The University of Southampton
University of Southampton Institutional Repository

Items where Division is "Faculties (pre 2018 reorg) > Faculty of Medicine (pre 2018 reorg) > Clinical & Experimental Sciences (pre 2018 reorg)
Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences > Clinical & Experimental Sciences (pre 2018 reorg)
Clinical and Experimental Sciences > Clinical & Experimental Sciences (pre 2018 reorg)" and Year is 2017

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: No Grouping | Authors/Creators | Item Type
Number of items: 317.

Article

Novel presenting phenotype in a child with autosomal dominant Best's vitelliform macular dystrophy - Yasmine F. Abdalla, Gabriella De Salvo, Ahmad Elsahn and James E. Self
Type: Article | 2017

Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation - Parisa Aghagolzadeh, Ramin Radpour, Matthias Bachtler, Harry van Goor, Edward R. Smith, Adam Lister, Alex Odermatt, Martin Feelisch and Andreas Pasch
Type: Article | 2017

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics - Takaaki Akaike, Tomoaki Ida, Fan-yan Wei, Motohiro Nishida, Yoshito Kumagai, Md. Morshedul Alam, Hideshi Ihara, Tomohiro Sawa, Tetsuro Matsunaga, Shingo Kasamatsu, Akiyuki Nishimura, Masanobu Morita, Kazuhito Tomizawa, Akira Nishimura, Satoshi Watanabe, Kenji Inaba, Hiroshi Shima, Nobuhiro Tanuma, Minkyung Jung, Shigemoto Fujii, Yasuo Watanabe, Masaki Ohmuraya, Péter Nagy, Martin Feelisch, Jon M. Fukuto and Hozumi Motohashi
Type: Article | 2017

Honey is potentially effective in the treatment of atopic dermatitis: clinical and mechanistic studies - Abdullah A. Alangari, Keith Morris, Bashir El Wilid, Laurie Lau, Ken Jones, Rose Cooper and Rowena Jenkins
Type: Article | 2017

Individualizing duration of antibiotic therapy in community-acquired pneumonia - Stefano Aliberti, Julio Ramirez, Fabio Giuliani, Timothy Wiemken, Giovanni Sotgiu, Sara Tedeschi, Manuela Carugati, Vincenzo Valenti, Marco Marchioni, Marco Camera, Roberto Piro, Manuela Del Forno, Giuseppe Milani, Paola Faverio, Luca Richeldi, Martina Deotto, Massimiliano Villani, Antonio Voza, Eleonora Tobaldini, Mauro Bernardi, Andrea Bellone, Matteo Bassetti and Francesco Blasi
Type: Article | 2017 | Item not available on this server.

Type: Article | 2017 | Item availability restricted.

What do we know about the inflammasome in humans? - Jay Amin, Delphine Boche and Sonja Rakic
Type: Article | 2017

Multi-generational cohorts in asthma and allergy - Hasan Arshad, Wilfried Karmaus, Hongmei Zhang and John W. Holloway
Type: Article | 2017

Type: Article | 2017

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array - Imelda Barber, Anne Braae, Naomi Clement, Tulsi Patel, Tamar Guetta-Baranes, Keeley Brookes, Christopher Medway, Sally Chappell, Rita Guerreiro, Jose Bras, Dena Hernandez, Andrew Singleton, John Hardy and David Mann
Type: Article | 2017 | Item availability restricted.

Comorbidity and suicidality in patients diagnosed with panic disorder/agoraphobia and major depression - Borkanka Batinic, Goran Opacic, Tijana Ignajatov and David Baldwin
Type: Article | 2017 | Item availability restricted.

Parents' and caregivers' experiences and behaviours when eating out with children with a food hypersensitivity - Fiona M. Began, Julie Barnett, Miriam Barber, Ros Payne, M. Hazel Gowland and Jane S. Lucas
Type: Article | 2017

Validation of a health-related quality of life instrument for primary ciliary dyskinesia (QOL-PCD) - Laura Behan, Margaret W. Leigh, Sharon D. Dell, Audrey Dunn Galvin, Alexandra L. Quittner and Jane S. Lucas
Type: Article | 2017

The patient's experience of primary ciliary dyskinesia: a systematic review - Laura Behan, Bruna Rubbo, Jane Lucas and Audrey Dunn Galvin
Type: Article | 2017

A bioengineered three-dimensional cell culture platform integrated with microfluidics to address antimicrobial resistance in tuberculosis - M.K. Bielecka, L.B. Tezera, R. Zmijan, F. Drobniewski, Xunli Zhang, S. Jayasinghe and P. Elkington
Type: Article | 2017

A severe asthma disease signature from gene expression profiling of peripheral blood from U-BIOPRED cohorts - J. Bigler, M. Boedigheimer, J.P.R. Schofield, P.J. Skipp, J. Corfield, A. Rowe, A.R. Sousa, M. Timour, L. Twehues, X. Hu, G. Roberts, A.A. Welcher, W. Yu, D. Lefaudeuz, B. de Meulder, C Auffrey, K.F. Chung, I.M. Adcock, P.J. Sterk and R. Djukanovic
Type: Article | 2017

Cellular crosstalk between airway epithelial and endothelial cells regulates barrier functions during exposure to double-stranded RNA - Cornelia Blume, Riccardo Reale, Marie Held, Matthew Loxham, Tim Millar, Jane Collins, Emily Swindle, Hywel Morgan and Donna Davies
Type: Article | 2017

Type: Article | 2017

Care pathways for the selection of a biologic in severe asthma - Jean Bousquet, Guy Brusselle, Roland Buhl, William W. Busse, Alvaro A. Cruz, Ratko Djukanovic, Christian Domingo, Nicola A. Hanania, Marc Humbert, Andrew Menzies-Gow, Wanda Phipatanakul, Ulrich Wahn and Michael E. Wechsler
Type: Article | 2017 | Item availability restricted.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma - John A. Bowden, Alan Heckert, Candice Z. Ulmer, Christina M. Jones, Jeremy P. Koelmel, Laila Abdullah, Linda Ahonen, Yazen Alnouti, Aaron M. Armando, John M. Asara, Takeshi Bamba, John R. Barr, Jonas Bergquist, Christoph H. Borchers, Joost Brandsma, Susanne B. Breitkopf, Tomas Cajka, Amaury Cazenave-gassiot, Antonio Checa, Michelle A. Cinel, Romain A. Colas, Serge Cremers, Edward A. Dennis, James E. Evans, Alexander Fauland, Oliver Fiehn, Michael S. Gardner, Timothy J. Garrett, Katherine H. Gotlinger, Jun Han, Yingying Huang, Aveline Huipeng Neo, Tuulia Hyötyläinen, Yoshihiro Izumi, Hongfeng Jiang, Houli Jiang, Jiang Jiang, Maureen Kachman, Reiko Kiyonami, Kristaps Klavins, Christian Klose, Harald C. Köfeler, Johan Kolmert, Therese Koal, Grielof Koster, Zsuzsanna Kuklenyik, Irwin J. Kurland, Michael Leadley, Karen Lin, Krishna Rao Maddipati, Danielle Mcdougall, Peter J. Meikle, Natalie A. Mellett, Cian Monnin, M. Arthur Moseley, Renu Nandakumar, Matej Oresic, Rainey Patterson, David Peake, Jason S. Pierce, Martin Post, Anthony D. Postle, Rebecca Pugh, Yunping Qiu, Oswald Quehenberger, Parsram Ramrup, Jon Rees, Barbara Rembiesa, Denis Reynaud, Mary R. Roth, Susanne Sales, Kai Schuhmann, Michal Laniado Schwartzman, Charles N. Serhan, Andrej Shevchenko, Stephen E. Somerville, Lisa St. John-williams, Michal A. Surma, Hiroaki Takeda, Rhishikesh Thakare, J. Will Thompson, Federico Torta, Alexander Triebl, Martin Trötzmüller, S. J. Kumari Ubhayasekera, Dajana Vuckovic, Jacquelyn M. Weir, Ruth Welti, Markus R. Wenk, Craig E. Wheelock, Libin Yao, Min Yuan, Xueqing Heather Zhao and Senlin Zhou
Type: Article | 2017

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology - Patience T. Brace, Liku B. Tezera, Magdalena K. Bielecka, Toby Mellows, Diana Garay, Shuye Tian, Lucinda Rand, Justin Green, Sanjay Jogai, Andrew J. Steele, Timothy M. Millar, Tilman Sanchez-Elsner, Jon S. Friedland, Christopher G. Proud and Paul T. Elkington
Type: Article | 2017

Acute management of alcohol and other drug problems - Emma Brandish, Christopher Owen and Julia Sinclair
Type: Article | 2017

Type: Article | 2017

Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label, randomised controlled trial - Nathan Brendish, Ahalya K. Malachira, Lawrence Armstrong, Rebecca Houghton, Sandra Aitken, Esther Nyimbili, Sean Ewings, Patrick J. Lillie and Tristan W. Clark
Type: Article | 2017

Type: Article | 2017

Early secretory antigenic target-6 drives matrix metalloproteinase-10 gene expression and secretion in tuberculosis - Sara Brilha, Tarangini Sathyamoorthy, Laura H. Stuttaford, Naomi F. Walker, Robert J. Wilkinson, Shivani Singh, Rachel C. Moores, Paul T. Elkington and Jon S. Friedland
Type: Article | 2017

Microwave therapy for cutaneous human papilloma virus infection - Ian Bristow, Wen Chean Lim, Alvin Lee, Daniel Holbrook, Natalia Savelyeva, Peter Thomson, Christopher Webb, Marta Polak and Michael Ardern-Jones
Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

Functional characterization of a novel 3D model of the epithelial-mesenchymal trophic unit - Fabio Bucchieri, Alessandro Pitruzzella, Alberto Fucarino, Antonella Marino Gammazza, Celeste Bavisotto, Vito Marciano, Massimo Cajozzo, Giorgio Lo Iacono, Roberto Marchese, Giovanni Zummo, Stephen T. Holgate and Donna E. Davies
Type: Article | 2017

Type: Article | 2017

An integrated workflow to assess technical and biological variability of cell population frequencies in human peripheral blood by flow cytometry - Julie G. Burel, Yu Qian, Cecilia Lindestam Arlehamn, Daniela Weiskopf, Jose Zapardiel-Gonzalo, Randy Taplitz, Robert H Gilman, Mayuko Saito, Aruna D de Silva, Pandurangan Vijayanand, Richard H Scheuermann, Alessandro Sette and Bjoern Peters
Type: Article | 2017 | Item not available on this server.

A rapid evidence review of the effectiveness and cost-effectiveness of alcohol control policies: an English perspective - Robyn Burton, Clive Henn, Don Lavoie, Rosanna O'Connor, Clare Perkins, Kate Sweeney, Felix Greaves, Brian Ferguson, Caryl Beynon, Annalisa Belloni, Virginia Musto, John Marsden and Nicholas Sheron
Type: Article | 2017

Type: Article | 2017

Identity in recovery from problematic alcohol Use: A qualitative study of online mutual aid - Sophia, Elaine Chambers, Krysia Canvin, David Baldwin and Julia Sinclair
Type: Article | 2017

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains - Andrew Chancellor, Anna Tocheva, Christopher Cave-Ayland, Liku Bekele Tezera, Andrew White, Juma'a Al Dulayymi, John Bridgeman, Ivo Tews, Susan Wilson, Nikolai Lissin, Marc Tebruegge, Benjamin Marshall, Sally Sharpe, Timothy Elliott, Chris-Kriton Skylaris, Jonathan W. Essex, Mark Baird, Stephan D. Gadola, Paul Elkington and Salah Mansour
Type: Article | 2017

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection - Andrew Chancellor, Andrew White, Anna S. Tocheva, Joe R. Fenn, Mike Dennis, Liku Tezera, Akul Singhania, Timothy Elliott, Marc Tebruegge, Paul Elkington, Stephan D. Gadola, Sally Sharpe and Salah Mansour
Type: Article | 2017

Evaluating the effect of immune cells on the outcome of patients with mesothelioma - Serena J. Chee, Maria Lopez, Toby Mellows, Karwan A. Moutasim, Scott Harris, James, Ian Clarke, Pandurangan Vijayanand, Gareth J. Thomas and Christian H. Ottensmeier
Type: Article | 2017

Epigenetic modification of the CCL5/CCR1/ERK axis enhances glioma targeting in dedifferentiation-reprogrammed BMSCs - Rui Chen, Wayne Yuk-Wai Lee, Xiao Hu Zhang, Jie Ting Zhang, Sien Lin, Liang Liang Xu, Biao Huang, Fu Yuan Yang, Hai Long Liu, Bin Wang, Lai Ling Tsang, Sandrine Willaime-Morawek, Gang Li, Hsiao Chang Chan and Xiaohua Jiang
Type: Article | 2017

Type: Article | 2017

Consistency and variability of DNA methylation in women during puberty, young adulthood, and pregnancy - Su Chen, Nandini Mukherjee, Vimala Janjanam, S. Hasan Arshad, Ramesh J. Kurukulaaratchy, John W. Holloway, Hongmei Zhang and Wilfried Karmaus
Type: Article | 2017

Sorsby fundus dystrophy: a review of pathology and disease mechanisms - David Christensen, Ffion Brown, Angela Cree, J. Arjuna Ratnayaka and Andrew Lotery
Type: Article | 2017

Novel approaches to Neisseria meningitidis vaccine design - Myron Christodoulides and John Heckels
Type: Article | 2017 | Item not available on this server.

Extended three-dimensional rotation invariant local binary patterns - Leonardo Citraro, Sasan Mahmoodi, Angela Darker and Brigitte Vollmer
Type: Article | 2017

Langerhans cells – programmed by the epidermis - Kalum Clayton, Andres F. Vallejo, James Davies, Sofia Sirvent Bernal and Marta E. Polak
Type: Article | 2017

Acute exacerbations in the INPULSIS trials of nintedanib in idiopathic pulmonary fibrosis - Harold R. Collard, Luca Richeldi, Dong Soon Kim, Hiroyuki Taniguchi, Inga Tschoepe, Maurizio Luisetti, Jesse Roman, Gregory Tino, Rozsa Schlenker-Herceg, Christoph Hallmann and Roland M. du Bois
Type: Article | 2017 | Item not available on this server.

Cephalosporin-3’ -diazeniumdiolate NO-donor prodrug PYRRO-C3D enhances azithromycin susceptibility of Non-typeable Haemophilus influenzae biofilms - Samuel A. Collins, Michael J. Kelso, Ardeshir Rineh, Nageshwar R. Yepuri, Janice Coles, Claire L. Jackson, Georgia D. Halladay, Woolf T. Walker, Jeremy S. Webb, Luanne Hall-Stoodley, Gary J. Connett, Martin Feelisch, Saul N. Faust, Jane S.A. Lucas and Raymond N. Allan
Type: Article | 2017

The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis - Franco Conforti, Elizabeth R. Davies, Claire J. Calderwood, Thomas H. Thatcher, Mark G. Jones, David E. Smart, Sumeet Mahajan, Aiman Alzetani, Tom Havelock, Toby M. Maher, Philip L. Molyneaux, Andrew J. Thorley, Teresa D. Tetley, Jane A. Warner, Graham Packham, A. Ganesan, Paul J. Skipp, Benjamin J. Marshall, Luca Richeldi, Patricia J. Sime, Katherine M.A. O'Reilly and Donna E. Davies
Type: Article | 2017

The reactive species interactome: Evolutionary emergence, biological significance, and opportunities for redox metabolomics and personalized medicine - Miriam Margherita Cortese-Krott, Anne Koning, Gunter Georg Kuhnle, Peter Nagy, Christopher Bianco, Andreas Pasch, David A Wink, Jon Fukuto, Alan A Jackson, Harry van Goor, Kenneth R Olson and Martin Feelisch
Type: Article | 2017

Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety - Barbara Costa, Stefano Pini, David S. Baldwin, Derrick Silove, Vijaya Manicavasagar, Marianna Abelli, Fabio Coppedè and Claudia Martini
Type: Article | 2017

The structure of the perivascular compartment in the old canine brain: a case study - Theodore P. Criswell, Matthew MacGregor Sharp, Howard Dobson, Ciara Finucane, Roy O. Weller, Ajay Verma and Roxana O Carare
Type: Article | 2017 | Item not available on this server.

Effects of dietary nitrate on respiratory physiology at high altitude: results from the Xtreme Alps study - Andrew F. Cumpstey, Philip J. Hennis, Edward T. Gilbert-kawai, Bernadette O. Fernandez, Matthieu Poudevigne, Alexandra Cobb, Paula Meale, Kay Mitchell, Helen Moyses, Helmut Pöhnl, Monty G. Mythen, Michael P.w. Grocott, Martin Feelisch and Daniel S. Martin
Type: Article | 2017

Quality of survival and cognitive performance in children treated for medulloblastoma in the PNET 4 randomized controlled trial - Hugo Câmara-Costa, Kim Bull, Colin Kennedy, Andreas Wiener, Gabriele Calaminus, Anika Resch, Virginie Kieffer, Clémence Lalande, Geraldina Poggi, Katja von Hoff, Jacques Grill, François Doz, Stefan Rutkowski, Maura Massimino, Rolf-Dieter Kortmann, Brigitta Lannering, Georges Dellatolas and Mathilde Chevignard
Type: Article | 2017

D-methionine interferes with non-typeable Haemophilus influenzae peptidoglycan synthesis during growth and biofilm formation - Harriet Dawe, Evelin Berger, Carina Sihlbom, Elizabeth M. Angus, Robert P. Howlin, Jay R. Laver, Marc Tebruegge, Luanne Hall-Stoodley, Paul Stoodley, Saul N. Faust and Raymond N. Allan
Type: Article | 2017

Investigating Bordetella pertussis colonisation and immunity: protocol for an inpatient controlled human infection model - Hans De Graaf, Diane F. Gbesemete, Andrew R. Gorringe, Dimitri A. Diavatopoulos, Kent E. Kester, Saul N. Faust and Robert C. Read
Type: Article | 2017

Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study - Hans De Graaf, Priya, Subhash Sukhtankar, Barbara Arch, Nusreen Ahmad, Amanda Lees, Abigail Bennett, Catherine Spowart, Helen Hickey, Annmarie Jeanes, Kate Armon, Andrew Riordan, Jethro A. Herberg, Scott Hackett, Carrol Gamble, Delane Shingadia, Ann Pallett, Stuart C. Clarke, Philip Henman, Marieke Emonts, Mike Sharland, Adam Finn, Andrew J. Pollard, Colin Powell, Peter Marsh, Claire Ballinger, Paula R. Williamson, Nicholas MP Clarke and Saul Faust
Type: Article | 2017

Type: Article | 2017

The rise and fall of pneumococcal serotypes carried in the PCV era - Vanessa T. Devine, David W. Cleary, Johanna M.C. Jefferies, Rebecca Anderson, Denise E. Morris, Andrew C. Tuck, Rebecca A. Gladstone, Grace O'Doherty, Priyasharmila Kuruparan, Stephen D. Bentley, Saul N. Faust and Stuart C. Clarke
Type: Article | 2017

Arterial pulsations cannot drive intramural periarterial drainage: significance for Aβ drainage - Alexandra Diem, Matthew Macgregor Sharp, Maureen Gatherer, Neil Bressloff, Roxana-Octavia Carare and Giles Richardson
Type: Article | 2017

Nocturnal oxyhemoglobin desaturation and arteriopathy in a pediatric sickle cell disease cohort - Nomazulu Dlamini, Dawn E Saunders, Michael Bynevelt, Sara Trompeter, Timothy C Cox, Romola S Bucks and Fenella J Kirkham
Type: Article | 2017

The perivascular pathways for influx of cerebrospinal fluid are most efficient in the midbrain - Howard Dobson, Matthew MacGregor Sharp, Richard Cumpsty, Theodore P. Criswell, Tyler Wellman, Ciara Finucane, Jenna M Sullivan, Roy O. Weller, Ajay Verma and Roxana O. Carare
Type: Article | 2017 | Item not available on this server.

Altered neurophysiological processing of auditory attention in preschool children with sickle cell disease - Michelle Downes, Fenella J. Kirkham, Paul T Telfer and Michelle de Haan
Type: Article | 2017 | Item availability restricted.

Hot topics in reactive oxygen therapy: antimicrobial and immunological mechanisms, safety, and clinical applications - Matthew Dryden, Jonathan Cooke, Rami Salib, Rebecca Holding, Sylvia Pender and Jill Brooks
Type: Article | 2017

Hearing the suicidal patient’s emotional pain: a typological model to improve communication - Christine Dunkley, Alan Borthwick, Ruth Bartlett, Laura Dunkley, Steven Palmer, Stefan Gleeson and David Kingdon
Type: Article | 2017

Development and Preliminary Validation of the Food Intolerance Quality of Life Questionnaire (FIQLQ): Adult form - Audrey DunnGalvin, Julie Barnett, Fiona M. Began, Kathleen Ryan and Jane S. Lucas
Type: Article | 2017

Ammonium tetrathiomolybdate following ischemia/reperfusion injury: chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models - Alex Dyson, Felipe Dal-Pizzol, Giovanni Sabbatini, Anna B. Lach, Federica Galfo, Juliano Dos Santos Cardoso, Bruna Pescador Mendonça, Iain Hargreaves, Bernardo Bollen Pinto, Daniel I. Bromage, John F. Martin, Kevin P. Moore, Martin Feelisch and Mervyn Singer
Type: Article | 2017

Corticosteroids and infliximab impair the performance of interferon-γ release assays used for diagnosis of latent tuberculosis - Alexander Edwards, Yifang Gao, Raymond Allan, Darran Ball, Hans De Graaf, Tracy Coelho, Vanessa Clifford, Nigel Curtis, Tony Williams, Saul Faust, Salah Mansour, Ben Marshall, Paul Elkington and Marc Tebruegge
Type: Article | 2017

Type: Article | 2017

Maternal stress and psychological distress preconception:: association with offspring atopic eczema at age 12 months - S. El-Heis, S. R. Crozier, E. Healy, S. M. Robinson, N. C. Harvey, C. Cooper, H. M. Inskip, J. Baird and K. M. Godfrey
Type: Article | 2017

The role of DNA methylation in type 2 diabetes aetiology – using genotype as a causal anchor - Hannah Elliot, Hashem Shihab, Gabrielle A. Lockett, John Holloway, Allan F. McRae, George Davey-Smith, Susan M. Ring, Tom R. Gaunt and Caroline L. Relton
Type: Article | 2017

Real-time measurement of the intracellular pH of yeast cells during glucose metabolism using ratiometric fluorescent nanosensors - Mohamed M. Elsutohy, Veeren M. Chauhan, Robert Markus, Mohammed Aref Kyyaly, Saul J.B. Tendler and Jonathan W. Aylott
Type: Article | 2017 | Item not available on this server.

STAT4 expression and activation is increased during mitosis in vitro and in vivo in skin and mucosa derived cell type: implications in neoplastic and inflammatory skin diseases - C. Ferreli, C. Lai, S. August, Y. Buggy, P. Kumar, N. Brownlow, P. Parker, P.S. Friedmann, M. Ardern-Jones, C. Pickard and E. Healy
Type: Article | 2017

Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice - Naomi Fleury, Martin Feelisch, Prue H Hart, Richard B Weller, Jordan Smoothy, Vance B Matthews and Shelley Gorman
Type: Article | 2017 | Item not available on this server.

Fundus autofluorescence imaging: systematic review of test accuracy for the diagnosis and monitoring of retinal conditions - Geoff K. Frampton, Neelam Kalita, Elizabeth Payne, Jillian Colquitt, Emma Loveman, Susan M. Downes and Andrew Lotery
Type: Article | 2017

Innate immunity in Alzheimer's disease: the relevance of animal models? - Diana K. Franco Bocanegra, James A.R. Nicoll and Delphine Boche
Type: Article | 2017

In vitro human T cell responses to diphencyprone - Peter Friedmann, Ciara Haddadeen, Chester Lai and Eugene Healy
Type: Article | 2017

Haptoglobin genotype and outcome after subarachnoid haemorrhage: new insights from a meta-analysis - Benjamin Gaastra, James Glazier, Diederik Bulters and Ian Galea
Type: Article | 2017

Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer - Anusha-Preethi Ganesan, James Clarke, Oliver Wood, Eva M Garrido-Martin, Serena J. Chee, Toby Mellows, Daniela Samaniego-Castruita, Divya Singh, Grégory Seumois, Aiman Alzetani, Edwin Woo, Peter S Friedmann, Emma V King, Gareth J Thomas, Tilman Sanchez-Elsner, Pandurangan Vijayanand and Christian H Ottensmeier
Type: Article | 2017

CD48 on blood leukocytes and in serum of asthma patients varies with severity - Roopesh S. Gangwar, Y. Minai-Fleminger, M. Seaf, A. Gutcold, A. Shikotra, C. Barber, A. Chauhan, S. Holgate, P. Bradding, P. Howarth, R. Elishar, N. Berkman and F. Levi_Schaffer
Type: Article | 2017 | Item not available on this server.

Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA2LEN) Survey - Vanessa Garcia-larsen, Rhonda Arthur, James F. Potts, Peter H. Howarth, Matti Ahlström, Tari Haahtela, Carlos Loureiro, Ana Todo Bom, Grzegorz Brożek, Joanna Makowska, Marek L. Kowalski, Trine Thilsing, Thomas Keil, Paolo M. Matricardi, Kjell Torén, Thibaut Van Zele, Claus Bachert, Barbara Rymarczyk, Christer Janson, Bertil Forsberg, Ewa Niżankowska-mogilnicka and Peter G. J. Burney
Type: Article | 2017

Current research priorities in perioperative intensive care medicine - Michael A. Gillies, Michael Sanders, Andrew Shaw, Duminda N. Wijeysundera, John Myburgh, Cesar Aldecoa, Ib Jammer, Suzana M. Lobo, Naomi Pritchard, Michael P.W. Grocott, Marcus J. Schultz and Rupert M. Pearse
Type: Article | 2017

Pre-vaccine serotype composition within a lineage signposts its serotype replacement - a carriage study over 7 years following pneumococcal conjugate vaccine use in the UK - Rebecca A. Gladstone, Vanessa Devine, Jessica Jones, David Cleary, Johanna M. Jefferies, Stephen D. Bentley, Saul N. Faust and Stuart C. Clarke
Type: Article | 2017

Growth and nutritional status, and their association with lung function: a study from the International Primary Ciliary Dyskinesia Cohort - Myrofora Goutaki, Florian S. Halbeisen, Ben D. Spycher, Elisabeth Maurer, Fabien Belle, Israel Amirav, Laura Behan, Mieke Boon, Siobhan Carr, Carmen Casaulta, Annick Clement, Suzanne Crowley, Sharon Dell, Thomas Ferkol, Eric G. Haarman, Bulent Karadag, Michael Knowles, Cordula Koerner-Rettberg, Margaret W. Leigh, Michael R. Loebinger, Henryk Mazurek, Lucy Morgan, Kim G. Nielsen, Maria Phillipsen, Scott D. Sagel, Francesca Santamaria, Nicolaus Schwerk, Panayiotis Yiallouros, Jane S. Lucas and Claudia E. Kuehni
Type: Article | 2017

The international primary ciliary dyskinesia cohort (iPCD Cohort): methods and first results - Myrofora Goutaki, Elisabeth Maurer, Florian S. Halbeisen, Israel Amirav, Angelo Barbato, Laura Behan, Mieke Boon, Carmen Casaulta, Annick Clement, Suzanne Crowley, Eric Haarman, Claire Hogg, Bulent Karadag, Cordula Koerner-Rettberg, Margaret W. Leigh, Michael R. Loebinger, Henryk Mazurek, Lucy Morgan, Kim G. Neilsen, Heymut Omran, Nicolaus Schwerk, Sergio Scigliano, Claudius Werner, Panayiotis Yiallouros, Zorica Zivkovic, Jane S. Lucas and Claudia E. Kuehni
Type: Article | 2017

Anatomical subgroup analysis of the MERIDIAN cohort:: Ventriculomegaly - P. D. Griffiths, K. Brackley, M. Bradburn, D. J. A. Connolly, M. L. Gawne-Cain, D. I. Griffiths, M. D. Kilby, L. Mandefield, C. Mooney, S. C. Robson, B. Vollmer and G. Mason
Type: Article | 2017

Anatomical subgroup analysis of the MERIDIAN cohort: failed commissuration - Paul D. Griffiths, Karen Brackley, Michael Bradburn, Daniel J.A. Connolly, Mary L. Gawne-Cain, Daniel I. Griffiths, Mark D. Kilby, Laura Mandefield, Cara Mooney, Stephen C. Robson, Brigitte Vollmer and Gerald Mason
Type: Article | 2017

Anatomical subgroup analysis of the MERIDIAN cohort: Posterior fossa abnormalities - Paul D. Griffiths, Karen Brackley, Michael Bradburn, Daniel J.A. Connolly, Mary L. Gawne-Cain, Mark D. Kilby, Laura Mandefield, Cara Mooney, Stephen C. Robson, Brigitte Vollmer and Gerald Mason
Type: Article | 2017

Caudwell Xtreme Everest: A prospective study of the effects of environmental hypoxia on cognitive functioning - Konstadina Griva, Jan Stygall, Mark H. Wilson, Daniel Martin, Denny Levett, Kay Mitchell, Monty Mythen, Hugh E. Montgomery, Mike P. Grocott, Golnar Aref-Adib, Mark Edsell, Tracie Plant, Chris Imray, Debbie Cooke, Jane Harrington, Maryam Khosravi and Stanton P. Newman
Type: Article | 2017

The acceptability and tolerability of nasal douching in children with allergic rhinitis: A systematic review - Nelson Gutierrez-Cardona, Paula Sands, Graham Roberts, Jane S. Lucas, Woolf Walker, Rami Salib, Andrea Burgess and Hasnaa Ismail-Koch
Type: Article | 2017 | Item availability restricted.

Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion - James Hadfield, Simon R. Harris, Helena M.B. Seth-Smith, Surendra Parmar, Patiyan Andersson, Philip M. Giffard, Julius Schachter, Jeanne Moncada, Louise Ellison, María Lucía Gallo Vaulet, Marcelo Rodríguez Fermepin, Frans Radebe, Suyapa Mendoza, Sander Ouburg, Servaas A. Morré, Konrad Sachse, Mirja Puolakkainen, Suvi J. Korhonen, Chris Sonnex, Rebecca Wiggins, Hamid Jalal, Tamara Brunelli, Patrizia Casprini, Rachel Pitt, Cathy Ison, Alevtina Savicheva, Elena Shipitsyna, Ronza Hadad, Laszlo Kari, Matthew J. Burton, David Mabey, Anthony W. Solomon, David Lewis, Peter Marsh, Magnus Unemo, Ian N. Clarke, Julian Parkhill and Nicholas R. Thomson
Type: Article | 2017

An induced pluripotent stem cell patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure - Dean Hallam, Joseph F. Collin, Sanja Bojic, Valeria Chichagova, Adriana Buskin, Georgios Anyfantis, Lyle Armstrong, Stefan Przyborski, Viktor I Korolchuk, Andrew Lotery, Gabriele Saretzki, Martin McKibbin, D. Steel, Valeria Chichagova, Yaobo Xu, Lucia Lafage, Carla Mellough, Sameer Alharthi, D. Kavanagh and Majlinda Lako
Type: Article | 2017

Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

A role for the tetraspanin proteins in Salmonella infection of human macrophages - Noha A. Hassuna, Peter N. Monk, Fawwaz Ali, Robert C. Read and Lynda J. Partridge
Type: Article | 2017 | Item not available on this server.

Global funding trends for malaria research in sub-Saharan Africa: a systematic analysis - Michael Head, Sian Goss, Yann Gelister, Victor Alegana, Rebecca Brown, Stuart Clarke, Joseph R.A. Fitchett, Rifat Atun, J. Anthony G. Scott, Marie-Louise Newell, Sabu Padmadas and Andrew Tatem
Type: Article | 2017

Type: Article | 2017

Type: Article | 2017

Group B Streptococcus and Respiratory Syncytial Virus immunization during pregnancy: a landscape analysis - Paul Heath, Fiona J. Culley, Christine E. Jones, Beate Kampmann, Kirsty Le Doare, Marta Nunes, Manish Sadarangani, Zain Chaudhry, Carol J. Baker and Peter J.M. Openshaw
Type: Article | 2017

Enhancing the biological relevance of machine learning classifiers for reverse vaccinology - Ashley Heinson, Yawwani P Gunawardana, Bastiaan Moesker, Carmen C. Denman Hume, Elena Vataga, Yper Hall, Elena Stylianou, Helen Mcshane, Ann Williams, Mahesan Niranjan and Christopher H. Woelk
Type: Article | 2017

Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma - P.P. Hekking, M.J. Loza, S. Pavlidis, B. De Meulder, D. Lefaudeux, F. Baribaud, C. Auffray, A.H. Wagener, P. Brinkman, R. Lutter, A.T. Bansal, A.R. Sousa, S. Bates, Y. Pandis, L.J. Fleming, D.E. Shaw, S.J. Fowler, Y. Guo, A. Meiser, K. Sun, J. Corfield, P. Howarth, E.H. Bel, I.M. Adcock, K.F. Chung, R. Djukanovic and P.J. Sterk
Type: Article | 2017

Pathway discovery using transcriptomic profiles in adult-onset severe asthma - Pieter-Paul Hekking, Matt J. Loza, Stelios Pavlidis, Bertrand De Meulder, Diane Lefaudeux, Fred Baribaud, Charles Auffray, Ariane H. Wagener, Paul Brinkman, Rene Lutter, Aruna T. Bansal, Ana R. Sousa, Steve Bates, Yannis Pandis, Louise J. Fleming, Dominique E. Shaw, Stephen J. Fowler, Y. Guo, Andrea Meiser, Kai Sun, Julie Corfield, Peter Howarth, Elisabeth H. Bel, Ian M. Adcock, K.F. Chung, Ratko Djukanovic and Peter J. Sterk
Type: Article | 2017

Vascular basement membrane alterations and β-amyloid accumulations in an animal model of cerebral small vessel disease - Friederike Held, Alan W.J. Morris, Daniel Pirici, Solveig Niklass, Matthew M.G. Sharp, Cornelia Garz, Anne Assmann, Hans-Jochen Heinze, Frank Schreiber, Roxana Octavia Carare and Stefanie Schreiber
Type: Article | 2017 | Item not available on this server.

Hearing loss mediates executive function impairment in sleep disordered breathing - Catherine Hill, Romola S. Bucks, Colin Kennedy, Dawn Harrison, Annette Carroll, Nicolas Upton and Alexandra Hogan
Type: Article | 2017

Metabolic basis to Sherpa altitude adaptation - James A. Horscroft, Aleksandra O. Kotwica, Verena Laner, James A. West, Philip J. Hennis, Denny Z.H. Levett, David J. Howard, Bernadette O. Fernandez, Sarah L. Burgess, Zsuzsanna Ament, Edward T. Gilbert-Kawai, Andre Vercueil, Blaine D. Landis, Kay Mitchell, Monty G. Mythen, Cristina Branco, Randall S. Johnson, Martin Feelisch, Hugh E. Montgomery, Julian L. Griffin, Michael P.W. Grocott, Erich Gnaiger, Daniel S. Martin and Andrew J. Murray
Type: Article | 2017

Type: Article | 2017 | Item availability restricted.

Peripheral inflammatory cytokines and immune balance in Generalised Anxiety Disorder: case-controlled study - Ruihua Hou, Matthew Garner, Clive Holmes, Clive Osmond, Jessica Teeling, Laurie Lau and David S. Baldwin
Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

Type: Article | 2017

Type: Article | 2017

Low-dose nitric oxide as targeted anti-biofilm adjunctive therapy to treat chronic Pseudomonas aeruginosa infection in cystic fibrosis - Robert P. Howlin, Katrina Cathie, Luanne Hall-Stoodley, Victoria Cornelius, Caroline Duignan, Raymond N. Allan, Bernadette O. Fernandez, Nicolas Barraud, Ken D. Bruce, Johanna Jefferies, Michael Kelso, Staffan Kjelleberg, Scott A. Rice, Geraint B. Rogers, Sandra Pink, Caroline Smith, Priya S. Sukhtankar, Rami Salib, Julian Legg, Mary Carroll, Thomas Daniels, Martin Feelisch, Paul Stoodley, Stuart C. Clarke, Gary Connett, Saul N. Faust and Jeremy S. Webb
Type: Article | 2017

Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor. - Maria Humbert, Amaka Awanye, Li Lian, Jeremy Derrick and Myron Christodoulides
Type: Article | 2017

Hepatic steatosis accompanies pulmonary alveolar proteinosis - Alan Hunt, Anagha Malur, Tual, Remy Monfort, Pavlos Lagoudakis, Sumeet Mahajan, Anthony Postle and Mary Jane Thomassen
Type: Article | 2017

Human lung fibroblasts present bacterial antigen to autologous lung T helper cells - Andrew J. Hutton, Marta E. Polak, C. Mirella Spalluto, Joshua C. Wallington, Christopher Pickard, Karl J. Staples, Jane A. Warner and Tom M.A. Wilkinson
Type: Article | 2017 | Item availability restricted.

PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations - Agnieszka A Janeczek, Edoardo Scarpa, Mathew H. Horrocks, Rahul S. Tare, Caroline A. Rowland, Dominic Jenner, Tracey A. Newman, Richard O.C. Oreffo, Steven F. Lee and Nicholas D. Evans
Type: Article | 2017

Antacid therapy in idiopathic pulmonary fibrosis - Kerri A. Johannson, Irina Strâmbu, Claudia Ravaglia, Jan C. Grutters, Claudia Valenzuela, Nesrin Mogulkoc, Fabrizio Luppi, Luca Richeldi, Athol U. Wells, Carlo Vancheri and Michael Kreuter
Type: Article | 2017 | Item not available on this server.

Successfully implementing and embedding guidelines to improve the nutrition and growth of preterm infants in neonatal intensive care: a prospective interventional study - Mark J. Johnson, Alison A. Leaf, Pearson Freya, Howard W. Clark, Borislav D. Dimitrov, Catherine Pope and Carl R. May
Type: Article | 2017

Vaccination in pregnancy - Recent developments - Christine E. Jones, Anna Calvert and Kirsty Le Doare
Type: Article | 2017

Animal models of cerebral amyloid angiopathy - Lieke Jäkel, William E. Van Nostrand, James A.R. Nicoll, David J. Werring and Marcel M. Verbeek
Type: Article | 2017

Low plasma homoarginine concentration is associated with high rates of all-cause mortality in renal transplant recipients - Arslan Arinc Kayacelebi, Isidor Minović, Erik Hanff, Anne-Roos S. Frenay, Martin H. de Borst, Martin Feelisch, Harry van Goor, Stephan J.L. Bakker and Dimitrios Tsikas
Type: Article | 2017 | Item not available on this server.

Congenital cytomegalovirus infection: management update - Asma Khalil, Christine E. Jones and Yves Ville
Type: Article | 2017

Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort - Viktoriya, Leonidovna Kim, NGAIRE A COOMBS, Karl J Staples, Kristoffer Ostridge, Nicholas, Paul Williams, Stephen A Wootton, Jeanne-Marie Devaster, Emmanuel Aris, Stuart C Clarke, Andrew C Tuck, Simon Charles Bourne and Tom MA Wilkinson
Type: Article | 2017

Type: Article | 2017 | Item availability restricted.

Immunization in pregnancy clinical research in low- and middle- income countries - study design, regulatory and safety considerations - Sonali Kochhar, Jan Bonhoeffer, Christine E. Jones, Flor Munoz, Angel Honrado, Jorgen Bauwens, Ajoke Sobanjo-ter Meulen and Steven Hirschfeld
Type: Article | 2017

Nintedanib in patients with idiopathic pulmonary fibrosis and preserved lung volume - Martin Kolb, Luca Richeldi, Jürgen Behr, Toby M. Maher, Wenbo Tang, Susanne Stowasser, Christoph Hallmann and Roland M. Du Bois
Type: Article | 2017

Targeting biofilms: Current and prospective therapeutics - Hyun Koo, Raymond Allan, Robert Howlin, Paul Stoodley and Luanne Hall-Stoodley
Type: Article | 2017

Type: Article | 2017

A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED - Chih-Hsi Kuo, Stelios Pavlidis, Matthew Loza, Fred Baribaud, Anthony Rowe, Ioannis Pandis, Uruj Hoda, Christos Rossios, Ana Sousa, Susan J. Wilson, Peter Howarth, Barbro Dahlen, Sven-Erik Dahlen, Pascal Chanez, Dominick Shaw, Norbert Krug, Thomas Sandstrom, Bertrand De Meulder, Diane Lefaudeux, Stephen Fowler, Louise Fleming, Julie Corfield, Charles Auffray, Peter Sterk, Ratko Djukanovic, Yike Guo, Ian Adcock and Kian Chung
Type: Article | 2017

T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED. - Chih-Hsi Kuo, Stelios Pavlidis, Matthew Loza, Fred Baribaud, Anthony Rowe, Ioannis Pandis, Ana Sousa, Julie Corfield, Ratko Djukanovic, Rene Lutter, Peter J. Sterk, Charles Auffrey, Yike Guo, Ian M. Adcock and Kian Fan Chung
Type: Article | 2017 | Item availability restricted.

Type: Article | 2017

Type: Article | 2017 | Item availability restricted.

Comparison of miRNA profiling during airway epithelial repair in undifferentiated and differentiated cells in vitro - Wojciech Langwinski, Beata Narozna, Peter M. Lackie, John W. Holloway and Aleksandra Szczepankiewicz
Type: Article | 2017

Non-coding NOTCH1 mutations in chronic lymphocytic leukemia; their clinical impact in the UK CLL4 trial - M. Larrayoz, M.J.J. Rose-Zerilli, L. Kadalayil, H. Parker, S. Blakemore, J. Forster, Z. Davis, A.J. Steele, A. Collins, M. Else, D. Catovsky, D.G. Oscier and J.C. Strefford
Type: Article | 2017

Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-β1 - Ee Soo Lee, Llorenç Solé Boldo, Bernadette O Fernandez, Martin Feelisch and Martin C Harmsen
Type: Article | 2017 | Item not available on this server.

Positioning children’s voice in clinical trials research: A new model for planning, collaboration, and reflection - Amanda Lees, Jane K. Payler, Claire Ballinger, Penny Lawrence, Saul N. Faust and Geoffrey Meads
Type: Article | 2017

Prevalence of age‐related macular degeneration in Europe: the past and the future - Andrew Lotery, Johanna Colijn, Gabriëlle H.S. Buitendijk, Elena Prokofyeva, Dalila Alves, Maria Cachulo, Anthony Khawaja, Audrey Cougnard-Gregoire, Benedicte Merle, Christina Korb, Maja Erke, A Bron, Eleftherios Anastasopoulos, Magda Meester-Smoor, Tatiana Segato, Stefano Piermarocchi, P. De Jong, J.R. Vingerling, Fotis Topouzis, Catherine Creuzot-Garcher, Geir Bertelsen, Norbert Pfeiffer, A Fletcher, Paul J. Foster, Rufino Silva, Jean-François Korobelnik, Cécile Delcourt and Caroline C.W. Klaver
Type: Article | 2017

Type: Article | 2017

Type: Article | 2017

Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of Rhinovirus - Matthew Loxham, David Smart, Nicole Bedke, Natalie Smithers, Irene Filippi, Cornelia Blume, Emily Swindle, Kamran Tariq, Peter Howarth, Stephen Holgate and Donna Davies
Type: Article | 2017

Type: Article | 2017

European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia - Jane Lucas, Angelo Barbato, Samuel A. Collins, Myrofora Goutaki, Laura Behan, Daan Caudri, Sharon Dell, Ernst Eber, Estelle Escudier, Robert A. Hurst, Claire Hogg, Mark Jorissen, Philipp Latzin, Marie Legendre, Margaret W. Leigh, Fabio Midulla, Kim G. Nielsen, Heymut Omran, Jean-Francois Papon, Petr Pohunek, Beatrice Redfern, David Rigau, Bernhard Rindlisbacher, Francesca Santamaria, Amelia Shoemark, Deborah Snijders, Thomy Tonia, Andrea Titieni, Woolf T. Walker, Claudius Werner, Andrew Bush and Claudia E. Kuehni
Type: Article | 2017

Exploring the art of ciliary beating: the benefits of high-speed video analysis - Jane Lucas, HJ Evans, EG Haarman, RA Hirst, C Hogg, Claire Jackson, KG Nielsen, H Omran, J-F Papon, P Robinson, A Shoemark and WT Walker
Type: Article | 2017

Clinical care of children with primary ciliary dyskinesia - Jane S. Lucas, MIkkel Christian Alanin, Samuel Collins, Amanda Harris, Helle Krogh Johansen, Kim G. Nielsen, Jean-Francois Papon, Phil Robinson and Woolf T. Walker
Type: Article | 2017

Diagnostic methods in primary ciliary dyskinesia: Mini-symposium: Primary Ciliary Dyskinesia - Jane S. Lucas, Tamara Paff, Patricia Goggin and Eric Haarman
Type: Article | 2017

Changes in acute pulmonary vascular responsiveness to hypoxia during a progressive ascent to high altitude (5,300 m) - Andrew M. Luks, Denny Levett, Daniel S. Martin, Christopher Goss, Kay Mitchell, Bernadette O. Fernandez, Martin Feelisch, Michael P. Grocott and Erik R. Swenson
Type: Article | 2017 | Item not available on this server.

The complexities underlying age-related macular degeneration- could Amyloid beta play an important role? - Savannah Lynn, Eloise Keeling, Rosie Munday, Gagandeep Gabha, Helen Griffiths, Andrew Lotery and J. Arjuna Ratnayaka
Type: Article | 2017

Maternal immunization: collaborating with Mother Nature - Arnaud Marchant, Manish Sadarangani, Mathieu Garand, Nicolas Dauby, Valerie Verhasselt, Lenore Pereira, Gordean Bjornson, Christine E. Jones, Scott Halperin, Kathryn M. Edwards, Paul Heath, Peter Openshaw, David W. Scheifele and Tobias R. Kollman
Type: Article | 2017

Pseudotumor cerebri syndrome in childhood: incidence, clinical profile and risk factors in a national prospective population-based cohort study - Yim-Yee Matthews, Fiona Dean, Ming J. Lim, Karen Mclachlan, Alan S. Rigby, Guirish A. Solanki, Catharine P. White, William P. Whitehouse and Colin R. Kennedy
Type: Article | 2017

British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017 - R. Hamish McAllister-Williams, David S. Baldwin, Roch Cantwell, Abby Easter, Eilish Gilvarry, Vivette Glover, Lucian Green, Alain Gregoire, Louise M. Howard, Ian Jones, Hind Khalifeh, Anne Lingford-Hughes, Elizabeth McDonald, Nadia Micali, Carmine M. Pariante, Lesley Peters, Ann Roberts, Natalie C. Smith, David Taylor, Angelika Wieck, Laura M. Yates and Allan H. Young
Type: Article | 2017

Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial - Daniel F. McAuley, L. J. Mark Cross, Umar Hamid, Evie Gardner, J. Stuart Elborn, Kathy M. Cullen, Ahilanandan Dushianthan, Michael P. W. Grocott, Michael A. Matthay and Cecilia M. O'Kane
Type: Article | 2017 | Item not available on this server.

Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis - Massimiliano Mellone, Christopher Hanley, Stephen Thirdborough, Toby Mellows, Edwin Garcia, Jeongmin Woo, Joanne Tod, Steven Frampton, Veronika Jenei, Karwan Moutasim, Tasnuva D. Kabir, Peter A Brennan, Giulia Venturi, Kirsty Ford, Nicolas Herranz, Kue Peng Lim, James Clarke, Daniel W. Lambert, Stephen S. Prime, Timothy J. Underwood, Pandurangan Vijayanand, Kevin W. Eliceiri, Christopher Woelk, Emma King, Jesus Gil, Christian Ottensmeier and Gareth Thomas
Type: Article | 2017

Epigenetic regulation of matrix metalloproteinase-1 and -3 expression in mycobacterium tuberculosis Infection - Rachel Moores, Sara Brilha, Frans Schutgens, Paul Elkington and Jon Friedland
Type: Article | 2017

The Beliefs about Paranoia Scale: confirmatory factor analysis and tests of a metacognitive model of paranoia in a clinical sample - Elizabeth K. Murphy, Sarah Tully, Melissa Pyle, Andrew I. Gumley, David Kingdon, Matthias Schwannauer, Douglas Turkington and Anthony P Morrison
Type: Article | 2017

Increased expression of p22phox mediates airway hyperresponsiveness in an experimental model of asthma - Chandran Nagaraj, Hans Michael Haitchi, Akos Heinemann, Peter Howarth, Andrea Olschewski and Leigh M Marsh
Type: Article | 2017

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C - Mohammed M. Naiyer, Sorcha A. Cassidy, Andrea Magri, Vanessa Cowton, Kevin Chen, Salah Mansour, Hariklia Kranidioti, Berenice Mbiribindi, Pauline Rettman, Scott Harris, Liam J. Fanning, Arend Mulder, Franz H.J. Claas, Andrew D. Davidson, Arvind H. Patel, Marco A. Purbhoo and Salim I. Khakoo
Type: Article | 2017

MicroRNA-328 is involved in wound repair process in human bronchial epithelial cells - Beata Narożna, Wojciech Langwinski, Claire Jackson, Peter Lackie, John W. Holloway and Aleksandra Szczepankiewicz
Type: Article | 2017

Fetal hemoglobin is associated with peripheral oxygen saturation in sickle cell disease in Tanzania - Siana Nkya, Josephine Mgaya, Florence Urio, Abel Makubi, Swee Lay Thein, Stephan Menzel, Sharon E Cox, Charles R Newton, Fenella J Kirkham, Bruno P Mmbando and Julie Makani
Type: Article | 2017

Identification of a functionally significant tri-allelic genotype in the Tyrosinase gene (TYR) causing hypomorphic oculocutaneous albinism (OCA1B) - Chelsea S. Norman, Luke O'Gorman, Jane Gibson, Reuben J. Pengelly, Diana Baralle, J. Arjuna Ratnayaka, Helen Griffiths, Matthew Rose-Zerilli, Megan Ranger, David Bunyan, Helena Lee, Rhiannon Page, Tutte Newall, Fatima Shawkat, Christopher Mattocks, Daniel Ward, Sarah Ennis and Jay E. Self
Type: Article | 2017

Clinical practice with anti-dementia drugs: a revised (third) consensus statement from the British Association for Psychopharmacology - John O'Brien, Clive Holmes, Matthew Jones, Roy Jones, Gill Livingstone, Ian McKeith, Peter Mittler, Peter Passmore, Craig Ritchie, Louise Robinson, Elizabeth Sampson, John-Paul Taylor, Alan Thomas and Alistair Burns
Type: Article | 2017

Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial - Finbar J.K. O'Callaghan, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew A. Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity and John P. Osborne
Type: Article | 2017

Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis - Catherine W.M. Ong, Przemyslaw J. Pabisiak, Sara Brilha, Poonam Singh, Frederico Roncaroli, Paul T. Elkington and Jon S. Friedland
Type: Article | 2017

Human second window pre-conditioning and post-conditioning by nitrite is influenced by a common polymorphism in mitochondrial aldehyde dehydrogenase - Julian O.M. Ormerod, Jonathan D.W. Evans, Hussain Contractor, Matteo Beretta, Sayqa Arif, Bernadette O. Fernandez, Martin Feelisch, Bernd Mayer, Rajesh K. Kharbanda, Michael P. Frenneaux and Houman Ashrafian
Type: Article | 2017

Neisseria lactamica Y92-1009 complete genome sequence - Anish K. Pandey, David W. Cleary, Jay R. Laver, Martin C.J. Maiden, Xavier Didelot, Andrew Gorringe and Robert C. Read
Type: Article | 2017

Effect of anti-cancer drugs on microglia in patient-derived breast cancer xenografted mouse models - Claire Paquet, Delphine Boche, Morad El Bouchtaoui, Sarah Gourmaud, Anne Janin and Guilhem Bousquet
Type: Article | 2017

Downregulated apoptosis and autophagy after anti-Aβ immunotherapy in Alzheimer’s disease - Claire Paquet, James Nicoll, Seth Love, François Mouton-Liger, Clive Holmes, Jacques Hugon and Delphine Boche
Type: Article | 2017

Aflibercept treatment for neovascular AMD beyond the first year: consensus recommendations by a UK expert roundtable panel, 2017 update - Praveen J. Patel, Helen Devonport, Sobha Sivaprasad, Adam H. Ross, Gavin Walters, Richard P. Gale, Andrew J. Lotery, Sajjad Mahmood, James S. Talks and Jackie Napier
Type: Article | 2017

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions - Ruth O. Payne, Sarah Silk, Sean Elias, Kazutoyo Miura, Ababacar Diouf, Francis Galaway, Hans De Graaf, Nathan Brendish, Ian D. Poulton, Oliver J. Griffiths, Nick J. Edwards, Jing Jin, Genevieve M. Labbe, Daniel G.W. Alanine, Loredana Siani, Stefania Di Marco, Rachel Roberts, Nicky Green, Eleanor Berrie, Andrew Ishizuka, Carolyn M. Nielsen, Martino Bardelli, Frederica D. Partey, Michael F. Ofori, Lea Barfod, Juliana Wambua, Linda M. Murungi, Faith H. Osier, Sumi Biswas, James S. McCarthy, Angela M. Minassian, Rebecca Ashfield, Nicola K. Viebig, Fay L. Nugent, Alexander D. Douglas, Johan Vekemans, Gavin J. Wright, Saul N. Faust, Adrian V.S. Hill, Carole A. Long, Alison M. Lawrie and Simon J. Draper
Type: Article | 2017

Locked Nucleic Acid gapmers and conjugates induce potent silencing of ADAM33, an asthma-associated metalloprotease with nuclear-localized mRNA - Hannah M Pendergraff, Pranathi Meda Krishnamurthy, Alexandre J. Debacker, Michael Moazami, Vivek K. Sharma, Liisa Niitsoo, Yong Yu, Yen Nee Tan, Hans Michael Haitchi and Jonathan K. Watts
Type: Article | 2017

Language outcomes in deaf or hard of hearing teenagers who are spoken language users: effects of universal newborn hearing screening and early confirmation - Hannah Pimperton, Jana Kreppner, Merle Mahon, James Stevenson, Emmanouela Terlektsi, Sarah Worsfold, Ho Yuen and Colin Kennedy
Type: Article | 2017

Petri Net computational modelling of Langerhans cell Interferon Regulatory Factor Network predicts their role in T cell activation - Marta Polak, Chuin Ying Ung, Joanna Masapust, Tom C. Freeman and Michael Ardern-Jones
Type: Article | 2017

Airway and peripheral uPAR is elevated in asthma, and identifies a severe, non-atopic subset of patients - Michael A. Portelli, Christopher Moseley, Ceri E. Stewart, Dirkje S. Postma, Peter Howarth, Jane A. Warner, John W. Holloway, Gerard H. Koppelman, Chris Brightling and Ian Sayers
Type: Article | 2017

Autoimmunity/inflammation in a monogenic primary immunodeficiency cohort - William Rae, Daniel Ward, Christopher Mattocks, Yifang Gao, Reuben J. Pengelly, Sanjay V. Patel, Sarah Ennis, Saul Faust and Anthony P. Williams
Type: Article | 2017

Clinical efficacy of a next-generation sequencing gene panel for primary immunodeficiency diagnostics - William Rae, Daniel Ward, Christopher Mattocks, Reuben J. Pengelly, Efrem Eren, Sanjay V. Patel, Saul N. Faust, David Hunt and Anthony P. Williams
Type: Article | 2017

Maternal body mass: relation with infant respiratory symptoms and infections - Ashley Rajappan, Anna Pearce, Hazel Inskip, Janis Baird, Sarah Crozier, Cyrus Cooper, Keith Godfrey, Graham Roberts, Jane Lucas and Katharine Pike
Type: Article | 2017

Type: Article | 2017

Metabolomics analysis identifies different metabotypes of asthma severity - Stacey Reinke, Hector Gallart-Ayala, Cristina Gomez, Antonio Checa, Alexander Fauland, Shama Naz, Muhammed Kamleh, Ratko Djukanovic, Timothy Hinks and Craig Wheelock
Type: Article | 2017 | Item availability restricted.

The Edinburgh Consensus: preparing for the advent of disease-modifying therapies for Alzheimer’s disease - Craig W. Ritchie, Tom C. Russ, Sube Banerjee, Bob Barber, Andrew Boaden, Nick C. Fox, Clive Holmes, Jeremy D. Isaacs, Ira Leroi, Simon Lovestone, Matt Norton, John O'Brien, Jim Pearson, Richard Perry, James Pickett, Adam D. Waldman, Wai Lup Wong, Martin Rossor and Alistair Burns
Type: Article | 2017

Type: Article | 2017

A systematic review to assess the “Treat-and-Extend” dosing regimen for neovascular age-related macular degeneration using ranibizumab - S.R. Rufai, H. Almuhtaseb, Richard Paul, B.L. Stuart, T. Kendrick, H. Lee and A.J. Lotery
Type: Article | 2017

A novel method for examining corneal endothelial cell morphology in infants - S.R. Rufai, N.Y. Tan, R. Barbara, R. Hartrey and J.E. Self
Type: Article | 2017

Diagnosis of primary ciliary dyskinesia: potential options for resource-limited countries - Nisreen Rumman, Claire Jackson, Samuel Collins, Patricia Goggin, Janice Coles and Jane Lucas
Type: Article | 2017

Bone and joint infections - Jesus Saavedra-Lozano, Oana Falup-Pecurariu, Saul N. Faust, Hermann Girschick, Nico Hartwig, Sheldon Kaplan, Mathie Lorrot, Elpis Mantadakis, Heikki Peltola, Pablo Rojo, Theoklis Zaoutis and Anton LeMair
Type: Article | 2017 | Item availability restricted.

Inorganic nitrate in angina study: A randomized double-blind placebo-controlled trial - Konstantin Schwarz, Satnam Singh, Satish Parasuraman, Amelia Rudd, Lee Shepstone, Martin Feelisch, Magdalena Minnion, Shakil Ahmad, Melanie Madhani, John Horowitz, Dana Dawson and Michael P. Frenneaux
Type: Article | 2017

Differential recognition of mycobacterium tuberculosis-specific epitopes as a function of tuberculosis disease history - Thomas J. Scriba, Chelsea Carpenter, Sebastian Carrasco Pro, John Sidney, Munyaradzi Musvosvi, Virginie Rozot, Grégory Seumois, Sandy L. Rosales, Pandurangan Vijayanand, Delia Goletti, Edward Makgotlho, Willem Hanekom, Mark Hatherill, Bjoern Peters, Alessandro Sette and Cecilia S. Lindestam Arlehamn
Type: Article | 2017 | Item not available on this server.

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium - Gemma C. Sharp, Lucas A. Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M. Everson, Jon Bohlin, Zongli Xu, Rae-Chi Huang, Sarah E. Reese, Cheng-Jian Xu, Nour Baïz, Cathrine Hoyo, Golareh Agha, Ritu Roy, John W. Holloway, Akram Ghantous, Simon K. Merid, Kelly M. Bakulski, Leanne K. Küpers, Hongmei Zhang, Rebecca C. Richmond, Christian M. Page, Liesbeth Duijts, Rolv T. Lie, Phillip E. Melton, Judith M. Vonk, Ellen A. Nohr, Clarlynda Williams-Devane, Karen Huen, Sheryl L. Rifas-Shiman, Carlos Ruiz-Arenas, Semira Gonseth, Faisal I. Rezwan, Zdenko Herceg, Sandra Ekström, Lisa Croen, Fahimeh Falahi, Patrice Perron, Margaret R. Karagas, Bilal M. Quraishi, Matthew Suderman, Maria C. Magnus, Vincent W.V. Jaddoe, Jack A. Taylor, Denise Anderson, Shanshan Zhao, Henriette A. Smit, Michele J. Josey, Asa Bradman, Andrea A. Baccarelli, Mariona Bustamante, Siri E. Håberg, Göran Pershagen, Irva Hertz-Picciotto, Craig Newschaffer, Eva Corpeleijn, Luigi Bouchard, Debbie A. Lawlor, Rachel L. Maguire, Lisa F. Barcellos, George Davey Smith, Brenda Eskenazi, Wilfried Karmaus, Carmen J. Marsit, Marie-France Hivert, Harold Snieder, M. Daniele Fallin, Erik Melén, Monica C. Munthe-Kaas, Hasan Arshad, Joseph L. Wiemels, Isabella Annesi-Maesano, Martine Vrijheid, Emily Oken, Nina Holland, Susan K. Murphy, Thorkild I.A. Sørensen, Gerard H. Koppelman, John P. Newnham, Allen J. Wilcox, Wenche Nystad, Stephanie J. London, Janine F. Felix and Caroline L. Relton
Type: Article | 2017

A high prevalence CCDC103 p.His154Pro mutation causing primary ciliary dyskinesia disrupts protein oligomerisation and is associated with normal diagnostic investigations - Amelia Shoemark, Eduardo Moya, Robert A. Hirst, M.P. Patel, Evelyn A. Robson, Jane Hayward, Juliet Scully, Mahmoud R. Fassad, William Lamb, Miriam Schmidts, Mellisa Dixon, Ramila S. Patel-King, Andrew V. Rogers, Andrew Rutman, Claire L. Jackson, Patricia Goggin, Bruna Rubbo, Sarah Ollosson, Siobhan Carr, Woolf Walker, Beryl Adler, Michael R. Loebinger, Robert Wilson, Andrew Bush, Hywel Williams, Christopher Boustred, Lucy Jenkins, Eamonn Sheridan, Eddie M.K. Chung, Christopher M. Watson, Thomas Cullup, Jane S. Lucas, Priti Kenia, Christopher O'Callaghan, Stephen M. King, Claire Hogg and Hannah M. Mitchison
Type: Article | 2017

Choroid plexus in the central canal of the spinal cord causing recurrent syringomyelia - Anan Shtaya, Ahmed-Ramadan Sadek, James A.R. Nicoll and Ali Nader-Sepahi
Type: Article | 2017

When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council - Eric L. Simpson, Marjolein Bruin-Weller, Carsten Flor, Michael Ardern-Jones, Sebastien Barbarot, Mette Deleuran, Thomas Bieber, Christian Vestergaard, Sara J. Brown, Michael J. Cork, Aaron M. Drucker, Lawrence F. Eichenfield, Regina Foelster-Holst, Emma Guttman-Yassky, Audrey Nosbaum, Nick J. Reynolds, Jonathan I. Silverberg, Jochen Schmitt, Marieke M.B. Seyger, Phyllis I. Spuls, Jean-Francois Stalder, John C. Su, Roberto Takaoka, Claudia Traidl-Hoffmann, Jacob P. Thyssen, Jorien van der Schaft, Andreas Wollenberg, Alan D. Irvine and Amy S. Paller
Type: Article | 2017

Type: Article | 2017

Metalloproteinases ADAM10 and ADAM17 mediate migration and differentiation in glioblastoma sphere-forming cells. - Elodie J. Siney, Alexander Holden, Elizabeth Casselden, Harry Bulstrode, Gareth J. Thomas and Sandrine Willaime-Morawek
Type: Article | 2017

Type: Article | 2017 | Item not available on this server.

Membrane cholesterol is essential for triterpenoid saponin augmentation of a saporin-based immunotoxin directed against CD19 on human lymphoma cells - Wendy S. Smith, Ella J. Baker, Suzanne E. Holmes, Grielof Koster, Alan N. Hunt, David A. Johnston, Sopsamorn U. Flavell and David J. Flavell
Type: Article | 2017

IFN-γ influences epithelial anti-viral responses via histone methylation of the RIG-I promoter - C. Mirella Spalluto, Akul Singhania, Doriana Cellura, Christopher H. Woelk, Tilman Sanchez-Elsner, Karl J. Staples and Thomas M.A. Wilkinson
Type: Article | 2017

Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD (vol 11, e0167250, 2016) - Karl J. Staples, Stephen Taylor, Steve Thomas, Stephanie Leung, Karen Cox, Thierry G. Pascal, Kristoffer Ostridge, Lindsay Welch, Andrew C. Tuck, Stuart C. Clarke, Andrew Gorringe and Tom M. A. Wilkinson
Type: Article | 2017 | Item not available on this server.

Emotional and behaviour difficulties in teenagers with permanent childhood hearing loss - James Stevenson, Hannah Pimperton, Jana Kreppner, Sarah Worsfold, Emmanouela Terlektsi and Colin Kennedy
Type: Article | 2017

Type: Article | 2017

A randomised controlled study of the effectiveness of breathing retraining exercises taught by a physiotherapist either by instructional DVD or in face-to-face sessions in the management of asthma in adults - M. Thomas, A. Bruton, P. Little, S. Holgate, A. Lee, L. Yardley, S. George, J. Raftery, J. Versnel, D. Price, I. Pavord, R. Djukanovic, M. Moore, S. Kirby, G. Yao, S. Zhu, E. Arden-Close, M. Thiruvothiyur, F. Webley, M Stafford-Watson, E. Dixon and L. Taylor
Type: Article | 2017

Parental perceptions of hypothermia treatment for neonatal hypoxic- ischaemic encephalopathy - Balamurugan Thyagarajan, Vijay Baral, Ranjit Gunda, Denise Hart, Lisa Leppard and Brigitte Vollmer
Type: Article | 2017

Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA - Yuan Tian, Mariana Babor, Jerome Lane, Veronique Schulten, Veena S Patil, Grégory Seumois, Sandy L Rosales, Zheng Fu, Gaelle Picarda, Julie Burel, Jose Zapardiel-Gonzalo, Rashika N. Tennekoon, Aruna D. De Silva, Sunil Premawansa, Gayani Premawansa, Ananda Wijewickrama, Jason A. Greenbaum, Pandurangan Vijayanand, Daniela Weiskopf, Alessandro Sette and Bjoern Peters
Type: Article | 2017

The clonal iNKT cell repertoire in people with type 1 diabetes is characterized by a loss of clones expressing high-affinity T cell receptors - Anna S. Tocheva, Salah Mansour, Tristan G.H. Holt, Samuel Jones, Andrew Chancellor, Joseph P. Sanderson, Efrem Eren, Timothy Elliott, Richard Holt and Stephan Gadola
Type: Article | 2017 | Item availability restricted.

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch - Joanne Tod, Christopher Hanley, Mark R. Morgan, Marta Rucka, Toby Mellows, Maria-Antoinette Lopez, Philip Kiely, Karwan Moutasim, Steven, James Frampton, Durgagauri Sabnis, David R. Fine, Colin Johnson, John F. Marshall, Giorgio Scita, Veronika Jenei and Gareth Thomas
Type: Article | 2017

International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia - Antoni Torres, Michael S. Niederman, Jean Chastre, Santiago Ewig, Patricia Fernandez-Vandellos, Hakan Hanberger, Marin Kollef, Gianluigi Li Bassi, Carlos M. Luna, Ignacio Martin-Loeches, J. Artur Paiva, Robert C. Read, David Rigau, Jean François Timsit, Tobias Welte and Richard Wunderink
Type: Article | 2017 | Item not available on this server.

Type: Article | 2017

Endothelial keratoplasty: is Descemet membrane endothelial keratoplasty the Holy Grail of lamellar surgery? No - Michael Tsatos, V Liarakos, C. Macgregor, I. Athanasiadis, ET Detorakis, M Moschos, Parwez Hossain and David F Anderson
Type: Article | 2017 | Item availability restricted.

Type: Article | 2017

Corticosteroid-responsive focal granulomatous herpes simplex type-1 encephalitis in adults - Aravinthan Varatharaj, James A.R. Nicoll, Emanuela Pelosi and Ashwin A. Pinto
Type: Article | 2017

Rapid test for lung maturity, based on spectroscopy of gastric aspirate, predicted respiratory distress syndrome with high sensitivity - Henrik Verder, Christian Heiring, Howard Clark, David Sweet, Torben E. Jessen, Finn Ebbesen, Lars J. Björklund, Bengt Andreasson, Lars Bender, Aksel Bertelsen, Marianne Dahl, Christian Eschen, Jesper Fenger-Grøn, Stine F. Hoffmann, Agnar Höskuldsson, Maria Bruusgaard-Mouritsen, Fredrik Lundberg, Anthony D. Postle, Peter Schousboe, Peter Schmidt, Hristo Stanchev and Lars Sørensen
Type: Article | 2017

Graphene oxide-upconversion nanoparticle based optical sensors for targeted detection of mRNA biomarkers present in Alzheimer’s disease and prostate cancer - Patrick Vilela, Afaf El-sagheer, Timothy M. Millar, Tom Brown, Otto L. Muskens and Antonios G. Kanaras
Type: Article | 2017

Correlation between white matter microstructure and executive functions suggests early developmental influence on long fibre tracts in preterm born adolescents - Brigitte Vollmer, Aiko Lundequist, Gustaf Mårtensson, Zoltan Nagy, Hugo Lagercrantz, Ann-Charlotte Smedler and Hans Forssberg
Type: Article | 2017

Matrix degradation in human immunodeficiency virus type 1–associated tuberculosis and tuberculosis immune reconstitution inflammatory syndrome: a prospective observational study - N.F. Walker, K.A. Wilkinson, G. Meintjes, L.B. Tezera, R. Goliath, J.M. Peyper, R. Tadokera, C. Opondo, A.K. Coussens, R.J. Wilkinson, J.S. Friedland and P.T. Elkington
Type: Article | 2017

Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenza biofilm formation - Woolf Walker, Claire Jackson, Raymond Allan, Samuel, Anthony Collins, M.J. Kelso, Ardeshir Rineh, Nageshwar R. Yepuri, Benjamin L. Nicholas, Laurie Lau, David Johnston, Peter Lackie, Saul Faust, Jane Lucas and Luanne Hall-Stoodley
Type: Article | 2017

Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition - Liesl Wandrag, Mario Siervo, Heather Riley, Maryam Khosravi, Bernadette Fernandez, Carl A. Leckstrom, Daniel S. Martin, Kay Mitchell, Denny Z.H. Levett, Hugh E. Montgomery, Monty G. Mythen, Michael A. Stroud, Michael Grocott and Martin Feelisch
Type: Article | 2017

First-in-human studies of seletalisib, an orally bioavailable small-molecule PI3Kδ inhibitor for the treatment of immune and inflammatory diseases - Mark Watling, Emma Jones, Dominique Tytgat, Mark Jones, Rodger Allen, Andrew Payne, Annelize Koch and Eugene Healy
Type: Article | 2017

The effect of beta-blockade on objectively measured physical fitness in patients with abdominal aortic aneurysms - a blinded interventional study - M.A. West, M. Parry, R. Asher, A. Key, P. Walker, L. Loughney, S. Pintus, N. Duffy, S. Jack and F. Torella
Type: Article | 2017 | Item not available on this server.

Prehabilitation and nutritional support to improve perioperative outcomes - Malcolm A. West, Paul E. Wischmeyer and Michael P.W. Grocott
Type: Article | 2017

Type: Article | 2017

Type: Article | 2017

Airway hyperresponsiveness does not predict morbidity in children with sickle cell anemia - Shaina M Willen, Mark Rodeghier, Robert C Strunk, Carol L Rosen, Fenella J Kirkham, Joshua J Field, Michael R DeBaun and Robyn T Cohen
Type: Article | 2017

Seasonality, risk-factors and burden of community-acquired pneumonia in COPD patients: A population database study using linked healthcare records - Nicholas P Williams, Ngaire A Coombs, Matthew Johnson, Lynn Josephs, Lucy Rigge, Karl J. Staples, Mike Thomas and Tom M A Wilkinson
Type: Article | 2017

Type: Article | 2017

Loss of Clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways - Aleksandra Wojtas, Silvia Kang, Benjamin Olley, Maureen Gatherer, Mitsuru Shinohara, Patricia Lozano, Chia-Chen Liu, Aishe Kurti, Kelsey Baker, Dennis Dickson, Mei Yue, Leonard Petrucelli, Guojun Bu, Roxana Carare and John D. Fryer
Type: Article | 2017

3D histopathology-a lung tissue segmentation workflow for microfocus X-ray-computed tomography scans - Lasse Wollatz, Steven J. Johnston, Peter M. Lackie and Simon J. Cox
Type: Article | 2017

Head and neck squamous cell carcinomas are characterized by a stable immune signature within the primary tumor over time and space - Oliver Wood, James Clarke, Jeogmin Woo, Adal H. Mirza, Christopher H. Woelk, Gareth J. Thomas, Pandurangan Vijayanand, Emma V. King and Christian H. Ottensmeier
Type: Article | 2017

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia - E Young, D Noerenberg, L Mansouri, V Ljungström, M Frick, L-A Sutton, S J Blakemore, J Galan-Sousa, K Plevova, P Baliakas, D Rossi, R Clifford, D Roos-Weil, V Navrkalova, B Dörken, C A Schmitt, K E Smedby, G Juliusson, B Giacopelli, J S Blachly, C Belessi, P Panagiotidis, N Chiorazzi, F Davi, A W Langerak, D Oscier, A Schuh, G Gaidano, P Ghia, W Xu, L Fan, O A Bernard, F Nguyen-Khac, L Rassenti, J Li, T J Kipps, K Stamatopoulos, S Pospisilova, T Zenz, C C Oakes, J C Strefford, R Rosenquist and F Damm
Type: Article | 2017 | Item not available on this server.

Character-complexity effects in Chinese reading and visual search: A comparison and theoretical implications - Lili Yu, Qiaoming Zhang, Caspian Priest, Erik Reichle and Heather Sheridan
Type: Article | 2017

Persistent kallikrein5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity - Yanan Zhu, Joanne Underwood, Derek Macmillan, Leila Shariff, Ryan O'Shaughnessy, John I. Harper, Chris Pickard, Peter Friedmann, Eugene Healy and Wei-Li Di
Type: Article | 2017

Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy: a birth cohort study - Ali H Ziyab, Susan Ewart, Gabrielle A Lockett, Hongmei Zhang, Syed Arshad, John W Holloway and Wilfried Karmaus
Type: Article | 2017

Type: Article | 2017

Book

CBT: Values and Ethics - David Kingdon, Nicholas Maguire, Dzintra Stalmeisters and Michael Townend
Type: Book | 2017 | Sage Publishing | Item not available on this server.

Custodio Garcia, para salvarles - Carmen Martin De Leon and Tilman Sanchez-Elsner
Type: Book | 2017 | Editorial Verbum | Item not available on this server.

Book Section

Investigating the lymphatic drainage of the brain: essential skills and tools - Nazira J. Albargothy, Matthew MacGregor Sharp, Maureen Gatherer, Alan Morris, Roy O. Weller, Cheryl Hawkes and Roxana O. Carare
Type: Book Section | 2017 | Humana Press | Item not available on this server.

Family-centred care - J.E. Davidson, J. McDuffie and K. Mitchell
Type: Book Section | 2017 | World Federation of Critical Care Nurses | Item not available on this server.

Type: Book Section | 2017 | Wiley-Blackwell | Item not available on this server.

Neuro-oncology - Colin Kennedy
Type: Book Section | 2017 | Oxford University Press | Item not available on this server.

Cooperative interactions between NO and H2S: chemistry, biology, physiology, pathophysiology - Christopher G. Kevil, Miriam M. Cortese-Krott, Péter Nagy, Andreas Papapetropoulos, Martin Feelisch and Csaba Szabo
Type: Book Section | 2017 | Academic Press | Item not available on this server.

Type: Book Section | 2017 | Elsevier | Item not available on this server.

Type: Book Section | 2017 | Springer Cham | Item not available on this server.

The lens - James Self and Christopher Lloyd
Type: Book Section | 2017 | Elsevier | Item not available on this server.

Quantitative assessment of cerebral basement membranes using electron microscopy - Matthew MacGregor Sharp, Anton Page, Alan Morris, Roy O. Weller and Roxana O. Carare
Type: Book Section | 2017 | Humana Press | Item not available on this server.

Conference or Workshop Item

Corticosteroid-resistant neutrophilic airway inflammation and hyperresponsiveness caused by il-13 - Elizabeth Davies, Joanne, Freda Carmichael Kelly, J.A. Whitsett, Stephen Holgate, Donna Davies and Hans Haitchi
Type: Conference or Workshop Item | 2017 | BMJ Group | Item not available on this server.

Type: Conference or Workshop Item | 2017 | British Neuroscience Association | Item not available on this server.

Type: Conference or Workshop Item | 2017 | Item not available on this server.

Type: Conference or Workshop Item | 2017 | Item not available on this server.

Type: Conference or Workshop Item | 2017 | Item not available on this server.

Type: Conference or Workshop Item | 2017 | Item availability restricted.

Membrane models for antibiotic delivery with polymersome nanoparticles - Prameen C. Kalikavunkal, Edoardo Scarpa, Tracey A. Newman and Maurits R.R. De Planque
Type: Conference or Workshop Item | 2017 | Item not available on this server.

Soluble adam33 augments the pulmonary immune response promoting allergic airway sensitivity - Joanne, Freda Carmichael Kelly, Elizabeth Davies, Stephen Holgate, X Xu, J.A. Whitsett, Donna Davies and Hans Haitchi
Type: Conference or Workshop Item | 2017 | BMJ Group | Item not available on this server.

Correlative microfocus computed tomography and fluorescence microscopy of fixed human lung tissue - M.J. Lawson, O.L. Katsamenis, O. J. Larkin, B. Smit, M. Olding, I. G.Haig, Ian Sinclair, P. Schneider, P.M. Lackie and J.A. Warner
Type: Conference or Workshop Item | 2017

Type: Conference or Workshop Item | 2017 | Item not available on this server.

Type: Conference or Workshop Item | 2017 | Item not available on this server.

Understanding the relationship between the perineuronal net and glia within the auditory pathway in a mouse model of age-related hearing loss - Shmma Quraishe, Genevieve Brixton, Bethan Impey, Edward Rogers, Carl Verschuur and Tracey Newman
Type: Conference or Workshop Item | 2017 | Item not available on this server.

Super-oscillatory polarisation contrast microscopy - Edward Rogers, Shmma Quraishe, John Chad, Tracey Newman, Nikolai Zheludev and P.J.S. Smith
Type: Conference or Workshop Item | 2017

Unlabelled super-resolution imaging using polarisation-contrast super-oscillatory microscopy - Edward T.F. Rogers, Shmma Quraishe, Tracey Newman, John Chad, Nikolai Zheludev and P.J.S. Smith
Type: Conference or Workshop Item | 2017

Optical super-oscillations: subwavelength single-photon focusing and unlabelled super resolution imaging - Edward T.F. Rogers, Shmma Quraishe, Guanghui Yuan, John Chad, P.J.S. Smith, Tracey Newman and Nikolai Zheludev
Type: Conference or Workshop Item | 2017 | Item not available on this server.

Electrode impedance: defining the norm - Edward T.F. Rogers, Alan P Sanderson, Tracey Newman and Carl Verschuur
Type: Conference or Workshop Item | 2017 | Item not available on this server.

Feature extraction and classification to diagnose hypoxic-ischemic encephalopathy patients by using susceptibility-weighted MRI images - Sisi Wu, Sasan Mahmoodi, Angela Darker, Brigitte Vollmer, Emma Lewis and Maria Liljeroth
Type: Conference or Workshop Item | 2017 | Springer

Monograph

Use of licensed medicines for unlicensed applications in Psychiatric practice: Psychopharmacology Committee - Katherine J. Aitchison, David S. Baldwin, Thomas Barnes, Jeremy Hall, Oliver Howes, R. Hamish McAllister-Williams, Ahmed Shoka, Paul Stokes and Allan Young
Type: Monograph | 2017 | Royal College of Psychiatrists | Item not available on this server.

Thesis

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Epithelial permeability in asthma - Patrick Winford Dennison
Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Type: Thesis | 2017 | University of Southampton

Dataset

Type: Dataset | 2017 | University of Southampton

Type: Dataset | 2017 | University of Cambridge | Item not available on this server.

Type: Dataset | 2017 | University of Southampton

Art Design Item

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C - Mohammed Naiyer, Sorcha A. Cassidy, Andrea Magri, Vanessa Cowton, Kevin Chen, Salah Mansour, Charikleia Kranidioti, Berenice Mbiribindi Nvunabandi, Pauline Rettman, Scott Harris, Liam J. Fanning, Franz H.J. Claas, Andrew D. Davidson, Arvind H. Patel, Marco A. Purbhoo and Salim Khakoo
Type: Art Design Item | 2017 | University of Southampton

Letter

Gene expression signatures in tuberculosis have greater overlap with autoimmune than infectious diseases - Kalum Clayton, Marta Polak, Christopher H. Woelk and Paul Elkington
Type: Letter | 2017

Type: Letter | 2017 | Item not available on this server.

Susceptibility to influenza virus infection of bronchial biopsies in asthma - Ben Nicholas, Sarah Dudley, Kamran Tariq, Peter Howarth, Kerry Lunn, Sarah Pink, Peter J. Sterk, Ian M. Adcock, Phillip Monk and Ratko Djukanovic
Type: Letter | 2017 | Item not available on this server.

Anti-cytokine autoantibodies in a patient with a heterozygous NFKB2 mutation - Kesava Ramakrishnan, William Rae, Gabriela Barcenas-Morales, Yifang Gao, Reuben Pengelly, Sanjay Patel, Dinkantha Kumararatne, Sarah Ennis, Rainer Doffinger, Saul N. Faust and Anthony Williams
Type: Letter | 2017

Accuracy of drain readings by surgical healthcare professionals - S. Shankla, T.C. Biggs, H.J. Cox and E.V. King
Type: Letter | 2017 | Item not available on this server.

Type C TP53-CDKN1A pathway dysfunction occurs independently of CDKN1A gene polymorphisms in chronic lymphocytic leukaemia and is associated with TP53 abnormalities - Ian Tracy, William Tapper, Anton Parker, Anne Gardiner, Shalal Sadullah, Guy Pratt, Adrian Copplestone, David Oscier and Oliver Giles Best
Type: Letter | 2017 | Item not available on this server.

Informing pneumococcal conjugate vaccine policy in middle-income countries: the case of Malaysia - Serena Tricarico, Hannah C. McNeil, Michael G. Head, David W. Cleary and Stuart C. Clarke
Type: Letter | 2017

Herpes simplex virus keratitis: an update of the pathogenesis and current treatment with oral and topical antiviral agents – comment - Michael Tsatsos, Cheryl MacGregor, Ioannis Athanasiadis, Marilita M. Moschos, Sazan Jameel, Parwez Hossain and David Anderson
Type: Letter | 2017 | Item not available on this server.

Editorial

Type: Editorial | 2017

Oxygen therapy and the Goldilocks principle - Daniel Martin and Michael Grocott
Type: Editorial | 2017 | Item availability restricted.

Type: Editorial | 2017

Review

Type: Review | 2017 | Item not available on this server.

Stable isotope analysis of dynamic lipidomics - Joost Brandsma, Andrew P. Bailey, Grielof Koster, Alex P. Gould and Anthony D. Postle
Type: Review | 2017

Type: Review | 2017

The nasopharyngeal microbiome - David W. Cleary and Stuart C. Clarke
Type: Review | 2017

Microglia and brain plasticity in acute psychosis and schizophrenia illness course: a meta-review - Livia J. De Picker, Manuel Morrens, Steven A. Chance and Delphine Boche
Type: Review | 2017

Reactive oxygen: a novel antimicrobial mechanism for targeting biofilm-associated infection - Matthew Dryden, Jonathan Cooke, Rami Salib, Rebecca, Emma Holding, Timothy, Charles Biggs, ALI SALAMAT, Raymond Allan, Rachel Newby, Fenella D. Halstead, Beryl Oppenheim, Thomas Haller, S Cox, Liam Grover, Zain Al-hindi, Lilyann Novak-Frazer and Malcolm Richardson
Type: Review | 2017

Type: Review | 2017

Acinetobacter spp. infections in Malaysia: a review of antimicrobial resistance trends, mechanisms and epidemiology - Farahiyah Mohd Rani, Nor Iza A. Rahman, Salwani Ismail, Ahmed Ghazi Alattraqchi, David W. Cleary, Stuart C. Clarke and Chew Chieng Yeo
Type: Review | 2017

Secondary bacterial infections associated with influenza pandemics - Denise Morris, David Cleary and Stuart Clarke
Type: Review | 2017

Idiopathic pulmonary fibrosis - Luca Richeldi, Harold R. Collard and Mark G. Jones
Type: Review | 2017

Personalized medicine in interstitial lung diseases - Paolo Spagnolo, Justin Oldham, Mark Jones and Joyce Lee
Type: Review | 2017

The blood-brain barrier in systemic inflammation - Aravinthan Varatharaj and Ian Galea
Type: Review | 2017

Extracellular vesicle flow cytometry analysis and standardization - Joshua A. Welsh, Judith A. Holloway, James S. Wilkinson and Nicola A. Englyst
Type: Review | 2017

Meeting abstract

The response of macrophages to Moraxella catarrhalis infection - Jodie Ackland, Joshua Wallington, David Cleary, Myron Christodoulides and Karl Staples
Type: Meeting abstract | 2017 | Item not available on this server.

Clinical importance of DNA methylation signatures in chronic lymphocytic leukaemia patients treated with chemo-immunotherapy - Harindra Amarasinghe, Tomasz K. Wojdacz, Matthew John Jerome Rose-Zerilli, Alice Beattie, Jade Forster, Latha Kadalayil, Stuart Blakemore, Helen Parker, Marta Larrayoz, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J. Steele, Richard Rosenquist, Andrew Collins, Andrew Pettitt, Peter Hillmen, Pauline Robbe, Christopher Plass, Anna Schuh, Daniel Catovsky, David Oscier, Christopher C. Oakes and Jonathan C. Strefford
Type: Meeting abstract | 2017 | Item not available on this server.

Central and systemic inflammation in Dementia with Lewy bodies and Alzheimer's disease - J. Amin, T. Williams, J. Teeling, R. Dorey, D. Williams, E. Tommasino, D. Boche and C. Holmes
Type: Meeting abstract | 2017 | Item not available on this server.

The contribution of gene mutations to long-term clinical outcomes: data from the randomised UK LRF CLL4 trial - Stuart Blakemore, Ruth Clifford, Pavlos Antoniou, Helen Parker, Pauline Robbe, Marta Larrayoz, Zadie Davis, Latha Kadalyayil, Andrew Collins, Jade Forster, Monica Else, Andrew J. Steele, Jacqueline Chan, Graham Speight, Mark Cragg, Matthew John Jerome Rose-Zerilli, Daniel Catovsky, David Oscier, Anna Schuh and Jonathan C. Strefford
Type: Meeting abstract | 2017 | Item not available on this server.

Type: Meeting abstract | 2017 | Item not available on this server.

Predictors of sputum and BAL eosinophilia in the Wessex Severe Asthma Cohort - Thomas Jones, Thomas Brown, Scott Elliott, Clair Barber, Kerry Gove, Laurie Lau, Hitasha Rupani, Anoop Chauhan, Peter Howarth, Junya Ono and Kenji Izuhara
Type: Meeting abstract | 2017 | Item not available on this server.

Characteristics of eosinophilic severe asthmatics in the Wessex Severe Asthma Cohort (WSAC) - Thomas Jones, Thomas Brown, Scott Elliott, Hitasha Rupani, Anoop Chauhan, Clair Barber, Kerry Gove, Laurie Lau and Peter Howarth
Type: Meeting abstract | 2017 | Item not available on this server.

Cell counts in severe asthma: concordance of sputum and BAL in Wessex Severe Asthma Cohort - Thomas Jones, Thomas P. Brown, Scott P. Elliott, Hitasha Rupani, Anoop Chauhan, Kerry Gove, Clair Barber, Laurie Lau and Peter Howarth
Type: Meeting abstract | 2017 | Item not available on this server.

Type: Meeting abstract | 2017 | Item not available on this server.

Defining gaps in dermatitis care - Susan Nedorost, Amber Atwater, Michael Ardern-Jones, Peter Elias, Pranab Mukherjee, Golara Honari, Mary Ertel, Maggie Hammond, Brian Machler, Andrew Scheman, Kammy Mulligan, Marjorie Montanez-Wiskovich, Sharon Jacob and Bruce Brod
Type: Meeting abstract | 2017

New super-oscillatory technology for unlabelled super-resolution cellular imaging with polarisation contrast - Edward Rogers, Shmma Quraishe, John Chad, Tracey Newman, Nikolai Zheludev and P.J.S. Smith
Type: Meeting abstract | 2017

A human 3D neural culture model utilising induced pluripotent stem cells from an Alzheimer's patient to study mechanisms of Alzheimer disease pathology - Elodie J. Siney, Preeti Prasannan, Shreyasi Chatterjee, Mariana Vargas-Caballero, Amritpal Mudher and Sandrine Willaime-Morawek
Type: Meeting abstract | 2017 | Item not available on this server.

Type: Meeting abstract | 2017 | Item not available on this server.

Other

Type: Other | 2017 | Department for Environment, Food & Rural Affairs

Type: Other | 2017 | Item not available on this server.

This list was generated on Tue Dec 17 02:24:26 2024 GMT.
Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×