Eatock, J. Robert O'Neill, Fergus Noble, Timothy Underwood, D. Paul Harkin, Manuel Salto-Tellez, Rebecca C. Fitzgerald and Richard D. Kennedy
Type: Article | 2019

Type: Article | 2019 | Item not available on this server.

Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering - Andres Vallejo Pulido, James Davies, Amit Grover, Ching-Hsuan Tsai, Robert Jepras, Marta Polak and Jonathan West
Type: Monograph | 2019 | Biorxiv | Item not available on this server.

An optimised tissue disaggregation and data processing pipeline for characterising fibroblast phenotypes using single-cell RNA sequencing - Sara Waise, Rachel Parker, Matthew Rose-Zerilli, David Layfield, Oliver Wood, Jonathon West, Christian Ottensmeier, Gareth Thomas and Christopher Hanley
Type: Article | 2019

Durable response with single-agent acalabrutinib in patients with relapsed or refractory mantle cell lymphoma - Michael Wang, Simon Rule, Pier Luigi Zinzani, Andre Goy, Olivier Casasnovas, Stephen D. Smith, Gandhi Damaj, Jeanette K. Doorduijn, Thierry Lamy, Franck Morschhauser, Carlos Panizo, Bijal Shah, Andrew Davies, Richard Eek, Jehan Dupuis, Eric Jacobsen, Arnon P. Kater, Steven Le Gouill, Lucie Oberic, Tadeusz Robak, Preetesh Jain, Melanie M. Frigault, Raquel Izumi, Dorothy Nguyen, Priti Patel, Ming Yin and Monika Długosz-Danecka
Type: Letter | 2019

Type: Book Section | 2019 | Octaedro | Item not available on this server.

Type: Dataset | 2019 | University of Leeds | Item not available on this server.

Type: Monograph | 2019 | National Centre for Research Methods | Item not available on this server.

Search strategies: analytic searching across multiple datasets and within combined sources - Susan Weller, Rosalind Edwards, Lynn Jamieson and Emma Davidson
Type: Book Section | 2019 | SAGE Publications | Item not available on this server.

Selecting data sets to create new assemblages - Susie Weller, Rosalind Edwards, Lynn Jamieson and Emma Davidson
Type: Article | 2019 | Item not available on this server.

Type: Dataset | 2019 | github.io | Item not available on this server.

Exercise prehabilitation may lead to augmented tumor regression following neoadjuvant chemoradiotherapy in locally advanced rectal cancer - M. A. West, R. Astin, H. E. Moyses, J. Cave, D. White, D. Z.H. Levett, A. Bates, G. Brown, M. P.W. Grocott and S. Jack
Type: Article | 2019

Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery - Malcolm West, David P.J. van Dijk, Frederick Gleadowe, Thomas Reeves, John Primrose, Mohammad Abu Hilal, Mark Edwards, Sandy Jack, Sander S.S. Rensen, Michael Grocott, Denny Levett and Steven W. M. Olde Damink
Type: Article | 2019

Drivers of year-to-year variation in exacerbation frequency of COPD: analysis of the AERIS cohort - Tom M.A. Wilkinson, Emmanuel Aris, Simon C. Bourne, Stuart C. Clarke, M. Peeters, Thierry G. Pascal, Laura Taddei, Andrew C Tuck, Viktoriya L. Kim, Kristoffer Ostridge, Karl J. Staples, Nicholas, Paul Williams, Anthony P. Williams, Stephen A. Wootton and Jeanne-Marie Devaster
Type: Article | 2019

A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery - Michael S.J. Wilson, Natalie S. Blencowe, Christopher Boyle, Stephen R. Knight, Russell Petty, Ravi S. Vohra and Timothy Underwood
Type: Article | 2019 | Item not available on this server.

Hepatic resection following selective internal radiation therapy for colorectal cancer metastases in the FOXFIRE clinical trial: Clinical outcomes and distribution of microspheres - Helen Winter, Joseph Rassam, Pradeep Virdee, Rob Goldin, Priyankaa Pitcheshwar, Klara Weaver, John Primrose, David Berry, Harpreet Wasan and Ricky Sharma
Type: Article | 2019

Clinical significance of DNA methylation in chronic lymphocytic leukaemia patients: results from three UK clinical trials - Tomasz Wojdacz, Harindra E. Amarasinghe, Latha Kadalayil, Alice Beattie, Jade Forster, Stuart Blakemore, Helen Parker, Dean Bryant, Marta Larrayoz, Ruth Clifford, Pauline Robbe, Zadie Davis, Monica Else, Dena R. Howard, Basile Stamatopoulos, Andrew Steele, Richard Rosenquist, Andrew Collins, Andrew Pettitt, Peter Hillmen, Christoph Plass, Anna Schuh, Daniel Catovsky, David G Oscier, Matthew Rose-Zerilli, Christopher C. Oakes and Jonathan Strefford
Type: Article | 2019

Genomic variant sharing: a position statement - Caroline F. Wright, James S. Ware, Anneke M. Lucassen, Alison Hall, Anna Middleton, Nazneen Rahman, Sian Ellard and Helen V. Firth
Type: Article | 2019

Genomic variant sharing: A position statement [version 2; peer review: 2 approved] - Caroline F. Wright, James S. Ware, Anneke M. Lucassen, Alison Hall, Anna Middleton, Nazneen Rahman, Sian Ellard and Helen V. Firth
Type: Article | 2019 | Item not available on this server.

Phase I study of the novel Enhancer of Zeste Homolog 2 (EZH2) inhibitor GSK2816126 in patients with advanced hematologic and solid tumors - Timothy A. Yap, Jane N. Winter, Lisa Giulino-Roth, Jemma Longley, Juanita Lopez, Jean-Marie Michot, John P. Leonard, Vincent Ribrag, Michael T. McCabe, Caretha L. Creasy, Melissa Stern, Teodora Pene Dumitrescu, Xiaowei Wang, Steve Frey, Jennifer Carver, Thierry Horner, Choon Oh, Ahmed Khaled, Arindam Dhar and Peter W.M. Johnson
Type: Article | 2019

Randomized phase III trial of ibrutinib and rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in non-germinal center B-cell diffuse large B-cell lymphoma - Anas Younes, Laurie H Sehn, Peter Johnson, Pier Luigi Zinzani, Xiaonan Hong, Jun Zhu, Caterina Patti, David Belada, Olga Samoilova, Cheolwon Suh, Sirpa Leppä, Shinya Rai, Mehmet Turgut, Wojciech Jurczak, Matthew C Cheung, Ronit Gurion, Su-Peng Yeh, Andres Lopez-Hernandez, Ulrich Dührsen, Catherine Thieblemont, Carlos Sergio Chiattone, Sriram Balasubramanian, Jodi Carey, Grace Liu, S Martin Shreeve, Steven Sun, Sen Hong Zhuang, Jessica Vermeulen, Louis M Staudt and Wyndham Wilson
Type: Article | 2019 | Item availability restricted.

Type: Dataset | 2019 | University of Southampton

Evaluation and management of incidental gallbladder cancer - Mohammad Y. Zaidi, Ghassan K. Abou-Alfa, Cecilia G. Ethun, Shailesh V. Shrikhande, Mahesh Goel, Bruno Nervi, John Primrose, Juan W. Valle and Shishir K. Maithel
Type: Article | 2019 | Item availability restricted.

Associations with corneal hysteresis in a population cohort: results from 96 010 UK Biobank participants - Bing Zhang, Yusrah Shweikh, Anthony P. Khawaja, John Gallacher, Sarah Bauermeister and Paul J. Foster
Type: Article | 2019 | Item not available on this server.

Mutant IDH sensitizes gliomas to endoplasmic reticulum stress and triggers apoptosis via miR-183-mediated inhibition of Semaphorin 3E - Ying Zhang, Stefan Pusch, James Innes, Kastytis Sidlauskas, Matthew Ellis, Joanne Lau, Tedani El-Hassan, Natasha Aley, Francesca Launchbury, Angela Richard-Loendt, Jasper deBoer, Sheng Chen, Lei Wang, Andreas von Deimling, Ningning Li and Sebastian Brandner
Type: Article | 2019 | Item not available on this server.

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis - Joep J. de Jong, Yang Liu, A. Gordon Robertson, Roland Seiler, Clarice S. Groeneveld, Michiel S. van der Heijden, Jonathan L. Wright, James Douglas, Marc Dall'Era, Simon J. Crabb, Bas W.G. van Rhijn, Kim E.M. van Kessel, Elai Davicioni, Mauro A.A. Castro, Yair Lotan, Ellen C. Zwarthoff, Peter C. Black, Joost L. Boormans and Ewan A. Gibb
Type: Article | 2019

Costs and quality of life in a randomized trial comparing minimally invasive and open distal pancreatectomy (LEOPARD trial) - J. van Hilst, E.A. Strating, T. de Rooij, F. Daams, S. Festen, B. Groot Koerkamp, J.M. Klaase, M. Luyer, M.G. Dijkgraaf and M.G. Besselink
Type: Article | 2019

Thoracic muscle radiation attenuation for the prediction of postoperative pneumonia following partial hepatectomy for colorectal metastasis - Gregory van der Kroft, David P.J. van Dijk, Sander S.S. Rensen, Frank H. Van Tiel, Bianca de Greef, Malcolm West, Kristoffer Ostridge, Cornelis H. C. Dejong, Ulf P. Neumann and Steven W. M. Olde Damink
Type: Article | 2019

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